I, Joseph P. Slattery, hereby certify pursuant
to Rule 13a-14(b) or Rule 15d-14(b) of the Securities Exchange Act of 1934 and 18 U.S.C. Section 1350, that the Quarterly
Report on Form 10-Q of TranS1 Inc. for the quarterly period ended September 30, 2012 (the “Report”) fully complies
with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934 and that the information contained
in the Report fairly presents, in all material respects, the financial condition and results of operations of TranS1 Inc.
|Date: November 8, 2012
/s/ Joseph P. Slattery
||Joseph P. Slattery|
||Executive Vice President and Chief Financial Officer|
This certification accompanies the
Report pursuant to Rule 13a-14(b) or Rule 15d-14(b) under the Securities Exchange Act of 1934 and 18 U.S.C. Section 1350
and shall not be deemed filed by the Company for purposes of Section 18 of the Securities Exchange Act of 1934 or otherwise
subject to the liability of that section. This certification will not be deemed to be incorporated by reference into any filing
under the Securities Act of 1933 or the Securities Exchange Act of 1934, except to the extent that the Company specifically incorporates
it by reference.