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8-K - Nemaura Medical Inc. | nemaura8k031115.htm |
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Nemaura Medical Inc.
(NMRD)
ROTH Conference Presentation
March 11th 2015
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Presentation Overview
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Our Background
Founded in January 2009 by Dr D F Chowdhury, the majority shareholder and the CEO
Biotech diagnostics research focused, headquarters in United Kingdom
Research facilities location at Science Park, Loughborough University, UK
Proprietary technology on transdermal (works through the skin) applications
diagnostic technologies
drug delivery technologies
Owned a family of related patents across various continents
Monitor commercialization process through sub-contracting to expert production and marketing vendors
Trading on NASDAQ OTC BB ticker: NMRD
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Key events
Date | Event |
2009-14 2012 2014 2014 2015 2015 | Cumulatively received over $2M in discretionary grants from UK government bodies Successfully completed proof of concept studies in human volunteers Secured UK licensee for glucose monitoring with $1.65m upfront Received trading symbol for OTC BB Successfully completed clinical study in Type 1 and 2 diabetics Awaiting approval for CE kite mark allowing sales of first product in Europe, HK and Saudi Arabia |
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Our Core Business
Platform technology developed for Drug Delivery and Diagnostic Applications.
Current Focus: (Diagnostic Applications)
Non-invasive, continuous and painless monitoring of analyte / molecules. For example: glucose, lactate, prescription drugs.
Future Focus: (Drug Delivery)
Drug Delivery complementing diagnostic application.
For example, non invasive insulin delivery working in tandem with non invasive continuous glucose monitoring.
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Management Overview
Core Team of 21 People consisting of:
5 Board Members
4 Science Advisory Team Members
12 Technical Team Members
CEO: Dr D F Chowdhury: Microsystems and Nanotechnology from Cranfield University and PhD from the University of Oxford in nano-drug delivery; over 18 patents pending/granted.
CFO: K Farrar: MChem from University of Oxford, Chartered Accountant, 10 years with KPMG.
CTO: Prof. K. Khan: Launched over 60 products during his career in the Pharmaceutical Industry.
Medical Device & Regulatory Director: R Carson A Pharmacologist with 20+ years experience in medical device design and registration in Europe and US.
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Government Support
Recipient of over $2m in several separate UK government grants awarded under independent competitive tendering process.
Grants awarded by UK Government Technology Strategy Board. Independent government assessor quoted:
The product could be a game changing technology.
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Our Patents
Patents granted:
Region | Purpose | Expires |
EU, China, Hong Kong | Patches patent for reverse iontophoresis: Device patent describing construction of patches Device patent for extracting glucose from skin non- invasively. | June 2028 |
Europe, USA, Canada | Method patent for measuring relative level of two substances Method patent to avoid finger prick to calibrate device | June 2021 |
Patents submitted:
Region | Purpose | Date applied/ Expiry |
Australia, Brazil, Canada, India, Japan, | Patch patent for Reverse Iontophoresis Device patent for construction of patches Device patent for extracting glucose non-invasively. | June 2008/ June 2028 |
USA, Canada, Brazil, Europe, Japan, China, India, Australia, Qatar, United Arab Emirates | Method patent for cumulative measurement of analyte Algorithm patent for measurement of analyte without long delays | May 2012/ May 2032 |
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sugarBEAT Product
Our first commercialized product
sugarBEAT
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sugarBEAT Product
sugarBEAT consists of three parts;
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a disposable patch (Patch)
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bluetooth enabled device (Device)
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smart phone app (App)
To use sugarBEAT:
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Affix Patch to arm
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Connect Patch to adjacently worn Device via thin wire
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Device transmits real time data to App
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App can send data online to remote health care team
sugarBEAT provides up to 4 readings an hour for 12 hours or more.
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sugarBEAT Product How it Works
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sugarBEAT Product - Clinical Need
Diabetics suffer from unstable blood glucose levels
Diabetics therefore need to constantly monitor glucose levels.
Currently the most common monitoring method involves:
Extracting a drop of blood (droplet) by piercing the skin (finger pricking) several times a day.
This droplet is placed onto a test strip to provide a glucose reading.
Other methods require intrusive insertion into subcutaneous tissue.
The test strip market alone is currently generating over $10 Billion sales per annum.
There is huge demand for our non intrusive and continuous monitoring method, which is convenient, timely and painless.
Our method will also provide substantial savings to diabetic patients.
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sugarBEAT Product Image of Device
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sugarBEAT Product Illustration of AP
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Our Technology - sugarBEAT
Technical basis:
Works by passing a mild current across the skin that is barely perceptible, or non-perceptible.
This current pulls the glucose out of interstitial fluid, which is found just below the top layer of skin, into a reservoir in the patch.
The patch contains a sensor, which measures the amount of glucose analyzed.
An algorithm within the device converts this reading to a glucose concentration value.
This reading is displayed on the device with sound and / or buzzer alert
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Our Clinical Trials for sugarBEAT
Clinical Data in Type I and II Diabetics: Interim data accuracy in Clark Error Zones A+B >85% 20 subjects/60 patient day studies tested in 1,179 paired data points* Note: Interim data presented in adjacent chart. Data validation currently in progress. *Hemocue vs CGM |
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Regulatory Approval for sugarBEAT
CE mark applied for which will permit sales in:
European Union countries
Saudi Arabia
Honk Kong
US and Japan Regulatory Approval to be sought 2016 onwards
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Target Market Analysis for sugarBEAT Product
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Why sugarBEAT better than competition?
Competitors using invasive continuous technology have the following cons:
Cost much more expensive
User market mostly only suitable for type 1 diabetics which are only 10% of total diabetic market
Comfort all require the continuous insertion of a measuring device into the body tissue which has high degree of user discomfort
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Why sugarBEAT better than competition?
Competitors using finger prick technology suffer following cons:
Finger prick is painful
Finger prick is not continuous most users only finger prick 1-2 times a day even though WHO recommends 5-7 times a day
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Commercialization Process for sugarBEAT
Manufacturing Development of Devices Q2-Q4 2015
Manufacturing Development of Patches Q2-Q4 2015
Mobile App development and launch Q4 2015
Product Launch in HK, Saudi Arabia Q4 2015
Product Launch in UK Q1 2016
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Production and Operations for sugarBEAT
We are dedicated R&D company.
All manufacture and sales therefore subcontracted to expert partners.
Preferred partners selected for:
Device manufacture
Sensor Manufacture
Patch Manufacture
Electronics
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Sales & Distribution for sugarBEAT
Criteria for selecting specialist partners: (partner already selected for UK)
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Financial Forcasts for sugarBEAT
In Million ($ US Dollar)/ Year to March 31, | 2016 | 2017 | 2018 | 2019 | 2020 |
Revenue | 10 | 85 | 270 | 461 | 694 |
Cost of sales | 7 | 42 | 136 | 244 | 366 |
Gross profits | 3 | 43 | 134 | 217 | 328 |
Total expenses | 10 | 15 | 14 | 24 | 29 |
Income before taxation | (7) | 28 | 120 | 193 | 299 |
Taxation | - - | 6 | 24 | 38 | 59 |
Net income | (7) | 22 | 96 | 155 | 240 |
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Our Future Potential Drug Delivery
Works by inverting technology so drugs delivered non-invasively into skin via a reservoir in the patch.
Technology suitable for:
Programmed drug delivery
On-demand drug delivery
Chrono-therapeutic drug delivery
Closed loop diagnostic and drug delivery
Basal Insulin expected to be first product chosen
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Contacts
Dr D F Chowdhury Nemaura Medical Inc. Holywell Park Ashby Road Loughborough Leics, LE11 3AQ UK Tel: +44 1509 222 912 Email: faz.chowdhury@nemaura.co. uk www.nemauramedical.com | Bashir Timol Nemaura Medical Inc. Holywell Park Ashby Road Loughborough Leics, LE11 3AQ UK Tel: +44 1509 222 912 Email: bashir.timol@nemaura.co.uk |
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