Attached files
| file | filename |
|---|---|
| 10-K - FORM 10-K - Shire plc | dp53559_10k.htm |
| EX-31.1 - EXHIBIT 31.1 - Shire plc | dp53559_ex3101.htm |
| EX-31.2 - EXHIBIT 31.2 - Shire plc | dp53559_ex3102.htm |
| EX-23.2 - EXHIBIT 23.2 - Shire plc | dp53559_ex2302.htm |
| EX-23.1 - EXHIBIT 23.1 - Shire plc | dp53559_ex2301.htm |
| EX-32.1 - EXHIBIT 32.1 - Shire plc | dp53559_ex3201.htm |
| EXCEL - IDEA: XBRL DOCUMENT - Shire plc | Financial_Report.xls |
EXHIBIT 21
LIST OF SUBSIDIARIES
|
Subsidiary/undertaking
|
Jurisdiction of incorporation
|
|
Advanced BioHealing Corp
|
United States
|
|
Auralis Limited
|
United Kingdom
|
|
Bikam Pharmaceuticals, Inc.
|
United States
|
|
DuoCort Pharma AB
|
Sweden
|
|
Farboud Pty Ltd
|
Australia
|
|
FerroKin BioSciences, Inc.
|
United States
|
|
Fibrotech Therapeutics Pty Ltd
|
Australia
|
|
Jerini Ophthalmic Holding GmbH
|
Germany
|
|
Jerini Ophthalmic, Inc
|
United States
|
|
JPT Peptide Technologies Inc
|
United States
|
|
Lotus Tissue Repair Inc
|
United States
|
|
Lumena Pharma UK Limited
|
United Kingdom
|
|
Lumena Pharmaceuticals LLC
|
United States
|
|
Monmouth Pharmaceuticals Limited
|
United Kingdom
|
|
Movetis GmbH
|
Germany
|
|
Movetis Limited
|
United Kingdom
|
|
Pharma International Insurance Limited
|
Ireland
|
|
Premacure AB
|
Sweden and Luxembourg
|
|
Premacure Uppsala AB
|
Sweden
|
|
Rybar Laboratories Limited
|
United Kingdom
|
|
SARcode Bioscience Inc.
|
United States
|
|
SHGT Executive Services Inc.
|
United States
|
|
Shire (Shanghai) Pharmaceuticals Consultancy Co., Ltd.
|
China
|
|
Shire 2005 Investments Limited
|
Cayman Islands
|
|
Shire Acquisitions UK Limited
|
United Kingdom
|
|
Shire Australia Pty Limited
|
Australia
|
|
Shire Belgium BVBA
|
Belgium
|
|
Shire Biopharmaceuticals Holdings
|
United Kingdom
|
|
Shire Biopharmaceuticals Holdings Ireland Limited
|
Jersey
|
|
Shire Biopharmaceuticals Ireland Limited
|
Ireland
|
|
Shire Brandywine LLC
|
United States
|
|
Shire Pharma Canada ULC
|
Canada
|
|
Shire Central & Eastern Europe GmbH
|
Germany
|
|
Shire Colombia S.A.S
|
Colombia
|
|
Shire Czech S.R.O.
|
Czech Republic
|
|
Shire Denmark ApS
|
Denmark
|
|
Shire Deutschland GmbH
|
Germany
|
|
Shire Deutschland Investments GmbH
|
Germany
|
|
Shire Development LLC
|
United States
|
|
Shire Europe Finance
|
United Kingdom
|
|
Shire Europe Limited
|
United Kingdom
|
|
Shire Executive Services LLC
|
United States
|
|
Shire Farmacêutica Brasil LTDA
|
Brazil
|
|
Shire Finance Limited
|
Cayman Islands
|
|
Shire Finland Oy
|
Finland
|
|
Shire France S.A.
|
France
|
|
Shire Global Finance
|
United Kingdom
|
|
Shire Hellas Pharmaceuticals Import Export and Marketing S.A.
|
Greece
|
|
Shire Holdings Europe B.V.
|
Netherlands
|
|
Shire Holdings Europe Limited
|
United Kingdom
|
|
Shire Holdings Europe No.2 S.a.r.l.
|
Luxembourg
|
|
Shire Holdings Ireland
|
Ireland
|
|
Shire Holdings Ireland No.2 Limited
|
Ireland
|
|
Shire Holdings Limited
|
Bermuda
|
|
Shire Holdings Luxembourg S.a r.l.
|
Luxembourg
|
|
Shire Holdings UK Canada Limited
|
United Kingdom
|
|
Shire Holdings UK Limited
|
United Kingdom
|
|
Shire Holdings US AG
|
United States
|
|
Shire Human Genetic Therapies (Canada) Inc.
|
Canada
|
|
Shire Human Genetic Therapies AB
|
Sweden
|
|
Shire Human Genetic Therapies Limited
|
United Kingdom
|
|
Shire Human Genetic Therapies S.A.
|
Argentina
|
|
Shire Human Genetic Therapies Securities Corporation
|
United States
|
|
Shire Human Genetic Therapies UK Limited
|
United Kingdom
|
|
Shire Human Genetic Therapies, Inc
|
United States
|
|
SHIRE ILAC TICARET LIMITED SIRKETI / Shire Pharmaceuticals Trading Limited Company
|
Turkey
|
|
Shire Incorporated
|
United States
|
|
Shire Intellectual Property 2 SRL
|
Barbados
|
|
Shire Intellectual Property Ireland Limited
|
Ireland
|
|
Shire Intellectual Property SRL
|
Barbados
|
|
Shire International GmbH
|
Switzerland
|
|
Shire International Licensing BV
|
Netherlands
|
|
Shire International Licensing VOF
|
Netherlands
|
|
Shire Investments & Finance (U.K.) Company
|
United Kingdom
|
|
Shire IP Services Corporation
|
Canada
|
|
Shire Ireland Finance Limited
|
Ireland
|
|
Shire Ireland Investment Limited
|
Ireland
|
|
Shire Ireland Premacure Investment
|
Ireland
|
|
Shire Italia S.p.A.
|
Italy
|
|
Shire Japan KK
|
Japan
|
|
Shire Jersey Limited
|
Jersey
|
|
Shire LLC
|
United States
|
|
Shire Luxembourg Finance S.a.r.l.
|
Luxembourg
|
|
Shire Luxembourg Intellectual Property No.2 S.a r.l.
|
Luxembourg
|
|
Shire Luxembourg Intellectual Property No.3 S.a.r.l.
|
Luxembourg
|
|
Shire Luxembourg Intellectual Property S.a r.l.
|
Luxembourg
|
|
Shire Luxembourg Sarl
|
Luxembourg
|
|
Shire North American Group Inc.
|
United States
|
|
Shire Norway AS
|
Norway
|
|
Shire Orphan and Rare Diseases GmbH
|
Switzerland
|
|
Shire Orphan Therapies GmbH
|
Germany
|
|
Shire Orphan Therapies, Inc.
|
United States
|
|
Shire Pharma Korea Yuhan Hoesa
|
Korea, Republic of
|
|
Shire Pharmaceutical Contracts Limited
|
United Kingdom
|
|
Shire Pharmaceutical Development Inc
|
United States
|
|
Shire Pharmaceutical Development Limited
|
United Kingdom
|
|
Shire Pharmaceutical Holdings Ireland Limited
|
Ireland
|
|
Shire Pharmaceutical Investment Trading Ireland
|
Ireland
|
|
Shire Pharmaceutical Investments 2008
|
Ireland
|
|
Shire Pharmaceuticals Group
|
United Kingdom
|
|
Shire Pharmaceuticals Iberica S.L.
|
Spain
|
|
Shire Pharmaceuticals International
|
Ireland
|
|
Shire Pharmaceuticals Investments (British Virgin Islands) Limited
|
Virgin Islands, British
|
|
Shire Pharmaceuticals Investments 2007
|
Ireland
|
|
Shire Pharmaceuticals Ireland Limited
|
Ireland
|
|
Shire Pharmaceuticals Limited
|
United Kingdom
|
|
Shire Pharmaceuticals LLC
|
United States
|
|
Shire Pharmaceuticals Mexico SA de CV
|
Mexico
|
|
Shire Pharmaceuticals Portugal, Lda
|
Portugal
|
|
Shire Pharmaceuticals Services Limited
|
United Kingdom
|
|
Shire Polska Sp. z o. o.
|
Poland
|
|
Shire Properties US
|
United States
|
|
Shire Regenerative Medicine LLC
|
United States
|
|
Shire Regulatory Inc
|
United States
|
|
Shire Rus Limited Liability Company
|
Russian Federation
|
|
Shire Singapore Pte. Ltd.
|
Singapore
|
|
Shire Supplies U.S. LLC
|
United States
|
|
Shire Sweden AB
|
Sweden
|
|
Shire Sweden Holdings S.a.r.l
|
Luxembourg
|
|
Shire UK Investments Limited
|
United Kingdom
|
|
Shire US Holdings LLC
|
United States
|
|
Shire US Inc
|
United States
|
|
Shire US Investment Inc
|
United States
|
|
Shire US Investments
|
United Kingdom
|
|
Shire US Manufacturing Inc
|
United States
|
|
Shire ViroPharma Incorporated
|
United States
|
|
Shire-Movetis NV
|
Belgium
|
|
Sparkleflame Limited
|
United Kingdom
|
|
Tanaud International BV
|
Netherlands
|
|
Tanaud Ireland Inc.
|
Ireland
|
|
The Endocrine Centre Limited
|
United Kingdom
|
|
VCO Incorporated
|
United States
|
|
ViroPharma AB
|
Sweden
|
|
Viropharma Biologics Inc
|
United States
|
|
Viropharma Canada Incorporated
|
Canada
|
|
Viropharma GmbH
|
Germany
|
|
Viropharma Holdings Limited
|
Bermuda
|
|
Viropharma Holdings LLC
|
United States
|
|
Viropharma Limited
|
United Kingdom
|
|
ViroPharma LLC
|
Switzerland
|
|
Viropharma Pty Ltd
|
Australia
|
|
Viropharma Puerto Rico Inc
|
Puerto Rico
|
|
Viropharma S.r.l
|
Italy
|
|
Viropharma SAS
|
France
|
|
Viropharma Spain SL
|
Spain
|
|
Viropharma SPRL
|
Belgium
|
|
Viropharma Sweden AB
|
Sweden
|
|
VPDE Incorporated
|
United States
|
|
VPINT Incorporated
|
United States
|
|
VPMP Incorporated
|
United States
|
All subsidiary undertakings of Shire plc are beneficially owned (directly or indirectly) as to 100% and are all consolidated in the consolidated financial statements of Shire plc.