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8-K - FORM 8-K - LIGAND PHARMACEUTICALS INC | d8k.htm |
Exhibit 99.1
Contacts: | ||
Ligand Pharmaceuticals Incorporated | Lippert/Heilshorn & Associates, Inc. | |
Rob McKay, Sr. Dir. Business Development | Don Markley | |
and Investor Relations | dmarkley@lhai.com | |
Erika Luib, Investor Relations | (310) 691-7100 | |
(858) 550-7896 |
Ligand Announces Fourth Quarter and Full Year 2010 Consolidated Financial Results
Results to be discussed during managements presentation at the BIO CEO &
Investor Conference today at 10:30 a.m. Eastern time
SAN DIEGO (February 15, 2011) Ligand Pharmaceuticals Incorporated (NASDAQ: LGND) today announced financial results for the three and 12 months ended December 31, 2010, and reviewed business highlights of the fourth quarter of 2010 and early 2011.
As we move into 2011, Ligand has the strongest portfolio of assets ever in the companys history and a bright future given the substantive anticipated news flow and the quality of our partnerships, said John L. Higgins, President and Chief Executive Officer of Ligand Pharmaceuticals. Ligand continues to execute well. In just over two years, we have completed five acquisitions, and in the same time have streamlined the company into a lean, efficient business. This year we are anticipating numerous major events from our collaborators including product launches, NDA filings and the announcement of Phase III data.
Fourth Quarter Results
Total revenues from continuing operations in the fourth quarter of 2010 were $3.9 million, compared with $14.0 million in the fourth quarter of 2009. The decrease in revenue of $10.1 million is primarily due to the termination of the Companys remaining collaboration agreements.
Operating expenses from continuing operations in the fourth quarter of 2010 were $10.3 million, compared with $13.1 million in the fourth quarter of 2009. Research and development expenses in the fourth quarter of 2010 were $3.2 million, a decrease of $7.0 million compared with the fourth quarter of 2009, primarily due to the elimination of costs associated with servicing collaboration agreements that have been terminated and the closing of the Companys New Jersey facility. General and administrative expenses increased by $0.5 million to $3.5 million, compared with the same period in 2009, primarily due to costs associated with the acquisitions of Neurogen and Metabasis, Inc.
Net income for the fourth quarter of 2010 was $2.4 million, or $0.12 per share, compared with net income of $3.0 million, or $0.16 per diluted share, in the fourth quarter of 2009. Income from continuing operations in the fourth quarter of 2010 was $2.3 million, or $0.12 per share, compared with income from continuing operations of $2.6 million, or $0.14 per share, in the comparable 2009 quarter. Income from discontinued operations in the fourth quarter of 2010 was $13,000, or $0.00 per share, compared with $0.5 million, or $0.02 per share, in the comparable 2009 quarter.
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As of December 31, 2010, Ligand had cash, cash equivalents, short-term investments and restricted investments of approximately $24 million. In addition, the Company had a $4.6 income tax receivable, which was collected subsequent to year-end, as well as other accounts receivables for a licensing deal completed in mid-December.
Full-Year Results
Total revenues for the year ended December 31, 2010 were $23.5 million, compared with $38.9 million for the same period in 2009. The decrease in revenues is primarily due to the termination of the Companys remaining collaboration agreements. Operating costs and expenses for the year ended December 31, 2010 were $54.5 million, including $16.9 million of lease exit and termination costs, compared with operating costs and expenses of $70.8 million, including $15.2 million of lease exit and termination costs, for the same period in 2009. The net loss for the year ended December 31, 2010 was $12.5 million, or $0.64 per share, compared with a net loss of $1.9 million, or $0.10 per share, for the same period in 2009. The net loss for 2009 includes $21.4 million of accretion of deferred gain on sale leaseback related to the acceleration of deferred gain recognized during the period as a result of the Companys building lease termination.
Select Business and Program Highlights
The following is a summary of business and key program highlights in the fourth quarter of 2010 and early 2011.
Business Highlights
| October 2010, Ligand divested its combinatorial chemical library and associated proprietary technology to Venenum Biodesign, LLC, for $1.8 million |
| October 2010, Sunil Patel was appointed to Ligands Board of Directors |
| November 2010, Ligand was awarded $2 million from the U.S. government under the Patient Protection and Affordable Care Act |
| January 2011, Ligand formed a strategic drug development alliance with Chiva Pharmaceuticals for the development of select clinical stage hepatitis B and liver cancer programs in China |
| January 2011, Ligand acquired CyDex Pharmaceuticals |
| February 2011, John L. LaMattina, Ph.D. was appointed to Ligands Board of Directors |
Program Highlights
Promacta® /Revolade® (TPO Receptor Agonist) GlaxoSmithKline
| Approved in Japan in November 2011 |
| Two Phase III hepatitis C trials targeted for completion in 3Q11 |
Viviant® /Conbriza® (SERMs) Pfizer
| Bazedoxifene launched in Japan (branded as Viviant) and Spain (branded as Conbriza) in 2H10 for the treatment of postmenopausal osteoporosis |
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Carfilzomib (proteasome inhibitor) Onyx Pharmaceuticals
| FDA granted fast track designation in January 2011 for carfilzomib for the potential treatment of patients with relapsed and refractory multiple myeloma. Onyx initiated filing a rolling NDA for carfilzomib with the FDA and expects submission to be completed by mid-2011 |
| International Phase III trial initiated (ASPIRE) for the potential treatment for patients with relapsed multiple myeloma |
SCH-527123 (CXCR2 Inhibitor) - Merck
| Phase II trial in COPD is fully enrolled with 500 patients targeted for completion in 3Q12 |
Dinaciclib (CDK Inhibitor) - Merck
| Multiple Phase II studies ongoing in various cancer types, including breast, AML, melanoma, and multiple myeloma. Trials are targeted for completion in 2011 and 2012 |
| Multiple clinical studies of dinaciclib reported at the American Society of Hematology (ASH) in December 2010 |
BMS-582949 (p38 Inhibitor) Bristol Myers Squibb (BMS)
| BMS presented Phase II data on BMS-582949 at the American College of Rheumatology (ACR) Annual meeting in November 2010 |
| BMS plans to initiate additional Phase II clinical trials on BMS-582949 in 2011 |
| Phase II trial for atherosclerosis is ongoing |
CC-930 (JNK Inhibitor) Celgene
| Phase II trial initiated in January 2011 for CC-930, a JNK inhibitor in idiopathic pulmonary fibrosis |
MEDI-528 (IL-9 Antibody) AstraZeneca
| Phase II trial in asthma fully enrolled with 320 patients with an expected study completion targeted for 3Q11 |
LGD-4033 (Ligand SARM Program)
| Preclinical molecular pharmacology data on LGD-4033 were presented at the 92nd Annual Meeting of the Endocrine Society in June 2010 |
| Phase Ib multiple ascending dose trial is ongoing |
2011 Financial Outlook
For 2011, Ligand currently estimates total revenues to be between $22 million to $24 million comprised of approximately $13 million to $14 million of revenue (partial year accounting) from the CyDex business, and approximately $9 million to $10 million of revenue from the original Ligand business, before any revenue for new licensing agreements.
Ligands 2011, operating expenses are currently estimated to be in the range of $16 million to $18 million, with an average cost of goods as a percentage of material sales to be approximately 35%. Ligand expects to determine the CyDex non-cash amortization expense in the near-term. By the end of 2011, Ligand expects its operations to be profitable and cash-flow positive.
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Webcast and Conference Call
Ligands President and Chief Executive Officer, John L. Higgins, will discuss fourth quarter financial results and provide a business update during a presentation at the BIO CEO & Investor Conference today at 10:30 a.m. Eastern time (7:30 a.m. Pacific time). The conference takes place at the Waldorf-Astoria Hotel in New York City. A live webcast of the presentation will be available on Ligands website www.ligand.com. To access the presentation via telephone please dial (877) 407-4019, passcode: Ligand. Slides accompanying the presentation will be available in the Investor Relations section of www.ligand.com.
A replay of the presentation will be archived for 30 days on www.ligand.com and via telephone at (877) 660-6853, Account: 361# passcode: 366800.
About Ligand Pharmaceuticals
Ligand is a BioPharma company with a business model that is based upon the concept of developing or acquiring royalty revenue generating assets and coupling them to an efficiently lean corporate cost structure. Ligands goal is to produce a bottom line that supports a sustainably profitable business. By diversifying the portfolio of assets across numerous technology types, therapeutic areas, drug targets, and industry partners, we offer investors a de-risked opportunity to invest in the increasingly complicated and unpredictable pharmaceutical industry. We believe Ligand has assembled one of the largest and most diversified portfolio of current assets in the industry for a company of its size, currently exceeding 60 programs, with the potential to generate revenue in the future. These therapies address the unmet medical needs of patients for a broad spectrum of diseases including hepatitis, muscle wasting, Alzheimers disease, dyslipidemia, diabetes, anemia, COPD, asthma, rheumatoid arthritis, osteoporosis and cancer. Ligand has established multiple alliances with the worlds leading pharmaceutical companies including GlaxoSmithKline, Merck, Pfizer, Bristol-Myers Squibb and AstraZeneca. For more information, please visit www.ligand.com.
Forward-Looking Statements
This news release contains certain forward-looking statements by Ligand that involve risks and uncertainties and reflect Ligands judgment as of the date of this release. Actual events or results may differ from Ligands expectations. For example, we may be profitable before the end of 2011, we may not receive expected revenue from CyDex product sales of Captisol®, we may not be able to effectively integrate CyDexs business into our current business, expected royalties on partnered products or from research and development milestones, and we and our partners may not be able to timely or successfully advance any product(s) in Ligands internal and partnered pipeline. In addition, there can be no assurance that Ligand will achieve its guidance for 2011, that Ligand will deliver strong cash flow over the long term, that Ligand will realize the expected benefits of the acquisition of CyDex, that Ligands 2011 revenues will be driven by royalty payments related and Captisol sales, that Ligand will be able to create future revenues and cash flows by developing innovative therapeutics, that results of any clinical study will be timely, favorable or confirmed by later studies, that products under development by Ligand or its partners will receive regulatory approval, or that there will be a market for the product(s) if successfully
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developed and approved. Also, Ligand and its partners may experience delays in the commencement, enrollment, completion or analysis of clinical testing for its product candidates, or significant issues regarding the adequacy of its clinical trial designs or the execution of its clinical trials, which could result in increased costs and delays, or limit Ligands ability to obtain regulatory approval. Further, unexpected adverse side effects or inadequate therapeutic efficacy of Ligands product(s) could delay or prevent regulatory approval or commercialization. Ligand may also have indemnification obligations to King Pharmaceuticals or Eisai in connection with the sales of the Avinza and oncology product lines and may be subject to future tax liabilities which are larger than the provision for income taxes reflected in Ligands 2010 year-end financial statements. In addition, Ligand may not be able to successfully implement its strategic growth plan and continue the development of its proprietary programs. The failure to meet expectations with respect to any of the foregoing matters may reduce Ligands stock price. Additional information concerning these and other risk factors affecting Ligands business can be found in prior press releases available via www.ligand.com as well as in Ligands public periodic filings with the Securities and Exchange Commission at www.sec.gov. Ligand disclaims any intent or obligation to update these forward-looking statements beyond the date of this release. This caution is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.
(Tables to follow)
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LIGAND PHARMACEUTICALS INCORPORATED
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(in thousands, except per share data)
Three Months
Ended December 31, |
Twelve Months
Ended December 31, |
|||||||||||||||
2010 | 2009 | 2010 | 2009 | |||||||||||||
Revenues: |
||||||||||||||||
Royalties |
$ | 1,942 | $ | 1,811 | $ | 7,279 | $ | 8,334 | ||||||||
Collaborative research and development and other revenues |
1,998 | 12,163 | 16,259 | 30,606 | ||||||||||||
Total revenues |
3,940 | 13,974 | 23,538 | 38,940 | ||||||||||||
Operating costs and expenses: |
||||||||||||||||
Research and development |
3,155 | 10,127 | 22,067 | 39,870 | ||||||||||||
General and administrative |
3,465 | 3,021 | 12,829 | 15,211 | ||||||||||||
Lease exit and termination costs |
954 | | 16,894 | 15,235 | ||||||||||||
Write-off of acquired in-process research and development |
2,754 | | 2,754 | 442 | ||||||||||||
Total operating costs and expenses |
10,328 | 13,148 | 54,544 | 70,758 | ||||||||||||
Accretion of deferred gain on sale leaseback |
426 | 425 | 1,702 | 21,851 | ||||||||||||
Gain (loss) from operations |
(5,962 | ) | 1,251 | (29,304 | ) | (9,967 | ) | |||||||||
Other income (loss) |
4,374 | (220 | ) | 13,901 | 95 | |||||||||||
Gain (loss) before income taxes |
(1,588 | ) | 1,031 | (15,403 | ) | (9,872 | ) | |||||||||
Income tax (expense) benefit |
3,936 | 1,535 | 2,617 | 1,535 | ||||||||||||
Income (loss) from continuing operations |
2,348 | 2,566 | (12,786 | ) | (8,337 | ) | ||||||||||
Discontinued operations: |
||||||||||||||||
Gain on sale of AVINZA Product Line before income taxes |
48 | 95 | 70 | 5,434 | ||||||||||||
Gain (loss) on sale of Oncology Product Line before income taxes |
(35 | ) | 372 | 201 | 955 | |||||||||||
Income tax benefit (expense) on discontinued operations |
| | | | ||||||||||||
Discontinued operations |
13 | 467 | 271 | 6,389 | ||||||||||||
Net income (loss) |
2,361 | 3,033 | (12,515 | ) | (1,948 | ) | ||||||||||
Basic and diluted per share amounts: |
||||||||||||||||
Loss from continuing operations |
0.12 | 0.14 | (0.65 | ) | (0.44 | ) | ||||||||||
Discontinued operations |
0.00 | 0.02 | 0.01 | 0.34 | ||||||||||||
Net income (loss) |
0.12 | 0.16 | (0.64 | ) | (0.10 | ) | ||||||||||
Weighted average number of common shares - basic |
19,630,764 | 18,896,985 | 19,613,201 | 18,862,752 | ||||||||||||
Weighted average number of common shares - diluted |
19,636,359 | 18,918,379 | 19,613,201 | 18,862,752 | ||||||||||||
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LIGAND PHARMACEUTICALS INCORPORATED
CONDENSED CONSOLIDATED BALANCE SHEETS
(in thousands)
December 31, 2010 |
December 31, 2009 |
|||||||
Assets |
||||||||
Current assets: |
||||||||
Cash, cash equivalents and short-term investments |
$ | 22,697 | $ | 53,232 | ||||
Accounts receivable, net |
993 | 618 | ||||||
Other current assets |
5,295 | 4,534 | ||||||
Current portion of co-promote termination asset |
8,034 | 9,782 | ||||||
Total current assets |
37,019 | 68,166 | ||||||
Restricted cash and investments |
1,341 | 1,462 | ||||||
Property and equipment, net |
559 | 8,522 | ||||||
Goodwill and other identifiable intangible assets |
12,951 | 2,515 | ||||||
Long-term portion of co-promote termination asset |
22,851 | 30,993 | ||||||
Other assets |
838 | 30,149 | ||||||
$ | 75,559 | $ | 141,807 | |||||
Liabilities and Stockholders Equity |
||||||||
Accounts payable and accrued liabilities |
$ | 25,894 | $ | 35,699 | ||||
Current portion of deferred gain |
1,702 | 1,702 | ||||||
Current portion of co-promote termination liability |
8,034 | 9,782 | ||||||
Current portion of deferred revenue |
| 4,989 | ||||||
Total current liabilities |
35,630 | 52,172 | ||||||
Long-term portion of co-promote termination liability |
22,851 | 30,993 | ||||||
Long-term portion of deferred revenue |
2,546 | 3,495 | ||||||
Long-term portion of deferred gain |
| 1,702 | ||||||
Other long-term liabilities |
13,179 | 41,357 | ||||||
Total liabilities |
74,206 | 129,719 | ||||||
Common stock subject to conditional redemption |
8,344 | 8,344 | ||||||
Stockholders equity (deficit) |
(6,991 | ) | 3,744 | |||||
$ | 75,559 | $ | 141,807 | |||||
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