Attached files
Exhibit
23.1
Consent
of Independent Registered Public Accounting Firm
We
consent to the incorporation by reference in the following Registration
Statements:
(1)
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Registration
Statement (Form S-8 No. 333-41532) pertaining to the Equity Incentive Plan
and to the Non-Employee Directors’ Stock Option Plan of Lexicon
Pharmaceuticals, Inc.,
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(2)
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Registration
Statement (Form S-8 No. 333-66380) pertaining to the Coelacanth
Corporation 1999 Stock Option Plan of Lexicon Pharmaceuticals,
Inc.,
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(3)
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Registration
Statement (Form S-3 No. 333-67294) of Lexicon Pharmaceuticals,
Inc.,
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(4)
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Registration
Statement (Form S-3 No. 333-108855) of Lexicon Pharmaceuticals,
Inc.,
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(5)
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Registration
Statement (Form S-3 No. 333-111821) of Lexicon Pharmaceuticals,
Inc.,
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(6)
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Registration
Statement (Form S-3 No. 333-144933) of Lexicon Pharmaceuticals, Inc.,
and
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(7)
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Registration
Statement (Form S-3 No. 333-161696) of Lexicon Pharmaceuticals,
Inc.
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of our
report dated March 5, 2010, with respect to the consolidated financial
statements of Lexicon Pharmaceuticals, Inc. incorporated herein by reference,
and our report dated March 5, 2010, with respect to the effectiveness of
internal control over financial reporting of Lexicon Pharmaceuticals, Inc.,
included in this annual report of Lexicon Pharmaceuticals, Inc. (Form 10-K) for
the year ended December 31, 2009.
/s/
ERNST & YOUNG LLP
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Houston,
Texas
March 5,
2010