Exhibit 99.1

DEXTERA SURGICAL REPORTS FISCAL 2017 THIRD QUARTER FINANCIAL RESULTS

-- Updates Fiscal 2017 Fourth Quarter Guidance --

REDWOOD CITY, Calif. – May 4, 2017 – Dextera Surgical Inc. (Nasdaq: DXTR), a company developing and commercializing the MicroCutter 5/80™ stapler based on its proprietary ‘‘staple-on-a-strip’’ technology intended for use by thoracic, pediatric, colorectal and general surgeons, today announced financial results for its fiscal third quarter and nine months ended March 31, 2017. Management will hold a conference call at 4:30 p.m. Eastern Time to discuss financial results and provide an update on the company’s business.

“Product sales for the third quarter were approximately $1 million, favorably impacted by the initiation of sales in Spain as well as an uptick in our cardiac products,” said Julian Nikolchev, president and CEO of Dextera Surgical Inc. “Looking ahead, we see increasing demand for the MicroCutter in both Europe and the United States.”

Recent Highlights and Accomplishments:

For the 82 patients undergoing a Microlobectomy, the median length of hospital stay was three days, with 17 patients (20.7%) discharged the day after surgery and an additional 14 patients (17%) discharged two days after surgery. Data were presented at the Scandinavian Society for Research in Cardiothoracic Surgery 2017 held in Geilo, Norway.

Fiscal 2017 Third Quarter and Nine Months Ended March 31, 2017, Financial Results

Total product sales were approximately $1.0 million for the fiscal 2017 third quarter compared with $0.5 million for the same quarter of fiscal 2016. MicroCutter sales were approximately $516,000 in the fiscal 2017 third quarter compared to $19,000 in the comparable quarter last year and $284,000 in the second quarter of this fiscal year, demonstrating positive uptake and in line with the forecast in Dextera’s corporate update press release on January 5, 2017. Total revenue was approximately $1.1 million for the fiscal 2017 third quarter compared with approximately $1.9 million for the fiscal 2016 third quarter. Total revenue for the third quarter of fiscal 2016 included approximately $1.4 million in license revenue from the extension of Dextera Surgical’s agreement with Intuitive Surgical.

Total operating costs and expenses for the fiscal 2017 third quarter were $5.5 million, compared with $4.8 million for the same period of fiscal 2016. Cost of product sales was approximately $1.3 million compared with $0.9 million for the same period of fiscal 2016. Research and development expenses were $2.0 million for the fiscal 2017 third quarter, compared with $1.6 million for the fiscal 2016 third quarter. Selling, general and administrative expenses were $2.1 million for the fiscal 2017 third quarter, compared with $2.3 million for the fiscal 2016 third quarter.

The net loss for the fiscal 2017 third quarter was approximately $4.5 million, or $0.50 per share, compared with a net loss of approximately $3.0 million, or $0.34 per share, for the fiscal 2016 third quarter.

Cash, cash equivalents and investments, as of March 31, 2017, were approximately $2.5 million, compared with approximately $5.8 million at December 31, 2016. As of March 31, 2017, there were approximately 8.9 million shares of common stock outstanding and 191,474 shares of Series A convertible preferred stock outstanding.

Updated Financial Guidance

For the fourth quarter of fiscal 2017 ending June 30, 2017, Dextera expects to report MicroCutter product sales of $600,000 to $700,000, as opposed to previous guidance of $700,000 to $800,000. The revised guidance is due to a backorder on the blue reload cartridge. Total MicroCutter product sales for fiscal 2017 are expected to be $1.4 million to $1.5 million

Milestones

Management’s key objectives in the near term:

Conference Call Details

To access the live conference call on May 4, 2017, at 4:30 p.m. Eastern Time via phone, please dial 844-419-1785 from the United States and Canada or 216-562-0472. The conference ID is 13014350. Please dial in approximately 10 minutes prior to the start of the call. A telephone replay will be available beginning approximately four hours after the call through May 11, 2017, and may be accessed by dialing 855-859-2056 from the United States and Canada or 404-537-3406 internationally. The replay passcode is 13014350.

To access the live and subsequently archived webcast of the conference call, go to the Investor Relations section of the company’s website at ir.dexterasurgical.com. Please connect to the website at least 15 minutes prior to the presentation to allow for any necessary software downloads.

The webcast is also being distributed through the Thomson StreetEvents Network. Institutional investors can access the call via Thomson StreetEvents at www.streetevents.com, a password-protected event management site.

About Dextera Surgical

Dextera Surgical (Nasdaq:DXTR) designs and manufactures proprietary stapling devices for minimally invasive surgical procedures.

Dextera Surgical also markets automated anastomosis devices for coronary artery bypass graft (CABG) surgery on the market today: the C-Port® Distal Anastomosis Systems and PAS-Port® Proximal Anastomosis System. These products are sold by Dextera Surgical under the Cardica brand name.

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Forward-Looking Statements

The statements in this press release regarding Dextera Surgical’s expected sales for the fourth quarter of fiscal 2017, and the anticipated completion of the Company’s current public offering are "forward-looking statements." There are a number of important factors that could cause Dextera Surgical’s results to differ materially from those indicated by these forward-looking statements, including the risks detailed from time to time in Dextera Surgical’s reports filed with the U.S. Securities and Exchange Commission, including its Quarterly Report on Form 10-Q for the quarter ended December 31, 2016, under the caption “Risk Factors.” Dextera Surgical expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein. You are encouraged to read Dextera Surgical’s reports filed with the U.S. Securities and Exchange Commission, available at www.sec.gov.

Dextera Surgical has filed a registration statement (including a preliminary prospectus dated April 21, 2017) with the Securities and Exchange Commission, or SEC, for the offering to which this communication relates. Before you invest, you should read the preliminary prospectus and the other documents Dextera Surgical has filed with the SEC for more complete information about it and the offering. You may get these documents for free by visiting EDGAR on the SEC web site at www.sec.gov. Alternatively, Dextera Surgical, the underwriter or any dealer participating in the offering will arrange to send you copies if you request them by contacting Ladenburg Thalmann & Co. Inc., 277 Park Avenue, 26th Floor, New York, New York 10172 or by e-mail at prospectus@ladenburg.com.

Contact:

Bob Newell

Vice President, Finance and Chief Financial Officer

(650) 331-7133

investors@dexterasurgical.com

Dextera Surgical Inc.

Consolidated Statements of Operations

(amounts in thousands except per share amounts)

Consolidated Balance Sheets

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