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S-1 - S-1 - Rhythm Holding Company, LLCa2220945zs-1.htm
EX-3.1 - EX-3.1 - Rhythm Holding Company, LLCa2220945zex-3_1.htm
EX-10.7 - EX-10.7 - Rhythm Holding Company, LLCa2220945zex-10_7.htm
EX-10.12 - EX-10.12 - Rhythm Holding Company, LLCa2220945zex-10_12.htm
EX-10.11 - EX-10.11 - Rhythm Holding Company, LLCa2220945zex-10_11.htm
EX-10.8 - EX-10.8 - Rhythm Holding Company, LLCa2220945zex-10_8.htm
EX-10.9 - EX-10.9 - Rhythm Holding Company, LLCa2220945zex-10_9.htm
EX-21.1 - EX-21.1 - Rhythm Holding Company, LLCa2220945zex-21_1.htm
EX-23.1 - EX-23.1 - Rhythm Holding Company, LLCa2220945zex-23_1.htm
EX-10.10 - EX-10.10 - Rhythm Holding Company, LLCa2220945zex-10_10.htm
EX-10.13 - EX-10.13 - Rhythm Holding Company, LLCa2220945zex-10_13.htm

EXHIBIT 3.2

 

RHYTHM HOLDING COMPANY, LLC

 

FIRST AMENDMENT

TO

OPERATING AGREEMENT

 

This FIRST AMENDMENT TO OPERATING AGREEMENT (this “Amendment”) is entered into as of July 16, 2013, by and among the undersigned members of Rhythm Holding Company, LLC, a Delaware limited liability company (the “Company”).  Capitalized terms used herein but not defined shall have the meanings ascribed to such terms in the Operating Agreement (as defined below).

 

RECITALS

 

WHEREAS, the Company and its Members entered into that certain Operating Agreement, dated as of March 21, 2013 (the “Operating Agreement”);

 

WHEREAS, pursuant to Section 16.2 of the Operating Agreement, the Operating Agreement may be amended, supplemented, or modified upon the written consent of the Majority Preferred Members and the Majority Members; and

 

WHEREAS, the Company and the undersigned Members, constituting the Majority Preferred Members and the Majority Members, desire to amend the Operating Agreement.

 

NOW, THEREFORE, in consideration of the foregoing recitals and for other consideration, the adequacy and sufficiency of which is hereby acknowledged, the parties hereto agree as follows:

 

SECTION 1.  AMENDMENT TO OPERATING AGREEMENT

 

1.1                               SECTION 1.1.  Section 1.1 of the Operating Agreement is hereby amended to replace the definition of the term Exempted Securities with the following definition:

 

Exempted Securities” shall mean (i) the following Units and (ii) Units deemed issued pursuant to the following Options and/or Convertible Securities: (1) Antidilution Units issued pursuant to Section 4.9(a) hereof; (2) Common Units issued upon automatic conversion of  Preferred Units pursuant to Section 4.11 hereof; (3) Units the issuance of which is subject to adjustment pursuant to Section 4.10 hereof; (4) Units, Options or Convertible Securities issued by reason of a Qualified Initial Public Offering; (5) Units, Options or Convertible Securities issued as a dividend or distribution on outstanding Preferred Units; (6) Common Units or Options issued to employees or directors of, or consultants or advisors to, the Company or any of its subsidiaries pursuant to a plan, agreement or arrangement approved by the Board of Managers, including a majority of the Preferred Managers (including without limitation, up

 



 

to an aggregate of 20,309,000 Compensatory Units issued pursuant to Section 4.3); and (7) Units or Convertible Securities actually issued upon the exercise of Options or Units or Convertible Securities actually issued upon the conversion or exchange of Convertible Securities, in each case provided such issuance is pursuant to the terms of such Option or Convertible Security and that the Units or Convertible Securities so actually issued have previously been treated as deemed to be issued pursuant to Section 4.9(d) hereof.

 

1.3                               EXHIBIT A.  Exhibit A to the Operating Agreement is hereby to read in its entirety as set forth in Schedule I attached hereto.

 

1.4                               EXHIBIT B.  Exhibit B to the Operating Agreement is hereby amended to read in its entirety as set forth in Schedule II attached hereto.

 

1.5                               EXHIBIT C.  Exhibit C to the Operating Agreement is hereby amended to read as set forth in Schedule III attached hereto.

 

SECTION 2.  ADDITIONAL PROVISIONS

 

2.1                               ENTIRE AGREEMENT AND MODIFICATION.  The Operating Agreement, together with this Amendment, constitutes the entire agreement among the parties with respect to the subject matter thereof and hereof and supersedes any prior understandings, agreements, or representations by or among the parties, written or oral, to the extent they related in any way to the subject matter hereof.  Except as modified by this Amendment, all of the provisions of the Operating Agreement are hereby ratified, confirmed, and affirmed in all respects, and shall continue in full force and effect.  The Operating Agreement and this Amendment shall be read together, and any reference to the term “Agreement” in the Operating Agreement shall mean the Operating Agreement as amended by this Amendment.

 

2.2                               COUNTERPARTS.  This Amendment may be executed in counterparts, each of which shall be deemed an original but all of which together will constitute one and the same instrument.

 

2.3                               HEADINGS.  The Section headings contained in this Amendment are inserted for convenience only and shall not affect in any way the meaning or interpretation of this Amendment.

 

2.4                               SEVERABILITY.  Any term or provision of this Amendment that is invalid or unenforceable in any situation in any jurisdiction shall not affect the validity or enforceability of the remaining terms and provisions hereof or the validity or enforceability of the offending term or provision in any other situation or in any other jurisdiction.

 

[The remainder of this page is intentionally left blank.]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

COMPANY:

 

 

 

 

 

RHYTHM HOLDING COMPANY, LLC

 

 

 

 

 

By:

/s/ Bart Henderson

 

Name:

Bart Henderson

 

Title:

President

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES A MEMBERS:

 

 

 

 

 

MPM BIOVENTURES V, L.P.

 

By: MPM BIOVENTURES V GP LLC, its General Partner

 

By: MPM BIOVENTURES V LLC, its Managing Member

 

 

 

 

 

By:

/s/ Vaughn Kailian

 

Name:

Vaughn Kailian

 

Title:

Member

 

 

 

 

 

 

 

MPM ASSET MANAGEMENT INVESTORS BV5 LLC

 

By: MPM BIOVENTURES V LLC, its Manager

 

 

 

 

 

 

 

By:

/s/ Vaughn Kailian

 

Name:

Vaughn Kailian

 

Title:

Member

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES A MEMBERS:

 

 

 

 

 

New Enterprise Associates 13, L.P.

 

By: NEA Partners 13, L.P., its general partner

 

By: NEA 13 GP, LTD, its general partner

 

 

 

 

 

By:

/s/ Louis S. Citron

 

Name:

Louis S. Citron

 

Title:

Chief Legal Officer

 

 

 

 

 

 

 

NEA Ventures 2009, Limited Partnership

 

 

 

 

 

 

 

By:

/s/ Louis S. Citron

 

Name:

Louis S. Citron

 

Title:

Vice President

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES A MEMBERS:

 

 

 

 

 

Third Rock Ventures, L.P.

 

By: Third Rock Ventures GP, L.P., its general partner

 

By: TRV GP, LLC, its general partner

 

 

 

 

 

By:

/s/ Louis A. Tartaglia

 

Name:

Louis A. Tartaglia

 

Title:

Partner

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES B MEMBERS:

 

 

 

 

 

MPM BIOVENTURES V, L.P.

 

By: MPM BIOVENTURES V GP LLC, its General Partner

 

By: MPM BIOVENTURES V LLC, its Managing Member

 

 

 

 

 

By:

/s/ Vaughn Kailian

 

Name:

Vaughn Kailian

 

Title:

Member

 

 

 

 

 

 

 

MPM ASSET MANAGEMENT INVESTORS BV5 LLC

 

By: MPM BIOVENTURES V LLC, its Manager

 

 

 

 

 

 

 

By:

/s/ Vaughn Kailian

 

Name:

Vaughn Kailian

 

Title:

Member

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES B MEMBERS:

 

 

 

 

 

New Enterprise Associates 13, L.P.

 

By: NEA Partners 13, L.P., its general partner

 

By: NEA 13 GP, LTD, its general partner

 

 

 

 

 

By:

/s/ Louis S. Citron

 

Name:

Louis S. Citron

 

Title:

Chief Legal Officer

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES B MEMBERS:

 

 

 

 

 

Third Rock Ventures, L.P.

 

By: Third Rock Ventures GP, L.P., its general partner

 

By: TRV GP, LLC, its general partner

 

 

 

 

 

By:

/s/ Louis A. Tartaglia

 

Name:

Louis A. Tartaglia

 

Title:

Partner

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES B MEMBERS:

 

 

 

 

 

PFIZER INC.

 

 

 

 

 

By:

/s/ Barbara Dalton

 

Name:

Barbara Dalton

 

Title:

Vice President, Venture Capital, Worldwide Business Development

 

[Signature Page to First Amendment to Operating Agreement]

 


 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

SERIES B MEMBERS:

 

 

 

 

 

SUTREPA SAS

 

 

 

 

 

By:

/s/ Olivier Jochem

 

Name:

Olivier Jochem

 

Title:

Chairman

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

COMMON MEMBERS:

 

 

 

 

 

MPM BIOVENTURES V, L.P.

 

By: MPM BIOVENTURES V GP LLC, its General Partner

 

By: MPM BIOVENTURES V LLC, its Managing Member

 

 

 

 

 

By:

/s/ Vaughn Kailian

 

Name:

Vaughn Kailian

 

Title:

Member

 

 

 

 

 

 

 

MPM ASSET MANAGEMENT INVESTORS BV5 LLC

 

By: MPM BIOVENTURES V LLC, its Manager

 

 

 

 

 

 

 

By:

/s/ Vaughn Kailian

 

Name:

Vaughn Kailian

 

Title:

Member

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

COMMON MEMBERS:

 

 

 

 

 

New Enterprise Associates 13, L.P.

 

By: NEA Partners 13, L.P., its general partner

 

By: NEA 13 GP, LTD, its general partner

 

 

 

 

 

By:

/s/ Louis S. Citron

 

Name:

Louis S. Citron

 

Title:

Chief Legal Officer

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

COMMON MEMBERS:

 

 

 

 

 

Third Rock Ventures, L.P.

 

By: Third Rock Ventures GP, L.P., its general partner

 

By: TRV GP, LLC, its general partner

 

 

 

 

 

By:

/s/ Louis A. Tartaglia

 

Name:

Louis A. Tartaglia

 

Title:

Partner

 

[Signature Page to First Amendment to Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

COMMON MEMBERS:

 

 

 

 

 

SUTREPA SAS

 

 

 

 

 

By:

/s/ Olivier Jochem

 

Name:

Olivier Jochem

 

Title:

Chairman

 

[Signature Page to First Amendment to the Operating Agreement]

 



 

The parties hereto have caused this AMENDMENT TO OPERATING AGREEMENT to be executed and delivered as of the date first above written.

 

 

 

COMMON MEMBERS:

 

 

 

/s/ Bart Henderson

 

Bart Henderson

 

 

 

/s/ Keith Gottesdiener

 

Keith Gottesdiener

 

[Signature Page to First Amendment to the Operating Agreement]

 



 

Schedule I

 

EXHIBIT A

 

Initial Series A Members

 

Name and Address

 

Number of Series A Preferred
Units being Issued

 

Capital Contribution

 

MPM BioVentures V, L.P.

c/o MPM Capital LLC

200 Clarendon Street, 54th floor

Boston, MA 02116

 

19,572,961

 

$

11,604,377

 

MPM Asset Management Investors BV5 LLC

c/o MPM Capital LLC

200 Clarendon Street, 54th floor

Boston, MA 02116

 

760,373

 

$

472,431

 

New Enterprise Associates 13, L.P.

c/o New Enterprise Associates

1954 Greenspring Drive, Suite 600

Timonium, MD 21093

 

20,293,333

 

$

11,999,458

 

NEA Ventures 2009, Limited Partnership

c/o New Enterprise Associates

1954 Greenspring Drive, Suite 600

Timonium, MD 21093

 

40,000

 

$

24,853

 

Third Rock Ventures, L.P.

29 Newbury Street

Boston, MA 02116

 

20,333,333

 

$

11,855,543

 

 



 

Schedule II

 

EXHIBIT B

 

Initial Series B Members

 

Name and Address

 

Number of Series B Preferred
Units Being Issued

 

Capital Contribution

 

MPM BioVentures V, L.P.

c/o MPM Capital LLC

200 Clarendon Street, 54th floor

Boston, MA 02116

 

8,811,042

 

$

4,658,906.00

 

MPM Asset Management Investors BV5 LLC

c/o MPM Capital LLC 200

Clarendon Street, 54th floor

Boston, MA 02116

 

342,292

 

$

180,990.00

 

New Enterprise Associates 13, L.P.

c/o New Enterprise Associates

1954 Greenspring Drive, Suite 600

Timonium, MD 21093

 

29,533,333

 

$

15,185,801.00

 

Third Rock Ventures, L.P.

29 Newbury Street

Boston, MA 02116

 

29,533,333

 

$

15,185,801.00

 

Pfizer Inc.

235 East 42nd Street

New York, NY 10017

Attn: Elaine V. Jones, Ph.D.

 

16,000,000

 

$

8,071,014.00

 

Sutrepa SAS

65, quai Georges Gorse,

92100 Boulogne Billancourt

Represented by Mr. Olivier Jochem,

President

 

780,000

 

$

405,215.00

 

 



 

Schedule III

 

EXHIBIT C

 

Initial Common Members

 

Name and Address

 

Capital Contribution

 

 

 

 

 

MPM BioVentures V, L.P.

c/o MPM Capital LLC

200 Clarendon Street, 54th floor

Boston, MA 02116

 

$

0

 

MPM Asset Management Investors BV5 LLC

c/o MPM Capital LLC

200 Clarendon Street, 54th floor

Boston, MA 02116

 

$

0

 

New Enterprise Associates 13, L.P.

c/o New Enterprise Associates

1954 Greenspring Drive, Suite 600

Timonium, MD 21093

 

$

0

 

Third Rock Ventures, L.P.

29 Newbury Street

Boston, MA 02116

 

$

0

 

Sutrepa SAS

65, quai Georges Gorse,

92100 Boulogne Billancourt

Represented by Mr. Olivier Jochem,

President

 

$

0

 

Michael Culler

17 Ledgestone Drive

Hopkinton, MA 01748

 

$

0

 

Bart Henderson

48 Prentiss Lane

Belmont, MA 02478

 

$

0

 

Lee Kaplan

30 Bancroft Road

Wellesley, MA 02481

 

$

0

 

Elizabeth Stoner

215 East Dudley Ave

Westfield, NJ 07090

 

$

0

 

Cathy Folster

30 Parker Avenue

Tewksbury, MA01876

 

$

0

 

Haley Laken

38 Lawrence Street

Pepperell, MA 01463

 

$

0

 

 



 

Hillori Connors

156 Salem Road

Topsfield, MA 01983

 

$

0

 

Keith Gottesdiener

900 5th Avenue, Apt. 8C

New York, NY 10021

 

$

0

 

Lex Van der Ploeg

101 Hammond Street

Newton, MA 02467

 

$

0

 

Heather Halem

24 Hyder Street

Westborough, MA 01581

 

$

0

 

Rakesh Datta

147 Brook Street, #1

Brookline, MA 02445

 

$

0

 

William Chin

25 Gray Street

Cambridge, MA 02138

 

$

0

 

John Amatruda

15 West 81st Street, Suite 15J

New York, NY 10024

 

$

0