Exhibit 99.3

MarkWest Energy Partners Announces Pricing of

$500 Million of 6.75% Senior Notes Due 2020

DENVER—October 19, 2010—MarkWest Energy Partners, L.P. (NYSE:MWE) and its subsidiary MarkWest Energy Finance Corporation announced today that they have priced at par an offering of $500,000,000 in aggregate principal amount of 6.75% senior unsecured notes due 2020 (the “Notes”).  The offering of the Notes is expected to settle on November 2, 2010, subject to customary closing conditions.

The Partnership intends to use a portion of the net proceeds from the Notes offering to purchase any and all of the outstanding $225,000,000 aggregate principal amount of its 6.875% senior notes due 2014 (CUSIP No. 570506AC9) and $150,000,000 aggregate principal amount of its 6.875% senior notes due 2014 (CUSIP No. 570506AL9) pursuant to tender offers for each series of such outstanding notes, to repay borrowings outstanding under the Partnership’s revolving credit facility, to redeem any of such outstanding notes not acquired in the tender offers, and to provide working capital for general partnership purposes.   To the extent that any of such outstanding notes are not tendered or redeemed or either of the tender offers is not consummated, the Partnership will use the remaining net proceeds to repay borrowings outstanding under the Partnership’s revolving credit facility and to provide working capital for general partnership purposes.

Wells Fargo Securities, BofA Merrill Lynch, Barclays Capital, Morgan Stanley and RBC Capital Markets are acting as joint book-running managers for the Notes offering. The Notes offering is being made only by means of a prospectus supplement and accompanying base prospectus. A copy of the prospectus supplement and accompanying base prospectus associated with this offering may be obtained from the underwriters as follows:

Wells Fargo Securities

550 South Tryon Street, 7th Floor

MAC D1086-070

Charlotte, NC 28202

Toll-Free: (800) 326-5897

cmclientsupport@wellsfargo.com

BofA Merrill Lynch

Attn: Prospectus Department

4 World Financial Center

New York, NY 10080

Email: dg.prospectus_requests@baml.com

Barclays Capital

c/o Broadridge Financial Solutions

1155 Long Island Ave.

Edgewood, NY 11717

barclaysprospectus@broadridge.com

Toll-Free: (888) 603-5847

Morgan Stanley

Attn: Prospectus Dept.

180 Varick Street, 2nd Floor

New York, NY 10014

Email: prospectus@morganstanley.com

Toll-Free: (866) 718-1649

RBC Capital Markets,

Three World Financial Center

200 Vesey Street, 9th Floor

New York, NY 10281-8098

Attention: High Yield Capital Markets

Telephone: 212-618-2205

An electronic copy of the preliminary prospectus supplement and the accompanying base prospectus is available from the Securities and Exchange Commission’s (SEC) web site at http://www.sec.gov. The Notes are being offered pursuant to an effective shelf registration statement that the Partnership previously filed with the SEC. This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these Notes in any state in which such offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of such state.

###

MarkWest Energy Partners, L.P. is a master limited partnership engaged in the gathering, transportation, and processing of natural gas; the transportation, fractionation, marketing, and storage of natural gas liquids; and the gathering and transportation of crude oil. MarkWest has extensive natural gas gathering, processing, and transmission operations in the southwest, Gulf Coast, and northeast regions of the United States, including the Marcellus Shale, and is the largest natural gas processor in the Appalachian region.

This press release includes “forward-looking statements.” All statements other than statements of historical facts included or incorporated herein may constitute forward-looking statements. Actual results could vary significantly from those expressed or implied in such statements and are subject to a number of risks and uncertainties. Although we believe that the expectations reflected in the forward-looking statements are reasonable, we can give no assurance that such expectations will prove to be correct. The forward-looking statements involve risks and uncertainties that affect our operations, financial performance, and other factors as discussed in our filings with the Securities and Exchange Commission. Among the factors that could cause results to differ materially are those risks discussed in the periodic reports we file with the SEC, including our Annual Report on Form 10-K for the year ended December 31, 2009, and our Quarterly Report on Form 10-Q for the quarter ended June 30, 2010. You are urged to carefully review and consider the cautionary statements and other disclosures made in those filings, specifically those under the heading “Risk Factors.” We do not undertake any duty to update any forward-looking statement except as required by law.