Attached files

file filename
10-K - 10-K - Celldex Therapeutics, Inc.a2196680z10-k.htm
EX-32 - EXHIBIT 32 - Celldex Therapeutics, Inc.a2196680zex-32.htm
EX-4.5 - EXHIBIT 4.5 - Celldex Therapeutics, Inc.a2196680zex-4_5.htm
EX-21.0 - EXHIBIT 21.0 - Celldex Therapeutics, Inc.a2196680zex-21_0.htm
EX-31.2 - EXHIBIT 31.2 - Celldex Therapeutics, Inc.a2196680zex-31_2.htm
EX-23.2 - EXHIBIT 23.2 - Celldex Therapeutics, Inc.a2196680zex-23_2.htm
EX-31.1 - EXHIBIT 31.1 - Celldex Therapeutics, Inc.a2196680zex-31_1.htm
EX-10.35 - EXHIBIT 10.35 - Celldex Therapeutics, Inc.a2196680zex-10_35.htm
EX-10.28 - EXHIBIT 10.28 - Celldex Therapeutics, Inc.a2196680zex-10_28.htm
EX-10.42 - EXHIBIT 10.42 - Celldex Therapeutics, Inc.a2196680zex-10_42.htm
EX-10.29 - EXHIBIT 10.29 - Celldex Therapeutics, Inc.a2196680zex-10_29.htm
EX-10.30 - EXHIBIT 10.30 - Celldex Therapeutics, Inc.a2196680zex-10_30.htm
EX-10.27 - EXHIBIT 10.27 - Celldex Therapeutics, Inc.a2196680zex-10_27.htm
EX-10.41 - EXHIBIT 10.41 - Celldex Therapeutics, Inc.a2196680zex-10_41.htm
EX-10.34 - EXHIBT 10.34 - Celldex Therapeutics, Inc.a2196680zex-10_34.htm

QuickLinks -- Click here to rapidly navigate through this document


Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

        We hereby consent to the incorporation by reference in the Registration Statements on Form S-8 (File Nos. 333-151728, 333-117602 and 333-162423) and on Form S-3 (File No. 333-143112 and 333-162613) of Celldex Therapeutics, Inc. of our report dated March 12, 2010 relating to the financial statements and the effectiveness of internal control over financial reporting, which appears in this Form 10-K.

/s/ PricewaterhouseCoopers LLP

Boston, Massachusetts
March 12, 2010




QuickLinks