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EX-99.12 - EXHIBIT 99.12 - Trillium Therapeutics Inc.tm2113451d1_ex99-12.htm
EX-99.11 - EXHIBIT 99.11 - Trillium Therapeutics Inc.tm2113451d1_ex99-11.htm
EX-99.10 - EXHIBIT 99.10 - Trillium Therapeutics Inc.tm2113451d1_ex99-10.htm
EX-99.8 - EXHIBIT 99.8 - Trillium Therapeutics Inc.tm2113451d1_ex99-8.htm
EX-99.7 - EXHIBIT 99.7 - Trillium Therapeutics Inc.tm2113451d1_ex99-7.htm
EX-99.6 - EXHIBIT 99.6 - Trillium Therapeutics Inc.tm2113451d1_ex99-6.htm
EX-99.5 - EXHIBIT 99.5 - Trillium Therapeutics Inc.tm2113451d1_ex99-5.htm
EX-99.4 - EXHIBIT 99.4 - Trillium Therapeutics Inc.tm2113451d1_ex99-4.htm
EX-99.3 - EXHIBIT 99.3 - Trillium Therapeutics Inc.tm2113451d1_ex99-3.htm
EX-99.2 - EXHIBIT 99.2 - Trillium Therapeutics Inc.tm2113451d1_ex99-2.htm
EX-99.1 - EXHIBIT 99.1 - Trillium Therapeutics Inc.tm2113451d1_ex99-1.htm
8-K - FORM 8-K - Trillium Therapeutics Inc.tm2113451d1_8k.htm

Exhibit 99.9

 

NOTICE TO READER

 

As of June 30, 2020, the last business day of the second quarter of Trillium Therapeutics Inc. (the “Company”), the Company determined that it no longer qualified as a “foreign private issuer” as such term is defined in Rule 405 under the United States Securities Act of 1933, as amended. As a result, effective January 1, 2021, the Company has been required to comply with all of the periodic disclosure requirements of the United States Securities Exchange Act of 1934, as amended, applicable to U.S. domestic issuers, such as Forms 10-K, 10-Q and 8-K, rather than the forms the Company has filed with the Securities and Exchange Commission (“SEC”) in the past as a foreign private issuer, such as Forms 40-F and 6-K, among other requirements.

 

Accordingly, the Company is now required to prepare its financial statements filed with the SEC in accordance with generally accepted accounting principles in the United States (“U.S. GAAP”). As required pursuant to section 4.3(4) of Ontario Securities Commission National Instrument 51-102 – Continuous Disclosure Obligations, the Company must restate its interim financial reports for the fiscal year ended December 31, 2020 in accordance with U.S. GAAP as such interim financial reports having previously been prepared in accordance with International Financial Reporting Standards as issued by the International Accounting Standards Board.

 

The attached amended and restated interim condensed consolidated financial statements (the “Financial Statements”) for the three and nine months ended September 30, 2020 and 2019 have been prepared in accordance with U.S. GAAP, are current as of November 17, 2020 and provide financial information for the three and nine months ended September 30, 2020, as amended and restated on April 23, 2021. Other than as expressly set forth above, the revised Financial Statements do not, and do not purport to, update or restate the information in the original condensed interim consolidated financial statements or reflect any events that occurred after the date of the filing of the original condensed interim consolidated financial statements.

 

The Company’s Annual Report on Form 10-K (the “Annual Report”) dated March 18, 2021 is available under the Company’s profile on SEDAR at www.sedar.com and on EDGAR at www.sec.gov. Readers are cautioned that these Financial Statements should be read in conjunction with the Annual Report, including the audited consolidated financial statements and the related notes thereto included in Item 8 thereof.

 

 

 

INTERIM CONDENSED

CONSOLIDATED FINANCIAL STATEMENTS

 

FOR THE THREE AND NINE MONTHS ENDED

SEPTEMBER 30, 2020 AND 2019

 

(UNAUDITED)

 

2488 Dunwin Drive

Mississauga, Ontario L5L 1J9

www.trilliumtherapeutics.com

 

 

TRILLIUM THERAPEUTICS INC.

Condensed Consolidated Balance Sheets

Amounts in thousands of US dollars, except share data (unaudited)

 

 

   September 30, 2020   December 31, 2019 
   $   $ 
ASSETS          
Current          
Cash and cash equivalents  237,260    14,584 
Marketable securities   55,149    8,082 
Amounts receivable   1,032    327 
Prepaid expenses   2,836    299 
           
Total current assets   296,277    23,292 
Property and equipment, net   926    1,369 
Intangible assets   783    783 
Operating lease right-of-use assets   790    949 
           
Total non-current assets   2,499    3,101 
           
Total assets   298,776    26,393 
           
LIABILITIES          
Current          
Accounts payable   3,556    1,592 
Accrued expenses   9,412    11,729 
Current portion of operating lease liabilities   232    208 
Stock option liability   12,131    - 
Warrant liability   -    13,370 
           
Total current liabilities   25,331    26,899 
           
Operating lease liabilities, net of current portion   635    827 
           
Total non-current liabilities   635    827 
           
Total liabilities   25,966    27,726 
           
Commitments and Contingencies (Note 10)          
           
STOCKHOLDERS’ EQUITY (DEFICIT)          
Series I preferred shares, without par value: unlimited shares authorized; No shares and 17,171,541 shares issued and outstanding at September 30, 2020 and December 31, 2019, respectively   -    2,348 
Series II preferred shares, without par value: unlimited shares authorized; 6,750,000 and 8,868,403 shares issued and outstanding at September 30, 2020 and December 31, 2019, respectively   15,698    21,485 
Common shares, without par value: unlimited shares authorized; 100,356,505 and 28,938,831 shares issued and outstanding at September 30, 2020 and December 31, 2019, respectively   459,504    149,393 
Warrants   5,293    - 
Additional paid-in capital   41,969    23,072 
Accumulated other comprehensive loss   (7,602)   (7,602)
Accumulated deficit   (242,052)   (190,029)
           
Total stockholders’ equity (deficit)   272,810    (1,333)
           
Total liabilities and stockholders’ equity (deficit)   298,776    26,393 

 

The accompanying notes are an integral part of these condensed consolidated financial statements. 

- 1 -

 

TRILLIUM THERAPEUTICS INC.

Condensed Consolidated Statements of Operations and Comprehensive Loss

Amounts in thousands of US dollars, except share and per share data (unaudited)

 

 

   Three months ended
September 30, 2020
   Three months ended
September 30, 2019
   Nine months ended
September 30, 2020
   Nine months ended
September 30, 2019
 
   $   $   $   $ 
REVENUE   -    99    115    124 
                     
OPERATING EXPENSES                    
Research and development   7,476    6,040    19,638    21,384 
General and administrative   5,518    926    33,890    2,597 
                     
Total operating expenses   12,994    6,966    53,528    23,981 
                     
Operating loss   (12,994)   (6,867)   (53,413)   (23,857)
                     
Other income (expense)                    
Interest income, net   483    156    1,336    482 
Net foreign currency gain (loss)   13    176    114    (619)
Revaluation of warrant liability, net   -    498    -    5,051 
                     
Total other income, net   496    830    1,450    4,914 
                     
Net loss before income taxes   (12,498)   (6,037)   (51,963)   (18,943)
                     
Income tax expense   9    13    60    24 
                     
Net loss   (12,507)   (6,050)   (52,023)   (18,967)
                     
Other comprehensive income                    
Foreign currency translation adjustments   -    (170)   -    441 
                     
Total other comprehensive income (loss)   -    (170)   -    441 
                     
Comprehensive loss   (12,507)   (6,220)   (52,023)   (18,526)
                     
Net loss per share, basic and diluted   (0.14)   (0.22)   (0.66)   (0.78)
                     
Weighted average number of common shares used in computing net loss per share, basic and diluted   87,832,810    28,038,831    79,063,476    24,214,106 

 

The accompanying notes are an integral part of these condensed consolidated financial statements.

- 2 -

 

TRILLIUM THERAPEUTICS INC.

Condensed Consolidated Statements of Stockholders’ Equity (Deficit)

Amounts in thousands of US dollars, except share data (unaudited)

 

 

   Common shares  Series I preferred
shares
  Series II preferred
shares
  Warrants  Additional
paid-in capital
  Accumulated other comprehensive loss  Deficit  Total 
   #  $  #  $  #  $  #  $  $  $  $  $ 
Balance at December 31, 2019   28,938,831   149,393   17,171,541   2,348   8,868,403   21,485   -   -   23,072   (7,602)  (190,029)  (1,333)
Issuance of preferred and common shares, net of issue costs   41,279,090   106,515   -   -   1,250,000   3,225   -   -   -   -   -   109,740 
Reclassification of warrants from liability to equity   -   -   -   -   -   -   18,750,000   13,370   -   -   -   13,370 
Reclassification of stock options from equity to liability   -   -   -   -   -   -   -   -   (225)  -   -   (225)
Exercise of options   340,000   1,859   -   -   -   -   -   -   (781)  -   -   1,078 
Exercise of warrants   7,684,717   12,858   -   -   1,750,000   2,928   (9,434,717)  (6,727)  -   -   -   9,059 
Conversion of preferred shares into common shares   4,440,787   11,387   (17,171,541)  (2,348)  (3,868,403)  (9,039)  -   -   -   -   -   - 
Stock-based compensation   -   -   -   -   -   -   -   -   252   -   -   252 
Net loss   -   -   -   -   -   -   -   -   -   -   (16,298)  (16,298)
Balance at March 31, 2020   82,683,425   282,012   -   -   8,000,000   18,599   9,315,283   6,643   22,318   (7,602)  (206,327)  115,643 
Change from cash to equity settlement of deferred share units (“DSUs”)   -   -   -   -   -   -   -   -   24,948   -   -   24,948 
Exercise of options   4,947   26   -   -   -   -   -   -   (9)  -   -   17 
Exercise of warrants   1,892,099   3,166   -   -   -   -   (1,892,099)  (1,350)  -   -   -   1,816 
Stock-based compensation   -   -   -   -   -   -   -   -   218   -   -   218 
Net loss   -   -   -   -   -   -   -   -   -   -   (23,218)  (23,218)
Balance at June 30, 2020   84,580,471   285,204   -   -   8,000,000   18,599   7,423,184   5,293   47,475   (7,602)  (229,545)  119,424 
Issuance of common shares, net of issue costs   13,797,794   165,311   -   -   -   -   -   -   -   -   -   165,311 
Shares issued upon redemption of DSUs   667,888   5,422   -   -   -   -   -   -   (5,422)  -   -   - 
Exercise of options   60,352   666   -   -   -   -   -   -   (284)  -   -   382 
Conversion of preferred shares into common shares   1,250,000   2,901   -   -   (1,250,000)  (2,901)  -   -   -   -   -   - 
Stock-based compensation   -   -   -   -   -   -   -   -   200   -   -   200 
Net loss   -   -   -   -   -   -   -   -   -   -   (12,507)  (12,507)
Balance at September 30, 2020   100,356,505   459,504   -   -   6,750,000   15,698   7,423,184   5,293   41,969   (7,602)  (242,052)  272,810 

 

   Common shares  Series I preferred
shares
  Series II preferred
shares
  Warrants  Additional
paid-in capital
  Accumulated other comprehensive loss  Deficit  Total 
   #  $  #  $  #  $  #  $  $  $  $  $ 
Balance at December 31, 2018   14,688,831   129,513   17,171,541   2,348   4,368,403   35,235   -   -   20,555   (8,016)  (152,053)  27,582 
Adoption of ASU 2016-02   -   -   -   -   -   -   -   -   -   -   106   106 
Units issued, net of issue costs   6,550,000   2,131   -   -   12,200,000   3,999   -   -   -   -   -   6,130 
Conversion of preferred shares into common shares   5,050,000   11,641   -   -   (5,050,000)  (11,641)  -   -   -   -   -   - 
Stock-based compensation   -   -   -   -   -   -   -   -   604   -   -   604 
Foreign currency translation adjustments   -   -   -   -   -   -   -   -   -   260   -   260 
Net loss   -   -   -   -   -   -   -   -   -   -   (7,734)  (7,734)
Balance, March 31, 2019   26,288,831   143,285   17,171,541   2,348   11,518,403   27,593   -   -   21,159   (7,756)  (159,681)  26,948 
Conversion of preferred shares into common shares   1,750,000   4,035   -   -   (1,750,000)  (4,035)  -   -   -   -   -   - 
Stock-based compensation   -   -   -   -   -   -   -   -   1,117   -   -   1,117 
Foreign currency translation adjustments   -   -   -   -   -   -   -   -   -   351   -   351 
Net loss   -   -   -   -   -   -   -   -   -   -   (5,183)  (5,183)
Balance, June 30, 2019   28,038,831   147,320   17,171,541   2,348   9,768,403   23,558   -   -   22,276   (7,405)  (164,864)  23,233 
Stock-based compensation   -   -   -   -   -   -   -   -   398   -   -   398 
Foreign currency translation adjustments   -   -   -   -   -   -   -   -   -   (170)  -   (170)
Net loss   -   -   -   -   -   -   -   -   -   -   (6,050)  (6,050)
Balance, September 30, 2019   28,038,831   147,320   17,171,541   2,348   9,768,403   23,558   -   -   22,674   (7,575)  (170,914)  17,411 

 

The accompanying notes are an integral part of these condensed consolidated financial statements.

- 3 -

 

TRILLIUM THERAPEUTICS INC.

Condensed Consolidated Statements of Cash Flows

Amounts in thousands of US dollars, except share data (unaudited)

 

 

   Nine months ended
September 30, 2020
   Nine months ended
September 30, 2019
 
   $   $ 
Cash flows from operating activities          
Net loss   (52,023)   (18,967)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities          
Interest accretion   -    5 
Stock-based compensation   35,151    1,897 
Remeasurement of warrant liability   -    (5,577)
Depreciation of property and equipment   443    440 
Unrealized foreign exchange loss (gain)   (160)   343 
    (16,589)   (21,859)
Changes in operating assets and liabilities          
Amounts receivable   (705)   363 
Prepaid expenses   (2,537)   328 
Operating lease right of use asset   159    113 
Accounts payable   1,964    895 
Accrued expenses   58    (4)
Operating lease liability   (168)   (143)
Other current liabilities   -    (418)
           
Net cash used in operating activities   (17,818)   (20,725)
           
Cash flows from investing activities          
Maturities of marketable securities   18,425    62,236 
Purchases of marketable securities   (65,430)   (58,929)
Purchases of property and equipment   -    (228)
           
Net cash provided by (used in) investing activities   (47,005)   3,079 
           
Cash flows from financing activities          
Exercise of stock options   1,477    - 
Exercise of warrants   10,875    - 
Issuance of warrants, net of issuance costs   -    7,717 
Issuance of preferred and common shares, net of issuance costs   275,051    6,166 
           
Net cash provided by financing activities   287,403    13,883 
           
Impact of foreign exchange rate on cash and cash equivalents   96    799 
           
Net increase (decrease) in cash and cash equivalents   222,676    (2,964)
           
Cash and cash equivalents, beginning of period   14,584    15,318 
           
Cash and cash equivalents, end of period   237,260    12,354 
           
Supplemental cash flow disclosures          
Operating lease right-of-use assets obtained in exchange for operating lease liabilities   -    1,097 
Cash paid for operating lease payments   256    247 
Cash paid for income taxes   23    11 
Reclassification of warrants from liability to equity   13,370    - 
Reclassification of stock options from equity to liability   225    - 
Reclassification of DSUs from liability to equity   24,948    - 

 

The accompanying notes are an integral part of these condensed consolidated financial statements.

- 4 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

1.Description of the business

 

Trillium Therapeutics Inc. (the “Company” or “Trillium”) is a clinical-stage immuno-oncology company developing innovative therapies for the treatment of cancer. The Company’s two clinical programs, TTI-621 and TTI-622, target CD47, a “don’t eat me” signal that cancer cells frequently use to evade the immune system. The Company is a corporation existing under the laws of the Province of British Columbia.

 

Since inception, the Company has been primarily involved in research and development activities and has incurred significant net losses. As of September 30, 2020, the Company had an accumulated deficit of $242.1 million. The Company anticipates that it will continue to incur significant expenses and operating losses for the foreseeable future as it continues to develop its product candidates. As a result, the Company will require substantial additional capital to fund its continued operations and pursue its growth strategy. The Company has not generated any product revenues and has financed its operations primarily through public offerings of its equity securities. There can be no assurance that the Company will be able to raise additional funds or enter into such other agreements on favorable terms, or at all. The failure of the Company to obtain sufficient funds on acceptable terms when needed could have a material adverse effect on the Company’s business, results of operations, and financial condition.

 

As of September 30, 2020, the Company had cash and cash equivalents and marketable securities of $292.4 million. The Company believes that its existing cash and cash equivalents and marketable securities will enable it to fund its expected operating requirements for at least 12 months following the issuance of these condensed consolidated financial statements.

 

The Company is subject to a number of risks similar to other biopharmaceutical companies in the early stage, including, but not limited to, the need to obtain adequate additional funding, possible failure of preclinical testing or clinical trials, the need to obtain marketing approval for its product candidates, competitors developing new technological innovations, the need to successfully commercialize and gain market acceptance of the Company’s products, and protection of proprietary technology. If the Company does not successfully obtain regulatory approval, commercialize or partner any of its product candidates, it will be unable to generate revenue from product sales or achieve profitability.

 

2.Summary of significant accounting policies

 

(a)Basis of presentation and consolidation

 

These accompanying unaudited condensed consolidated financial statements, including comparatives, have been prepared in accordance with US generally accepted accounting principles (“GAAP”) for interim reporting and as required by Regulation S-X, Rule 10-01. Accordingly, they do not include all of the information and footnotes required by GAAP for complete financial statements. These interim condensed consolidated financial statements, in the opinion of management, reflect all normal recurring adjustments necessary for a fair presentation of the Company’s financial position and results of operations for the periods presented. See “Recently Adopted Accounting Pronouncements” below for discussion of the Company’s adoption of new guidance effective January 1, 2020.

 

These condensed consolidated financial statements include the accounts of the Company and its wholly owned subsidiary, Trillium Therapeutics USA Inc. The financial statements of the subsidiaries are prepared for the same reporting period as the Company using consistent accounting policies. Intercompany transactions, balances and gains and losses on transactions between the Company and the subsidiaries are eliminated.

 

The Company’s significant accounting policies are disclosed in the audited consolidated financial statements for the years ended December 31, 2020 and 2019 and included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2020 as filed with the Securities and Exchange Commission (“SEC”) on March 18, 2021.

 

(b)Functional and presentation currency

 

These unaudited condensed consolidated financial statements are presented in US dollars, which is the Company’s functional currency. On January 1, 2020, the Company’s functional currency was changed to US dollars from Canadian dollars. The change was made to reflect that US dollars has become the currency of the primary economic environment in which the Company operates, accounting for a significant part of the Company’s labour, clinical operations, and financing. The change has been implemented prospectively.

 

(c)Use of estimates

 

The preparation of consolidated financial statements in conformity with GAAP requires management to make estimates and assumptions that affect the application of accounting policies and the reported amounts of assets and liabilities at the date of the consolidated financial statements, reported amounts of revenue and expenses during the reporting periods, and related disclosures in the accompany notes. Significant estimates and assumptions reflected in these consolidated financial statements include, but are not limited to, accrued clinical and contract research organization costs, stock-based compensation expense and valuation of warrant liability. The Company reviews its estimates and underlying assumptions on an ongoing basis. Revisions are recognized in the period in which the estimates are revised and may impact future periods. Actual results could differ materially from these estimates and assumptions.

- 5 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

2.Summary of significant accounting policies (continued)

 

COVID-19

 

Given the ongoing and dynamic nature of the circumstances surrounding the COVID-19 pandemic, it is difficult to predict how significant the impact of COVID-19, including any responses to it, will be on the global economy and the business of the Company or for how long any disruptions are likely to continue. The extent of such impact will depend on future developments, which are highly uncertain, rapidly evolving and difficult to predict, including new information which may emerge about COVID-19 and additional actions which may be taken to contain it. Such developments could have a material adverse effect on the Company’s business, financial condition, results of operations and cash flow, and exposure to credit risk. The Company is constantly evaluating the situation and monitoring any impacts or potential impacts to its business.

 

(d)Adopted and recent accounting pronouncements

 

Accounting pronouncement adopted on January 1, 2020

 

The Company adopted ASU No. 2018-13 Fair Value Measurement (Topic 820) on January 1, 2020. The amendments in this ASU modify the disclosure requirements on fair value measurements in ASC 820 Fair Value Measurement. Various disclosure requirements have been removed, including the amount of and reasons for transfers between Level 1 and Level 2 of the fair value hierarchy, the policy for timing of transfers between levels, and the valuation processes for Level 3 fair value measurements held at the end of the reporting period. The ASU also modified various disclosure requirements and added some disclosure requirements for Level 3 fair value measurements. The adoption of the new accounting standard did not have a material impact on the Company’s consolidated financial statements.

 

Recent accounting pronouncements

 

In June 2016, the FASB issued ASU No. 2016-13 Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments. The new standard changes the impairment model for most financial assets and certain other instruments. Under the new standard, entities holding financial assets and net investment in leases that are not accounted for at fair value through net income are to present them at the net amount expected to be collected. An allowance for credit losses will be a valuation account that will be deducted from the amortized cost basis of the financial asset to present the net carrying value at the amount expected to be collected on the financial asset. The Company has determined that the adoption of this standard will not have a material impact on the consolidated financial statements.

 

3.Fair value measurements

 

Assets and liabilities measured at fair value on a recurring basis as of September 30, 2020 and December 31, 2019 are as follows (in thousands):

 

  

Total

$

  

Quoted prices in
active markets

(Level 1)

$

  

Significant other
observable inputs
 

(Level 2) 

$

  

Significant
unobservable inputs

(Level 3)

$

 
September 30, 2020                    
Stock option liability   12,131    -    -    12,131 
Total liabilities   12,131    -    -    12,131 
                     
December 31, 2019                    
Assets                    
Cash and cash equivalents                    
Guaranteed investment certificates   7,000    7,000    -    - 
Total assets   7,000    7,000    -    - 
Liabilities                    
Warrant liability   13,370    -    -    13,370 
Total liabilities   13,370    -    -    13,370 

 

There were no changes in valuation techniques or transfers between Levels 1, 2 or 3 during the nine months ended September 30, 2020. The Company’s stock option liability is measured at fair value on a recurring basis using unobservable inputs that are classified as Level 3 inputs.

 

As of January 1, 2020, as a result of the Company’s change in functional currency to US dollars, the warrant liability was reclassified to equity. Accordingly $13.4 million was transferred from warrant liability to equity.

- 6 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

3.Fair value measurements (continued)

 

In addition, as a result of the change in functional currency, stock options issued to Canadian employees are continued to be classified as equity, and stock options issued to US employees under the 2018 Stock Option Plan and the 2019 Inducement Plan are to be classified as a stock option liability as they have exercise prices denominated in Canadian dollars. The change in functional currency was treated as a stock option modification and accordingly $0.2 million was reclassified from additional paid-in capital to stock option liability on January 1, 2020. For each reporting period after the modification date, the stock option liability is adjusted so that it equals the portion of the requisite service provided multiplied by the modified award’s fair value at the end of the reporting period.

 

As of September 30, 2020 and December 31, 2019, the balances of the stock option liability were $12.1 million and $0, respectively. The change in fair value of the stock option liability for the nine months ended September 30, 2020 was as follows (in thousands):

  

   September 30, 2020 
   $ 
Beginning balance   - 
Reclassification to stock option liability due to change in functional currency   225 
Change in fair value of stock option liability   11,906 
Ending balance   12,131 

 

The change in fair value of stock option liability is recorded as stock-based compensation expense in the statements of operations and comprehensive loss. For the three and nine months ended September 30, 2020, $2.6 million and $4.7 million of change in fair value of stock option liability was included in research and development expenses, respectively, and $4.2 million and $7.2 million was included in general and administrative expenses, respectively.

 

The equity-settled stock option liability was determined based on the fair value of the liability at the reporting date using the Black-Scholes model with the following weighted average assumptions:

 

   September 30, 2020 
Expected option life  4.9 years 
Risk-free interest rate   0.3%
Dividend yield   0%
Expected volatility   114%

 

The Black-Scholes option pricing model requires subjective assumptions, including expected volatility and average option life.

 

The expected volatility is based on the Company’s historical stock price volatility. The expected life of the options is estimated considering the vesting period at the grant date, the life of the option and the average length of time similar grants have remained outstanding in the past. The risk-free interest rate is based on the implied yield on a US Government bond with a remaining term equal to the expected term of the option. The dividend yield was excluded from the calculation since it is the present policy of the Company to retain all earnings to finance operations and future growth.

 

4.Leases

 

On January 1, 2019, the date of adoption of ASC 842, the Company had an existing operating lease (the “2015 Lease”), to lease 22,003 square feet of a Mississauga, Ontario facility. The term of the 2015 Lease commenced on November 1, 2015. The 2015 Lease has an initial term of 10 years from the commencement date, and the Company has an option to extend the initial term for two further terms of five years each. The Company had the option to terminate the lease agreement any time after 5 years (i.e. after October 31, 2020) with a minimum of 9 months prior written notice. If the Company terminates the lease agreement between the 61st to the 84th month, the Company is obligated to pay the unamortized balance of tenant improvement allowance based on a rate of 8%, plus 4 months minimum rent and additional rent. Upon early termination after the 84th month, the Company is obligated to pay the unamortized balance of tenant improvement allowance based on a rate of 8%, plus 2 months minimum rent and additional rent. As part of the determination of its right-of-use assets, the Company assumed that it would terminate this lease at the end of the 84th month. The landlord agreed to pay the Company a lease inducement for the 2015 Lease of $0.2 million to reimburse the Company for leasehold improvements being made to the leased premises and the acquisition of certain equipment.

 

On April 1, 2019, the Company entered into an operating lease (the “2019 Lease”) to lease approximately 3,200 of square feet of office space located in Cambridge, Massachusetts. The 2019 Lease has an initial term of 5 years from the commencement date with no option to extend the initial term. The annual base rent increases on an annual basis from the 13th month to approximately $0.2 million for the fifth year of the lease. The landlord agreed to pay the Company a lease inducement of $0.1 million to reimburse the Company for leasehold improvements being made to the leased premises.

- 7 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

4.Leases (continued)

 

Future minimum lease payments under non-cancellable lease agreements as of September 30, 2020 were as follows (in thousands):

  

   September 30, 2020 
   $ 
2020   90 
2021   334 
2022   438 
2023   184 
2024   46 
2025 and beyond   - 
Total minimum lease payments   1,092 
Less: Imputed interest   (225)
Present value of lease liabilities   867 

 

Lease expense is recognized on a straight-line basis over the term of the leases and accordingly the Company records the difference between cash rent payments and the recognition of lease expense against the operating lease right-of-use asset. For the three and nine months ended September 30, 2020, variable lease payments relating to the Company’s operating leases were $39 thousand and $0.1 million, respectively (2019 - $30 thousand and $0.1 million, respectively). Lease expenses during the three and nine months ended September 30, 2020 were $0.1 million and $0.3 million, respectively (2019 - $0.1 million and $0.2 million, respectively). As of September 30, 2020, the weighted average remaining lease term was 2.7 years and the weighted average incremental borrowing rate used to determine the operating lease liability was 15%.

 

5.Accrued expenses

 

The Company’s accrued expenses consisted of the following as of September 30, 2020 and December 31, 2019 (in thousands):

  

   September 30, 2020   December 31, 2019 
   $   $ 
Accrued employee compensation   779    1,474 
Accrued clinical and contract research organization costs   7,045    6,765 
Other accrued expenses   1,174    715 
Amounts due to related parties   414    2,775 
Total   9,412    11,729 

 

In the prior year, amounts due to related parties included cash-settled DSUs.

 

6.Stockholder’s equity

 

(a)Authorized

 

The authorized share capital of the Company consists of an unlimited number of common shares, Class B shares and First Preferred Shares, in each case without nominal or par value. Common shares are voting and may receive dividends as declared at the discretion of the Board of Directors. Class B shares are non-voting and convertible to common shares at the holder’s discretion, on a one-for-one basis. Upon dissolution or wind-up of the Company, Class B shares participate rateably with the common shares in the distribution of the Company’s assets. First Preferred Shares have voting rights as decided upon by the Board of Directors at the time of grant. Upon dissolution or wind-up of the Company, First Preferred Shares are entitled to priority over common shares and Class B shares.

 

The Company has Series I First Preferred Shares that are non-voting, may receive dividends as declared at the discretion of the Board of Directors, and are convertible to common shares at the holder’s discretion, on the basis of 30 Series I First Preferred Shares for one common share.

 

The Company has Series II First Preferred Shares that are non-voting, may receive dividends as declared at the discretion of the Board of Directors, and are convertible to common shares at the holder’s discretion, on the basis of one Series II First Preferred Share for one common share.

 

Holders may not convert Series I or Series II First Preferred Shares into common shares if, after giving effect to the exercise of conversion, the holder would have beneficial ownership or direction or control over common shares in excess of 4.99% of the then outstanding common shares. This limit may be raised at the option of the holder on 61 days’ prior written notice: (i) up to 9.99%, (ii) up to 19.99%, subject to clearance of a personal information form submitted by the holder to the Toronto Stock Exchange and (iii) above 19.99%, subject to approval by the Toronto Stock Exchange and stockholder approval.

- 8 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

6.Stockholder’s equity (continued)

 

(b)Shares issued – nine months ended September 30, 2020

 

In January 2020, the Company completed an underwritten public offering of 41,279,090 common shares and 1,250,000 Series II Non-Voting Convertible First Preferred Shares, each issued at $2.75 per share. The number of shares sold include 5,547,272 common shares pursuant to the full exercise by the underwriters of their option to purchase additional common shares. The gross proceeds from this offering were $117.0 million before deducting offering expenses of $7.2 million.

 

In September 2020, the Company issued 2,297,794 common shares at a price of $10.88 per share to Pfizer Inc. in a registered direct offering. The gross proceeds from this offering were $25.0 million, before deducting offering expenses of $0.1 million.

 

In September 2020, the Company also completed an underwritten public offering of 11,500,000 common shares, issued at $13.00 per share. The number of shares sold include 1,500,000 common shares pursuant to the full exercise by the underwriters of their option to purchase additional common shares. The gross proceeds from this offering were $149.5 million, before deducting offering expenses of $9.1 million.

 

During the nine months ended September 30, 2020, 9,576,816 common shares were issued on the exercise of 9,576,816 common share purchase warrants for proceeds of $9.2 million, and 1,750,000 Series II First Preferred Shares were issued on the exercise of 1,750,000 Series II First Preferred Share purchase warrants for proceeds of $1.7 million.

 

During the nine months ended September 30, 2020, 17,171,541 Series I First Preferred Shares were converted into 572,384 common shares, and 5,118,403 Series II First Preferred Shares were converted into 5,118,403 common shares.

 

7.Net loss per share

 

Basic net loss per share is calculated by dividing net loss by the weighted average shares outstanding during the period, without consideration for common share equivalents. Diluted net loss per share is calculated by adjusting weighted average shares outstanding for the dilutive effect of common share equivalents outstanding for the period. For purposes of the dilutive net loss per share calculation, preferred shares, warrants, stock options, and deferred share units are considered to be common share equivalents but are excluded from the calculation of diluted net loss per share, as their effect would be anti-dilutive; therefore, basic and diluted net loss per share were the same for all periods presented as a result of the Company’s net loss.

 

The following common share equivalents were excluded from the computation of diluted net loss per share for the periods presented because including them would have had an anti-dilutive effect:

 

   September 30,   September 30, 
   2020   2019 
Series I First Preferred Shares   -    572,385 
Series II First Preferred Shares   6,750,000    9,768,403 
Common warrants   2,023,184    11,600,000 
Preferred warrants   5,400,000    7,150,000 
Stock options   5,051,189    4,331,026 
Deferred share units (equity-settled)   2,405,407    - 
    21,629,780    33,421,814 

 

8.Stock-based compensation

 

(a)Stock option plans

 

2020 Omnibus Plan

 

The 2020 Omnibus Equity Incentive Plan (“Omnibus Plan”) was adopted by the Board of Directors on May 6, 2020 and approved by the stockholders at the annual general and special meeting of stockholders held on June 30, 2020. Under the Omnibus Plan, the Company may grant non-statutory and incentive stock options, share appreciation rights, restricted share units, restricted share awards, unrestricted share awards, deferred share units and dividend equivalent rights. The maximum number of common shares issuable under the Omnibus Plan is 13,400,000 common shares. The Omnibus Plan replaces the 2018 Stock Option Plan, the 2016 Cash-Settled DSU Plan and the 2019 Inducement Stock Option Plan (the “Predecessor Plans”) as of July 1, 2020. As of September 30, 2020, the Company was entitled to issue an additional 10,153,205 common shares under the Omnibus Plan.

 

From July 1, 2020 to September 30, 2020, the Company granted 173,500 stock options with a weighted average exercise price of $12.51 per share. The total fair value of stock options granted from July 1, 2020 to September 30, 2020 was $1.8 million and the weighted average grant date fair value was $10.21 per share.

- 9 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

8.Stock-based compensation (continued)

 

2019 Inducement Stock Option Plan

 

Stock options of the Corporation that were granted and are outstanding under the 2019 Inducement Stock Option Plan (“2019 Inducement Plan”) will remain subject to the terms and conditions of the 2019 Inducement Plan; however, no new stock options of the Corporation will be granted under the 2019 Inducement Plan. For the nine months ended September 30, 2020 no options were granted under the 2019 Inducement Plan. As of September 30, 2020 there were 1,800,000 stock options outstanding under the 2019 Inducement Plan.

 

2018 Stock Option Plan

 

Stock options that were granted and are outstanding under the 2018 Stock Option Plan (“2018 Plan”) will remain subject to the terms and conditions of the 2018 Plan; however, no new stock options of the Corporation will be granted under the 2018 Plan after June 30, 2020. As of September 30, 2020, there were 3,077,689 stock options outstanding under the 2018 Plan.

 

Valuation and stock-based compensation expense

 

Total stock-based compensation expense recorded related to stock options granted to employees and non-employees for the three months ended September 30 were as follows (in thousands):

 

   2020   2019 
   $   $ 
Research and development   2,729    318 
General and administrative   4,294    84 
Total stock-based compensation expense   7,023    402 

 

Total stock-based compensation expense recorded related to stock options granted to employees and non-employees for the nine months ended September 30 were as follows (in thousands):

 

   2020   2019 
   $   $ 
Research and development   5,164    1,877 
General and administrative   7,412    242 
Total stock-based compensation expense   12,576    2,119 

 

Stock-based compensation expense for employees for three and nine months ended September 30, 2020 were $7.0 million and $12.5 million, respectively (2019 – an expense of $0.4 million and $2.1 million, respectively). Of the total stock-based compensation expense for employees for the three and nine months ended September 30, 2020, $6.8 million and $11.9 million related to stock options accounted for as liability awards, respectively (2019 – and expense of $0 and $0, respectively).

 

Stock-based compensation expense for non-employees for three and nine months ended September 30, 2020 were $40 thousand and $40 thousand, respectively (2019 – an expense of $0 and $0, respectively).

 

As of September 30, 2020, there was $29.7 million of unrecognized compensation expense related to unvested stock options that is expected to be recognized over a weighted average period of 2.2 years.

 

Stock option activity during the nine months ended September 30, 2020 was as follows:

 

    Number of 
options
   Weighted
average
exercise price
   Weighted
average
remaining
contractual life
(in years)
   Aggregate
intrinsic
value (in
thousands)
 
Outstanding at December 31, 2019     5,366,645   $2.44    9.0    2,246 
Granted    180,500   $12.20           
Exercised    (405,299)  $3.74           
Forfeited    (60,074)  $3.19           
Cancelled/expired    (30,583)  $14.52           
Outstanding at September 30, 2020    5,051,189   $2.60    7.4    58,876 
Exercisable at September 30, 2020     1,415,404   $5.68    6.0    12,275 

- 10 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

8.Stock-based compensation (continued)

 

Stock-based compensation expense was determined based on the fair value of the options at the date of measurement using the Black-Scholes option pricing model with the weighted average assumptions for the nine months ended September 30 as follows:

 

   2020   2019 
Expected option life  5.8 years   6.0 years 
Risk-free interest rate   0.4%   1.3%
Dividend yield   0%   0%
Expected volatility   110%   88%

 

The Black-Scholes option pricing model requires subjective assumptions, including expected volatility and average option life.

 

The expected volatility is based on the Company’s historical stock price volatility. The expected life of the options is estimated considering the vesting period at the grant date, the life of the option and the average length of time similar grants have remained outstanding in the past. The risk-free interest rate at September 30, 2020 is based on the implied yield on a US Government bond with a remaining term equal to the expected term of the option. The risk-free interest rate at September 30, 2019 is based on the implied yield on a Government of Canada zero-coupon issue with a remaining term equal to the expected term of the option. The dividend yield was excluded from the calculation since it is the present policy of the Company to retain all earnings to finance operations and future growth.

 

(b)Deferred share units

 

2016 Cash-Settled DSU Plan

 

As noted above, the Board of Directors approved the Omnibus Plan, which was approved by the stockholders on June 30, 2020. The Omnibus Plan will govern the terms of the Company’s stock option and DSU grants, and provides for equity settlement of DSUs issued for director compensation.

 

In conjunction with the approval of the Omnibus Plan, each director holding DSUs under the Cash-Settled DSU Plan entered into an agreement with the Company to have their existing DSUs be governed by the Omnibus Plan. No new DSUs will be granted under the 2016 Cash-Settled DSU Plan.

 

The Omnibus Plan provides for equity or cash settlement of DSUs issued for director compensation, at the option of the Company. It is the Company’s intention to settle all DSUs by equity. The ratification of the Omnibus Plan on June 30, 2020, which now provides for equity settlement of DSUs issued for director compensation, was treated as a modification under ASC 718 Compensation – Stock Compensation and the Company’s DSUs were classified as equity instead of as a liability. Accordingly, as of June 30, 2020, $24.9 million was transferred from a liability to equity.

 

For the nine months ended September 30, 2020 and 2019, there were 27,474 and 807,261 DSUs issued, respectively. For the three and nine months ended September 30, 2020, the DSU expense, comprised of directors’ fees paid and the revaluation of the DSU liability up to June 30, 2020 prior to the transfer to equity, were $0.1 million and $22.5 million, respectively (2019 – an expense of $0.2 million and $0.2 million, respectively). The number of DSUs outstanding as of September 30, 2020 and December 31, 2019 were 2,405,407 and 3,045,821, respectively. For the nine months ended September 30, 2020 and 2019, 667,888 and no DSUs were redeemed, respectively.

 

9.License agreements

 

In June 2020, the Company entered into a right-to-use license agreement for one of its small molecule compounds, with initial license fees of $0.1 million. Sales-based royalties, anniversary payments and milestone payments will be recognized when earned in future periods.

 

For the three and nine months ended September 30, 2020, the Company recognized licensing revenues consisting of initial license fees and license extension fees of $0 and $0.1 million, respectively (2019 – $0.1 million and $0.1 million, respectively).

- 11 -

 

TRILLIUM THERAPEUTICS INC.

Notes to the Condensed Consolidated Financial Statements (unaudited)
For the three and nine months ended September 30, 2020 and 2019

 

 

10.Commitments and contingencies

 

The Company enters into vendor agreements for the provision of goods and services, which includes manufacturing services with contract manufacturing organizations and development services with contract research organizations. These agreements may include certain provisions for purchase obligations and termination obligations that could require payments for the cancellation of committed purchase obligations or for early termination of the agreements. The amount of the cancellation or termination payments vary and are based on the timing of the cancellation or termination and the specific terms of the agreement and therefore are cancelable contracts.

 

The Company enters into research, development and license agreements in the ordinary course of business where the Company receives research services and rights to proprietary technologies. Milestone and royalty payments that may become due under various agreements are dependent on, among other factors, clinical trials, regulatory approvals and ultimately the successful development of a new drug, the outcome and timing of which are uncertain. Under the license agreement for SIRPαFc, the Company has future contingent milestones payable of $0.2 million and $0.2 million on the first patient dosed in phase 2 and 3 trials, respectively, regulatory milestones on their first achievement totalling $3.8 million, and royalties on commercial sales.

 

The Company has two agreements with Catalent Pharma Solutions pursuant to which Trillium acquired the right to use a proprietary expression system for the manufacture of two SIRPαFc constructs. Consideration for each license includes potential pre-marketing approval milestones of up to $0.9 million and aggregate sales milestone payments of up to $28.8 million.

 

The Company periodically enters into research and license agreements with third parties that include indemnification provisions customary in the industry. These guarantees generally require the Company to compensate the other party for certain damages and costs incurred as a result of claims arising from research and development activities undertaken by or on behalf of the Company. In some cases, the maximum potential amount of future payments that could be required under these indemnification provisions could be unlimited. These indemnification provisions generally survive termination of the underlying agreement. The nature of the indemnification obligations prevents the Company from making a reasonable estimate of the maximum potential amount it could be required to pay. Historically, the Company has not made any indemnification payments under such agreements and no amount has been accrued in the consolidated financial statements with respect to these indemnification obligations.

- 12 -