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EX-31.4 - EX-31.4 - ALEXION PHARMACEUTICALS, INC.alxnex31410-ka12312020.htm
EX-31.3 - EX-31.3 - ALEXION PHARMACEUTICALS, INC.alxnex31310-ka12312020.htm
10-K/A - 10-K/A - ALEXION PHARMACEUTICALS, INC.alxn-20201231.htm

Exhibit 99.1
RECONCILIATION OF NON-GAAP FINANCIAL MEASURES
The following table presents the reconciliation of GAAP to Non-GAAP net income (in millions, except per share amounts) for the years ended December 31, 2020, 2019 and 2018:
Twelve months ended
December 31
202020192018
GAAP net income $603.4 $2,404.3 $77.6 
Before tax adjustments:
Cost of sales:
Share-based compensation12.4 14.2 16.0 
Fair value adjustment in inventory acquired22.9 — — 
Restructuring related expenses — — 5.8 
Research and development expense:
Share-based compensation68.6 61.7 57.4 
Fair value adjustment in inventory acquired4.9 — — 
Upfront payments related to licenses and other strategic agreements— 103.4 26.7 
Restructuring related expenses — — 0.1 
Selling, general and administrative expense:
Share-based compensation179.7 161.1 129.6 
Restructuring related expenses — — 19.4 
Litigation charges 21.6 0.1 13.0 
Gain on sale of asset — — (3.5)
Acquired in-process research and development — (4.1)1,183.0 
Amortization of purchased intangible assets253.7 309.6 320.1 
Change in fair value of contingent consideration 61.2 11.6 116.5 
Acquisition-related costs117.6 — — 
Restructuring expenses 10.3 12.0 25.5 
Impairment of intangible assets2,053.3 — — 
Gain on sale of asset(14.8)— — 
Investment income (expense):
(Gains) and losses related to strategic equity investments(26.6)(59.7)(43.1)
Other income and (expense):
   Gain related to modification of purchase option— (32.0)— 
Restructuring related expenses — — (0.1)
Adjustments to income tax expense (547.2)(584.9)(145.4)
Non-GAAP net income$2,821.0 $2,397.3 $1,798.6 
GAAP earnings per common share - diluted$2.72 $10.70 $0.35 
Non-GAAP earnings per common share - diluted$12.51 $10.53 $7.92 
Shares used in computing diluted earnings per common share (GAAP)222.0 224.8 224.5 
Shares used in computing diluted earnings per common share (non-GAAP)225.5 227.6 227.1