Attached files

file filename
EX-4.1 - EX-4.1 - Prelude Therapeutics Incd935180dex41.htm
EX-3.4 - EX-3.4 - Prelude Therapeutics Incd935180dex34.htm
EX-3.2 - EX-3.2 - Prelude Therapeutics Incd935180dex32.htm
EX-1.1 - EX-1.1 - Prelude Therapeutics Incd935180dex11.htm
S-1/A - S-1/A - Prelude Therapeutics Incd935180ds1a.htm

Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the reference to our firm under the caption “Experts” and to the use of our report dated July 23, 2020, in Amendment No. 1 to the Registration Statement (Form S-1 No. 333-248628) and related Prospectus of Prelude Therapeutics Incorporated dated September 16, 2020.

/s/ Ernst & Young LLP

Philadelphia, Pennsylvania

September 16, 2020