Exhibit 99.1

Case 18-10518-KG    Doc 92    Filed 03/27/18    Page 1 of 2

Docket #0092 Date Filed: 03/27/2018

UNITED STATES BANKRUPTCY COURT

FOR THE DISTRICT OF DELAWARE

INITIAL MONTHLY OPERATING REPORT

File report and attachments with Court and submit copy to United States Trustee within 15 days after order for relief.

Certificates of insurance must name United States Trustee as a party to be notified in the event of policy cancellation.

Bank accounts and checks must bear the name of the debtor, the case number, and the designation “Debtor in Possession.”

Examples of acceptable evidence of Debtor in Possession Bank accounts include voided checks, copy of bank deposit

agreement/certificate of authority, signature card, and/or corporate checking resolution.

I declare under penalty of perjury (28 U.S.C. Section 1746) that this report and the documents attached are true and correct to the best of my knowledge and belief.

		3/27/2018
		Date
Stephen Moglia		VP, Chief Accounting Officer
Printed Name of Authorized Individual		Title of Authorized Individual

Case 18-10518-KG    Doc 92    Filed 03/27/18    Page 2 of 2

Notes

Note 1: The Debtor did not prepare a 12-month cash flow in accordance with Form IR-1; however, pursuant to the DEBTOR’S MOTION FOR ENTRY OF INTERIM AND FINAL ORDERS (I) APPROVING DEBTOR-IN-POSSESSION FINANCING PURSUANT TO 11 U.S.C. §§ 105(a), 362, AND 364, FED. R. BANKR. P. 2002, 4001 AND 9014 AND LOCAL BANKRUPTCY RULE 4001-2; (II) AUTHORIZING USE OF CASH COLLATERAL PURSUANT TO 11 U.S.C. §§ 105, 361, 362 AND 363 OF THE BANKRUPTCY CODE; (III) GRANTING ADEQUATE PROTECTION AND SUPER-PRIORITY ADMINISTRATIVE CLAIMS; (IV) SCHEDULING A FINAL HEARING; AND (V) GRANTING RELATED RELIEF dated March 12, 2018, the Debtor has prepared a 5-week budget (the “Budget”). The Debtor provides the Budget, a copy of which is annexed hereto as Exhibit 1, in lieu of Form IR-1. Note that a new proposed Budget and supporting schedules are required to be delivered to the DIP Lenders on April 4, 2018 and every 2 weeks thereafter.

Note 2: Pursuant to the INTERIM ORDER (A) AUTHORIZING THE DEBTOR TO (I) CONTINUE ITS CASH MANAGEMENT SYSTEM, (II) HONOR CERTAIN RELATED PREPETITION OBLIGATIONS, (III) MAINTAIN EXISTING BUSINESS FORMS, AND (IV) CONTINUE TO PERFORM INTERCOMPANY TRANSACTIONS, (B) AUTHORIZING AND DIRECTING THE DEBTOR’S BANKS TO HONOR ALL RELATED PAYMENT REQUESTS, (C) GRANTING INTERIM AND FINAL WAIVERS OF THE DEBTOR’S COMPLIANCE WITH SECTION 345(B) OF THE BANKRUPTCY CODE, (D) SCHEDULING A FINAL HEARING, AND (E) GRANTING RELATED RELIEF dated March 13, 2018 (the “Interim Cash Management Order”), the Debtor is permitted to maintain its existing bank accounts and is not required to maintain separate Debtor-in-Possession bank accounts. A copy of the Interim Cash Management Order is annexed hereto as Exhibit 3. Additionally, the Debtor provides a list of Debtor bank accounts, a copy of which is also annexed hereto as Exhibit 3.

Case 18-10518-KG    Doc 92-1    Filed 03/27/18    Page 1 of 2

Exhibit 1

Budget

Case 18-10518-KG    Doc 92-1    Filed 03/27/18    Page 2 of 2

Draft - Subject to Material Change

Orexigen Therapeutics, Inc.

DIP Cash Flow Forecast (USD)

$ in 000s

1 of 1

Case 18-10518-KG    Doc 92-2    Filed 03/27/18    Page 1 of 18

Exhibit 2

Certificates of Insurance

CERTIFICATE OF PROPERTY INSURANCE DATE (MM/DD/YYYY) 03/19/2018
THIS CERTIFICATE IS ISSUED AS A MATTER OF INFORMATION ONLY AND CONFERS NO RIGHTS UPON THE CERTIFICATE HOLDER. THIS CERTIFICATE DOES NOT AFFIRMATIVELY OR NEGATIVELY AMEND, EXTEND OR ALTER THE COVERAGE AFFORDED BY THE POLICIES BELOW. THIS CERTIFICATE OF INSURANCE DOES NOT CONSTITUTE A CONTRACT BETWEEN THE ISSUING INSURER(S), AUTHORIZED REPRESENTATIVE OR PRODUCER, AND THE CERTIFICATE HOLDER.
PRODUCER Aon Risk Insurance Services West, Inc. San Francisco CA Office 425 Market Street Suite 2800 San Francisco CA 94105 USA INSURED Orexigen Therapeutics, Inc. 3344 North Torrey Pines Court, Suite 200 La Jolla CA 92037-1024 USA CONTACT NAME: PHONE (A/C. No. Ext): (866) 283-7122    FAX (A/C. No.): (800) 363-0105
E-MAIL ADDRESS: PRODUCER CUSTOMER ID #:    570000072360 INSURER(S) AFFORDING COVERAGE    NAIC #
INSURER A: Hartford Fire Insurance Company INSURER B: Beazley Insurance Company Inc. INSURER C: National Union Fire Insurance Company 19682 37540 19445 INSURER D: INSURER E: INSURER F:
COVERAGES CERTIFICATE NUMBER: 570068256711 REVISION NUMBER:
LOCATION OF PREMISES/DESCRIPTION OF PROPERTY (Attach ACORD 101, Additional Remarks Schedule, if more space is required) THIS IS TO CERTIFY THAT THE POLICIES OF INSURANCE LISTED BELOW HAVE BEEN ISSUED TO THE INSURED NAMED ABOVE FOR THE POLICY PERIOD INDICATED. NOTWITHSTANDING ANY REQUIREMENT, TERM OR CONDITION OF ANY CONTRACT OR OTHER DOCUMENT WITH RESPECT TO WHICH THIS CERTIFICATE MAY ISSUED OR MAY PERTAIN, THE INSURANCE AFFORED BY THE POLICIES DESCRIBED HEREIN IS SUBJECT TO ALL THE TERMS, EXCLUSIONS AND CONDITIONS OF SUCH POLICIES. LIMITS SHOWN MAY HAVE BEEN REDUCED BY PAID CLAIMS. INSR LTR A B C TYPE OF INSURANCE X PROPERTY CAUSES OF LOSS BASIC BOARD X SPECIAL EARTHQUAKE WIND FLOOD Blkt PP Ded DEDUCTIBLES BUILDING CONTENTS X INLAND MARINE CAUSES OF LOSS NAMED PERILS X CRIME TYPE OF POLICY Crime – Primary BOILER & MACHINERY/EQUIPMENT BREAKDOWN POLICY NUMBER 52UUNHB1880 TYPE OF POLICY Marine Cargo POLICY NUMBER V135E617PNGF 017718302 POLICY EFFECTIVE DATE (MM/DD/YYYY) 08/01/2017 08/01/2017 08/01/2017 POLICY EXPIRATION DATE (MM/DD/YYYY) 08/01/2017 08/01/2018 08/01/2018 COVERED PROPERTY BUILDING PERSONAL PROPERTY X BUSINESS INCOME X EXTRA EXPENSE RENTAL VALUE BLANKET BUILDING X BLANKET PERS PROP BLANKET BLDG & PP X Deductible
X Any One Conveyance X Deductible X Employee Dishonesty X Deductible LIMITS $625,000 Included $3,500,000 $2,500 $7,000,000 $100,000 $1,000,000 $10,000 SPECIAL CONDITIONS/OTHER COVERAGES (ACORD 101, Additional Remarks Schedule, may be attached if more space is required) Certificate Holder shall receive notice of cancellation in accordance with policy provisions. See attached endorsements. CERTIFICATE HOLDER CANCELLATION Office of the United States Trustee Lockbox 35 844 King Street Wilmington, DE 19801 USA SHOULD ANY OF THE ABOVE DESCRIBED POLICIES BE CANCELLED BEFORE THE EXPIRATION DATE THEREOF, NOTICE WILL BE DELIVERED IN ACCORDANCE WITH THE POLICY PROVISIONS. AUTHORIZED REPRESENTATIVE 1995-2015 ACORD CORPORATION. All rights reserved. ACORD 24 (2016/03) The ACORD name and logo are registered marks of ACORD

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 3 of 18 POLICY NUMBER: 52 UUN HB1880
THIS ENDORSEMENT CHANGES THE POLICY. PLEASE READ IT CAREFULLY.
NOTICE OF CANCELLATION OR NONRENEWAL
TO DESIGNATED CERTIFICATE HOLDER
SCHEDULE Number of Days Notice: Part A: __30     Part B: __30     Part C: __30     Part D: __30    
Name of Certificate Holder:
OFFICE OF THE UNITED STATES TRUSTEE
Mailing Address:
LOCKBOX 35 844 KING STREET WILMINGTON, DE 19801
This policy is subject to the following additional Conditions when a number of days are shown in the Schedule for any of the above Parts. A.    If this policy is cancelled by the Company, other than for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule, at least the number of days in advance of the cancellation effective date, as shown in Part A.
B.    If this policy is cancelled by the Company for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule within the number of days notice of the cancellation effective date, as shown in Part B.
C.    If this policy is cancelled by the insured, notice of such cancellation will be provided to the certificate holder in the Schedule, within the number of days notice of the cancellation effective date, as shown in Part C.
D.    If this policy is nonrenewed by the Company, notice of such nonrenewal will be provided to the certificate holder in the Schedule, at least the number of days in advance of the nonrenewal effective date, as shown in Part D.
If notice is mailed, proof of mailing notice to the certificate holder’s mailing address as shown in the Schedule will be sufficient proof of notice. If the number of days notice in the Schedule for any Part is left blank or is shown as zero, no notice will be provided to the Scheduled certificate holder under that Part. Any notification rights provided by this endorsement apply only to active certificate holder(s) who were issued a certificate of insurance applicable to this policy’s term. Failure to provide such notice to the certificate holder(s) will not amend or extend the date the cancellation becomes effective, nor will it negate cancellation of the policy. Failure to send notice shall impose no liability of any kind upon the Company or its agents or representatives.

Form IH 03 16 06 11 © 2011, The Hartford Page 1 of 1
Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 4 of 18 BEAZLEY INSURANCE COMPANY, INC.
Endorsement No: 13
Effective date of this Endorsement: March 20, 2018
Issued date of this Endorsement: March 20, 2018
This Endorsement is attached to and forms a part of Policy Number: V135E617PNGF “Insurer” Referred to in this endorsement is Beazley
CHAPTER 11 BANKRUPTCY FILING NOTICE
This endorsement modifies insurance provided under the following:
Beazley FCU Marine Cargo Form—F00210
It is hereby understood and agreed that, as the Named Insured, Orexigen Therapeutics, Inc., has filed for
Chapter 11 Bankruptcy in the United States Bankruptcy Court for the District of Delaware, case No.
18-10518 (KG), this Insurer agrees that, in the event of any cancellation of policy V135E617PNGF, notice will be sent to the following office with notification of said cancellation:
OFFICE OF THE UNITED STATES TRUSTEE
LOCKBOX 35
844 KING STREET
WILMINGTON, DE 19801
All other terms and conditions of this Policy remain unchanged.
Authorized Signature EOT007 032018 ed. Page 1 of 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 5 of 18 CERTIFICATE OF LIABILITY INSURANCE DATE(MM/DD/YYYY) 03/19/2018 THIS CERTIFICATE IS ISSUED AS A MATTER OF INFORMATION ONLY AND CONFERS NO RIGHTS UPON THE CERTIFICATE HOLDER. THIS CERTIFICATE DOES NOT AFFIRMATIVELY OR NEGATIVELY AMEND, EXTEND OR ALTER THE COVERAGE AFFORDED BY THE POLICIES BELOW. THIS CERTIFICATE OF INSURANCE DOES NOT CONSTITUTE A CONTRACT BETWEEN THE ISSUING INSURER(S), AUTHORIZED REPRESENTATIVE OR PRODUCER, AND THE CERTIFICATE HOLDER. IMPORTANT: If the certificate holder is an ADDITIONAL INSURED, the policy(ies) must have ADDITIONAL INSURED provisions or be endorsed. If SUBROGATION IS WAIVED, subject to the terms and conditions of the policy, certain policies may require an endorsement. A statement on this certificate does not confer rights to the certificate holder in lieu of such endorsement(s). PRODUCER Aon Risk Insurance Services West, Inc. San Francisco CA Office 425 Market Street Suite 2800 San Francisco CA 94105 USA INSURED Orexigen Therapeutics, Inc. 3344 North Torrey Pines Court, Suite 200 La Jolla CA 92037-1024 USA CONTACT NAME: PHONE (A/C. No. Ext): (866) 283-7122    FAX (A/C. No.): (800) 363-0105 E-MAIL ADDRESS: INSURER(S) AFFORDING COVERAGE INSURER A:    Hartford Underwriters Insurance Company INSURER B:    Hartford Fire Insurance Co. INSURER C:    Hartford Casualty Insurance Co INSURER D:    Trumbull Insurance Company INSURER E: National Union Fire Insurance Company INSURER F:    Ironshore Specialty Insurance Company NAIC # 30104 19682 29424 27120 19445 25445 COVERAGES CERTIFICATE NUMBER: 570069271073 REVISION NUMBER: THIS IS TO CERTIFY THAT THE POLICIES OF INSURANCE LISTED BELOW HAVE BEEN ISSUED TO THE INSURED NAMED ABOVE FOR THE POLICY PERIOD INDICATED. NOTWITHSTANDING ANY REQUIREMENT, TERM OR CONDITION OF ANY CONTRACT OR OTHER DOCUMENT WITH RESPECT TO WHICH THIS CERTIFICATE MAY BE ISSUED OR MAY PERTAIN, THE INSURANCE AFFORDED BY THE POLICIES DESCRIBED HEREIN IS SUBJECT TO ALL THE TERMS, EXCLUSIONS AND CONDITIONS OF SUCH POLICIES. LIMITS SHOWN MAY HAVE BEEN REDUCED BY PAID CLAIMS.    Limits shown are as requested INSR LTR A TYPE OF INSURANCE X    COMMERCIAL GENERAL LIABILITY CLAIMS-MADE X OCCUR ADDL INSD    SUBR WVD    POLICY NUMBER POLICY EFF (MM/DD/YYYY)    POLICY EXP (MM/DD/YYYY)    LIMITS GEN’L AGGREGATE LIMIT APPLIES PER: X POLICY PROJECT LOC OTHER: 52 UUN HB1880 08/01/2017 08/01/2018 EACH OCCURRENCE DAMAGE TO RENTED PREMISES (Ea occurrence) MED EXP (Any one person) PERSONAL & ADV INJURY GENERAL AGGREGATE PRODUCTS - COMP/OP AGG $1,000,000 $300,000 $10,000 $1,000,000 $2,000,000 Excluded B C D E AUTOMOBILE LIABILITY X ANY AUTO OWNED AUTOS ONLY HIRED AUTOS ONLY X Comp Ded $1000 SCHEDULED AUTOS NON-OWNED AUTOS ONLY X Coll Ded $1000 X UMBRELLA LIAB EXCESS LIAB X OCCUR CLAIMS-MADE DED X RETENTION WORKERS COMPENSATION AND EMPLOYERS’ LIABILITY ANY PROPRIETOR / PARTNER / EXECUTIVE OFFICER/MEMBER EXCLUDED? (Mandatory in NH) If yes, describe under DESCRIPTION OF OPERATIONS below Y / N N N/A Cyber Liability 52 UUN HB1880 08/01/2017 08/01/2018 52RHUHB1043 SIR applies per policy terms & conditions 08/01/2017 08/01/2018 52WEAB4288 Work Comp 08/01/2017    08/01/2018 017723550 Claims-Made SIR applies per policy terms & conditions 08/01/2017 08/01/2018 COMBINED SINGLE LIMIT (Ea accident) BODILY INJURY ( Per person) BODILY INJURY (Per accident) PROPERTY DAMAGE (Per accident) EACH OCCURRENCE AGGREGATE X PER    OTH X STATUTE    ER E.L. EACH ACCIDENT E.L. DISEASE-EA EMPLOYEE E.L. DISEASE-POLICY LIMIT Aggregate $1,000,000 $10,000,000 $10,000,000 $1,000,000 $1,000,000 $1,000,000 $3,000,000 DESCRIPTION OF OPERATIONS / LOCATIONS / VEHICLES (ACORD 101, Additional Remarks Schedule, may be attached if more space is required)
Certificate Holder shall receive notice of cancellation in accordance with policy provisions. See attached endorsements.
CERTIFICATE HOLDER
Office of the United States Trustee Lockbox 35 844 King Street Wilmington, DE 19801 USA
CANCELLATION
SHOULD ANY OF THE ABOVE DESCRIBED POLICIES BE CANCELLED BEFORE THE EXPIRATION DATE THEREOF, NOTICE WILL BE DELIVERED IN ACCORDANCE WITH THE POLICY PROVISIONS. AUTHORIZED REPRESENTATIVE
©1988-2015 ACORD CORPORATION. All rights reserved. The ACORD name and logo are registered marks of ACORD
ACORD 25 (2016/03)
Certificate No: 570069271073 Holder Identifier:

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 6 of 18
AGENCY CUSTOMER ID: 570000072360 LOC #:
ADDITIONAL REMARKS SCHEDULE Page of
AGENCY
Aon Risk Insurance Services West, Inc.
POLICY NUMBER
See Certificate Number: 570067935259
CARRIER See Certificate Number: 570067935259 NAIC CODE
NAMED INSURED Orexigen Therapeutics, Inc. EFFECTIVE DATE:
ADDITIONAL REMARKS FORM IS A SCHEDULE TO ACORD FORM, FORM NUMBER: ACORD 25 FORM TITLE: Certificate of Liability Insurance
INSURER(S) AFFORDING COVERAGE
INSURER G Federal Insurance Company
INSURER H Navigators Specialty Insurance Company
INSURER
INSURER
NAIC #
20281
36056
ADDITIONAL POLICIES If a policy below does not include limit information, refer to the corresponding policy on the ACORD certificate form for policy limits.
INSR LTR F G H
TYPE OF INSURANCE PRODUCTS LIABILITY PRIMARY EXCESS EXCESS
ADDL INSD    SUBR WVD
POLICY NUMBER Claims-Made SIR applies per policy teams & conditions 003247900 79899138 OC17LEXOBEEJRNC
POLICY EFFECTIVE DATE (MM/DD/YYYY) 08/01/2017 08/01/2017 08/01/2017
POLICY EXPIRATION DATE (MM/DD/YYYY) 08/01/2018 08/01/2018 08/01/2018 LIMITS
Aggregate Aggregate Aggregate $5,000,000 $5,000,000 $10,000,000 ACORD 101 (2008/01) © 2008 ACORD CORPORATION. All rights reserved. The ACORD name and logo are registered marks of ACORD

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 7 of 18
POLICY NUMBER: 52 UUN HB1880
THIS ENDORSEMENT CHANGES THE POLICY. PLEASE READ IT CAREFULLY. NOTICE OF CANCELLATION OR NONRENEWAL TO DESIGNATED CERTIFICATE HOLDER
Number of Days Notice:
SCHEDULE
Part A: __30    
Part B: __30    
Part C: __30    
Part D: __30    
Name of Certificate Holder:
OFFICE OF THE UNITED STATES TRUSTEE
Mailing Address:
LOCKBOX 35 844 KING STREET WILMINGTON, DE 19801
This policy is subject to the following additional Conditions when a number of days are shown in the Schedule for any of the above Parts.
A.    If this policy is cancelled by the Company, other than for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule, at least the number of days in advance of the cancellation effective date, as shown in Part A.
B.    If this policy is cancelled by the Company for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule within the number of days notice of the cancellation effective date, as shown in Part B.
C.    If this policy is cancelled by the insured, notice of such cancellation will be provided to the certificate holder in the Schedule, within the number of days notice of the cancellation effective date, as shown in Part C.
D.    If this policy is nonrenewed by the Company, notice of such nonrenewal will be provided to the certificate holder in the Schedule, at least the number of days in advance of the nonrenewal effective date, as shown in Part D.
If notice is mailed, proof of mailing notice to the certificate holder’s mailing address as shown in the Schedule will be sufficient proof of notice. If the number of days notice in the Schedule for any Part is left blank or is shown as zero, no notice will be provided to the Scheduled certificate holder under that Part.
Any notification rights provided by this endorsement apply only to active certificate holder(s) who were issued a certificate of insurance applicable to this policy’s term.
Failure to provide such notice to the certificate holder(s) will not amend or extend the date the cancellation becomes effective, nor will it negate cancellation of the policy. Failure to send notice shall impose no liability of any kind upon the Company or its agents or representatives.
Form IH 03 16 06 11© 2011, The Hartford Page 1 of 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 8 of 18
Chubb Commercial Excess Follow-Form Insurance
Premium Bill
Policy Period AUGUST 01, 2017 To AUGUST 01, 2018
Effective Date March 12, 2018 Policy Number 7989-91-38 Insured OREXIGEN THERAPEUTICS INC
Name of Company FEDERAL INSURANCE COMPANY
Date Issued March 19, 2018 Producer AON RISK INSURANCE SERVICES WEST INC
THIS BILLING IS TO BE ATTACHED TO AND FORM A PART OF THE POLICY
PLEASE SEND PAYMENT TO AGENT OR BROKER, IF APPLICABLE
Coverage
ADDITIONAL PREMIUM COMMERCIAL EXCESS ADD FORM 07-02-2469: NOTICE OF CANCEL SCHED PERSONS/ORG EXCPT NP.
Commission Rate 15.0% Premium $0.00
Total $0.00 Portion of total premium attributable for Terrorism and statutory standard fire where applicable is: $0.00
Form 07-10-0542 (ED. 10-06) last page page 1 Premium Bill

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 9 of 18
Chubb Commercial Excess Follow-Form Insurance
Endorsement
Policy Period AUGUST 01, 2017 To AUGUST 01, 2018 Effective Date March 12, 2018 Policy Number 7989-91-38 LAO Insured OREXIGEN THERAPEUTICS INC Name of Company FEDERAL INSURANCE COMPANY Date Issued March 19, 2018
Under Conditions, the following condition is added.
Conditions
Notice of Cancellation To Scheduled Persons Or Organizations When We Cancel
When we cancel this policy for any reason, other than non-payment of premium, we will notify person(s) or organization(s) shown in the Schedule at least 30 days in advance of the cancellation date.
Any failure by us to notify such person(s) or organization(s) will not:
impose any liability or obligation of any kind upon us; or invalidate such cancellation.
Schedule
Peron(s) or Organizations(s): OFFICE OF THE UNITED STATES TRUSTEE LOCKBOX 35
Address: 844 KING STREET WILMINGTON, DE 19801.
All other terms and conditions remain unchanged.
Authorized Representative
Chubb Commercial Excess Follow-Form Insurance
Form 07-02-2469 (ED. 8-11)
Notice of Cancellation To Scheduled Persons or Organizations (Except Non-Payment Of Premium) Endorsement last page Page 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 10 of 18 AIRONSHORE
A Liberty Mutual Company
IRONSHORE SPECIALTY INSURANCE COMPANY
Mailing Address:
75 Federal Street
5th Floor
Boston, MA 02110
Toll Free: (877) IRON411
Endorsement # 13
Policy Number: 003247900
Insured Name: Orexigen Therapeutics, Inc.
Effective Date of Endorsement: March 12, 2018
THIS ENDORSEMENT CHANGES THE POLICY. PLEASE READ IT CAREFULLY.
CANCELLATION NOTICE TO THIRD PARTY
In consideration of the premium charged, it is hereby agreed that, in the event of the cancellation of this Policy by the Insurer, the Insurer will send notice to the individual or entity shown below at the address shown below of such cancellation at least 30 days in advance of the effective date of cancellation, or 10 days in advance in the event of non-payment of premium:
Name: OFFICE OF THE UNITED STATES TRUSTEE
Address: LOCKBOX 35, 844 KING STREET, WILMINGTON, DE 19801
Any failure on the Insurer’s part to deliver such notice will not impose liability of any kind upon the Insurer or invalidate the cancellation.
All other terms and conditions of this Policy remain unchanged.
Authorized Representative March 20, 2018 Date
LFS.END.248 (12.14 ed.)     Page: 1 of 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 11 of 18
THIS ENDORSEMENT CHANGES THE POLICY. PLEASE READ IT CAREFULLY.
CHANGE ENDORSEMENT
It is hereby understood and agreed upon that the following forms have been added to the policy:
NAV LSC 012 01 16- NOTICE OF CANCELLATION TO DESIGNATED PERSON(S) OR ORGANIZATION(S) OTHER THAN THE NAMED INSURED
ALL OTHER TERMS AND CONDITIONS OF THE POLICY REMAIN UNCHANGED.
The premium for this endorsement is included in the premium shown on the declarations unless a specific amount is shown here:
ENDORSEMENT NO : 001 Premium: $0 Effective: 03/12/2018
is attached to and forms part of your evidence of insurance no.:    OC17LEX0BEEJRNC
Issued by:    Navigators Specialty Insurance Company
Executive Offices: One Penn Plaza / New York, NY 10119
Insured: Orexigen Therapeutics Inc.
Date Issued 3/19/2018 Authorized Representative:
NPC-907 08 07 Page 1 of 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 12 of 18
THIS ENDORSEMENT CHANGES THE POLICY.
PLEASE READ IT CAREFULLY.
NOTICE OF CANCELLATION TO DESIGNATED PERSON(S) OR
ORGANIZATION(S) OTHER THAN THE NAMED INSURED
This endorsement modifies insurance provided under the following:
GLS ELITE PRODUCTS-COMPLETED OPERATIONS LIABILITY COVERAGE
GLS ELITE PRODUCTS-COMPLETED OPERATIONS AND PROFESSIONAL LIABILITY COVERAGE
FOLLOWING FORM EXCESS LIABILITY
The following is added to Section V. CONDITIONS:
SCHEDULE
Number of Days Notice: 60
Name of Person(s) or Organization(s): OFFICE OF THE UNITED STATES TRUSTEE
Mailing Address: Lockbox 35
844 King Street Wilmington, DE 19801
If this policy is cancelled, we agree that the person(s) or organization(s) listed in the Schedule above will be notified at least:
a.    10 days before the effective date of cancellation if we cancel for non-payment of premium; or
b.    The number of days shown in the Schedule above before the effective date of cancellation if we cancel
for any other reason.
In no event, however, will notice of cancellation be less than the minimum number of days required by the jurisdiction to which this endorsement applies.
If notice is mailed, proof of mailing to the address shown in the Schedule above will be sufficient proof of notice.
ALL OTHER TERMS AND CONDITIONS OF THE POLICY REMAIN UNCHANGED.
May contain copyrighted material of the
Insurance Service Office, Inc with its permission.
NAVLSC012 01 16 Navigators Life Sciences Page 1 of 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 13 of 18
POLICY NUMBER: 52 RHU HB1043
THIS ENDORSEMENT CHANGES THE POLICY. PLEASE READ IT CAREFULLY.
NOTICE OF CANCELLATION OR NONRENEWAL
TO DESIGNATED CERTIFICATE HOLDER
SCHEDULE
Number of Days Notice:
Part A: __30    
Part B: __30    
Part C: __30    
Part D: __30    
Name of Certificate Holder:
OFFICE OF THE UNITED STATES TRUSTEE
Mailing Address:
LOCKBOX 35 844 KING STREET WILMINGTON, DE 19801
This policy is subject to the following additional Conditions when a number of days are shown in the Schedule for any of the above Parts.
A.    If this policy is cancelled by the Company, other than for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule, at least the number of days in advance of the cancellation effective date, as shown in Part A.
B.    If this policy is cancelled by the Company for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule within the number of days notice of the cancellation effective date, as shown in Part B.
C.    If this policy is cancelled by the insured, notice of such cancellation will be provided to the certificate holder in the Schedule, within the number of days notice of the cancellation effective date, as shown in Part C.
D.    If this policy is nonrenewed by the Company, notice of such nonrenewal will be provided to the certificate holder in the Schedule, at least the number of days in advance of the nonrenewal effective date, as shown in Part D.
If notice is mailed, proof of mailing notice to the certificate holder’s mailing address as shown in the Schedule will be sufficient proof of notice. If the number of days notice in the Schedule for any Part is left blank or is shown as zero, no notice will be provided to the Scheduled certificate holder under that Part.
Any notification rights provided by this endorsement apply only to active certificate holder(s) who were issued a certificate of insurance applicable to this policy’s term.
Failure to provide such notice to the certificate holder(s) will not amend or extend the date the cancellation becomes effective, nor will it negate cancellation of the policy. Failure to send notice shall impose no liability of any kind upon the Company or its agents or representatives.
Form IH 03 16 06 11 © 2011, The Hartford Page 1 of 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 14 of 18
POLICY NUMBER: 52 WE AB4288
THIS ENDORSEMENT CHANGES THE POLICY. PLEASE READ IT CAREFULLY.
NOTICE OF CANCELLATION OR NONRENEWAL
TO DESIGNATED CERTIFICATE HOLDER
SCHEDULE
Number of Days Notice:
Part A: __30    
Part B: __30    
Part C: __30    
Part D: __30    
Name of Certificate Holder:
OFFICE OF THE UNITED STATES TRUSTEE
Mailing Address:
LOCKBOX 35 844 KING STREET WILMINGTON, DE 19801
This policy is subject to the following additional Conditions when a number of days are shown in the Schedule for any of the above Parts.
A.    If this policy is cancelled by the Company, other than for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule, at least the number of days in advance of the cancellation effective date, as shown in Part A.
B.    If this policy is cancelled by the Company for nonpayment of premium, notice of such cancellation will be provided to the certificate holder in the Schedule within the number of days notice of the cancellation effective date, as shown in Part B.
C.    If this policy is cancelled by the insured, notice of such cancellation will be provided to the certificate holder in the Schedule, within the number of days notice of the cancellation effective date, as shown in Part C.
D.    If this policy is nonrenewed by the Company, notice of such nonrenewal will be provided to the certificate holder in the Schedule, at least the number of days in advance of the nonrenewal effective date, as shown in Part D.
If notice is mailed, proof of mailing notice to the certificate holder’s mailing address as shown in the Schedule will be sufficient proof of notice. If the number of days notice in the Schedule for any Part is left blank or is shown as zero, no notice will be provided to the Scheduled certificate holder under that Part.
Any notification rights provided by this endorsement apply only to active certificate holder(s) who were issued a certificate of insurance applicable to this policy’s term.
Failure to provide such notice to the certificate holder(s) will not amend or extend the date the cancellation becomes effective, nor will it negate cancellation of the policy. Failure to send notice shall impose no liability of any kind upon the Company or its agents or representatives.
Form IH 03 16 06 11 © 2011, The Hartford Page 1 of 1

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 15 of 18
CERTIFICATE OF LIABILITY INSURANCE DATE(MM/DD/YYYY) 03/26/2018
THIS CERTIFICATE IS ISSUED AS A MATTER OF INFORMATION ONLY AND CONFERS NO RIGHTS UPON THE CERTIFICATE HOLDER. THIS CERTIFICATE DOES NOT AFFIRMATIVELY OR NEGATIVELY AMEND, EXTEND OR ALTER THE COVERAGE AFFORDED BY THE POLICIES BELOW. THIS CERTIFICATE OF INSURANCE DOES NOT CONSTITUTE A CONTRACT BETWEEN THE ISSUING INSURER(S), AUTHORIZED REPRESENTATIVE OR PRODUCER, AND THE CERTIFICATE HOLDER.
IMPORTANT: If the certificate holder is an ADDITIONAL INSURED, the policy(ies) must have ADDITIONAL INSURED provisions or be endorsed. If SUBROGATION IS WAIVED, subject to the terms and conditions of the policy, certain policies may require an endorsement. A statement on this certificate does not confer rights to the certificate holder in lieu of such endorsement(s).
PRODUCER
Aon Risk Insurance Services West, Inc.
San Francisco CA Office
425 Market Street
Suite 2800
San Francisco CA 94105 USA
INSURED
Orexigen Therapeutics, Inc.
3344 North Torrey Pines Court, Suite 200
La Jolla CA 92037-1024 USA
CONTACT NAME: PHONE (A/C. No. Ext): (866) 283-7122 FAX (A/C. No.): (800) 363-0105
E-MAIL ADDRESS:
INSURER(S) AFFORDING COVERAGE
INSURER A:    The Continental Insurance Company
INSURER B:    Scottsadale Insurance Co.
INSURER C:    National Union Fire Insurance Company
INSURER D:    XL Specialty Insurance Company
INSURER E:    Old Republic Insurance Company
INSURER F:    Argonaut Insurance Company
NAIC #
35289
41297
19445
37885
24147
19801
COVERAGES CERTIFICATE NUMBER: 570069271073 REVISION NUMBER:
THIS IS TO CERTIFY THAT THE POLICIES OF INSURANCE LISTED BELOW HAVE BEEN ISSUED TO THE INSURED NAMED ABOVE FOR THE POLICY PERIOD INDICATED. NOTWITHSTANDING ANY REQUIREMENT, TERM OR CONDITION OF ANY CONTRACT OR OTHER DOCUMENT WITH RESPECT TO WHICH THIS CERTIFICATE MAY BE ISSUED OR MAY PERTAIN, THE INSURANCE AFFORDED BY THE POLICIES DESCRIBED HEREIN IS SUBJECT TO ALL THE TERMS, EXCLUSIONS AND CONDITIONS OF SUCH POLICIES. LIMITS SHOWN MAY HAVE BEEN REDUCED BY PAID CLAIMS.    Limits shown are as requested
INSR LTR A B C TYPE OF INSURANCE
X    COMMERCIAL GENERAL LIABILITY
CLAIMS-MADE X OCCUR
GEN’L AGGREGATE LIMIT APPLIES PER:
X POLICY PROJECT LOC
X    OTHER: IRELAND LOCAL LIABILITY
ANY AUTO OWNED AUTOS ONLY HIRED AUTOS ONLY Comp Ded $1000
SCHEDULED AUTOS NON-OWNED AUTOS ONLY Coll Ded $1000
UMBRELLA LIAB EXCESS LIAB OCCUR CLAIMS-MADE     DED | RETENTION
WORKERS COMPENSATION AND EMPLOYERS’ LIABILITY
ANY PROPRIETOR / PARTNER / EXECUTIVE OFFICER/MEMBER EXCLUDED? (Mandatory in NH) If yes, describe under DESCRIPTION OF OPERATIONS below Y / N N / A
EMPLOYMENT PRACTICES LIABILITY FIDUCIARY LIABILITY
ADDL INSD SUBR WVD
POLICY NUMBER WP623250050 Foreign Liability
EKS3229323 017718315 SIR applies per policy terms & conditions
POLICY EFF (MM/DD/YYYY) 08/01/2017 08/01/2017 08/01/2017    
POLICY EXP (MM/DD/YYYY) 08/01/2018 08/01/2018 08/01/2018
LIMITS
EACH OCCURRENCE
DAMAGE TO RENTED PREMISES (Ea occurrence)
MED EXP (Any one person)
PERSONAL & ADV INJURY
GENERAL AGGREGATE
PRODUCTS - COMP/OP AGG
COMBINED SINGLE LIMIT (Ea accident)
BODILY INJURY ( Per person)
BODILY INJURY (Per accident)
PROPERTY DAMAGE
(Per accident)
EACH OCCURRENCE
AGGREGATE
PER STATUTE    OTHER
E.L. EACH ACCIDENT
E.L. DISEASE-EA EMPLOYEE
E.L. DISEASE-POLICY LIMIT
Aggregate
Aggregate
$1,000,000
$1,000,000
$10,000
$1,000,000
$2,000,000
Excluded
$4,000,000
$3,000,000
DESCRIPTION OF OPERATIONS / LOCATIONS / VEHICLES (ACORD 101, Additional Remarks Schedule, may be attached if more space is required) Certificate Holder shall receive notice of cancellation in accordance with policy provisions. See attached endorsements.
CERTIFICATE HOLDER CANCELLATION
Office of the United States Trustee
Lockbox 35
844 King Street
Wilmington, DE 19801 USA SHOULD ANY OF THE ABOVE DESCRIBED POLICIES BE CANCELLED BEFORE THE EXPIRATION DATE THEREOF, NOTICE WILL BE DELIVERED IN ACCORDANCE WITH THE POLICY PROVISIONS. AUTHORIZED REPRESENTATIVE ACORD 25 (2016/03) ©1988-2015 ACORD CORPORATION. All rights reserved. The ACORD name and logo are registered marks of ACORD
Certificate No : 570069271073 Holder Identifier :

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 16 of 18
AGENCY CUSTOMER ID: 570000072360
LOC #:
ADDITIONAL REMARKS SCHEDULE Page of
AGENCY Aon Risk Insurance Services West, Inc.
POLICY NUMBER See Certificate Number: 570067935259
CARRIER See Certificate Number: 570067935259 NAIC CODE
NAMED INSURED Orexigen Therapeutics, Inc.
EFFECTIVE DATE: ADDITIONAL REMARKS
THIS ADDITIONAL REMARKS FORM IS A SCHEDULE TO ACORD FORM, FORM NUMBER: ACORD 25 FORM TITLE: Certificate of Liability Insurance
INSURER(S) AFFORDING COVERAGE
INSURER G Hudson Insurance Company
INSURER
INSURER
INSURER
NAIC #
25054
ADDITIONAL POLICIES If a policy below does not include limit information, refer to the corresponding policy on the ACORD certificate form for policy limits.
INSR LTR C D E F G C
TYPE OF INSURANCE
DIRECTORS & OFFICERS LIABILITY
PRIMARY
EXCESS
EXCESS
EXCESS
EXCESS - Side A
EXCESS - Side A
ADDL INSD SUBR WVD
POLICY NUMBER
Claims-Made SIR applies per policy terms & conditions
017718063
ELU15140217
ORPRO39808
MLX60273300
HN03032096080117
017718070
POLICY
EFFECTIVE
DATE
(MM/DD/YYYY)
08/01/2017
08/01/2017
08/01/2017
08/01/2017
08/01/2017
08/01/2017
POLICY
EXPIRATION
DATE
(MM/DD/YYYY)
08/01/2018
08/01/2018
08/01/2018
08/01/2018
08/01/2018
08/01/2018
LIMITS
Aggregate
Aggregate
Aggregate
Aggregate
Aggregate
Aggregate
$10,000,000
$10,000,000
$5,000,000
$5,000,000
$5,000,000
$5,000,000
ACORD 101 (2008/01)
© 2008 ACORD CORPORATION. All rights reserved.
The ACORD name and logo are registered marks of ACORD

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 17 of 18
CNA PARAMOUNT – INTERNATIONAL
Amendment of Forms and Endorsements Schedule - Addition or Deletion of Endorsements
It is understood and agreed as follows:
I. ADDITION OF FORMS OR ENDORSEMENTS
The Forms and Endorsements Schedule is amended to add the following forms or endorsements effective as of the date set forth in such form or endorsement.
Endorsement No 1
Form or Endorsement Name
Changes - Notice of Cancellation, Non-Renewal or Material Restriction Endorsement
Form Number CNA74702WW
Edition Date 8-16
Effective Date 3/12/2018 Additional /
Return Premium $0
II. DELETION OF FORMS OR ENDORSEMENTS
The Forms and Endorsements Schedule is amended to delete the following forms or endorsements effective as of the “deletion date” indicated below.
Endorsement No
Form or Endorsement Name
Form Number
Edition Date
Deletion Date
Additional / Return Premium
The net premium change, if any, for the above endorsements in Sections I. and II. is: $0 Countersignature fees (if applicable):
Total change is: $0
All other terms and conditions of the Policy remain unchanged. This endorsement, which forms a part of and is for attachment to the Policy issued by the designated Insurers, takes effect on the effective date of said Policy at the hour stated in said Policy, unless another effective date is shown below, and expires concurrently with said Policy.
Insured Name: Orexigen Therapeutics, Inc. Policy No: WP 62 325 0050 CNA87598XX (11-16) Page 1 of 1 Copyright CNA All Rights Reserved.

Case 18-10518-KG Doc 92-2 Filed 03/27/18 Page 18 of 18
CNA PARAMOUNT – INTERNATIONAL Changes - Notice Of Cancellation, Non-Renewal Or Material Restriction Endorsement
This endorsement modifies insurance provided under the following: COMMON TERMS AND CONDITIONS SCHEDULE
90 Number of days notice for cancellation (other than for nonpayment of premium) or material change
10 Number of days notice of cancellation for nonpayment of premium*
60 Number of days notice for non-renewal
Name of person or organization to whom notice will be sent:
Address : Office of the United States Trustee
Lockbox 35, 844 King Street, Wilmington, DE 19801
(* If no entry appears above, the number of days notice for nonpayment of premium will be 10 days.)
It is understood and agreed that the following is added to the Condition entitled CANCELLATION/NONRENEWAL.
Notice to Others
In the event of cancellation or any material restrictions in coverage during the policy period, or in the event the Insurer decides not to renew this policy, the Insurer also agrees to mail prior written notice of such cancellation, material restriction or nonrenewal to the person or organization listed in the above Schedule. Such notice will be sent prior to such cancellation in the manner prescribed in the above Schedule.
All other terms and conditions of the Policy remain unchanged.
This endorsement, which forms a part of and is for attachment to the Policy issued by the designated Insurers, takes
effect on the effective date of said Policy at the hour stated in said Policy, unless another effective date is shown below,
and expires concurrently with said Policy.
CNA74702WW (8-16) Page 1 of 1 Copyright CNA All Rights Reserved.

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 1 of 11
Exhibit 3 Bank Accounts

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 2 of 11
Docket #0047 Date Filed: 03/13/2018
IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE
In re Orexigen Therapeutics, Inc., Debtor.1
Chapter 11
Case No. 18-10518 (KG)
Re: D.I. 7
INTERIM ORDER GRANTING DEBTOR’S MOTION FOR ENTRY OF INTERIM AND FINAL ORDERS (A) AUTHORIZING THE DEBTOR TO (I) CONTINUE ITS CASH MANAGEMENT SYSTEM, (II) HONOR CERTAIN RELATED PREPETITION OBLIGATIONS, (III) MAINTAIN EXISTING BUSINESS FORMS, AND (IV) CONTINUE TO PERFORM INTERCOMPANY TRANSACTIONS, (B) AUTHORIZING AND DIRECTING THE DEBTOR’S BANKS TO HONOR ALL RELATED PAYMENT REQUESTS, (C) GRANTING INTERIM AND FINAL WAIVERS OF THE DEBTOR’S COMPLIANCE WITH SECTION 345(B) OF THE BANKRUPTCY CODE, (D) SCHEDULING A FINAL HEARING, AND (E) GRANTING RELATED RELIEF
Upon the motion (the “Motion”)2 of the above-captioned debtor and debtor in possession
(the “Debtor”) for entry of interim (this “Interim Order”) and final orders, (a) authorizing the
Debtor to (i) continue its Cash Management System, (ii) honor certain related prepetition obligations, (iii) maintain its existing Business Forms in the ordinary course of business, and (iv) continue to perform the Intercompany Transactions in the ordinary course and with the consent of the DIP Administrative Agent (b) authorizing and directing the Debtor’s Banks to honor all
related payment requests, (c) waiving the Debtor’s compliance with investment guidelines set forth in section 345(b) of the Bankruptcy Code, (d) scheduling a final hearing (the “Final Hearing”) to consider entry of the proposed final order granting the Motion and (e) granting related relief, all as more fully set forth in the Motion; and upon the First Day Declaration; and
1 The last four digits of the Debtor’s federal tax identification number are 8822. The Debtor’s mailing address for purposes of this Chapter 11 Case is 3344 North Torrey Pines Court, Suite 200, La Jolla, CA, 92037.
2 Capitalized terms not defined in this Order are defined in the Motion.
1810518180313000000000020

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 3 of 11
this Court having jurisdiction over this matter pursuant to 28 U.S.C. §§ 157 and 1334 and the Amended Standing Order of Reference from the United States District Court for the District of Delaware, dated February 29, 2012; and this Court having found that this is a core proceeding pursuant to 28 U.S.C. § 157(b)(2); and that this Court may enter a final order consistent with Article III of the United States Constitution; and this Court having found that venue of this proceeding and the Motion in this district is proper pursuant to 28 U.S.C. §§ 1408 and 1409; and this Court having found that the relief requested in the Motion is in the best interests of the Debtor’s estate, its creditors, and other parties in interest; and this Court having found that the Debtor’s notice of the Motion was appropriate under the circumstances and no other notice need be provided; and this Court having reviewed the Motion and having heard the statements in support of the relief requested therein at a hearing before this Court (the “Hearing”); and this Court having determined that the legal and factual bases set forth in the Motion and at the Hearing establish just cause for the relief granted herein; and upon all of the proceedings had before this Court; and after due deliberation and sufficient cause appearing therefor, it is
HEREBY ORDERED THAT:
1. The Motion is GRANTED on an interim basis as set forth herein.
2. The Final Hearing, if required, on the Motion will be held on April 11, 2018 at 10:00 a.m. (prevailing Eastern time). Objections, if any, that relate to the Motion shall be filed and served so as to be actually received by the Debtor’s proposed counsel on or before April 3, 2018 at 4:00 p.m. (prevailing Eastern time). Any objection shall set forth in writing and with particularity the factual and legal basis of the objection. If no objections are filed to the Motion, the Court may enter the Final Order without further notice or hearing. 2

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 4 of 11
3. The Debtor is authorized, but not directed, to: (a) continue operating the Cash Management System, as described in the Motion; (b) honor its prepetition obligations related thereto; (c) maintain its existing Business Forms; and (d) continue to perform Intercompany Transactions in the ordinary course and with the consent of the DIP Administrative Agent in an aggregate amount not to exceed $25,000 on an interim basis, in each case subject to the limitations described in the Motion and this Interim Order.
4. The Debtor is further authorized, in its sole discretion, to: (a) continue to use, with the same account numbers, the Bank Accounts in existence as of the Petition Date, including those accounts identified on Exhibit C attached to the Motion; (b) use, in their present form, the Business Forms, as well as correspondence, checks and other documents related to the Bank Accounts existing immediately before the Petition Date and thereafter, without reference to the Debtor’s status as debtor in possession; provided that once the Debtor’s preprinted correspondence, Business Forms (including letterhead) and existing checks have been used, the Debtor shall, when reordering, require the designation “Debtor in Possession” and the corresponding bankruptcy case number on all such documents; provided further that, with respect to checks and letterhead which the Debtor or its agents print themselves, the Debtor shall begin printing the “Debtor in Possession” legend and the bankruptcy case number on such items within ten (10) days of the date of entry of this Order; (c) treat the Debtor’s existing Bank Accounts for all purposes as accounts of the Debtor as debtor in possession; (d) deposit funds in and withdraw funds from the Bank Accounts by all usual means, including checks, wire transfers, and other debits; (e) pay the prepetition Bank Fees; and (f) pay any ordinary course Bank Fees incurred in connection with the Debtor’s existing Bank Accounts, and to otherwise perform its obligations under the documents governing the Debtor’s existing Bank Accounts. 3

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 5 of 11
Any requirements by the United States Trustee or otherwise to open separate debtor-in¬possession accounts are waived, unless otherwise specified herein.
5. Each of the Banks is authorized to debit the Debtor’s accounts in the
ordinary course of business without need for further order of this Court for: (a) all checks, items, and other payment orders drawn on the Debtor’s accounts which are cashed at such Bank’s counters or exchanged for cashier’s checks by the payees thereof prior to the Bank’s receipt of notice of filing of this Chapter 11 Case; (b) all checks, automated clearing house entries, and other items deposited or credited to one of the Debtor’s accounts with such Bank prior to the commencement of this Chapter 11 Case which have been dishonored, reversed, or returned unpaid for any reason, together with any fees and costs in connection therewith, to the same extent the individual Debtor was responsible for such items prior to commencement of this Chapter 11 Case; and (c) all undisputed prepetition amounts outstanding as of the date hereof, if any, owed to any Bank as service charges for the maintenance of the Cash Management System.
6. All Banks at which the Debtor’s existing Bank Accounts are maintained are authorized to continue to maintain, service, and administer the Debtor’s existing Bank Accounts as accounts of the Debtor as debtor in possession, without interruption and in the ordinary course, and to receive, process, honor, and pay, to the extent of available funds, any and all checks, drafts, wires, credit card payments, and ACH transfers issued and drawn on the Debtor’s existing Bank Accounts after the Petition Date by the holders or makers thereof, as the case may be. For Banks at which the Debtor holds Bank Accounts that are party to a Uniform Depository agreement with the Office of the United States Trustee for the District of Delaware, within fifteen (15) days of the date of entry of this Order the Debtor shall (a) contact each Bank, (b) provide the Bank with the Debtor’s employer identification number and (c) identify each of 4

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 6 of 11
its Bank Accounts held at such Banks as being held by a debtor in possession in a bankruptcy case, and provide the case number.
7. All Banks provided with notice of this Interim Order maintaining any of the Debtor’s existing Bank Accounts shall not honor or pay any bank payments drawn on the listed Bank Accounts or otherwise issued before the Petition Date for which the Debtor specifically issues stop payment orders in accordance with the documents governing such Bank
Accounts.
8. In the course of providing cash management services to the Debtor, each of the Banks is authorized, without further order of this Court, to deduct the applicable fees from the appropriate accounts of the Debtor, and further, to charge back to the appropriate accounts of the Debtor any amounts resulting from returned checks or other returned items, including returned items that result from ACH transactions, wire transfers, or other electronic transfers of any kind, regardless of whether such items were deposited or transferred prepetition or postpetition and regardless of whether the returned items relate to prepetition or postpetition
items or transfers.
9. Subject to the terms set forth herein, any of the Debtor’s Banks may rely on the representations of the Debtor with respect to whether any check, item, or other payment order drawn or issued by the Debtor prior to filing of the Petition should be honored pursuant to this or any other order of this Court, and such Bank shall not have any liability to any party for relying on such representations by the Debtor as provided for herein.
10. Any Banks are further authorized to (a) honor the Debtor’s directions with respect to the opening and closing of any Bank Account and (b) accept and hold, or invest, the Debtor’s funds in accordance with the Debtor’s instructions; provided, however, that the 5

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 7 of 11
Debtor’s Banks shall not have any liability to any party for relying on such representations to the extent such reliance otherwise complies with applicable law.
11. The Debtor is authorized to open any new Bank Accounts or close any existing Bank Accounts as it may deem necessary and appropriate in its sole discretion; provided, however, that the Debtor gives notice within fifteen (15) days to the Office of the United States Trustee for the District of Delaware and any statutory committees appointed in the chapter 11 case; provided, further, however, that the Debtor shall open any such new Bank Account at banks that have executed a Uniform Depository Agreement with the Office of the United States Trustee for the District of Delaware, or at such banks that are willing to immediately execute such an agreement.
12. The Debtor’s time to comply with section 345(b) of the Bankruptcy Code with respect to any uncovered financial institutions is hereby extended for a period of thirty (30) days from the date of this Interim Order (the “Extension Period”), provided that such extension is without prejudice to the Debtor’s right to request a further extension of the Extension Period or the waiver of the requirements of section 345(b) of the Chapter 11 Case, including at the Final Hearing.
13. The Debtor is authorized to continue engaging in Intercompany Transactions in connection with the Cash Management System in the ordinary course of business and with the consent of the DIP Administrative Agent; provided, however, that there shall be no intercompany loans from the Debtor to any non-debtors, absent further order of the Court; and provided further that prior to the final order on this Motion, transfers from the Debtor to non-Debtor affiliates shall not exceed $25,000. 6

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 8 of 11
14. Notwithstanding the relief granted in this Interim Order and any actions taken pursuant to such relief, nothing in this Interim Order shall be deemed: (a) an admission as to the validity of any prepetition claim against a Debtor entity; (b) a waiver of the Debtor’s right to dispute any prepetition claim on any grounds; (c) a promise or requirement to pay any prepetition claim; (d) an implication or admission that any particular claim is of a type specified or defined in this Interim Order or the Motion; (e) a request or authorization to assume any prepetition agreement, contract, or lease pursuant to section 365 of the Bankruptcy Code; or (f) a waiver of the Debtor’s rights under the Bankruptcy Code or any other applicable law.
15. The contents of the Motion satisfy the requirements of Bankruptcy Rule
6003(b).
16. Notice of the Motion as provided therein shall be deemed good and sufficient notice of such Motion and the requirements of Bankruptcy Rule 6004(a) and the Local Rules are satisfied by such notice.
17. Notwithstanding Bankruptcy Rule 6004(h), the terms and conditions of this Interim Order are immediately effective and enforceable upon its entry.
18. The Debtor is authorized to take all actions necessary to effectuate the relief granted in this Interim Order in accordance with the Motion.
19. This Court retains exclusive jurisdiction with respect to all matters arising from or related to the implementation, interpretation, and enforcement of this Interim Order.
,2018 Wilmington, Delaware THE HONORABLE KEVIN CROSS UNITED STATES BANKRUPTCY JUDGE 7

Case 18-10518-KG    Doc 92-3    Filed 03/27/18    Page 9 of 11

DEBTOR’S BANK ACCOUNTS

Case 18-10518-KG Doc 92-3 Filed 03/27/18 Page 10 of 11
US Accounts - Held in name of Orexigen Therapeutics, Inc.
Legend:
= debtor entity bank account
= automatic transfer
= manual transfer
AR Lockbox Account (USD) Silicon Valley Bank Account XXXXXX1180 Collection account for customer payments Swept Daily General Checking Account (USD) Silicon Valley Bank Account XXXXXX6813 Disbursement account for funding payroll and operations Swept Daily As Necessary
Sweep Account (USD) Silicon Valley Bank Account XXXXXX3036 Holds excess cash invested in U.S. short-term Treasury and government securities
Holding Account (USD) US Bank Account XXXXXXXX4219 Holding account for excess cash and invested in short-term U.S. government securities Account managed by Wells Fargo

Case 18-10518-KG    Doc 92-3    Filed 03/27/18    Page 11 of 11

SCHEDULE OF RETAINERS PAID TO PROFESSIONALS

(This schedule is to include each Professional paid a retainer)