Attached files

file filename
EX-99.2 - EX-99.2 - Blueprint Medicines Corpbpmc_ex992.htm
EX-99.1 - EX-99.1 - Blueprint Medicines Corpbpmc_ex991pressrelease.htm

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 


 

FORM 8-K

 


 

CURRENT REPORT

Pursuant to Section 13 or 15(d) 

of the Securities Exchange Act of 1934

 

Date of Report (Date of Earliest Event Reported): November 29, 2016

 


 

Blueprint Medicines Corporation

(Exact name of registrant as specified in its charter)

 


 

 

 

 

 

 

Delaware

 

001-37359

 

26-3632015

(State or other jurisdiction

of incorporation)

 

(Commission File Number)

 

(I.R.S. Employer
Identification No.)

 

 

 

 

 

 

38 Sidney Street, Suite 200

Cambridge, Massachusetts

 

02139

(Address of principal executive offices)

 

(Zip Code)

 

 

Registrant’s telephone number, including area code: (617) 374-7580

 

(Former name or former address, if changed since last report)

 


 

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

 

Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)

Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)

Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))

Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

 

 


 

Item 8.01        Other Events.

On November 30, 2016, Blueprint Medicines Corporation (the “Company”) issued a press release announcing initial data from the dose escalation stage of its ongoing Phase 1 clinical trial evaluating BLU-285 for the treatment of advanced gastrointestinal stromal tumors. BLU-285 is an orally available, potent and highly selective inhibitor that targets D842V mutant PDGFRα and Exon 17 mutant KIT. The Company is presenting the data on Thursday,  December 1, 2016, in an oral presentation at the 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Munich, Germany (the “EORTC-NCI-AACR Symposium”). A copy of the press release is attached as Exhibit 99.1 to this Current Report on Form 8-K and incorporated herein by reference.

In addition, on November 29, 2016 at the EORTC-NCI-AACR Symposium, the Company presented data from the dose escalation stage of its ongoing Phase 1 clinical trial evaluating BLU-554 for the treatment of advanced hepatocellular carcinoma. BLU-554 is an orally available, potent and highly selective inhibitor that targets the kinase FGFR4. A copy of the poster presentation is attached as Exhibit 99.2 to this Current Report on Form 8-K and incorporated herein by reference.  

Item 9.01        Financial Statements and Exhibits.

(d) Exhibits.

 

 

 

Exhibit No.

 

Description

99.1

 

Press release issued by Blueprint Medicines Corporation on November 30, 2016

99.2

 

Poster presentation by Blueprint Medicines Corporation on November 29, 2016 at the EORTC-NCI-AACR Symposium

 

 

2


 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

 

 

 

 

 

 

BLUEPRINT MEDICINES CORPORATION

 

 

 

 

 Date: November 30, 2016

By:

/s/ Jeffrey W. Albers

 

 

Jeffrey W. Albers

 

 

Chief Executive Officer

 

 

3


 

EXHIBIT INDEX

 

 

 

 

Exhibit No.

 

Description

99.1

 

Press release issued by Blueprint Medicines Corporation on November 30, 2016

99.2

 

Poster presentation by Blueprint Medicines Corporation on November 29, 2016 at the EORTC-NCI-AACR Symposium

 

4