NephroGenex, Inc. - FORM 8-K - EX-99.1 - EXHIBIT 99.1

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55151/0001-13492201v1 IN THE UNITED STATES BANKRUPTCY COURT FOR THE DISTRICT OF DELAWARE ---------------------------------------------------------- In re: NEPHROGENEX, INC., Debtor.1 ---------------------------------------------------------- x : : : : : : : x Chapter 11 Case No. 16-11074 (KG) NOTICE OF FILING OF MONTHLY OPERATING REPORT FOR THE PERIOD OF JULY 1, 2016 THROUGH JULY 31, 2016 PLEASE TAKE NOTICE that, on August 23, 2016, the above-captioned debtor and debtor-in-possession (the “Debtor”) has filed with the United States Bankruptcy Court for the District of Delaware the Debtor’s Monthly Operating Report for the Period of July 1, 2016 through July 31, 2016, a copy of which is attached hereto as Exhibit A (the “Monthly Operating Report”). Dated: Wilmington, Delaware August 23, 2016 COLE SCHOTZ P.C. /s/ David R. Hurst David R. Hurst (I.D. No. 3743) 500 Delaware Avenue, Suite 1410 Wilmington, Delaware 19801 Telephone: (302) 652-3131 Facsimile: (302) 652-3117 – and – 1 The last four digits of the Debtor’s federal tax identification number are 5171. The mailing address for the Debtor is 3200 Beechleaf Court, Suite 900, Raleigh, NC 27604. Case 16-11074-KG Doc 134 Filed 08/23/16 Page 1 of 15

2 55151/0001-13492201v1 Jacob S. Frumkin 1325 Avenue of the Americas, 19th Floor New York, New York 10019 Telephone: (212) 752-8000 Facsimile: (212) 752-8393 Counsel for Debtor and Debtor-in-Possession Case 16-11074-KG Doc 134 Filed 08/23/16 Page 2 of 15

55151/0001-13492201v1 EXHIBIT A Monthly Operating Report Case 16-11074-KG Doc 134 Filed 08/23/16 Page 3 of 15

Case 16-11074-KG Doc 134 Filed 08/23/16 Page 4 of 15

NOTES TO THE MONTHLY OPERATING REPORT General Notes Debtor‐in‐Possession Financial Statements‐ The Debtor's financial statements and supplemental information contained herein are unaudited, preliminary, and may not comply with generally accepted accounting principles in the United States of America (“U.S. GAAP”) in all material respects. Accounting Standards Codification (“ASC”) 852‐10, Reorganizations, which incorporated the guidance in American Institute of Certified Public Accountants Statement of Position 90‐7, “Financial Reporting by Entities in Reorganization under the Bankruptcy Code,” (SOP 90‐7), is applicable to companies in chapter 11 and generally does not change the manner in which financial statements are prepared. It does require, however, that the financial statements for periods subsequent to the filing of the chapter 11 petition distinguish transactions and events that are directly associated with the reorganization from the ongoing operations of business. The Debtor's financial statements contained herein have been prepared in accordance with the guidance in ASC 852‐10. The unaudited financial statements have been derived from the books and records of the Debtor. This information, however, has not been subject to procedures that would typically be applied to financial information presented in accordance with U.S. GAAP, and upon the application of such procedures, the Debtor believes that the financial information could be subject to changes, and these changes could be material. The information furnished in this report includes primarily normal recurring adjustments, but does not include all of the adjustments that would be typically made in accordance with U.S. GAAP. The results of operations contained herein are not necessarily indicative of results that are expected from any other period or for the full year and may not necessarily reflect the combined results of operations, financial position and cash flows of the Debtor in the future. Liabilities Subject to Compromise‐ As a result of the chapter 11 filing, the payment of prepetition indebtedness is subject to compromise or other treatment under a plan of reorganization or liquidation. The determination of how liabilities will ultimately be settled and treated cannot be made until the Court approves a chapter 11 plan of reorganization or liquidation. Accordingly, the ultimate amount of such liabilities is not determinable at this time. Revenues, expenses, realized gains and losses and provisions for losses that can be directly associated with the reorganization and restructuring of the business must be reported separately as reorganization items in the Debtor's statement of operations. The Debtor's balance sheets, in addition, must distinguish pre‐petition liabilities subject to compromise from both those pre‐petition liabilities that are not subject to compromise and from post‐petition liabilities. Liabilities that may be affected by a plan of reorganization or liquidation must be reported at the amounts expected to be allowed, even if they may be settled for lesser amounts. In addition, cash provided by reorganization items must be disclosed separately in the Debtor's statement of cash flows. The amounts currently classified as liabilities subject to compromise are preliminary and may be subject to future adjustments depending on Court actions, further developments with respect to disputed claims, determinations of the secured status of certain claims, the values of any collateral securing such claims, rejection of executory contracts, continued reconciliation and other events. While in bankruptcy, the Debtor expects its financial results to continue to be volatile as asset impairments, asset dispositions, contract terminations and rejections and claims assessments may significantly impact the Debtor's financial statements. As a result, the Debtor's historical financial performance is likely not indicative of its financial performance after the date of the chapter 11 Filing. Notes to MOR‐1a Cash Disbursements Journal‐ The Debtor's cash disbursement journal is not included herein, however, a copy will be provided upon request. Notes to MOR‐4 Copies of IRS Form 6123 or Payment Receipt and Copies of Tax Returns Filed During Reporting Period‐No IRS Form 6123 or Payment Receipt or Tax Returns were filed during the reporting period. Postpetition Accounts Payable‐ The postpetition accounts payable reported for the reporting period represent open and outstanding trade vendor invoices that have been entered into the Debtor’s accounts payable system and do not include accruals for invoices not yet received or approved. Case 16-11074-KG Doc 134 Filed 08/23/16 Page 5 of 15

In re: NephroGenex, Inc. Case No. 16‐11074 (KG) Reporting Period: 7/01/2016 ‐ 7/31/2016 SCHEDULE OF CASH RECEIPTS AND DISBURSEMENTS BANK ACCOUNTS CURRENT MONTH Cumulative Filing To Date OPERATING Money Market ACTUAL ACTUAL CASH BEGINNING OF MONTH 4,292,197$ 25,033$ 4,317,230$ 4,636,083$ RECEIPTS PROFESSIONAL RETAINER REFUNDS ‐ ‐ ‐ 40,724 INSURANCE PREMIUM REFUNDS ‐ ‐ ‐ 25,310 COBRA PAYMENT FROM FORMER EMPLOYEE ‐ ‐ ‐ 1,919 INTEREST EARNED ON MONEY MARKET ACCOUNT ‐ 3 3 9 TOTAL RECEIPTS ‐$ 3$ 3$ 67,962$ DISBURSEMENTS NET PAYROLL (Including Employee Reimbursements)₁ 35,673 ‐ 35,673 109,547 PAYROLL TAXES (Employer and Employees) 21,100 ‐ 21,100 63,809 401k CONTRIBUTIONS (Employer and Employees) 2,302 ‐ 2,302 6,463 CURRENT EMPLOYEE BENEFITS (Health and HSA contribution) 5,929 ‐ 5,929 17,318 FORMER EMPLOYEE BENEFITS (Health and HSA contribution)₂ ‐ ‐ ‐ 12,055 RENT 9,893 ‐ 9,893 29,679 INSURANCE 2,603 ‐ 2,603 7,867 VENDOR PAYMENTS 39,280 ‐ 39,280 224,629 REORGANIZATION FEES 160,767 ‐ 160,767 192,992 TOTAL DISBURSEMENTS 277,547$ ‐$ 277,547$ 664,359$ NET CASH FLOW (277,547)$ 3$ (277,544)$ (596,397)$ CASH ‐ END OF MONTH 4,014,650$ 25,036$ 4,039,686$ 4,039,686$ DISBURSEMENTS FOR CALCULATING U.S. TRUSTEE QUARTERLY FEES: 277,547$ 664,359$ 5,657 PLUS: ESTATE DISBURSEMENTS MADE BY OUTSIDE SOURCES (i.e. from escrow accounts) ‐ ‐ TOTAL DISBURSEMENTS FOR CALCULATING U.S. TRUSTEE QUARTERLY FEES 277,547$ 658,702$ 3. This amount represents the pass‐through COBRA payments made to BCBSNC on behalf of former employees. EastWest Bank TOTAL DISBURSEMENTS LESS: PASS THROUGH COBRA PAYMENTS₃ 1. Net Payroll includes employee reimbursements in the amount of $589 for the period. 2. Former employee benefits including 1) health benefits paid and HSA contributions made on behalf of two former employees in connection with their severance agreements as well as 2) pass‐through COBRA payments made on behalf of former employees. FORM MOR-1 (04/07) Case 16-11074-KG Doc 134 Filed 08/23/16 Page 6 of 15

In re: NephroGenex, Inc. Case No: 16‐11074 (KG) Reporting Period: 7/01/2016 ‐ 7/31/2016 BANK RECONCILIATIONS Continuation Sheet for MOR‐1 Operating Money Market # # BALANCE PER BOOKS $4,014,650.27 $25,035.78 BANK BALANCE $4,027,764.39 $25,035.78 (+) DEPOSITS IN TRANSIT (ATTACH LIST) (‐) OUTSTANDING CHECKS (ATTACH LIST) $13,114.12 OTHER (ATTACH EXPLANATION) ADJUSTED BANK BALANCE * $4,014,650.27 $25,035.78 * Adjusted bank balance must equal balance per books DEPOSITS IN TRANSIT Date Amount Date Amount CHECKS OUTSTANDING Ck. # Amount Ch. # Amount 4192 $200.00 4233 $937.26 4234 $517.66 4235 $2,282.82 4236 $301.44 4237 $2,348.89 4238 $500.00 4239 $4,875.00 ACH $1,151.05 FORM MOR-1a (04/07) Case 16-11074-KG Doc 134 Filed 08/23/16 Page 7 of 15

In re: NephroGenex, Inc. 11819920 Case No. 16‐11074 (KG) Reporting Period: 7/01/2016 ‐ 7/31/2016 Year‐To‐Date Payor Number Date Fees Expenses Fees Expenses Kurtzman Carson Consultant April 30, 2016 to May 31, 2016 $32,225.24 NephroGenex, Inc. Wire 6/28/2016 $15,393 $16,832 $15,393 $16,832 Cassel Salpeter & Co., LLC April 30, 2016 to May 31, 2016 $37,854.00 NephroGenex, Inc. Wire 7/8/2016 $30,000 $6,000 $30,000 $6,000 Cole Schotz P.C. April 30, 2016 to May 31, 2016 $149,441.31 NephroGenex, Inc. Wire 7/8/2016 $118,199 $1,692 $118,199 $1,692 SCHEDULE OF PROFESSIONAL FEES AND EXPENSES PAID Amount ApprovedPayee Period Covered Check Amount Paid FORM MOR-1b (04/07) Case 16-11074-KG Doc 134 Filed 08/23/16 Page 8 of 15

Jul‐16 Cumulative Filing To Date Operating Expenses: Research & Development₁ 4,866$ 19,079$ Corporate Governance₂ 180,458$ 359,419$ Compensation & Benefits₃ 69,319$ 213,485$ Professional and Consultant Fees₄ 710$ 135,373$ Office, Telecommunication and Supplies 10,163$ 30,983$ Rent 9,992$ 29,975$ Dues and Subscriptions 972$ 3,881$ Depreciation 1,090$ 3,271$ Travel‐Related Expenses 40$ 866$ Prepetition Debt Paid ‐$ 602$ Total Operating Expenses 277,610$ 796,933$ Other Income/Expenses: Reorganization Expenses₅ 137,615$ 535,261$ Interest Expense (Income) (3)$ (9)$ Net Loss 415,222$ 1,332,185$ 2. Corporate Governance expenses consist of board of director fees, insurance and other governance services incurred during the period. 3. Compensation & Benefits consist of payroll, payroll taxes and employee benefits during the period. 4. Professional and Consultant fees consists of costs incurred with ordinary course professionals/consultants during the period. NephroGenex, Inc. Statement of Operations For the reporting period of July 1, 2016 to July 31, 2016 5. Reorganization expenses consist of fees incurred by professionals that are directly associated with the reorganization as well as U.S. Trustee fees owed during the period. Specifically, these professionals are Cole Schotz P.C., Cassel Salpeter & Co., LLC and Kurtzman Carson Consultants LLC. 1. Research & Development expenses consist of wind‐down activities associated with PYR‐311 incurred during the period. However, Research & Development expenses does not include an invoice for consulting fees received by the Debtor in the amount of $59,828.00, which the Debtor disputes. Case 16-11074-KG Doc 134 Filed 08/23/16 Page 9 of 15

Book Value on Petition Date Book Value at End of Current Reporting Month Assets April 30, 2016 July 31, 2016 Current Assets Cash and Cash Equivalents 4,611,056$ 4,014,650$ Restricted Cash 25,027 25,036 Prepaid Expenses and Other Assets₁ 2,768,947 2,477,826 Professional Retainers 246,806 204,082 Total Current Assets 7,651,836 6,721,594 Property and Equipment, net 37,061 33,790 Other Long‐Term Assets 9,534 9,534 Total Assets 7,698,430$ 6,764,918$ Liabilities and Stockholders' Equity (Deficit) Current Liabilities Accounts Payable₂ 9,821$ 41,768$ Accrued and Other Liabilities₃ 3,738 16,913 Accrued Compensation₄ 27,837 39,423 Reorganization Liability ‐ 342,268 Total Current Liabilities 41,395 440,372 Liabilities Subject To Compromise₅ 5,462,449 5,461,847 Deferred Rent 24,185 24,482 Total Liabilities 5,528,029 5,926,701 Common Stock 12,948 12,950 APIC 91,815,598 91,815,596 Retained Earnings (80,682,596) (80,682,596) Current Year Net Loss ‐ Pre‐Petition (8,975,548) (8,975,548) Current Year Net Loss ‐ Post‐Petition (1,332,184) Total Stockholders' Equity 2,170,401 838,217 Total Liabilities & Stockholders' Equity (Deficit) 7,698,430$ 6,764,918$ 2. Accounts Payable as of April 30, 2016 represents an invoice related to Debtor's May rental payment that is typically payable in advance. The May rental payment was paid on or about May 5, 2016 in the ordinary course of business. Accounts Payable as of the current reporting period represents post‐petition accounts payable. However, Accounts Payable as of the current reporting period does not include an invoice for consulting fees received by the Debtor in the amount of $59,828.00, which the Debtor disputes. 3. Accrued and Other Liabilities as of April 30, 2016 represents COBRA payments received from former employees for the month of May. The May COBRA payments for these former employees were paid on or about May 5, 2016 subsequent to the Interim Wage Order being entered by the Bankruptcy Court. Accrued and Other Liabilities as of the current reporting period represents post‐ petition Accrued and Other Liabilities. 4. Accrued Compensation represents accrued paid‐time‐off earned but not yet used or paid. The amounts as of April 30, 2016 represent pre‐petition amounts. The amounts as of the current reporting period represent pre‐petition amounts plus any incremental amounts earned during the post‐petition period. 5. Liabilities Subject To Compromise do not include contingent severance liabilities. NephroGenex, Inc. Balance Sheets 1. Prepaid Expenses and Other Assets consist of prepaid insurance (including D&O and clinical trial tail insurance), vendor deposits and advances in ordinary course of business. Case 16-11074-KG Doc 134 Filed 08/23/16 Page 10 of 15

In re: NephroGenex, Inc. Case No. 16‐11074 (KG) Reporting Period: 7/01/2016 ‐ 7/31/2016 STATUS OF POSTPETITION TAXES Beginning Amount Ending Tax Withheld or Amount Date Check No. Tax Liability Accrued Paid Paid or EFT Liability Federal State and Local Total Taxes SUMMARY OF UNPAID POSTPETITION DEBTS Attach aged listing of accounts payable. Number of Days Past Due Current 0‐30 31‐60 61‐90 Over 90 Total Accounts Payable₁ 35,620$ 4,640$ 1,508$ ‐$ 41,768$ Wages Payable Taxes Payable Rent/Leases‐Building Rent/Leases‐Equipment Secured Debt/Adequate Protection Payments Professional Fees Amounts Due to Insiders* Other:__________________________ Other:__________________________ Total Postpetition Debts 35,620$ 4,640$ 1,508$ ‐$ ‐$ 41,768$ 1. A majority of these amounts relate to services provided by the Debtor's ordinary course professionals and will be paid during the month of August. All postpetition taxes were current as of 7/31/2016 and paid in the ordinary course by the Debtor. All postpetition taxes were current as of 7/31/2016 and paid in the ordinary course by the Debtor. FORM MOR-4 (04/07) Case 16-11074-KG Doc 134 Filed 08/23/16 Page 11 of 15

In re: NephroGenex, Inc. Case No. 16‐11074 (KG) Reporting Period: 7/01/2016 ‐ 7/31/2016 ACCOUNTS RECEIVABLE RECONCILIATION AND AGING Accounts Receivable Reconciliation Amount NOT APPLICABLE Accounts Receivable Aging Amount NOT APPLICABLE DEBTOR QUESTIONNAIRE Must be completed each month Yes No 1. Have any assets been sold or transferred outside the normal course of business X this reporting period? If yes, provide an explanation below. 2. Have any funds been disbursed from any account other than a debtor in possession X account this reporting period? If yes, provide an explanation below. 3. Have all postpetition tax returns been timely filed? If no, provide an explanation X below. 4. Are workers compensation, general liability and other necessary insurance X coverages in effect? If no, provide an explanation below. 5. Has any bank account been opened during the reporting period? If yes, provide X documentation identifying the opened account(s). If an investment account has been opened provide the required documentation pursuant to the Delaware Local Rule 4001‐3. FORM MOR-5 (04/07) Case 16-11074-KG Doc 134 Filed 08/23/16 Page 12 of 15

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NephroGenex, Inc. - FORM 8-K - EX-99.1 - EXHIBIT 99.1 - August 23, 2016

Attached files

NephroGenex, Inc. Reports