Attached files

file filename
EX-99.2 - EX-99.2 - Onconova Therapeutics, Inc.a2228844zex-99_2.htm
EX-99.7 - EX-99.7 - Onconova Therapeutics, Inc.a2228844zex-99_7.htm
EX-99.6 - EX-99.6 - Onconova Therapeutics, Inc.a2228844zex-99_6.htm
EX-99.5 - EX-99.5 - Onconova Therapeutics, Inc.a2228844zex-99_5.htm
EX-99.4 - EX-99.4 - Onconova Therapeutics, Inc.a2228844zex-99_4.htm
EX-99.3 - EX-99.3 - Onconova Therapeutics, Inc.a2228844zex-99_3.htm
EX-99.1 - EX-99.1 - Onconova Therapeutics, Inc.a2228844zex-99_1.htm
EX-4.5 - EX-4.5 - Onconova Therapeutics, Inc.a2228844zex-4_5.htm
S-1 - S-1 - Onconova Therapeutics, Inc.a2228844zs-1.htm

QuickLinks -- Click here to rapidly navigate through this document


Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

        We consent to the reference to our firm under the caption "Experts" in the Registration Statement (Form S-1 No. 333-          ) and related Prospectus of Onconova Therapeutics, Inc. and to the incorporation by reference therein of our report dated March 28, 2016, with respect to the consolidated financial statements of Onconova Therapeutics, Inc. included in its Annual Report (Form 10-K) for the year ended December 31, 2015, filed with the Securities and Exchange Commission.

 

/s/ Ernst & Young LLP

Philadelphia, Pennsylvania
June 1, 2016




QuickLinks

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM