Exhibit 99.1

BIOMED REALTY TRUST REPORTS FIRST QUARTER 2015 FINANCIAL RESULTS

Strong Gross Leasing Continues with 780,800 Square Feet During the Quarter

SAN DIEGO, Calif. – April 28, 2015 – BioMed Realty Trust, Inc. (NYSE: BMR), the leading real estate company focusing on life sciences, today reported funds from operations (FFO) and core FFO (CFFO) per diluted share of $0.41 for the first quarter ended March 31, 2015, driven by over three million square feet of gross leasing over the past four quarters.

First Quarter Highlights

“As demonstrated by our strong first quarter results, the pace of innovation continues to drive demand for high-quality research environments in the core innovation districts where our deep and experienced team continues to execute and where we are well-positioned to grow with our valued tenant partners,” said Alan Gold, Chairman, President and Chief Executive Officer of BioMed Realty. “Sustained leasing demand is driving rent growth across all of our key markets, and we believe that this trend will continue through 2015.”

FFO, CFFO and AFFO are supplemental non-GAAP financial measures used in the real estate industry to measure and compare the operating performance of real estate companies. A complete reconciliation containing adjustments from GAAP net income available to common stockholders to FFO, CFFO and AFFO and definitions of terms are included at the end of this release.

First Quarter 2015 Portfolio Update

During the quarter ended March 31, 2015, the company executed 49 leasing transactions representing 780,800 square feet, contributing to an operating portfolio leased percentage on a weighted-average book value basis of 90.7%. With the addition of the new i3 development in San Diego, the active new construction portfolio now comprises eight projects totaling nearly two million square feet, which was 71.9% pre-leased at quarter end.

First quarter leasing comprised:

Subsequent to the end of the first quarter, the company executed a new 15-year lease with Alnylam Pharmaceuticals for approximately 295,000 square feet at 675 West Kendall Street in Cambridge, Massachusetts, which is currently leased to Vertex Pharmaceuticals until April 2018.

During the first quarter, the company acquired the 307 Westlake Avenue North building in Seattle’s South Lake Union innovation district for $89.7 million. The building is approximately 116,200 square feet of Class A laboratory and office space, which is 99% leased to four tenants, including approximately 84,800 square feet which serves as the headquarters and research facility for Seattle Biomedical Research Institute.

“Our development pipeline will enable us to capitalize on the continued demand for well-located research space in thriving core innovation districts,” noted John Bonanno, BioMed Realty’s Executive Vice President of Development and Investments. “Our two million square feet under development is 72% pre-leased with tenant relationships across the spectrum of life science and health care communities. And starting construction this quarter on our i3 project in San Diego puts us well ahead of our competition in being able to meet strong market demand in a supply constrained market.”

First Quarter 2015 Financial Results

Total revenues for the first quarter were approximately $178.0 million, compared to approximately $168.9 million for the same period in 2014. Rental revenues for the first quarter were approximately $117.5 million.

CFFO and FFO, calculated in accordance with standards established by NAREIT, for the first quarter were $0.41 per diluted share. These amounts include:

AFFO for the quarter was $0.36 per diluted share. The company reported net income attributable to common stockholders for the quarter of approximately $17.3 million, or $0.08 per diluted share.

Subsequent to the end of the quarter, the company realized additional gains totaling $43.8 million, net of an allocation of income attributable to noncontrolling interests, from the sale of an equity investment in a single life science company.

Earnings Guidance

The company’s updated 2015 guidance for net income per diluted share and FFO (and CFFO) per diluted share are set forth and reconciled below. Projected net income per diluted share and FFO (and CFFO) per diluted share are based upon estimated, weighted-average diluted common shares outstanding of approximately 208.4 million and 209.3 million, respectively.

Key assumptions underlying the company’s updated projections of 2015 net income per diluted share and FFO (and CFFO) per diluted share are included in the company’s Supplemental Operating and Financial Data for the three months ended March 31, 2015 available on the company’s website. In addition, the company has posted an updated slide presentation for the first quarter on its website under the title “Investor Presentation – April 2015”.

The company’s 2015 FFO and CFFO estimates reflect the impact of previously announced new investments and dispositions, including the acquisition of the 307 Westlake Avenue North building in Seattle and commencement of the i3 development in San Diego in the first quarter. The foregoing estimates do not include the effect of any other revenue or income (or losses) that might arise from lease terminations, other than the impact of lease termination revenue totaling $16.2 million recorded during the three months ended March 31, 2015, which had the net effect of increasing the 2015 FFO and CFFO estimate by $0.08 per diluted share. These estimates also do not include the effect of any investment gains or losses other than gains recorded during the first quarter and additional gains realized since March 31, 2015 from the sale of investments in life science companies totaling $54.8 million, net of an allocation of income attributable to noncontrolling interests, which have the effect of increasing the 2015 FFO and CFFO estimate by $0.26 per diluted share.

The company continues to target new investment opportunities, including acquisitions and new development projects; however, the company’s 2015 FFO and CFFO estimates do not reflect the impact of any other future new investments (acquisitions or development), or related financing activity, as the impact of such investments may vary significantly based on the nature of these investments, timing and other factors.

The foregoing estimates are forward-looking and reflect management’s view of current and future market conditions, including certain assumptions with respect to leasing activity, rental rates, occupancy levels, interest rates, financings, acquisitions, dispositions, development and redevelopment and the amount and timing of acquisitions, development and redevelopment activities. The company’s actual results may differ materially from these estimates.

Supplemental Information

Supplemental operating and financial data are available in the Investor Relations section of the company’s website at www.biomedrealty.com.

Teleconference and Webcast

BioMed Realty will conduct a conference call and webcast at 10:00 a.m. Pacific Time (1:00 p.m. Eastern Time) on Wednesday, April 29, 2015 to discuss the company’s financial results and operations for the quarter. The call will be open to all interested investors through a live audio web cast at the Investor Relations section of the company’s web site at www.biomedrealty.com, which will include an online slide presentation to accompany the call, or live by calling (800) 446-2782 (domestic) or (847) 413-3235 (international) with call ID number 39527085. The complete webcast will be archived for 30 days on both web sites. A telephone playback of the conference call will also be available from 12:30 p.m. Pacific Time on Wednesday, April 29, 2015 until midnight Pacific Time on Monday, May 4, 2015 by calling (888) 843-7419 (domestic) or (630) 652-3042 (international) and using access code 39527085#.

About BioMed Realty Trust

BioMed Realty, with its trusted expertise and valuable relationships, delivers optimal real estate solutions for biotechnology and pharmaceutical companies, scientific research institutions, government agencies and other entities involved in the life science industry. BioMed Realty owns or has interests in properties comprising approximately18 million rentable square feet. Additional information is available at www.biomedrealty.com. Follow us on Twitter @biomedrealty.

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 based on current expectations, forecasts and assumptions that involve risks and uncertainties that could cause actual outcomes and results to differ materially. These risks and uncertainties include, without limitation: general risks affecting the real estate industry (including, without limitation, the inability to enter into or renew leases, dependence on tenants’ financial condition, and competition from other developers, owners and operators of real estate); adverse economic or real estate developments in the life science industry or the company’s target markets; risks associated with the availability and terms of financing, the use of debt to fund acquisitions, developments and other investments, and the ability to refinance indebtedness as it comes due; failure to maintain the company’s investment grade credit ratings with the ratings agencies; failure to manage effectively the company’s growth and expansion into new markets, or to complete or integrate acquisitions and developments successfully; reductions in asset valuations and related impairment charges; risks and uncertainties affecting property

development and construction; risks associated with tax credits, grants and other subsidies to fund development activities; risks associated with downturns in foreign, domestic and local economies, changes in interest rates and foreign currency exchange rates, and volatility in the securities markets; ownership of properties outside of the United States that subject the company to different and potentially greater risks than those associated with the company’s domestic operations; risks associated with the company’s investments in loans, including borrower defaults and potential principal losses; potential liability for uninsured losses and environmental contamination; risks associated with security breaches and other disruptions to the company’s information technology networks and related systems; risks associated with the company’s potential failure to qualify as a REIT under the Internal Revenue Code of 1986, as amended, and possible adverse changes in tax and environmental laws; and risks associated with the company’s dependence on key personnel whose continued service is not guaranteed. For a further list and description of such risks and uncertainties, see the reports filed by the company with the Securities and Exchange Commission, including the company’s most recent annual report on Form 10-K and quarterly reports on Form 10-Q. The company disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

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(Financial Tables Follow)

BIOMED REALTY TRUST, INC.

CONSOLIDATED BALANCE SHEETS

(In thousands, except share data)

BIOMED REALTY TRUST, INC.

CONSOLIDATED STATEMENTS OF INCOME

(In thousands, except share data)

BIOMED REALTY TRUST, INC.

CONSOLIDATED FUNDS FROM OPERATIONS

(In thousands, except share data)

(Unaudited)

Our FFO and CFFO attributable to common shares and partnership and LTIP units and a reconciliation to net income for the three months ended March 31, 2015 and 2014 was as follows:

Our AFFO attributable to common shares and partnership and LTIP units and a reconciliation of CFFO to AFFO for the three months ended March 31, 2015 and 2014 was as follows:

We present funds from operations, or FFO, core funds from operations, or CFFO, and adjusted funds from operations, or AFFO, attributable to common shares and partnership and LTIP units because we consider them important supplemental measures of our operating performance and believe they are frequently used by securities analysts, investors and other interested parties in the evaluation of REITs, many of which present FFO, CFFO and AFFO when reporting their results.

FFO is intended to exclude GAAP historical cost depreciation and amortization of real estate and related assets, which assumes that the value of real estate assets diminishes ratably over time. Historically, however, real estate values have risen or fallen with market conditions. Because FFO excludes depreciation and amortization unique to real estate, gains and losses from property dispositions and extraordinary items, it provides a performance measure that, when compared year over year, reflects the impact to operations from trends in occupancy rates, rental rates, operating costs, development activities and interest costs, providing perspective not immediately apparent from net income. We compute FFO in accordance with standards established by the Board of Governors of the National Association of Real Estate Investment Trusts, or NAREIT. As defined by NAREIT, FFO represents net income (computed in accordance with GAAP), excluding gains (or losses) from sales of property, impairment charges on depreciable real estate, real estate related depreciation and amortization (excluding amortization of loan origination costs) and after adjustments for unconsolidated partnerships and joint ventures.

We calculate CFFO by adding acquisition-related expenses to FFO. We calculate AFFO by adding to CFFO: (a) non-cash revenues and expenses, (b) recurring capital expenditures and second generation tenant improvements, and (c) leasing commissions.

Our computation of FFO, CFFO and AFFO may differ from the methodology for calculating FFO, CFFO and AFFO utilized by other equity REITs and, accordingly, may not be comparable to such other REITs. Further, FFO, CFFO and AFFO do not represent cash flow available for management’s discretionary use because of needed capital replacement or expansion, debt service obligations, or other commitments and uncertainties. FFO, CFFO and AFFO should not be considered as an alternative to net income (loss) (computed in accordance with GAAP) as an indicator of our financial performance or to cash flow from operating activities (computed in accordance with GAAP) as an indicator of our liquidity, nor is it indicative of funds available to fund our cash needs, including our ability to pay dividends or make distributions. FFO, CFFO and AFFO should be considered only as supplements to net income computed in accordance with GAAP as measures of our operations.