UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d)

OF THE SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported): March 10, 2015

Carter Validus Mission Critical REIT, Inc.

(Exact Name of Registrant as Specified in Its Charter)

4890 West Kennedy Blvd.

Suite 650

Tampa, Florida 33609

(Address of principal executive offices)

(813) 287-0101

(Registrant’s telephone number, including area code)

N/A

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Effective March 10, 2015, the board of directors, or the Board, of Carter Validus Mission Critical REIT, Inc., or the Company, appointed Michael Seton to serve as President of the Company to replace John E. Carter, who resigned from his position as President concurrent with Mr. Seton’s appointment. Mr. Carter remains the Chairman of the Board and Chief Executive Officer of the Company.

Mr. Seton, age 42, is the President and a member of the Investment Management Committee of Carter/Validus Advisors, LLC, the Company’s advisor, and the President of the Company’s sponsor, Carter/Validus REIT Investment Company, LLC. He also serves as the President and a member of the Investment Committee of Carter Validus Advisors II, LLC and the President of Carter Validus REIT Management Company II, LLC, both of which are affiliates of the Company. Mr. Seton is responsible for day-to-day oversight of the business operations, including acquisitions, underwriting, capital markets and asset management for the Company. In addition, Mr. Seton served as the Executive Vice President and head of the Capital Markets Group of Carter & Associates, L.L.C., or Carter & Associates, one of the principals of the Company’s sponsor, from September 2009 to December 2010, prior to the Securities and Exchange Commission declaring the Company’s offering effective.

Mr. Seton has more than 20 years of real estate and investment finance experience. From 1996 until joining Carter & Associates, Mr. Seton worked for Eurohypo AG (including its predecessor organizations) in New York, New York. At Eurohypo AG, Mr. Seton was a Managing Director and Division Head in the Originations Group, leading a team of twelve professionals in the origination, structuring, documentation, closing and distribution of real estate financings for private developers and owners, REITs, and real estate operating companies (REOCs). Real estate finance transactions in which Mr. Seton was involved included both on and off-balance sheet executions, including senior debt and mezzanine financings. Mr. Seton has been directly involved in over $32 billion in financings for real estate clients, including high profile transactions such as the recapitalization of the Chrysler Building and the General Motors Building, both of which are located in New York, New York, Merchandise Mart in Chicago, Illinois, construction financing for 15 Central Park West in New York, New York, several Ritz-Carlton hotels throughout the United States, and many office developments in major U.S. cities. While at Eurohypo AG, Mr. Seton’s clients included Millennium Partners, Tishman Speyer Properties, Vornado Realty Trust, Carter & Associates, Boston Properties and Goldman Sachs. Mr. Seton obtained a Bachelor of Science in Economics from Vanderbilt University in Nashville, Tennessee in 1994.

Mr. Seton did not enter into an employment agreement with the Company in connection with his appointment as President of the Company, and the appointment of Mr. Seton as President of the Company was not made pursuant to any arrangement or understanding between Mr. Seton and any other person. Mr. Seton has not had any direct or indirect material interests in any transaction with the Company or to which the Company is a party or in any currently proposed transaction with the Company or to which the Company is a party.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.