Exhibit 99.1

BIND Therapeutics Reports Fourth Quarter and Full Year 2014 Financial Results

– Enrollment Underway in Phase 2 iNSITE 1 Trial for BIND-014 in KRAS Mutant or Squamous Histology Non-Small Cell Lung Cancer; Initial Clinical Data Reported as Early as 4^th Quarter 2015 -

– Management to host conference call today at 8:30 a.m. EDT –

CAMBRIDGE, Mass., March 11, 2015 — BIND Therapeutics, Inc. (NASDAQ: BIND), a clinical-stage nanomedicine platform company developing targeted and programmable therapeutics called Accurins^TM, today reported financial results for the fourth quarter and year-ended December 31, 2014.

“2014 was a defining year for BIND as we made considerable progress in transitioning the company from a platform technology to a drug development company,” said Andrew Hirsch, BIND’s newly appointed acting president and chief executive officer. “We believe that data from the BIND-014 clinical trials validate our therapeutic platform and demonstrated that BIND-014 improved efficacy, compared to historical docetaxel controls, using a lower dose and with meaningful improvements in the toxicity profile. We’re extremely encouraged by the progress we have made on our collaboration programs and anticipate an IND application for our first collaboration compound with AstraZeneca by the middle of 2015. With our recently strengthened balance sheet, we are positioned to execute our operating plan through and beyond critical inflection points in the BIND-014 clinical program, potentially initiating phase 3 trials as early as the first half of 2016, and in our collaborations.”

The Company’s expected upcoming milestones include the following:

BIND-014

BIND’s clinical development plan for BIND-014 is informed by positive data from its phase 2 trial in NSCLC presented at the 26^th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in November 2014. The results of this phase 2 study demonstrated substantial clinical activity of BIND-014 as monotherapy in advanced 2^nd line NSCLC patients, with 15 percent partial response rate (n= 40; 5 confirmed, 1 unconfirmed), a disease control rate (> 6 weeks) of 63 percent and meaningful reduction of docetaxel-related toxicities at a 20 percent lower dose than Taxotere^® in a sicker patient population than most phase 2 studies in this indication. Data from the phase 2 trial also showed a confirmed objective response rate of 22 percent (n=9) in patients with KRAS mutant NSCLC; one KRAS mutant NSCLC partial response was also seen in the phase 1 trial with BIND-014, yielding a combined total response rate of 30 percent (n=10). Prolonged (>6 weeks) disease control was also noted in 66 percent of patients with KRAS mutant NSCLC. Results from the phase 2 trial also suggested meaningful differentiation in NSCLC patients with squamous histology when compared to historical docetaxel results. BIND-014 results presented at EORTC-NCI-AACR demonstrated a disease control rate (>6 weeks) of 66 percent and overall survival of 11.1 months (n=9) in NSCLC patients with squamous histology.

“We believe data from the phase 2 trial of BIND-014 in non-small cell lung cancer showed clear evidence that it has the potential to provide meaningful clinical benefit in two easily identified forms of the disease with high unmet need that affects more than 40 percent of patients with advanced metastatic disease,” said Hagop Youssoufian, M.Sc., M.D., chief medical officer at BIND. “Based on these results, we have initiated iNSITE 1, a global, two-tiered phase 2 trial in KRAS mutant or squamous histology NSCLC subpopulations. Additionally, we are initiating iNSITE 2, a phase 2 trial with BIND-014 in cholangiocarcinoma, cervical cancer, bladder cancer, and head and neck cancers. These are cancers where we have seen signals of anti-tumor activity with BIND-014 in our phase 1 clinical trial and, while there is evidence that these cancers are taxane sensitive, there are no approved therapies for these patients.”

Fourth Quarter 2014 Financial Results

Revenue for the fourth quarter of 2014 was $3.0 million, compared to $2.1 million for the fourth quarter of 2013. The year-over-year increase in revenue was primarily due to higher reimbursable research and development activities, primarily for our AstraZeneca collaboration.

Research and development expenses totaled $8.0 million for the fourth quarter of 2014, compared to $7.4 million for the fourth quarter of 2013. The increase was primarily driven by headcount growth to support the development of BIND’s internal pipeline and collaborations.

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General and administrative expenses totaled $4.2 million for the fourth quarter of 2014, compared to $2.7 million for the fourth quarter of 2013. The increase was primarily due to higher compensation expenses and external consulting expenses.

Net loss for the fourth quarter of 2014 was $8.5 million, compared to a net loss of $8.1 million for the fourth quarter of 2013.

Full Year 2014 Financial Results

Revenue for the year ended December 31, 2014 was $10.4 million, compared to $10.9 million for the year ended December 31, 2013. The year-over-year decrease in revenue was primarily due to a reduction in up-front license fee revenue recognized that was partially offset by an increase in reimbursable research and development activities we performed under our collaboration agreements, principally for AstraZeneca, Pfizer and Roche.

Research and development expenses were $28.9 million for the year ended December 31, 2014, compared to $24.4 million for the year ended December 31, 2013. This increase was primarily driven by headcount growth to support the development of BIND’s internal pipeline and collaborations.

General and administrative expenses were $15.1 million for the year ended December 31, 2014, compared to $13.4 million for the year ended December 31, 2013. The increase was primarily due to higher compensation expenses, external consulting expenses and other expenses principally related to operating as a public company since the fourth quarter of 2013.

Net loss for the year ended December 31, 2014 was $32.5 million, compared to a net loss of $27.7 million for the year ended December 31, 2013.

Cash, cash equivalents and short-term investments were approximately $41 million as of December 31, 2014.

Financial Expectations

The Company expects that its cash, cash equivalents and short-term investments as of December 31, 2014, in addition to the capital raised in the first quarter of 2015 through its amended credit facility with Hercules Technology III, L.P. and its February 10, 2015 offering of common stock and warrants, will fund operating expenses and capital expenditure requirements into mid-2016. This expectation is based on the Company’s current operating plans and research and development funding that it expects to receive under its existing collaborations, but excludes any potential milestone payments.

Recent Business Developments

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2014 Collaboration Developments

Conference Call Information

BIND’s management team will host a conference call and audio webcast today at 8:30 a.m. ET to discuss the fourth quarter and full year 2014 results and provide a corporate update. To access the conference call, please dial (877) 312-5844 (domestic) or (253) 237-1152 (international) at least five minutes prior to the start time and refer to conference ID 88372910.

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An audio webcast of the call will also be available on the Investors & Media section of the Company’s website www.bindtherapeutics.com. An archived webcast will be available on the Company’s website approximately two hours after the event and will be available for 30 days.

About BIND Therapeutics

BIND Therapeutics is a clinical-stage nanomedicine platform company developing a pipeline of Accurins, its novel targeted therapeutics designed to increase the concentration and duration of therapeutic payloads at disease sites while reducing exposure to healthy tissue. BIND is leveraging its Medicinal Nanoengineering platform to develop a pipeline of Accurins targeting hematological and solid tumors and has a number of strategic collaborations with biopharmaceutical companies to develop Accurins in areas of high unmet need. BIND’s lead drug candidate, BIND-014, is a prostate-specific membrane antigen (PSMA) -targeted Accurin that contains docetaxel, a clinically-validated and widely-used cancer chemotherapy drug. BIND-014 is currently in development for the treatment of non-small cell lung cancer, or NSCLC, in patients with KRAS mutations or squamous histology. In addition, BIND plans to initiate clinical trials with BIND-014 in cervical, bladder, head and neck and cholangio cancers in 2015. BIND is also advancing BIND-510, its second PSMA-targeted Accurin drug candidate containing vincristine, a potent microtubule inhibitor with dose limiting peripheral neuropathy in its conventional form, through important preclinical studies to position it for an Investigational New Drug (IND) application filing with the U.S. Food and Drug Administration (FDA) in 2016. Lastly, BIND is developing Accurins designed to inhibit PLK1 and KSP, both of which BIND believes are promising anti-mitotic targets that have been limited in the clinic due to myelotoxicity prior to reaching therapeutic doses.

BIND has announced ongoing collaborations with Pfizer Inc., AstraZeneca AB, F. Hoffmann-La Roche Ltd. and Merck & Co., or Merck (known as Merck Sharp & Dohme outside the United States and Canada), to develop Accurins based on their proprietary therapeutic payloads and targeting ligands.

For more information, please visit the Company’s web site at www.bindtherapeutics.com.

Forward-Looking Statements Disclaimer

This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including statements regarding BIND-014, including without limitation, our belief that data from our clinical trials validate our platform, clinical benefits of BIND-014, our expectations regarding the iNSITE 1 and iNSITE 2 clinical trials of BIND-014, and BIND-014’s potential; BIND-510, including without limitation, statements regarding our plan for an Investigational New Drug filing in 2016; opportunities regarding our nanomedicine platform; our collaboration agreements with Pfizer, Merck and AstraZeneca; our belief that AstraZeneca will file an IND application by mid-2015; the sufficiency of our cash, cash equivalents and short-term investments; our transition from a platform technology company to a drug development company; and our expected upcoming milestones.

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These forward-looking statements are based on management’s current expectations. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, the following: the fact that the Company has incurred significant losses since its inception and expects to incur losses for the foreseeable future; the Company’s need for additional funding, which may not be available; raising additional capital may cause dilution to its stockholders, restrict its operations or require it to relinquish rights to its technologies or drug candidates; the Company’s limited operating history; the terms of the Company’s credit facility place restrictions on its operating and financial flexibility; failure to use and expand its medicinal nanoengineering platform to build a pipeline of drug candidates and develop marketable drugs; the early stage of the Company’s development efforts with only one drug candidate in clinical development; failure of the Company or its collaborators to successfully develop and commercialize drug candidates; clinical drug development involves a lengthy and expensive process, with an uncertain outcome; delays or difficulties in the enrollment of patients in clinical trials; serious adverse or unacceptable side effects or limited efficacy observed during the development of the Company’s drug candidates; inability to maintain any of the Company’s collaborations, or the failure of these collaborations; the Company’s reliance on third parties to conduct its clinical trials and manufacture its drug candidates; the Company’s inability to obtain required regulatory approvals; any conclusion by the FDA that BIND-014 does not satisfy the requirements for approval under the Section 505(b)(2) regulatory approval pathway; the fact that a fast track or breakthrough therapy designation by the FDA for the Company’s drug candidates may not actually lead to a faster development or regulatory review or approval process; the inability to obtain orphan drug exclusivity for drug candidates; failure to obtain marketing approval in international jurisdictions; any post-marketing restrictions or withdrawals from the market; effects of recently enacted and future legislation; failure to comply with environmental, health and safety laws and regulations; failure to achieve market acceptance by physicians, patients, or third-party payors; failure to establish effective sales, marketing and distribution capabilities or enter into agreements with third parties with such capabilities; effects of substantial competition; unfavorable pricing regulations, third-party reimbursement practices or healthcare reform initiatives; product liability lawsuits; failure to retain key executives and attract, retain and motivate qualified personnel; difficulties in managing the Company’s growth; risks associated with operating internationally, including the possibility of sanctions with respect to our operations in Russia; the possibility of system failures or security breaches; failure to obtain and maintain patent protection for or otherwise protect our technology and products; effects of patent or other intellectual property lawsuits; the eligibility of a significant portion of the Company’s total outstanding shares to be sold into the market, which could cause the market price of its common stock to drop significantly; increased costs as a result of operating as a public company; and any securities class action litigation. These and other important factors discussed under the caption “Risk Factors” in our Annual Report on Form 10-K filed with the Securities and Exchange Commission, or SEC, on March 11, 2015, and our other reports filed with the SEC could cause actual results to differ

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materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management’s estimates as of the date of this press release. While we may elect to update such forward-looking statements at some point in the future, we disclaim any obligation to do so, even if subsequent events cause our views to change. These forward-looking statements should not be relied upon as representing our views as of any date subsequent to the date of this press release.

BIND THERAPEUTICS, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited)

(Amounts in thousands, except share and per share data)

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BIND THERAPEUTICS, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited)

(Amounts in thousands, except share data)

Media:

Jeff Boyle

347-247-5089

media@bindtherapeutics.com

Investors:

Tom Baker

617-532-0624

investors@bindtherapeutics.com

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