Exhibit 99.3

FEDERICO PIGNATELLI

August 8, 2014

BY ELECTRONIC MAIL

BIOLASE, Inc. Board of Directors

4 Cromwell

Irvine, California 92618

Gentlemen:

I am in receipt of Mr. Carroll’s email transmitted on August 7, 2014 referencing the subject “BIOLASE – Letter of Resignation” and attaching the 8-K filed by BIOLASE on August 7, 2014 with respect to the resignations of both Dr. Nemoy and me from the BIOLASE Board (the “8-K Report”). As Mr. Carroll’s email accurately states, “Per clause (a)(3) of Item 5.02, [I] have the opportunity to furnish BIOLASE as promptly as possible with a letter addressed to BIOLASE stating whether [I] agree with the statements made by BIOLASE in response to Item 5.02 and, if not, stating the respects in which [I] do not agree”. I am providing this letter pursuant to Item 5.02 with full reservation of all rights to further respond once BIOLASE corrects the defect in the 8-K Report as noted below.

Item 502(a)(1)(iii) of Form 8-K requires that BIOLASE disclose in the 8-K Report “a brief description of the circumstances representing the disagreement that the registrant believes caused, in whole or in part, the director’s resignation, refusal to stand for re-election or removal”. No such description is contained in the 8-K Report rendering the 8-K Report incomplete. My letter of resignation delineates numerous circumstances that formed the basis for the disagreement that led to my resignation and refusal to stand for reelection – yet not a single one of those circumstances has been addressed. Instead, the 8-K Report contains a summary statement, not responsive to Item 502(a)(1)(iii) that, “the Company does not agree with many of the statements contained in [my] letter and has disclosed related background information in the Recent Developments section of BIOLASE’s proxy statement for the 2014 annual meeting”. Clearly, both my fellow BIOLASE stockholders and I are entitled to know which of my statements BIOLASE agrees with and which BIOLASE disagrees with. This will permit me, and all BIOLASE stockholders, to understand that which is in dispute and that which is not in dispute and “the circumstances representing the disagreement,” as applicable Federal securities laws require. It will further provide me with the opportunity provided for under Federal securities laws, specifically Item 502(a) (3) (i) of Form 8-K, to have an “opportunity to furnish the [Company]. . . . . . . . with a letter addressed to the [Company] stating whether [I] agree or disagree with the statement made by the [Company] in response to [Item 5.02]”.

It would appear that BIOLASE’s selective and incomplete 8-K Report is a calculated effort to deprive all BIOLASE stockholders of a fundamental understanding of that which has transpired and me of the opportunity to respond, as Federal securities laws clearly provide for, to BIOLASE’s position on the facts and circumstances surrounding my resignation.

To facilitate a corrective filing by BIOLASE, the issues underlying the disagreements leading to my resignation and refusal to stand for reelection, as described in more detail in my letter of resignation, include:

I look forward to prompt receipt of a copy of a corrective Form 8-K filing by BIOLASE at which time I will, as appropriate, amend and/or supplement this letter which is provided pursuant to Item 5.02(a)(3)(ii) of Form 8-K.

Respectfully submitted,

Federico Pignatelli