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8-K - 8-K - PFIZER INCd716893d8k.htm
EX-99.3 - EX-99.3 - PFIZER INCd716893dex993.htm
EX-99.2 - EX-99.2 - PFIZER INCd716893dex992.htm
EX-99.5 - EX-99.5 - PFIZER INCd716893dex995.htm
EX-99.7 - EX-99.7 - PFIZER INCd716893dex997.htm
EX-99.4 - EX-99.4 - PFIZER INCd716893dex994.htm
EX-99.8 - EX-99.8 - PFIZER INCd716893dex998.htm
EX-99.1 - EX-99.1 - PFIZER INCd716893dex991.htm
Pfizer Announcement
Related to AstraZeneca
April 28, 2014
Exhibit 99.6


Introduction
Chuck Triano
Senior Vice President,
Investor Relations


Forward-Looking Statements and
Non-GAAP Financial Information
Our discussions during this conference call will include forward-looking statements.  Actual results
could differ materially from those projected in the forward-looking statements. The factors that could
cause actual results to differ are discussed in the press release regarding the possible combination
issued by Pfizer today, Pfizer’s 2013 Annual Report on Form 10-K and in our reports on Form 10-Q
and Form 8-K.  Nothing contained herein shall be deemed to be a forecast, projection or estimate of
the future financial performance of Pfizer, AstraZeneca or the combined business following
completion of any possible transaction unless otherwise stated.
Also, the discussions during this conference call will include certain financial measures that were not
prepared in accordance with U.S. generally accepted accounting principles (GAAP). Reconciliations
of those non-U.S. GAAP financial measures to the most directly comparable U.S. GAAP financial
measures can be found in the SEC filings referenced above.
This presentation should be read in conjunction with the Rule 2.4 Possible Offer Announcement
made by Pfizer on April 28, 2014.
This presentation is provided for informational purposes only and is neither an offer to purchase nor a
solicitation of an offer to sell shares of Pfizer or AstraZeneca. Subject to future developments, Pfizer
may file a registration statement and/or tender offer documents with the U.S. Securities and
Exchange Commission (the "SEC") in connection with the possible combination. Pfizer and
AstraZeneca shareholders should read those filings, and any other filings made by Pfizer with the
SEC in connection with the possible combination, as they will contain important information. Those
documents, if and when filed, as well as Pfizer's other public filings with the SEC, including the SEC
filings
referenced
above,
may
be
obtained
without
charge
at
the
SEC’s
website
at
www.sec.gov
and
at
Pfizer's
website
at
www.pfizer.com
in
the
"Investors—SEC
Filings"
section.
Certain
other
materials
related to the possible combination will be available at Pfizer’s website, pursuant to the requirements
of the UK Takeover Code.


Agenda
Potential Offer Background & Summary
Pfizer Overview
Potential Pfizer + AstraZeneca Combination
Next Steps
4


Prepared Remarks
Ian Read
Chairman and Chief Executive Officer


Potential Offer Background &
Summary


Background
Pfizer previously submitted a preliminary, non-binding indication of interest to AstraZeneca’s
Board
In January, Pfizer’s proposal included a combination of cash and shares which represented an
indicative value of £46.61 ($76.62) per share (based on Pfizer’s closing share price of $30.52 on
January 3, 2014 and the exchange rate of $1.00:£0.6083).  This proposal represented a premium of
approximately 30% to AstraZeneca’s closing share price of £35.86 on January 3, 2014.
Intent to combine both companies under a new UK-incorporated holding company
Limited high-level discussions followed
AstraZeneca
declined
to
pursue
negotiations
and
discussions
were
discontinued
on
January
14,
2014
Pfizer attempted to renew discussions on April 26, 2014, but AstraZeneca again declined to engage
Transaction, if proposed and consummated, would allow AstraZeneca shareholders to become
significant shareholders in the combined company enabling participation in future potential value
creation
Possible Transaction would be aligned with Pfizer’s strategy
Pfizer will remain disciplined in terms of its approach to capital allocation
7
Pfizer is reconsidering its options with respect to AstraZeneca and seeking to engage in
discussions with AstraZeneca regarding a possible merger transaction
Possible combination could further enhance ability for value creation for shareholders of both
companies
In light of recent market developments, Pfizer contacted AstraZeneca seeking to renew discussions
in
order
to
develop
a
proposal
that
could
be
recommended
by
both
companies
to
their
shareholders


Why This Is The Right Time
Pfizer has strong standalone operating and financial momentum
New commercial structure driving strong operating performance, financial focus and a clear
vision towards value creation
Pfizer in a strong position to make a proposal that delivers:
An attractive premium for AstraZeneca shareholders
Improved opportunity for potential sustained future value creation with risk that is more
diversified than AstraZeneca’s standalone prospects
Substantial value to both Pfizer and AstraZeneca shareholders
8
Potential combination with AstraZeneca aligns with Pfizer’s operating structure in both
the commercial and research organizations
Notable potential opportunities to strengthen research, collaboration and innovation to
discover and develop new therapies to better serve patients in need
Envision potential to strengthen further key therapeutic areas such as Cardiovascular,
Immunology and Inflammation and Oncology
New commercial structure drives focused business development activity targeted to
create value for shareholders


Why Potential Offer Should Be Highly Compelling for
AstraZeneca Shareholders
Potential to realize a significant premium
Significant premium to the undisturbed AstraZeneca share price as of April 17, 2014
Substantial cash payment
Via execution on integration
Via a high quality product pipeline
Via go-forward capital structure flexibility
Strong pro forma financial profile
Significant operating expense leverage across both organizations
Enhanced capital flexibility for investment and shareholder returns
9
Opportunity to share in Pfizer value upside over medium / long-term


Why the Potential Combination Would Bring Benefits to
Pfizer
Would enable acceleration of our business strategy and strengthen competitive position
Would enhance global offerings for Innovative businesses while also creating a stronger research
platform in key areas and increasing new product launch opportunities
Would
increase
global
reach
and
portfolio
breadth
of
Established
Pharma
business
and
would
have
potential to increase strength and consistency of future cashflow generation
Stronger Emerging Markets footprint and better ability to bring products to market globally for the
benefit of patients and stakeholders
Attractive financial profile to drive potential significant value creation for all shareholders
Expected
to
be
accretive
to
Pfizer’s
adjusted
diluted
EPS
1
in
the
first
full
year
following
the 
combination
and
to
accelerate
EPS
growth
going
forward
2
Anticipated realization of significant synergies
Structured to achieve an efficient tax structure for combined operations and capital allocation
Expected to generate strong and consistent cash flow supporting both appropriate levels of
10
1)
“Adjusted
Income”
and
its
components
and
“Adjusted
Diluted
Earnings
Per
Share
(EPS)”
are
defined
as
reported
U.S.
generally
accepted
accounting
principles (GAAP) net income and its components and reported diluted EPS excluding purchase accounting adjustments, acquisition-related costs,
discontinued operations and certain significant items.
2) This should not be taken as a statement regarding  Pfizer's expectations for its earnings per share for 2014 or subsequent periods. Nothing contained
herein shall be deemed to be a forecast, projection or estimate of the future financial performance of Pfizer, AstraZeneca or the combined business
following completion of any transaction unless otherwise stated.
reinvestment into the business and significant shareholder return
Combination would strengthen both Innovative and Established businesses and improve
flexibility to unlock further value in the future


Pfizer Overview


12
Pfizer  Profile
manufacturing
sites worldwide (as of
4Q’13)
Revenue in 2013
countries
in which Pfizer
sells products
products with sales >$1
billion in 2013
R&D partner institutions
of Cash Flow from
Operations in 2013
colleagues around the
globe (as of 3/31/2014)
to shareholders through
dividends and share
repurchases in 2011-2013


13
From Advil to Zithromax…
Our Medicines, Vaccines and Consumer Health Products Help
Billions of Patients Every Year


New Commercial Structure
New Commercial Structure Better Positions Pfizer for Long-Term Success
Announced internal separation of our commercial and management structure into three
businesses effective at the start of fiscal 2014
Global Innovative Pharma
Geno Germano, Group President
Vaccines, Oncology and
Consumer Healthcare
Albert Bourla, Group President
Global Established Pharma
John Young, Group President
Inflammation/Immunology
CV/Metabolic
Neuroscience
Pain
Rare Diseases
Men’s/Women’s Health
Vaccines
Oncology
Consumer Healthcare
LOE Products
Biosimilars
EP/EM Collaborations
Mylan in Japan
Hisun in China
Teuto in Brazil
Generally includes products that are
expected to have exclusivity beyond
2015
Includes LOE products and generally the
mature patent-protected products that are
expected to lose exclusivity through 2015
Includes businesses with different
operating models and distinct
specializations
14


Proven Track Record of Strong Integration
15
Extensive
integration
experience
to
help
drive
shareholder
value
creation
Long history of strong integration of transformational business combinations
Prior examples of Pharmacia and Wyeth
Wyeth example of strong cost rationalization experience
Wyeth-related synergy targets of $4B from the combined companies
Exceeded Wyeth synergy targets
Best-of-the-best of both organizations
Key senior leadership of Pfizer from legacy Pfizer / Wyeth / other businesses
Focus on early integration planning
Quick
decision
making
and
broad
communication
to
ensure
swift
execution
e.g.,
senior leaders decided within 3 months of Wyeth integration planning


Potential Pfizer +
AstraZeneca Combination


Strategic Rationale for Combination of Pfizer and
AstraZeneca
17
Established Pharma
Business
Expect positive growth driven by leading Innovative businesses
operating at a global scale
Complementary strategic fit across multiple key therapeutic areas with
enhanced global offerings
Steady stream of potential new product launches anticipated over
coming years
Strong combined R&D organization and pipeline to support growth
Strong
pro-forma
company
profile
anticipate
positive
growth
and
sustainable
cashflows to optimize portfolios and return capital to shareholders
Increased scale and portfolio breadth of combined Established business to
maximize potential of portfolios
Would improve strength and consistency of cashflow generation 
More attractive profile and flexibility for any future business options
Strong
global
footprint
and
enhanced
opportunities
in
developing
markets
Innovative Businesses


Strategic Rationale
Complementary Innovative Portfolios
Vaccines
Prevnar
MnB vaccine
FluMist
FluMist-
Quadrivalent
Oncology
Sutent
Xalkori
Inlyta
Bosulif
Torisel
Palbociclib
Faslodex
Iressa
Caprelsa
Moxetumomab
Olaparib
Selumetinib
AZD-9291
Consumer
Health
Advil
Caltrate
Centrum
ChapStick
Emergen-C
Imedeen
Nexium OTC
Robitussin
Inflammation
& Immunology
Xeljanz
Enbrel
Lesinurad
Brodalumab
Cardiovascular
/ Metabolics
Eliquis
Chantix
PCSK9
Brilinta
Onglyza
Bydureon
Forxiga
Myalept
Epanova
Roxadustat
Neuro / Pain
Lyrica (ex-EU)
Embeda
Flector
Remoxy
ALO-02
Naloxegol
Rare Diseases
& Other
Specialty Care
Genotropin
Benefix
Refacto
Rebif
Rapamune
Elelyso
Synagis
Women’s &
Men’s Health
Viagra (US)
Duavee
Toviaz
Viviant
Pfizer
AstraZeneca
Pfizer
AstraZeneca
18
Complementary attractive
portfolios across multiple
key therapeutic areas
Innovative leadership at a
global scale
Strong combined Oncology,
Vaccines and Specialty
segments with greater
critical mass
Exciting combined
Cardiovascular and
Immunology/Inflammation
franchises
Complementary fit for
Diabetes franchise with
Pfizer primary care strength
Note: Phase 3 and registration
programs in italics; Only includes
select commercial and
development programs; Excludes
respiratory and infectious disease
assets (included as part of GEP)
Innovative
biopharma
leadership
driving
strong
potential
value
creation
Vaccines, Oncology, Consumer
Health (VOC)
Global Innovative Pharma
(GIP)


Strategic Rationale
Complementary Innovative Pipelines, Strengthens Key TAs
19
Vaccines                    
Oncology
Palbociclib
PF-03446962
PF-05212384
PF-04449913
PD-0325901
PF-03084014
PF-05082566
PF-06263507
PF-0643922
Moxetumomab
Olaparib
Selumetinib
AZD-9291
Tremelimumab
AZD-4547
MEDI-551
AZD-1775
MEDI-4736
AMP-514
MEDI-6469
AZD-5363
AZD-2014
MEDI-573
Inflammation
& Immunology
PD-0360324
PF-00547659
PF-04171327
PF-04236921
PF-05285401
PF-06473871
PH-797804
Brodalumab
Lesinurad
Mavrilimumab
MEDI-2070
MEDI-546
MEDI-7183
Sifalimumab
RDEA3170
Cardiovascular
/ Metabolics
Bococizumab
PF-00489791
PF-04634817
PF-04937319
PF-05175157
Epanova
Roxadustat
AZD-1722
AZD-4901
Neuro / Pain
Remoxy
ALO-02
Tanezumab
PF-02545920
PF-04360365 
PF-05212377
Naloxegol
AZD-3241
AZD-5213
Rare Diseases
& Other
Specialty Care
Tafamidis
Rivipansel
AZD-5847
Pfizer
AstraZeneca
Pfizer
AstraZeneca
Strong combined pipeline
driving potential innovative
growth
Diversifies risk away from
individual binary events
Limits future need to go
outside organization to
augment pipeline
Steady stream of
anticipated innovative new
product launches
Potentially synergistic in
key areas such as
Oncology, CV/Metabolics
Exciting combined pipeline with potential clinical synergies
Note: Phase 3 and registration
programs in italics; Only includes
select development programs;
Excludes respiratory and infectious
disease assets (included as part of
GEP)
Vaccines, Oncology, Consumer
Health (VOC)
Global Innovative Pharma
(GIP)
MnB vaccine
Staph A vaccine


Strategic Rationale 
Complementary Established Portfolios
Increased critical mass for market access and cost
efficiencies
Enhanced presence and infrastructure across emerging
markets
Development and regulatory capabilities to unlock
opportunities for product lifecycle
Rapid response distribution and reliable supply of high
quality, competitive cost products
Strong cashflow anticipated for reinvestment as well as
return of capital to shareholders
Sustainable franchises and potential growth opportunities
to maintain strong cashflow profile
Flexibility to invest in pipeline across primary care,
specialty, biosimilars
20
Scale and Breadth to Maximize Potential
of Established Portfolios
Maximizing
the
potential
of
mature
product
portfolios
strong
and
sustainable
cashflows, well-positioned for future business options
Primary &
Specialty
Care Assets
Lipitor, Celebrex,
Viagra (ex-US), Revatio,
Lyrica (EU), Pristiq,
Aricept, Spiriva, Caduet,
Detrol, Inspra, Vfend,
Zyvox, Tygacil,
Xalabrands, Geodon,
EpiPen, Premarin
Symbicort
Pulmicort
Crestor
Seroquel XR
Zoladex
Arimidex
Casodex
Merrem
Zinforo
Biosimilars
Monoclonal antibodies
Growth
initiatives /
Pipeline
Solid Oral Dose, Sterile
Injectibles, Branded
Value Offering (Hisun,
Teuto, Mylan)
Quillivant
Benralizumab
Tralokinumab
PT003 / PT001
CAZ-AVI
CXL
Other
Respiratory
Pipeline
Legacy
Brands
Norvasc, Cardura,
Zoloft, Neurontin,
Camptosar, Aromasin,
Medrol, Sulperazon,
Sermion, Ativan,
Protonix, Effexor,
Xanax, etc
Prilosec
Atacand
Toprol
Seloken
Seroquel
Nexium
Global Established Products
(GEP)
Pfizer
AstraZeneca
Note: Phase 3 and registration programs
in italics; Only includes select commercial
and development programs


Next Steps


Next Steps
Pfizer would like to negotiate a possible combination on a friendly basis
Hope to continue discussions with AstraZeneca
Begin engagement with other key stakeholders of both companies
Pfizer may either announce a firm offer or confirm that it will not be making an offer
Deadline can be extended with the agreement of AstraZeneca and with Takeover
Panel consent
If Pfizer announces a firm offer, Pfizer would move ahead with its offer and need to
obtain appropriate regulatory consents and shareholder approvals
Continue to be focused on Pfizer shareholder value creation and will be highly
disciplined on price
22
UK
Takeover
Code
provides
28
day
window
after
today’s
announcement


Q&A Session
April 28, 2014