Exhibit 99.1

Vocera Reports Fourth Quarter and Full-Year 2012 Results

SAN JOSE, Calif., February 27, 2013 — Vocera Communications, Inc. (NYSE: VCRA), a provider of mobile communication solutions focused on addressing critical communication challenges facing hospitals, today announced results for its fourth quarter and full year ended December 31, 2012.

Revenue for the quarter was $27.0 million, an increase of 24% compared to $21.7 million in the fourth quarter of 2011. For the fourth quarter of 2012, GAAP net income was $0.8 million, or $0.03 per diluted share, compared to a net loss of $0.2 million, or $(0.07) per diluted share, in the fourth quarter of 2011. Non-GAAP net income was $2.6 million for the fourth quarter of 2012, or $0.10 per diluted share, which compares to non-GAAP net income of $0.6 million or $0.03 per diluted share, for the fourth quarter of 2011. A reconciliation of GAAP to non-GAAP financial measures is provided in the schedules included below.

Revenue for the full year 2012 was $101.0 million, an increase of 27% compared to $79.5 million in 2011. For full year 2012, GAAP net income was $2.9 million, or $0.08 per diluted share, compared to a net loss of $2.5 million, or $(0.74) per diluted share, in 2011. Non-GAAP net income was $9.6 million for 2012, or $0.38 per diluted share, which compares to non-GAAP net income of $1.4 million or $0.08 per diluted share, for 2011. A reconciliation of GAAP to non-GAAP financial measures is provided in the schedules included below.

“We are very pleased with our fourth quarter results and our financial performance during our first year as a public company. We made good progress across all five of our growth strategies and believe we are well positioned for 2013 and beyond. In addition, our profitability continued to expand during 2012 and we are increasing our long-term profitability target. Contract wins with key healthcare national accounts, as well as in our Mobility business towards the end of the year, are also quite exciting,” commented Bob Zollars, Vocera Chairman and Chief Executive Officer.

Fourth Quarter 2012 Results

New National Accounts

Long-term Profitability Targets

Organizational Update

2013 Guidance

For the full year 2013, we are introducing revenue guidance of between $120 million and $130 million. We expect GAAP earnings per share between a loss of $0.10 and a profit of $0.09, non-GAAP earnings per share between $0.33 and $0.51, and non-GAAP Adjusted EBITDA between $12 million and $17 million. Our full year 2013 non-GAAP guidance excludes estimated stock compensation expense of $10.5 million to $11.0 million and estimated amortization of intangibles of approximately $0.7 million. Non-GAAP earnings per share guidance is based on a fully diluted share count of 27.3 million shares for the full year 2013 and expected income tax of $0.8 million.

For the first quarter of 2013, Vocera expects revenues between $23 million and $25 million, GAAP loss per share between $0.08 and $0.13, non-GAAP earnings between a loss of $1.2 million and breakeven, non-GAAP earnings per share between a loss of $0.05 and $0.00, and non-GAAP Adjusted EBITDA between a loss of $0.7 million and earnings of $0.5 million. Our first quarter 2013 non-GAAP guidance excludes stock compensation expense of $1.7 million and amortization of intangibles of $0.2 million. Non-GAAP earnings per share guidance is based on a fully diluted share count of 24.4 million shares for the first quarter 2013. Income tax for the first quarter of 2013 is expected to be immaterial.

Conference Call Information

The Company will conduct a conference call at 2:00 p.m. (Pacific), or 5:00 p.m. (Eastern), today, February 27, 2013. To participate in the Company’s live conference call, please dial 800-320-2978 or for international callers please dial 617-614-4923. The conference passcode is 72632406. You may also participate in the live webcast by visiting the Investors section of the Company’s web site at www.vocera.com. A replay will be available from Wednesday, February 27^th through Wednesday, March 6^th at 888-286-8010 or 617-801-6888 for international callers, by using the access code 50245619. A webcast replay will also be archived on the Company’s website.

About Vocera Communications

Vocera provides mobile communication solutions addressing critical communication challenges facing hospitals today. We help our customers improve patient safety and satisfaction, and increase hospital efficiency and productivity through our Voice Communication, Secure Messaging and Care Transition solutions. Exclusively endorsed by the American Hospital Association, the Vocera solutions are installed in more than 800 hospitals and healthcare facilities worldwide. The company is headquartered in San Jose, Calif., with offices in Tennessee, Canada and the United Kingdom. For more information, visit www.vocera.com.

Vocera and the Vocera logo are registered trademarks of Vocera Communications, Inc. All other product, trademark, company or service names mentioned in this press release are the property of their respective owners.

Forward Looking Statements

Statements in this press release that are not strictly historical in nature are forward-looking statements within the meaning of the U.S. federal securities laws, including statements regarding future events such as our expected operating results for the full year, as well as the performance of our Voice Communication solution, the successful execution of our business opportunities and the future financial performance of our company. These forward-looking statements are based on limited information currently available to Vocera and our management’s expectations that are inherently subject to change and involve a number of risks and uncertainties. Actual events or results may differ materially from those in any forward-looking statement due to various factors, including but not limited to our ability to maintain profitability; the demand for our Voice Communication solution in the healthcare market; our lengthy and unpredictable sales cycle; our ability to offer high-quality services and support for our solutions, to acquire the sole and limited source hardware and software components of our solutions, to obtain the required capacity and product quality from our contract manufacturer, to develop and introduce new solutions and features to existing solutions and to manage our growth; and the other factors described in Vocera’s final prospectus for its public offering filed with the Securities and Exchange Commission (“SEC”) on September 7, 2012 and Vocera’s other filings with the SEC. Vocera’s SEC filings are available on the Investors section of our company’s web site at www.vocera.com. The financial and other information contained in this press release should be read in conjunction with the financial statements and notes thereto included in Vocera’s filings with the SEC. Vocera’s operating results for the fourth quarter and year ended December 31, 2012 are not necessarily indicative of Vocera’s operating results for any future periods. This press release speaks only as of its date. Vocera assumes no obligation to update the information in this press release, to revise any forward-looking statements or to update the reasons actual events or results could differ materially from those anticipated in forward-looking statements.

Use of Non-GAAP Financial Information

This press release contains financial measures that are not calculated in accordance with U.S. generally accepted accounting principles (“GAAP”). Our management evaluates our company’s results and makes operating decisions using various GAAP and non-GAAP measures. In addition to Vocera’s GAAP results, we also consider non-GAAP gross margin, non-GAAP operating expenses, non-GAAP net income, and non-GAAP earnings per diluted share. We also present Adjusted EBITDA, a non-GAAP measure that we reconcile to net income. These non-GAAP measures should not be considered as a substitute to gross margin, operating expenses, net income, earnings per diluted share, or any other financial measure derived in accordance with GAAP. We present the non-GAAP measures because we consider them to be important supplemental information for our investors for analyzing Vocera’s performance, core operating results and trends. Investors are encouraged to review the reconciliation of non-GAAP financial measures to their most directly comparable GAAP measures included with this press release.

Our non-GAAP gross margin, non-GAAP operating expenses, non-GAAP net income, and non-GAAP earnings per diluted share as well as Adjusted EBITDA are exclusive of certain items to facilitate management’s review of the comparability of Vocera’s core operating results on a period to period basis because such items are not related to Vocera’s ongoing core operating results as viewed by management. We define our “core operating results” as those revenues recorded in a particular period and the expenses incurred within that period that directly drive operating income in that period. Management uses these non-GAAP financial measures in making operating decisions because, in addition to meaningful supplemental information regarding operating performance, the measures give us a better understanding of how we should invest in research and development, fund infrastructure growth and evaluate the effectiveness of marketing strategies. In calculating the above non-GAAP results, management specifically adjusted for the following excluded items:

a) Stock-based compensation expense impact. We recognize equity plan-related compensation expenses, which represent the fair value of all share-based payments to employees, including grants of employee stock options as non-GAAP adjustments in each period.

b) Amortization of acquired intangibles. We acquired certain companies in 2010 and booked intangible assets related to these acquisitions. The amortization of these acquisition related costs is excluded from non-GAAP net income because it is not related to ongoing controllable management decisions and because it is non-cash in nature.

c) Stock warrant revaluation expenses. This is a non-cash expense as a result of preferred warrants outstanding that have to be revalued each quarter. We believe the comparisons of ongoing operations should exclude effects of such revaluations.

Management adjusts for the above items because management believes that, in general, these items possess one or more of the following characteristics: their magnitude and timing is largely outside of Vocera’s control; they are unrelated to the ongoing operation of the business in the ordinary course; they are unusual and we do not expect them to occur in the ordinary course of business; or they are non-operational, or non-cash expenses involving stock option grants.

We believe that the presentation of these non-GAAP financial measures is warranted for several reasons:

1) Such non-GAAP financial measures provide an additional analytical tool for understanding Vocera’s financial performance by excluding the impact of items which may obscure trends in the core operating results of the business;

2) These non-GAAP financial measures facilitate comparisons to the operating results of other companies commonly compared to Vocera, which use similar financial measures to supplement their GAAP results, thus enhancing the perspective of investors who wish to utilize such comparisons in their analysis of our performance; and

3) These non-GAAP financial measures are employed by Vocera’s management in its own evaluation of performance and are utilized in financial and operational decision making processes, such as budget planning and forecasting.

Set forth below are additional reasons why share-based compensation expense is excluded from our non-GAAP financial measures:

i) While share-based compensation constitutes an ongoing and recurring expense of Vocera, it is not an expense that requires cash settlement by Vocera. We therefore exclude these charges for purposes of evaluating core operating results. Thus, our non-GAAP measurements are presented exclusive of stock-based compensation expense to assist management and investors in evaluating our core operating results.

ii) We present share-based payment compensation expense in our reconciliation of non-GAAP financial measures on a pre-tax basis because the exact tax differences related to the timing and deductibility of share-based compensation are dependent upon the trading price of Vocera’s common stock and the timing and exercise by employees of their stock options. As a result of these timing and market uncertainties the tax effect related to share-based compensation expense would be inconsistent in amount and frequency and is therefore excluded from our non-GAAP results.

As stated above, we present non-GAAP financial measures because we consider them to be important supplemental measures of performance. However, non-GAAP financial measures have limitations as an analytical tool and should not be considered in isolation or as a substitute for Vocera’s GAAP results. In the future, we expect to incur expenses similar to certain of the non-GAAP adjustments described above and expect to continue reporting non-GAAP financial measures excluding such items. Some of the limitations in relying on non-GAAP financial measures are:

Pursuant to the requirements of SEC Regulation G, a detailed reconciliation between Vocera’s non-GAAP and GAAP financial results is set forth in the financial tables at the end of this press release. Investors are advised to carefully review and consider this information strictly as a supplement to the GAAP results that are contained in this press release and in Vocera’s SEC filings.

Contact:

Bob East

Westwicke Partners

443-213-0502

bob.east@westwicke.com

Vocera Communications, Inc.

Consolidated statements of operations

(Unaudited)

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Consolidated balance sheets

(Unaudited)

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Reconciliation of GAAP to Non-GAAP

(In thousands, except per share data, unaudited)

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Reconciliation of GAAP to Non-GAAP

(In thousands, except per share data, unaudited)

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Non-GAAP income adjusting items

(In thousands, unaudited)

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Non-GAAP income adjusting items

(In thousands, unaudited)

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Adjusted EBITDA