UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

Pursuant to Section 13 or 15(d) of the

Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): May 17, 2012

Sykes Enterprises, Incorporated

(Exact name of registrant as specified in its charter)

Registrant’s telephone number, including area code: (813) 274-1000

(Former name or former address if changed since last report.)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

Four proposals described fully in the Sykes Enterprises, Incorporated (the “Company”) 2012 Proxy Statement were presented for approval at the Company’s 2012 Annual Meeting of Shareholders (the “Annual Meeting”) held on May 17, 2012. As of the record date, 43,419,788 shares of common stock were outstanding and entitled to vote at the Annual Meeting. At the Annual Meeting 41,282,674 shares of common stock were represented in person or by proxy; therefore, a quorum was present.

The shareholders of the Company voted on the following four matters:

Proposal 1: Election of Directors

There were two Class III director positions up for election. The following persons were nominated and elected to serve as directors of the Company until the 2015 Annual Meeting of Shareholders: Charles E. Sykes and William J. Meurer. The voting results for each nominee were as follows:

Proposal 2: Advisory Vote to Approve Executive Compensation

The proposal to approve, on a non-binding, advisory basis, the compensation of the Company’s named executive officers, as disclosed in the 2012 Proxy Statement, received the following votes:

Proposal 3: Approval of Amendments to the Sykes Enterprises, Incorporated 2004 Non-Employee Director Fee Plan

The proposal to approve amendments to the Company’s 2004 Non-Employee Director Fee Plan, as disclosed in the 2012 Proxy Statement, received the following votes:

Proposal 4: Ratification of the Appointment of Independent Registered Public Accounting Firm

The proposal to ratify the appointment of Deloitte & Touche LLP as the Company’s independent registered public accounting firm to audit the consolidated financial statements of the Company for the year ending December 31, 2012 and the effectiveness of the Company’s internal control over financial reporting as of December 31, 2012 and express an opinion thereon, as disclosed in the 2012 Proxy Statement, received the following votes:

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SIGNATURE

Pursuant to the requirements of the Securities and Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: May 18, 2012

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