Attached files

file filename
EXCEL - IDEA: XBRL DOCUMENT - DURECT CORPFinancial_Report.xls
10-K - FORM 10-K - DURECT CORPd274047d10k.htm
EX-32.1 - CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350 - DURECT CORPd274047dex321.htm
EX-31.2 - RULE 13A-14(A) SECTION 302 CERTIFICATION - DURECT CORPd274047dex312.htm
EX-32.2 - CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350 - DURECT CORPd274047dex322.htm
EX-31.1 - RULE 13A-14(A) SECTION 302 CERTIFICATION - DURECT CORPd274047dex311.htm
EX-23.1 - CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM - DURECT CORPd274047dex231.htm
EX-10.67 - LEASE TERMINATION AGREEMENT - DURECT CORPd274047dex1067.htm
EX-10.68 - AMENDMENT TO COMMERCIAL LEASE - DURECT CORPd274047dex1068.htm

Exhibit 12.1

COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES

The following table sets forth our ratio of earnings to fixed charges for each of the periods indicated (in thousands):

 

     Year Ended December 31,  
     2011     2010     2009     2008     2007  

Earnings:

          

Net loss

   $ (18,765 )   $ (22,898 )   $ (30,288 )   $ (43,907 )   $ (24,339 )

Fixed charges

     828        805        934        1,636        3,456   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Total Earnings

   $ (17,937 )   $ (22,093 )   $ (29,354 )   $ (42,271 )   $ (20,883 )
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Fixed Charges:

          

Interest expense

   $ 46      $ 6      $ 36      $ 789      $ 2,625   

Portion of rent expense representative of interest

     782        799        898        847        831   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Total Fixed Charges

   $ 828      $ 805      $ 934      $ 1,636      $ 3,456   
  

 

 

   

 

 

   

 

 

   

 

 

   

 

 

 

Ratio of Earnings to Fixed Charges(1)

     —          —          —          —          —     

 

(1) For purposes of computing the ratio of earnings to fixed charges, earnings consist of net loss plus fixed charges. Fixed charges consist of interest expense, amortization of debt expense and discount or premium related to indebtedness, whether expensed or capitalized, and that portion of rental payments under operating leases we believe to be representative of interest. Earnings were insufficient to cover fixed charges for these periods. The amount of the coverage deficiency was $18,765, $22,898, $30,288, $43,907, and $24,339 for the years ended December 31, 2011, 2010, 2009, 2008, and 2007, respectively.