UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

FORM 8-K

CURRENT REPORT

PURSUANT TO SECTION 13 OR 15(d) OF THE

SECURITIES EXCHANGE ACT OF 1934

Date of Report (Date of earliest event reported): February 29, 2012 (February 28, 2012)

(Exact name of registrant as specified in its charter)

(Address of principal executive offices, including zip code)

Registrant’s telephone number, including area code: (860) 298-4500

(Former name or former address, if changed since last report)

Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below):

On February 28, 2012, SS&C Technologies, Inc. (the “Company”), a wholly-owned subsidiary of SS&C Technologies Holdings, Inc., entered into a definitive Asset Purchase Agreement (the “Purchase Agreement”) with Thomson Reuters (Markets) LLC (“Thomson Reuters”). Pursuant to the Purchase Agreement, the Company will acquire the assets of Thomson Reuter’s PORTIA^® business (the “PORTIA Business”) for a purchase price of $170 million, subject to a post-closing working capital adjustment (the “Acquisition”). The closing of the Acquisition, which is expected to occur in the second quarter of 2012, remains subject to regulatory approval and satisfaction of customary closing conditions.

Pursuant to the Purchase Agreement, the Company will acquire all of the assets of Thomson Reuters that are exclusively related to the PORTIA Business including intellectual property, contracts, trade accounts and notes receivable, prepaid charges and expenses, certain tangible assets, goodwill and other intangible assets. The Company will also assume certain specified liabilities of Thomson Reuters related to the PORTIA Business.

Bank of America, N.A. has committed to provide the Company with a $175 million senior secured term loan, the aggregate proceeds of which will be sufficient for the Company to pay the aggregate purchase consideration and all related fees and expenses in connection with the Acquisition. The commitment is subject to customary conditions, including but not limited to the consummation of the Acquisition and the negotiation of definitive financing documentation. Consummation of the Acquisition is not subject to a financing condition.

The foregoing description of the terms of the Purchase Agreement is qualified in its entirety by reference to the Purchase Agreement, a copy of which is filed as Exhibit 1.1 hereto, and is incorporated herein by reference in its entirety.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

EXHIBIT INDEX