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EXHIBIT 99.1

Repros Therapeutics Inc.(R) Reports First Quarter 2011 Financial Results

THE WOODLANDS, Texas, May 16, 2011 (GLOBE NEWSWIRE) -- Repros Therapeutics Inc.® (Nasdaq:RPRX) today announced financial results for the first quarter ended March 31, 2011.

Financial Results

Net loss for the three-month period ended March 31, 2011, was ($2.1) million or ($0.20) per share as compared to a net loss of ($1.1) million or ($0.17) per share for the same period in 2010. The increase in loss for the three month period ended March 31, 2011 as compared to the same period in 2010 was primarily due to increased expenses in clinical development for Androxal® and Proellex®.         

Research and development ("R&D") expenses increased 223% or approximately $1.0 million to $1.5 million for the three month period ended March 31, 2011 as compared to $458,000 for the same period in the prior year. Our primary R&D expenses for the three month periods ended March 31, 2011 and 2010 are shown in the following table (in thousands): 



Research and Development
Three Months
Ended
March 31, 2011
Three Months
Ended
March 31, 2010


Variance


Change (%)
Operating and occupancy $193 $177 $16 9%
Payroll and benefits 191 120 71 59%
Androxal® clinical development 871 14 857 6,121%
Proellex® clinical development 225 147 78 53%
Total $1,480 $458 $1,022 223%

The increase in R&D expenses is primarily due to the increased clinical development expenses related to Androxal® as a result of the initiation of the Phase 2 study as a potential treatment for Type 2 diabetes in hypogonadal men and the Phase 2B study in men with secondary hypogonadism. R&D expenses were further increased due to the ongoing dose escalating study being conducted on Proellex® initiated in the third quarter of 2010. Additionally, payroll and benefits expenses increased due to increased headcount and the discontinuation of the salary reduction program put in place in August 2009 for all salaried R&D employees.

General and administrative expenses, ("G&A"), decreased 5% or approximately $34,000 to $635,000 for the three month period ended March 31, 2011 as compared to $669,000 for the same period in the prior year. Our primary G&A expenses for the three month period ended March 31, 2011 and 2010 are shown in the following table (in thousands): 

 
 
General and Administrative
Three Months
Ended
March 31, 2011
Three Months
Ended
March 31, 2010
 
 
Variance
 
 
Change (%)
Payroll and benefits $196 $153 $43 28%
Operating and occupancy 439 516 (77) (15)%
Total $635 $669 ($34) (5)%

G&A payroll and benefits expenses include a charge for non-cash stock option expense of $78,000 for the three month period ended March 31, 2011 as compared to $74,000 for the same period in the prior year. Additionally, salaries for the three month period ended March 31, 2011 were $104,000 as compared to $63,000 for the same period in the prior year. The increase in salaries is primarily due to the discontinuation of the salary reduction program put in place in August 2009 for all salaried employees other than Mr. Podolski, the Company's President and CEO, and Mr. Podolski's salary was revised to a 25% reduction.

G&A operating and occupancy expenses, which include expenses to operate as a public company, decreased 15% or approximately $77,000 to $439,000 for the three month period ended March 31, 2011 as compared to $516,000 for the same period in the prior year. The decrease is primarily due to a decrease in professional services.

As of March 31, 2011 we had 11,976,209 shares of common stock outstanding.

About Repros Therapeutics Inc.

Repros Therapeutics Inc. focuses on the development of new drugs to treat hormonal and reproductive system disorders.

The Repros Therapeutics Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=7738

Any statements made by the Company that are not historical facts contained in this release are forward-looking statements that involve risks and uncertainties, including the ability to raise additional needed capital on a timely basis in order for it to continue its operations, have success in the clinical development of its technologies and such other risks which are identified in the Company's most recent Annual Report on Form 10-K and in any subsequent quarterly reports on Form 10-Q. These documents are available on request from Repros Therapeutics or at www.sec.gov. Repros disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

For more information, please visit the Company's website at http://www.reprosrx.com.

REPROS THERAPEUTICS INC. AND SUBSIDIARY
(A Development Stage Company)
     
CONSOLIDATED STATEMENTS OF OPERATIONS
(unaudited and in thousands except per share amounts)
     
  Three Months Ended
  March 31,
  2011 2010
     
     
Revenues and other income  $ --   $ -- 
     
Expenses    
Research and development  1,480  458
General and administrative  635  669
Total expenses  2,115  1,127
     
Net loss  $ (2,115)  $ (1,127)
     
Net loss per share - basic and diluted  $ (0.20)  $ (0.17)
     
Weighted average shares used in loss per share calculation:    
Basic  10,790  6,457
Diluted  10,790  6,457
     
     
CONSOLIDATED BALANCE SHEETS
(unaudited and in thousands)
     
  March 31,
2011
December 31,
2010
     
     
Cash and cash equivalents  $ 12,630  $ 2,957
Prepaid expenses and other currents assets  305  328
Fixed assets (net)  5  7
Patents (net)  1,197  1,173
Total assets  $ 14,137  $ 4,465
     
Accounts payable and accrued expenses   $ 1,451  $ 1,298
Stockholders' equity  12,686  3,167
Total liabilities and stockholders' equity  $ 14,137  $ 4,465
CONTACT: Joseph S. Podolski
         Chief Executive Officer
         (281) 719-3447