Attached files
file | filename |
---|---|
10-Q - FORM 10-Q - ONYX PHARMACEUTICALS INC | f58570e10vq.htm |
EX-31.1 - EX-31.1 - ONYX PHARMACEUTICALS INC | f58570exv31w1.htm |
EX-32.1 - EX-32.1 - ONYX PHARMACEUTICALS INC | f58570exv32w1.htm |
EX-31.2 - EX-31.2 - ONYX PHARMACEUTICALS INC | f58570exv31w2.htm |
EX-10.1.I - EX-10.1(I) - ONYX PHARMACEUTICALS INC | f58570exv10w1wi.htm |
EX-10.13.V - EX-10.13(V) - ONYX PHARMACEUTICALS INC | f58570exv10w13wv.htm |
EXCEL - IDEA: XBRL DOCUMENT - ONYX PHARMACEUTICALS INC | Financial_Report.xls |
Exhibit
10.22(ii)
10513 W. 84th Terrace
Lenexa, KS 66214
P: 913.685.8850
F: 913.685.8856
www.cydexpharma.com
Lenexa, KS 66214
P: 913.685.8850
F: 913.685.8856
www.cydexpharma.com
April 19, 2011
Via Federal Express
Onyx Pharmaceuticals
2100 Powell Street
Emeryville, California 94608
Attention: VP, Development
2100 Powell Street
Emeryville, California 94608
Attention: VP, Development
Re: | Exhibit A to the License and Supply Agreement dated as of October 12, 2005, as amended (Agreement) between CyDex Pharmaceuticals, Inc. (formerly known as CyDex, Inc., CyDex) Onyx Pharmaceuticals (formerly known as Proteolix, Inc. (Company) |
Dear Sir or Madam:
Pursuant to Section 1.20 of the Agreement, CyDex has the right and obligation to update
Exhibit A to the Agreement which lists the Licensed Patents which cover Captisol®. This letter is
provided by CyDex to Company as an official notice pursuant to Section 14.7 of the Agreement to so
update such Exhibit A.
Accordingly, listed in Schedule A, attached hereto, is the complete list of all patents and
patent applications, which hereby replaces the existing definition of Licensed Patents.
Please contact the undersigned if you have any questions.
With best regards,
CYDEX PHARMACEUTICALS, INC.
Allen K. Roberson, General Manager
Enclosure
1
Schedule A
PATENT FAMILY 1: Derivatives of Cyclodextrins Exhibiting Enhanced Aqueous Solubility and the Use Thereof.
Issued Patents
Filing Date | Expiration Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Patent No. | (mm/dd/yyyy) | ||||
United States | 01/23/1990 | 07/469,087 | 5,134,127 | 01/23/2010 | ||||
Australia | 01/22/1991 | 72364/91 | 646020 | 01/22/2011 | ||||
Austria | 01/22/1991 | 91903891.9 | E 170742 | 01/22/2011 | ||||
Belgium | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 | ||||
Canada | 01/22/1991 | 2,074,186 | 2,074,186 | 01/22/2011 | ||||
Europe | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 | ||||
France | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 | ||||
Germany | 01/22/1991 | 6030165.4-08 | 69130165 | 01/22/2011 | ||||
Greece | 01/22/1991 | 980402865 | 3028691 | 01/22/2011 | ||||
Italy | 01/22/1991 | 70988BE/98 | 512050 | 01/22/2011 | ||||
Japan | 01/22/1991 | 504051/93 | 2722277 | 01/22/2011 | ||||
Luxembourg | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 | ||||
Netherlands | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 | ||||
Russia | 01/22/1991 | 5052811.04 | 2099354 | 01/22/2011 | ||||
South Korea | 01/22/1991 | 92-701734 | 166088 | 01/22/2011 | ||||
Sweden | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 | ||||
Switzerland | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 | ||||
United Kingdom | 01/22/1991 | 91903891.9 | 512050 | 01/22/2011 |
PATENT FAMILY 2: Derivatives of Cyclodextrins Exhibiting Enhanced Aqueous Solubility and the Use Thereof.
Issued Patents
Filing Date | Expiration Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Patent No. | (mm/dd/yyyy) | ||||
United States | 07/27/1992 | 07/918,702 | 5,376,645 | 01/23/2010 | ||||
Armenia | 07/26/1993 | 96237 | 822 | 07/26/2013 | ||||
Australia | 07/26/1993 | 47799/93 | 672814 | 07/26/2013 | ||||
Austria | 07/26/1993 | 93918302 | E 217325 | 07/26/2013 |
2
Filing Date | Expiration Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Patent No. | (mm/dd/yyyy) | ||||
Belgium | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Canada | 07/26/1993 | 2,119,154 | 2,119,154 | 07/26/2013 | ||||
Denmark | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Europe | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
France | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Georgia | 07/26/1993 | 1857 | 1649 | 07/26/2013 | ||||
Germany | 07/26/1993 | 6031900 | 69331900 | 07/26/2013 | ||||
Greece | 07/26/1993 | 930620828 | 3040489 | 07/26/2013 | ||||
Ireland | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Italy | 07/26/1993 | 70422BE/2002 | 620828 | 07/26/2013 | ||||
Japan | 07/26/1993 | 6-504678/94 | 3393253 | 07/26/2013 | ||||
Kyrgyzstan | 07/26/1993 | 960481.1 | 333 | 07/26/2013 | ||||
Luxembourg | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Moldova | 07/26/1993 | 960306 | 1813 | 07/26/2013 | ||||
Monaco | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Netherlands | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Portugal | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Russia | 07/26/1993 | 94028890 | 2113442 | 07/26/2013 | ||||
South Korea | 07/26/1993 | 94-700951 | 279111 | 07/26/2013 | ||||
Spain | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Sweden | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Switzerland | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Tajikistan | 07/26/1993 | 96000377 | TJ 275 | 07/26/2013 | ||||
Turkmenistan | 07/26/1993 | 393 | 430 | 07/26/2013 | ||||
United Kingdom | 07/26/1993 | 93918302.6 | 620828 | 07/26/2013 | ||||
Uzbekistan | 07/26/1993 | IHAP9400808 | 5799 | 07/26/2013 |
PATENT FAMILY 15: Sulfoalkyl Ether Cyclodextrin Compositions and Methods of Preparation Thereof.
Issued Patents
Filing Date | Expiration Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Patent No. | (mm/dd/yyyy) | ||||
United States | 01/31/2009 | 12/363,719 | 7,629,331 | 10/26/2025 | ||||
Europe* | 10/26/2005 | 05856927.8 | 1945228 | 10/26/2025 |
3
Pending Applications
Estimated Expiration | ||||||||
Filing Date | Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Publication No. | (mm/dd/yyyy) | ||||
United States | 10/26/2005 | 12/108,228 | 2009/0011037 | 10/26/2025 | ||||
Australia | 10/26/2005 | 2005337613 | 2005337613 | 10/26/2025 | ||||
Brazil | 10/26/2005 | PI0520654-5 | Brazilian Industrial Property Journal No. 2002 | 10/26/2025 | ||||
Canada | 10/26/2005 | 2,632,211 | 2,632,211 | 10/26/2025 | ||||
China | 10/26/2005 | 200580052421.8 | 101365459A | 10/26/2025 | ||||
India | 10/26/2005 | 3462/DELNP/2008 | Not yet published | 10/26/2025 | ||||
Israel | 10/26/2005 | 191081 | Not yet published | 10/26/2025 | ||||
Japan | 10/26/2005 | 2008-537669 | 2009-513773 | 10/26/2025 | ||||
Mexico | 10/26/2005 | MX/a/2008/005397 | Not yet published | 10/26/2025 | ||||
South Korea | 10/26/2005 | 10-2008-7012541 | 10-20080063526 | 10/26/2025 | ||||
Russia | 10/26/2005 | 2008120659 | 2008120659 | 10/26/2025 |
* | The grant date of EP 1945228 will be 04/06/2011. |
PATENT FAMILY 20: Sulfoalkyl Ether Cyclodextrin Compositions
Issued Patents
Filing Date | Expiration Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Patent No. | (mm/dd/yyyy) | ||||
United States | 03/13/2009 | 12/404,174 | 7,635,773 | 03/13/2029 |
Pending Applications
Estimated Expiration | ||||||||
Filing Date | Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Publication No. | (mm/dd/yyyy) | ||||
United States | 11/05/2009 | 12/613,103 | 2010/0093663 | 03/13/2029 | ||||
Australia | 04/28/2009 | 2009241858 | Not yet published | 04/28/2029 | ||||
Brazil | 04/28/2009 | PI0905080-9 | Not yet published | 04/28/2029 | ||||
Canada | 04/28/2009 | 2,702,603 | Not yet published | 04/28/2029 | ||||
China | 04/28/2009 | 200980107665.X | 101959508 | 04/28/2029 |
4
Estimated Expiration | ||||||||
Filing Date | Date | |||||||
Country | (mm/dd/yyyy) | Application No. | Publication No. | (mm/dd/yyyy) | ||||
Eurasia | 04/28/2009 | 201000828 | Not yet published | 04/28/2029 | ||||
Europe | 04/28/2009 | 09739150.2 | 2268269 | 04/28/2029 | ||||
India | 04/28/2009 | To be determined | Not yet published | 04/28/2029 | ||||
Israel | 04/28/2009 | 208956 | Not yet published | 04/28/2029 | ||||
Japan | 04/28/2009 | 2010-525119 | 2010-539193 | 04/28/2029 | ||||
Mexico | 04/28/2009 | MX/a/2010/004900 | MX/a/2010/004900 | 04/28/2029 | ||||
South Korea | 04/28/2009 | 10-2010-7026534 | Not yet published | 04/28/2029 | ||||
New Zealand | 04/28/2009 | 589290 | Not yet published | 04/28/2029 |
5