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10-K - 10-K - HUMAN GENOME SCIENCES INCw81670e10vk.htm
EX-10.2 - EX-10.2 - HUMAN GENOME SCIENCES INCw81670exv10w2.htm
EX-32.2 - EX-32.2 - HUMAN GENOME SCIENCES INCw81670exv32w2.htm
EX-23.1 - EX-23.1 - HUMAN GENOME SCIENCES INCw81670exv23w1.htm
EX-31.1 - EX-31.1 - HUMAN GENOME SCIENCES INCw81670exv31w1.htm
EX-32.1 - EX-32.1 - HUMAN GENOME SCIENCES INCw81670exv32w1.htm
EX-10.3 - EX-10.3 - HUMAN GENOME SCIENCES INCw81670exv10w3.htm
EX-31.2 - EX-31.2 - HUMAN GENOME SCIENCES INCw81670exv31w2.htm
EX-21.1 - EX-21.1 - HUMAN GENOME SCIENCES INCw81670exv21w1.htm
EXHIBIT 12.1
                                         
    Ratio of Earnings to Fixed Charges  
    (dollars in thousands, except ratio data)  
    Year ended December 31,  
    2010     2009     2008     2007     2006  
Earnings (Loss):
                                       
Earnings (loss) before provision for income taxes
  $ (233,231 )   $ 4,385     $ (268,891 )   $ (284,371 )   $ (264,087 )
Fixed Charges
    78,108       77,780       82,930       80,927       59,505  
 
                             
 
                                       
Total Earnings (Loss)
  $ (155,123 )   $ 82,165     $ (185,961 )   $ (203,444 )   $ (204,582 )
 
                             
 
                                       
Fixed Charges:
                                       
Interest expense on indebtedness (including amortization of debt expense and discount)
  $ 59,500     $ 58,424     $ 62,912     $ 60,716     $ 39,606  
Interest expense on portion of rent expense representative of interest
    18,608       19,356       20,018       20,211       19,899  
 
                             
 
                                       
Total Fixed Charges
  $ 78,108     $ 77,780     $ 82,930     $ 80,927     $ 59,505  
 
                             
 
                                       
Ratio of Earnings to Fixed Charges
          1.06                    
 
                                       
Coverage deficiency (1)(2)(3)
  $ (233,231 )   $     $ (268,891 )   $ (284,371 )   $ (264,087 )
 
                             
 
(1)   The Company’s Ratio of Earnings to Fixed Charges for 2009 includes a gain on extinguishment debt of $38,873, a gain on sale of an equity investment of $5,259 and reflects revenues received in connection with the delivery of raxibacumab to the Strategic National Stockpile. These amounts should not be considered indicative of the Company’s future performance.
 
(2)   The Company’s Coverage deficiency for 2008 includes a gain on the sale of an equity investment of $32,518 partially offset by a charge for impaired investment of $6,284.
 
(3)   The Company’s Coverage deficiency for 2006 includes charges for facility-related exit charges of $29,510 partially offset by a gain on the sale of an equity investment of $14,759.