Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

Date of Report (Date of Earliest Event Reported):   October 29, 2009

Altus Pharmaceuticals Inc.
(Exact name of registrant as specified in its charter)

Delaware 0-51711 04-3573277
(State or other jurisdiction
(I.R.S. Employer
of incorporation) File Number) Identification No.)
PO Box 403, Burlington, Massachusetts   01803
(Address of principal executive offices)
(Zip Code)
Registrant’s telephone number, including area code:   781-373-6000

Not Applicable
Former name or former address, if changed since last report


Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:

[  ]  Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
[  ]  Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
[  ]  Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
[  ]  Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On October 29, 2009, the Board of Directors determined to discontinue the employment of Georges Gemayel, Ph.D. and Thomas J. Phair, Jr., with Dr. Gemayal to continue as a director and Dr. Gemayel and Mr. Phair both to continue as statutory officers without compensation pending the wind down of operations.


Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

    Altus Pharmaceuticals Inc.
November 4, 2009   By:   Thomas J. Phair, Jr.
        Name: Thomas J. Phair, Jr.
        Title: Vice President, Finance and Treasurer