Exhibit 99.1

MARKETAXESS REPORTS THIRD QUARTER 2009 DILUTED EPS OF $0.12,
RECORD REVENUES OF $30.0 MILLION

Company Announces First Regular Quarterly Dividend of $0.07 per Share

Third Quarter Financial Highlights^*

•		Revenues of $30.0 million, up 32.3%
•		Variable transaction fees of $14.6 million, up 136.3%
•		Total expenses of $21.5 million, up 4.3%
•		Record pre-tax income of $8.5 million, up 307.2%
•		Pre-tax margin of 28.5%, up from 9.3%
•		Net income of $4.6 million, up 205.5%

NEW YORK, October 28, 2009 — MarketAxess Holdings Inc. (Nasdaq: MKTX), the operator of a leading electronic trading platform for U.S. and European high-grade corporate bonds, emerging markets bonds and other types of fixed-income securities, today announced results for the third quarter ended September 30, 2009.

“Our efforts to increase investor order flow and broaden the sources of liquidity paid off with record revenues and record pre-tax income during the quarter,” said Richard M. McVey, chairman and chief executive officer of MarketAxess. “The improvement in credit market conditions is driving increased demand for electronic trading. Investor orders are up 78% year over year, estimated overall market share is trending higher once again and fee capture continues to improve.”

Third Quarter Results

Total revenues for the third quarter of 2009 increased 32.3% to $30.0 million, compared to $22.7 million for the third quarter of 2008. Pre-tax income was $8.5 million, compared to $2.1 million for the third quarter of 2008, an increase of 307.2%. Pre-tax margin was 28.5%, compared to 9.3% for the third quarter of 2008. Net income totaled $4.6 million, or $0.12 per share on a diluted basis, compared to $1.5 million, or $0.04 per share on a diluted basis, for the third quarter of 2008.

Commission revenue for the third quarter of 2009 totaled $25.3 million on total trading volume of $80.4 billion, compared to $17.2 million in commission revenue on total trading volume of $49.0 billion for the third quarter of 2008. U.S. high-grade trading volume as a percentage of FINRA’s high-grade TRACE trading volume increased to an estimated 6.5%, compared to an estimated 6.4% for the third quarter of 2008 and 4.7% for the second quarter of 2009.

Technology products and services revenue, which includes revenue for technology licenses, support and professional services, totaled $2.6 million for both the third quarter of 2009 and the third quarter of 2008. Other revenue, which consists of information and user access fees, investment income and other revenue, decreased 24.8% to $2.1 million, compared to $2.8 million for the third quarter of 2008, due to a decline in investment income as a result of lower interest rates.

Total expenses for the third quarter of 2009 increased 4.3% to $21.5 million, compared to $20.6 million for the third quarter of 2008. The increase was primarily due to higher employee compensation and benefits expense of $2.0 million, offset by lower depreciation and amortization expenses of $0.8 million. The Company now expects total expenses for 2009 to be in the range of $83.0 million to $84.5 million. The Company now expects its full year 2009 capital spending to be in the range of $7.5 million to $8.5 million.

The effective tax rate for the third quarter of 2009 was 45.7%, compared to 27.6% for the third quarter of 2008 and 38.5% for full year 2008. The 2008 effective tax rate reflected the effect of a higher portion of earnings generated in lower tax jurisdictions and the level of foreign and domestic taxation on such overseas earnings. The 2009 third quarter effective tax rate reflects the impact on our deferred tax asset of newly enacted apportionment rules in New York City. The new rules will reduce the Company’s overall tax rate in the future. The Company anticipates that the effective tax rate for the fourth quarter of 2009 will be between 42% and 44%.

Employee headcount as of September 30, 2009 was 210, compared to 185 as of September 30, 2008.

Dividend

The Company’s board of directors has approved a regular quarterly dividend to be paid to the holders of the outstanding shares of capital stock. A cash dividend of $0.07 per share of common stock outstanding or issuable upon conversion of outstanding shares of non-voting common stock and Series B preferred stock will be paid on November 25, 2009 to stockholders of record as of the close of business on November 11, 2009.

“The Board has elected to pay our first regular cash dividend because we have consistently generated strong cash flow, well in excess of our anticipated capital spending needs,” said James N.B. Rucker, chief financial officer of MarketAxess. “Our priority is to continue investing in the business to support long term growth while maintaining our strong financial profile.”

Balance Sheet Data

As of September 30, 2009, total assets were $267.5 million and included $162.3 million in cash, cash equivalents and securities, and a deferred tax asset of $29.0 million. Total stockholders’ equity, including the Series B preferred stock, as of September 30, 2009 was $242.1 million.

Webcast and Conference Call Information

Richard M. McVey, MarketAxess’ chairman and chief executive officer, T. Kelley Millet, president, and James N.B. Rucker, chief financial officer, will host a conference call to discuss the Company’s financial results and outlook this morning at 8:30 a.m. Eastern time. To access the conference call, please dial 866-543-6405 (U.S.) or 617-213-8897 (international). The passcode for all callers is 98764520. The Company will also host a live audio webcast of the conference call on the Investor Relations section of the Company’s website at www.marketaxess.com. An archive of the call will be available by dialing 888-286-8010 (U.S.) or 617-801-6888 (international) for one week after the announcement. The passcode for replay callers is 24589980. The web cast will also be archived at www.marketaxess.com for 90 days following the announcement.

About MarketAxess

MarketAxess operates one of the leading platforms for the electronic trading of corporate bonds and certain other types of fixed-income securities, serving as an electronic platform through which our approximately 700 active institutional investor clients can access the liquidity provided by our 67 broker-dealer clients. Our multi-dealer trading platform allows our institutional investor clients to simultaneously request competitive, executable bids or offers from multiple broker-dealers, and to execute trades with the broker-dealer of their choice. We offer our clients the ability to trade U.S. high-grade corporate bonds, European high-grade corporate bonds, credit default swaps, agencies, high-yield and emerging markets bonds. Our DealerAxess^® trading service allows dealers to trade fixed-income securities with each other on our platform. We execute certain bond transactions between and among institutional investor and broker-dealer clients on a riskless principal basis by serving as counterparty to both the buyer and the seller in matching back-to-back trades, which are then settled through a third-party clearing organization. We also provide data and analytical tools that help our clients make trading decisions, we provide connectivity solutions that facilitate the trading process by electronically communicating order information between trading counterparties and we provide our clients with ancillary technology services.

Cautionary Note Regarding Forward-Looking Statements

This press release may contain forward-looking statements, including statements about the outlook and prospects for Company and industry growth, as well as statements about the Company’s future financial and operating performance. These and other statements that relate to future results and events are based on MarketAxess’ current expectations. Actual results in future periods may differ materially from the those currently expected or desired because of a number of risks and uncertainties, including: our dependence on our broker-dealer clients; the level and intensity of competition in the fixed-income electronic trading industry and the pricing pressures that may result; the variability of our growth rate; our limited operating history; the level of trading volume transacted on the MarketAxess platform; the absolute level and direction of interest rates and the corresponding volatility in the corporate fixed-income market; our ability to develop new products and offerings and the market’s acceptance of those products; our ability to enter into strategic alliances and to acquire other businesses and successfully integrate them with our business; our future capital needs and our ability to obtain capital when needed; our exposure to risks resulting from non-performance by counterparties to transactions executed between our clients in which we act as an intermediary in matching back-to-back trades; and other factors. The Company’s actual results and financial condition may differ, perhaps materially, from the anticipated results and financial condition in any such forward-looking statements. The Company undertakes no obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise. More information about these and other factors affecting MarketAxess’ business and prospects is contained in MarketAxess’ periodic filings with the Securities and Exchange Commission and can be accessed at www.marketaxess.com.

# # #

Media and Investor Relations Contacts:
James Rucker		William McBride
MarketAxess Holdings Inc.		Gavin Anderson & Co.
+1-212-813-6383		+1-212-515-1970

MarketAxess Holdings Inc.
Consolidated Statements of Operations

		Three Months Ended								Nine Months Ended
		September 30,								September 30,
		2009				2008				2009				2008
		($ in thousands, except per share data)
		(unaudited)
Revenues
Commissions
U.S. high-grade		$	16,306			$	10,777			$	43,629			$	35,733
Eurobond			5,497				4,427				14,351				14,136
Other			3,486				2,015				9,585				6,783
Total commissions			25,289				17,219				67,565				56,652
Technology products and services			2,601				2,646				6,720				6,089
Information and user access fees			1,519				1,562				4,678				4,485
Investment income			314				963				880				2,715
Other			286				291				637				1,316
Total revenues			30,009				22,681				80,480				71,257
Expenses
Employee compensation and benefits			13,127				11,173				36,486				33,767
Depreciation and amortization			1,654				2,494				5,124				6,090
Technology and communications			2,029				2,007				6,391				6,160
Professional and consulting fees			1,645				1,822				5,137				6,496
Occupancy			706				660				2,075				2,166
Marketing and advertising			651				708				2,004				2,077
General and administrative			1,654				1,719				4,253				4,679
Total expenses			21,466				20,583				61,470				61,435
Income before taxes			8,543				2,098				19,010				9,822
Provision for income taxes			3,903				579				8,344				3,859
Net income		$	4,640			$	1,519			$	10,666			$	5,963
Per Share Data:
Earnings per share:
Basic		$	0.13			$	0.04			$	0.29			$	0.17
Diluted		$	0.12			$	0.04			$	0.28			$	0.17
Weighted-average common shares:
Basic			33,287				32,952				33,242				32,766
Diluted			38,197				37,438				37,856				35,188

MarketAxess Holdings Inc.
Consolidated Condensed Balance Sheet Data

		September 30, 2009				December 31, 2008
		($ in thousands)
		(unaudited)				(audited)
Assets
Cash and cash equivalents		$	106,133			$	107,323
Securities available-for-sale			56,194				35,227
Deferred tax assets, net			28,988				35,666
All other assets			76,185				68,212
Total assets		$	267,500			$	246,428
Liabilities and Stockholders’ Equity
Total liabilities		$	25,374			$	21,620
Series B Preferred Stock			30,315				30,315
Total stockholders’ equity			211,811				194,493
Total liabilities and stockholders’ equity		$	267,500			$	246,428

MarketAxess Holdings Inc.
Volume Statistics

		Total Trading Volume
		Three Months Ended								Nine Months Ended
		September 30,								September 30,
		2009				2008				2009				2008
		($ in millions)
		(unaudited)
U.S. high-grade — multi dealer 1
fixed-rate		$	45,432			$	24,419			$	117,766			$	95,418
floating-rate			1,587				1,766				4,002				7,312
U.S. high-grade — single dealer2			—				1,363				—				6,269
Eurobond			16,580				8,576				38,841				28,447
Other1			16,795				12,892				46,677				45,846
Total		$	80,394			$	49,016			$	207,286			$	183,292

		Average Daily Volume
		Three Months Ended								Nine Months Ended
		September 30,								September 30,
		2009				2008				2009				2008
		($ in millions)
		(unaudited)
U.S. high-grade1		$	735			$	430			$	648			$	577
Eurobond			255				132				206				150
Other1			262				201				248				243
Total		$	1,252			$	763			$	1,102			$	970
Number of U.S. Trading Days 3			64				64				188				189
Number of U.K. Trading Days 4			65				65				189				190