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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549

FORM 10-Q

(MARK ONE)

[X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934

For the quarterly period ended March 31, 2005

or

[ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES
EXCHANGE ACT OF 1934

For the transition period from ___________ to ____________

Commission file number 0-23621

MKS INSTRUMENTS, INC.

(Exact name of registrant as specified in its charter)

Massachusetts 04-2277512
- --------------------------------------------------------------------------------
(State or other jurisdiction (I.R.S. Employer
of incorporation or organization) Identification No.)

90 Industrial Way, Wilmington, Massachusetts 01887
- --------------------------------------------------------------------------------
(Address of principal executive offices) (Zip Code)

Registrant's telephone number, including area code (978) 284-4000

Indicate by check mark whether the registrant: (1) has filed all reports
required to be filed by Section 13 or 15(d) of the Securities Exchange Act of
1934 during the preceding 12 months (or for such shorter period that the
registrant was required to file such reports), and (2) has been subject to such
filing requirements for the past 90 days. Yes [X] No [ ].

Indicate by check mark whether the registrant is an accelerated filer (as
defined in Rule 12b-2 of the Exchange Act). Yes [X] No [ ].

Number of shares outstanding of the issuer's common stock as of April 28,
2005: 53,930,001



MKS INSTRUMENTS, INC.
FORM 10-Q
INDEX



PART I. FINANCIAL INFORMATION 3

ITEM 1. FINANCIAL STATEMENTS. 3

Consolidated Balance Sheets -
March 31, 2005 and December 31, 2004 3

Consolidated Statements of Operations -
Three months ended March 31, 2005 and 2004 4

Consolidated Statements of Cash Flows -
Three months ended March 31, 2005 and 2004 5

Notes to Consolidated Financial Statements 6

ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL
CONDITION AND RESULTS OF OPERATIONS. 13

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK. 25

ITEM 4. CONTROLS AND PROCEDURES. 25

PART II. OTHER INFORMATION 26

ITEM 1. LEGAL PROCEEDINGS. 26

ITEM 6. EXHIBITS. 27


2



PART I. FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS.

MKS INSTRUMENTS, INC.
CONSOLIDATED BALANCE SHEETS
(in thousands, except share data)



March 31, 2005 December 31, 2004
-------------- -----------------
(Unaudited)

ASSETS

Current assets:
Cash and cash equivalents............................................ $ 150,233 $ 138,389
Short-term investments............................................... 94,684 97,511
Trade accounts receivable, net....................................... 82,770 82,315
Inventories.......................................................... 97,663 99,633
Deferred income taxes................................................ 11,638 12,129
Other current assets................................................. 10,348 9,908
--------- ---------
Total current assets............................................. 447,336 439,885
Long-term investments................................................ 2,597 4,775
Property, plant and equipment, net................................... 80,197 80,917
Goodwill, net........................................................ 256,114 255,740
Acquired intangible assets, net...................................... 37,806 41,604
Deferred income taxes................................................ 2,237 2,184
Other assets......................................................... 3,145 3,572
--------- ---------
Total assets..................................................... $ 829,432 $ 828,677
========= =========

LIABILITIES AND STOCKHOLDERS' EQUITY

Current liabilities:
Short-term borrowings................................................ $ 19,742 $ 22,440
Current portion of long-term debt.................................... 2,060 2,069
Accounts payable..................................................... 26,283 23,338
Accrued compensation................................................. 10,650 13,767
Income taxes payable................................................. 8,814 9,133
Other accrued expenses............................................... 19,716 21,438
--------- ---------
Total current liabilities........................................ 87,265 92,185
Long-term debt........................................................... 6,690 6,667
Other liabilities........................................................ 3,621 3,191
Commitments and contingencies (Note 9)

Stockholders' equity:
Preferred Stock, $0.01 par value, 2,000,000 shares
authorized; none issued and outstanding.......................... - -
Common Stock, no par value, 200,000,000 shares authorized;
53,924,201 and 53,839,098 issued and outstanding at
March 31, 2005 and December 31, 2004, respectively............... 113 113
Additional paid-in capital........................................... 632,808 631,760
Retained earnings.................................................... 87,535 82,077
Accumulated other comprehensive income............................... 11,400 12,684
--------- ---------
Total stockholders' equity....................................... 731,856 726,634
--------- ---------
Total liabilities and stockholders' equity....................... $ 829,432 $ 828,677
========= =========


The accompanying notes are an integral part of the consolidated financial
statements.

3



MKS INSTRUMENTS, INC.
CONSOLIDATED STATEMENTS OF OPERATIONS
(in thousands, except per share data)
(Unaudited)



Three Months Ended
March 31,
2005 2004
---- ----

Net sales......................................................... $ 127,407 $ 132,985
Cost of sales..................................................... 78,045 78,756
----------- ----------
Gross profit...................................................... 49,362 54,229

Research and development.......................................... 14,549 14,336
Selling, general and administrative............................... 23,849 20,152
Amortization of acquired intangible assets........................ 3,690 3,693
Restructuring charges............................................. 454 437
----------- ----------
Income from operations............................................ 6,820 15,611
Interest expense.................................................. 174 152
Interest income................................................... 1,272 424
----------- ----------
Income before income taxes........................................ 7,918 15,883
Provision for income taxes........................................ 2,460 3,177
----------- ----------
Net income........................................................ $ 5,458 $ 12,706
=========== ==========

Net income per share:
Basic........................................................ $ 0.10 $ 0.24
=========== ==========
Diluted...................................................... $ 0.10 $ 0.23
=========== ==========

Weighted average common shares outstanding:
Basic........................................................ 53,878 53,255
=========== ==========
Diluted...................................................... 54,393 55,085
=========== ==========


The accompanying notes are an integral part of the consolidated financial
statements.

4



MKS INSTRUMENTS, INC.
CONSOLIDATED STATEMENTS OF CASH FLOWS
(in thousands)
(Unaudited)



Three Months Ended
March 31,
2005 2004
---- ----

Cash flows from operating activities:
Net income............................................................................ $ 5,458 $ 12,706
Adjustments to reconcile net income to net cash provided by
operating activities:
Depreciation and amortization.................................................... 6,713 6,913
Other............................................................................ 107 126
Changes in operating assets and liabilities:
Trade accounts receivable.................................................... (1,785) (21,590)
Inventories.................................................................. 699 (12,276)
Other current assets......................................................... (547) (2,520)
Accrued expenses and other current liabilities............................... (2,646) 5,745
Accounts payable............................................................. 1,802 8,991
Income taxes payable......................................................... 84 8,631
-------- --------
Net cash provided by operating activities............................................. 9,885 6,726
-------- --------

Cash flows from investing activities:
Purchases of short-term and long-term available for sale investments.............. (45,434) (44,030)
Maturities and sales of short-term and long-term available for sale investments... 51,937 23,240
Purchases of property, plant and equipment........................................ (2,342) (4,248)
Other............................................................................. 366 802
-------- --------
Net cash provided by (used in) investing activities................................... 4,527 (24,236)
-------- --------

Cash flows from financing activities:
Proceeds from short-term borrowings............................................... 21,067 23,452
Payments on short-term borrowings................................................. (22,982) (21,576)
Principal payments on long-term debt.............................................. (390) (486)
Proceeds from issuance of common stock, net of issuance costs..................... - 32,529
Proceeds from exercise of stock options and employee stock purchase plan.......... 746 1,895
-------- --------
Net cash (used in) provided by financing activities................................... (1,559) 35,814
-------- --------

Effect of exchange rate changes on cash and cash equivalents.......................... (1,009) (1,032)
-------- --------
Increase in cash and cash equivalents................................................. 11,844 17,272
Cash and cash equivalents at beginning of period...................................... 138,389 74,660
-------- --------
Cash and cash equivalents at end of period............................................ $150,233 $ 91,932
======== ========


The accompanying notes are an integral part of the consolidated financial
statements.

5



MKS INSTRUMENTS, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS
(Tables in thousands, except per share data)

1) Basis of Presentation

The terms "MKS" and the "Company" refer to MKS Instruments, Inc. and its
subsidiaries. The interim financial data as of March 31, 2005 and for the
three months ended March 31, 2005 and 2004 is unaudited; however, in the
opinion of MKS, the interim data includes all adjustments, consisting only
of normal recurring adjustments, necessary for a fair statement of the
results for the interim periods. The unaudited consolidated financial
statements presented herein have been prepared in accordance with the
instructions to Form 10-Q and do not include all of the information and
note disclosures required by generally accepted accounting principles. The
consolidated financial statements should be read in conjunction with the
December 31, 2004 audited consolidated financial statements and notes
thereto included in the MKS Annual Report on Form 10-K filed with the
Securities and Exchange Commission on March 16, 2005.

The preparation of these consolidated financial statements requires
management to make estimates and assumptions that affect the reported
amounts of assets and liabilities and the disclosure of contingent
liabilities at the date of the consolidated financial statements and the
reported amounts of revenues and expenses during the reporting period. On
an on-going basis, management evaluates its estimates and judgments,
including those related to revenue recognition, accounts receivable,
inventory, intangible assets, goodwill, other long-lived assets, income
taxes, deferred tax valuation allowance and investments. Management bases
its estimates and judgments on historical experience and on various other
factors that are believed to be reasonable under the circumstances, the
results of which form the basis for making judgments about the carrying
values of assets and liabilities that are not readily apparent from other
sources. Actual results may differ from these estimates under different
assumptions or conditions.

2) Stock-Based Compensation

The Company has several stock-based employee compensation plans. The
Company accounts for stock-based awards to employees using the intrinsic
value method as prescribed by Accounting Principles Board Opinion No. 25,
"Accounting for Stock Issued to Employees," and related interpretations.
Accordingly, no compensation expense is recorded for options issued to
employees in fixed amounts with fixed exercise prices at least equal to
the fair market value of the Company's common stock at the date of grant.
The Company has adopted the provisions of Statement of Financial
Accounting Standards ("SFAS") No. 123, "Accounting for Stock-Based
Compensation," as amended by SFAS No. 148, "Accounting for Stock-Based
Compensation-Transition and Disclosure," ("SFAS 123") through disclosure
only.

The following table illustrates the effect on net income and net income
per share if the Company had applied the fair value recognition provisions
of SFAS No. 123 to stock-based employee awards.



Three Months Ended
March 31,
2005 2004
---- ----

Net income as reported ........................................................... $ 5,458 $ 12,706
Deduct: Total stock-based employee compensation expense determined under the
fair-value-based method for all awards, net of tax ........................ (18,890) (6,074)
----------- ----------
Pro forma net income (loss) ...................................................... $ (13,432) $ 6,632
=========== ==========
Basic net income (loss) per share:
As reported ................................................................. $ 0.10 $ 0.24
=========== ==========
Pro forma ................................................................... $ (0.25) $ 0.12
=========== ==========
Diluted net income (loss) per share:
As reported ................................................................. $ 0.10 $ 0.23
=========== ==========
Pro forma ................................................................... $ (0.25) $ 0.12
=========== ==========


6



MKS INSTRUMENTS, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS - (continued)
(Tables in thousands, except per share data)

There was no tax benefit included in the stock-based employee compensation
expense determined under the fair-value-based method for the three months
ended March 31, 2004, as the Company had a full valuation allowance for
its net deferred tax assets at March 31, 2004. For the three months ended
March 31, 2005, stock-based employee compensation expense is net of the
related tax benefit.

In December 2004, the FASB issued Statement of Financial Accounting
Standards No. 123R, "Share-Based Payment" ("SFAS 123R"). SFAS 123R
replaces SFAS 123 and supersedes APB 25. SFAS 123R focuses primarily on
the accounting for transactions in which an entity obtains employee
services in share-based payment transactions. SFAS 123R requires companies
to recognize in the statement of operations the cost of employee services
received in exchange for awards of equity instruments based on the
grant-date fair value of those awards. SFAS 123R was originally expected
to be effective for the Company beginning in its third quarter of fiscal
2005. In April 2005, the effective date was amended by the Securities and
Exchange Commission. As a result, SFAS 123R is now effective for the
Company as of the first annual period that begins after June 15, 2005.
Accordingly, the Company will adopt SFAS 123R in its first quarter of
fiscal 2006. The Company expects to use the modified-prospective
transition method and will not restate prior periods for the adoption of
SFAS 123R. Although the Company is currently evaluating the provisions of
SFAS 123R and its implications on its employee benefit plans, it believes
that the adoption of this standard, based on the terms of the options
outstanding at March 31, 2005, will have a material effect on its net
income for the year ending December 31, 2006.

On January 7, 2005, the Company accelerated the vesting of outstanding
stock options granted to employees and officers with an exercise price of
$23.00 or greater. As a result of this action, options to purchase
approximately 1.6 million shares of the Company's common stock became
exercisable on January 7, 2005. No compensation expense was recorded in
the Company's Consolidated Statement of Operations for the three months
ended March 31, 2005 related to this action as these options had no
intrinsic value on January 7, 2005. For purposes of the SFAS No. 123
proforma calculation above, the expense related to the options that were
accelerated was $16,886,000, net of tax, for the three months ended March
31, 2005. The reason that the Company accelerated the vesting of the
identified stock options was to reduce the Company's compensation expense
in periods subsequent to the adoption of SFAS 123R.

3) Goodwill and Intangible Assets

Intangible Assets

Acquired amortizable intangible assets consisted of the following as of
March 31, 2005:



Gross Carrying Accumulated Net Carrying
Amount Amortization Amount
------ ------------ ------

Completed technology.......................................... $ 72,632 $(43,049) $29,583
Customer relationships........................................ 6,640 (3,811) 2,829
Patents, trademarks, tradenames and other..................... 12,393 (6,999) 5,394
-------- -------- -------
$ 91,665 $(53,859) $37,806
======== ======== =======


Acquired amortizable intangible assets consisted of the following as of
December 31, 2004:



Net
Gross Carrying Accumulated Carrying
Amount Amortization Amount
------ ------------ ------

Completed technology.......................................... $ 72,738 $(39,969) $32,769
Customer relationships........................................ 6,640 (3,581) 3,059
Patents, trademarks, tradenames and other..................... 12,395 (6,619) 5,776
-------- -------- -------
$ 91,773 $(50,169) $41,604
======== ======== =======


7



MKS INSTRUMENTS, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS - (continued)
(Tables in thousands, except per share data)

Aggregate amortization expense related to acquired intangibles for the
three months ended March 31, 2005 and 2004 was $3,690,000 and $3,693,000,
respectively. Estimated amortization expense related to acquired
intangibles for the remainder of 2005 and for each of the four succeeding
fiscal years is as follows:



Year Amount
---- ------

2005 $10,173
2006 11,763
2007 11,129
2008 2,759
2009 1,205


Goodwill

The change in the carrying amount of goodwill during the three months
ended March 31, 2005 was not material.

4) Net Income Per Share

The following table sets forth the computation of basic and diluted net
income per share:



Three Months Ended
March 31,
2005 2004
---- ----

Numerator
Net income .............................................. $ 5,458 $ 12,706
======= ========
Denominator
Shares used in net income per common share - basic ........ 53,878 53,255
Effect of dilutive securities:
Stock options and employee stock purchase plan ....... 515 1,830
------- --------
Shares used in net income per common share - diluted ...... 54,393 55,085
======= ========
Net income per common share
Basic .................................................. $ 0.10 $ 0.24
======= ========
Diluted ................................................ $ 0.10 $ 0.23
======= ========


For purposes of computing diluted net income per common share, 7,164,024
and 2,543,000 outstanding options for the three months ended March 31,
2005 and 2004, respectively, were excluded from the calculation as their
inclusion would be anti-dilutive. There were options to purchase
approximately 9,938,150 and 9,111,000 shares of the Company's common stock
outstanding as of March 31, 2005 and 2004, respectively.

5) Inventories

Inventories consist of the following:



March 31, December 31,
2005 2004
---- ----

Raw material..................................................... $49,537 $46,479
Work in process.................................................. 19,895 18,330
Finished goods................................................... 28,231 34,824
------- -------
$97,663 $99,633
======= =======


8



MKS INSTRUMENTS, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS - (continued)
(Tables in thousands, except per share data)

6) Stockholders' Equity

Comprehensive Income

Components of comprehensive income were as follows:



Three Months Ended
March 31,
2005 2004
---- ----

Net income....................................................................... $ 5,458 $ 12,706
Other comprehensive income (loss):
Changes in value of financial instruments designated as cash flow
hedges (net of taxes of $515 and $0, respectively)........................ 856 510
Foreign currency translation adjustment...................................... (2,078) 54
Unrealized gain (loss) on investments (net of tax
benefit of $38 and $0, respectively)...................................... (62) 26
------- --------
Other comprehensive income (loss)................................................ (1,284) 590
------- --------
Total comprehensive income....................................................... $ 4,174 $ 13,296
======= ========


Common Stock Offering

On January 21, 2004, the Company issued 1,142,857 shares of its common
stock at $26.25 per share through a public offering. Proceeds of the
offering, net of underwriters' discount and offering expenses, were
approximately $28,251,000. On January 23, 2004, the underwriters exercised
their over-allotment option and therefore, the Company issued an
additional 171,429 shares of its common stock, which generated net
proceeds of approximately $4,298,000.

7) Income Taxes

The Company records income taxes using the asset and liability method.
Deferred income tax assets and liabilities are recognized for the future
tax consequences attributable to differences between the consolidated
financial statement carrying amounts of existing assets and liabilities
and their respective income tax bases, and operating loss and tax credit
carryforwards. The Company evaluates the realizability of its net deferred
tax assets and assesses the need for a valuation allowance on a quarterly
basis. The future benefit to be derived from its deferred tax assets is
dependent upon its ability to generate sufficient future taxable income to
realize the assets. The Company records a valuation allowance to reduce
its net deferred tax assets to the amount that may be more likely than not
to be realized. To the extent the Company establishes a valuation
allowance, an expense will be recorded within the provision for income
taxes line on the consolidated statements of operations.

As a result of incurring significant operating losses from 2001 through
2003, the Company established a full valuation allowance for its net
deferred tax assets. During the fourth quarter of 2004, after examining a
number of factors, including historical results and near term earnings
projections, the Company determined that it was more likely than not that
it would realize all of its net deferred tax assets, except for those
related to certain state tax credits. At March 31, 2005, the Company
continues to maintain a valuation allowance for certain state tax credits
for which it is more likely than not that they will not be realized.

The Company's effective tax rate for the quarter ending March 31, 2005 was
31%. The effective tax rate is less than the statutory tax rate primarily
due to the profits of the Company's international subsidiaries being taxed
at rates lower than the U.S. statutory tax rate.

On October 22, 2004, the American Jobs Creation Act of 2004 (the "Act")
was signed into law. The Act contains a provision allowing U.S.
multinational companies a one-time incentive to repatriate foreign
earnings at an effective tax rate of 5.25%. The Company has continued to
examine the effects of the repatriation provision but is awaiting the
issuance of clarifying regulations from the Treasury Department before
completing its evaluation. Through March 31, 2005, the Company has not
provided deferred income taxes on the undistributed earnings of

9



MKS INSTRUMENTS, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS - (continued)
(Tables in thousands, except per share data)

its foreign subsidiaries because such earnings were intended to be
permanently reinvested outside the U.S. Determination of the potential
deferred income tax liability on these undistributed earnings is not
practicable because such liability, if any, is dependent on circumstances
existing if and when remittance occurs. At March 31, 2005, the Company had
$58,213,000 of undistributed earnings in its foreign subsidiaries.

8) Geographic, Product and Significant Customer Information

The Company operates in one segment for the development, manufacturing,
sales and servicing of products that measure, control, power and monitor
critical parameters of advanced manufacturing processes. The Company's
chief decision maker reviews operating results for the entire Company to
make decisions about allocating resources and assessing performance for
the entire Company.

Information about the Company's operations in different geographic regions
is presented in the tables below. Net sales to unaffiliated customers are
based on the location in which the sale originated. Transfers between
geographic areas are at negotiated transfer prices and have been
eliminated from consolidated net sales.



Three Months Ended
March 31,
2005 2004
---- ----

Geographic net sales
United States.............................................................. $ 77,917 $ 84,976
Japan...................................................................... 21,062 21,355
Europe..................................................................... 14,897 11,521
Asia....................................................................... 13,531 15,133
--------- ----------
$ 127,407 $ 132,985
========= ==========




March 31, December 31,
2005 2004
---- ----

Long-lived assets:
United States............................................................. $67,867 $68,719
Japan..................................................................... 6,042 6,202
Europe.................................................................... 5,304 5,544
Asia...................................................................... 4,129 4,024
------- -------
$83,342 $84,489
======= =======


The Company groups its products into three product groups. Net sales for
these product groups are as follows:



Three Months Ended
March 31,
2005 2004
---- ----

Instruments and Control Systems............................................ $ 60,850 $ 61,360
Power and Reactive Gas Products............................................ 52,359 54,805
Vacuum Products............................................................ 14,198 16,820
--------- ---------
$ 127,407 $ 132,985
========= =========


The Company had two customers comprising 15% and 10%, respectively, of net
sales for the three months ended March 31, 2005 and one customer
comprising 20% of net sales for the three months ended March 31, 2004.

10



MKS INSTRUMENTS, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS - (continued)
(Tables in thousands, except per share data)

9) Commitments and Contingencies

On April 3, 2003, Advanced Energy Industries, Inc. ("Advanced Energy")
filed suit against MKS in federal district court in Colorado ("Colorado
Action"), seeking a declaratory judgment that Advanced Energy's Xstream
product does not infringe three patents held by MKS' subsidiary, Applied
Science and Technology, Inc. ("ASTeX"). On May 14, 2003, MKS brought suit
in federal district court in Delaware against Advanced Energy for
infringement of five ASTeX patents (the "Delaware Action"), including the
three patents at issue in the Colorado Action. MKS sought injunctive
relief and damages for Advanced Energy's infringement. On December 24,
2003, the Colorado court granted our motion to transfer Advanced Energy's
Colorado Action to Delaware. In connection with the jury trial, the
parties agreed to present the jury with representative claims from three
of the five ASTeX patents. On July 23, 2004, the jury found that Advanced
Energy infringed all three patents. On March 31 and April 5, 2005, the
Court issued orders concerning a number of pre- and post-trial motions.
Several other post-trial motions remain pending. The Court referred
several of the pending motions to a special master for decision, and the
Court scheduled a hearing for May 26, 2005 to address scheduling issues,
including the trial of any remaining issues in the Delaware Action. MKS
expects that the second phase of trial will address MKS' claims of damages
and willful infringement against Advanced Energy and will also address
certain of Advanced Energy's affirmative defenses that remain in the
Delaware Action. The parties are currently briefing issues that were
referred to the special master for decision.

On November 3, 1999, On-Line Technologies, Inc. ("On-Line"), which was
acquired by MKS in 2001, brought suit in federal district court in
Connecticut against Perkin-Elmer, Inc. and certain other defendants for
infringement of On-Line's patent related to its FTIR spectrometer product
and related claims. The suit sought injunctive relief and damages for
infringement. Perkin-Elmer, Inc. filed a counterclaim seeking invalidity
of the patent, costs and attorneys' fees. In June 2002, the defendants
filed a motion for summary judgment. In April 2003, the court granted the
motion and dismissed the case. MKS appealed this decision to the federal
circuit court of appeals. On October 13, 2004, the federal circuit court
of appeals reversed the lower court's dismissal of certain claims in the
case. Accordingly, the case has been remanded to the United States
District Court in Connecticut for further proceedings on the merits of the
remaining claims. On March 11, 2005, Perkin-Elmer, Inc. submitted to the
court a stipulation agreeing that they have infringed a specified claim of
On-Line's patent and filed a motion for summary judgment that such patent
claim is invalid. On April 6, 2005, On-Line filed a reply to the summary
judgment motion. The parties are awaiting the court's response to the
motion.

The Company is subject to other legal proceedings and claims, which have
arisen in the ordinary course of business.

In the opinion of management, the ultimate disposition of these matters
will not have a material adverse effect on the Company's results of
operations, financial condition or cash flows.

10) Restructuring Charges

As a result of the Company's various acquisitions from 2000 through 2002
and the downturn in the semiconductor capital equipment market which began
in 2000, the Company had redundant activities and excess manufacturing
capacity and office space. Therefore, in 2002 and continuing through the
first quarter of 2004, the Company implemented restructuring activities to
rationalize manufacturing operations and reduce operating expenses. As a
result of these actions, the Company recorded restructuring, asset
impairment charges and other charges of $2,726,000, $1,593,000 and
$437,000 in 2002, 2003 and 2004, respectively. The charges consisted of
$987,000 of severance costs related to workforce reductions, $2,810,000
related to consolidation of leased facilities, and asset impairment
charges of $959,000 primarily related to the impairment of an intangible
asset from the discontinuance of certain product development activities.
The fair value of the impaired intangible asset was determined using the
expected present value of future cash flows. The workforce reductions were
across all functional groups.

11



MKS INSTRUMENTS, INC.
NOTES TO CONSOLIDATED FINANCIAL STATEMENTS - (continued)
(Tables in thousands, except per share data)

During the three months ended March 31, 2005, the Company initiated a
restructuring plan related to its Berlin, Germany location. This
consolidation of activities included the reduction of 16 employees. The
total restructuring charge related to this consolidation was $454,000,
which consisted of $251,000 related to the repayment of a government grant
and $203,000 in severance costs. The Company expects to incur
approximately $100,000 in additional severance charges through the end of
2005, when the plan should be completed.

The following table sets forth the activity in the restructuring accruals
from December 31, 2004 to March 31, 2005:



Workforce Facility
Reductions Consolidations Other Total
---------- -------------- ----- -----

Balance as of December 31, 2004....................... $ 89 $1,532 $ - $1,621
Restructuring provision in first quarter.............. 203 - 251 454
Charges utilized in first quarter..................... (9) (110) - (119)
----- ------ ------ ------
Balance as of March 31, 2005.......................... $ 283 $1,422 $ 251 $1,956
===== ====== ====== ======


The remaining accruals for workforce reductions are expected to be paid by
December of 2005. The facilities consolidation charges will be paid over
the respective lease terms, the latest of which ends in 2008. The accruals
for severance costs and lease payments are recorded in Other accrued
expenses and Other liabilities in the consolidated balance sheets.

11) Product Warranties

The Company provides for the estimated costs to fulfill customer warranty
obligations upon the recognition of the related revenue. While the Company
engages in extensive product quality programs and processes, including
actively monitoring and evaluating the quality of its component suppliers,
the Company's warranty obligation is affected by product failure rates,
utilization levels, material usage, and supplier warranties on parts
delivered to the Company. Should actual product failure rates, utilization
levels, material usage, or supplier warranties on parts differ from the
Company's estimates, revisions to the estimated warranty liability would
be required.

Product warranty activities for the three months ended March 31 were as
follows:



2005 2004
---- ----

Balance at beginning of year......................................................... $7,601 $ 5,804
Provisions for product warranties during the first quarter .......................... 2,083 1,704
Direct charges to the warranty liability during the first quarter.................... (1,970) (1,146)
------ -------
Balance at the end of the first quarter.............................................. $7,714 $ 6,362
====== =======


12



MKS INSTRUMENTS, INC.

ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND
RESULTS OF OPERATIONS.

We believe that this Quarterly Report on Form 10-Q contains
"forward-looking statements" within the meaning of the Private Securities
Litigation Reform Act of 1995. When used herein, the words "believes,"
"anticipates," "plans," "expects," "estimates" and similar expressions are
intended to identify forward-looking statements. These forward-looking
statements reflect management's current opinions and are subject to certain
risks and uncertainties that could cause results to differ materially from those
stated or implied. We assume no obligation to update this information. Risks and
uncertainties include, but are not limited to, those discussed in the section in
this Report entitled "Factors That May Affect Future Results."

OVERVIEW

We are a leading worldwide provider of instruments, components, subsystems
and process control solutions that measure, control, power and monitor critical
parameters of semiconductor and other advanced manufacturing processes.

We are managed as one operating segment which is organized around three
product groups: Instruments and Control Systems, Power and Reactive Gas
Products, and Vacuum Products. Our products are derived from our core
competencies in pressure measurement and control, materials delivery, gas and
thin-film composition analysis, control and information management, power and
reactive gas generation and vacuum technology. Our products are used to
manufacture semiconductors and thin film coatings for diverse markets such as
flat panel displays, optical and magnetic storage media, architectural glass,
and electro-optical products. We also provide technologies for other markets,
including the medical imaging equipment market.

Our customers include semiconductor capital equipment manufacturers,
semiconductor device manufacturers, industrial manufacturing companies, medical
equipment manufacturers and university, government and industrial research
laboratories. For the three months ended March 31, 2005 and the full year ended
December 31, 2004, we estimate that approximately 72% and 74% of our net sales,
respectively, were to semiconductor capital equipment manufacturers and
semiconductor device manufacturers.

During the latter half of 2003 and continuing into the first half of 2004,
the semiconductor capital equipment market experienced a market upturn after a
downturn of almost three years. Starting in the fourth quarter of 2003, we
experienced an increase in orders and shipments and as a result have returned to
profitability. Beginning in the third quarter of 2004 and continuing through the
first quarter of 2005, our orders and sales have declined from the level
achieved in the second quarter of 2004. We currently expect our second quarter
2005 sales to be approximately the same as sales for the first quarter of 2005.
The semiconductor capital equipment industry is subject to rapid demand shifts
which are difficult to predict.

A portion of our sales is to operations in international markets.
International sales include sales by our foreign subsidiaries, but exclude
direct export sales. For the three months ended March 31, 2005 and full year
ended December 31, 2004, international sales accounted for approximately 39% and
34% of net sales, respectively.

CRITICAL ACCOUNTING POLICIES AND ESTIMATES

The preparation of our consolidated financial statements and related
disclosures in conformity with accounting principles generally accepted in the
United States of America requires management to make judgments, assumptions and
estimates that affect the amounts reported. There have been no material changes
in our critical accounting policies since December 31, 2004. See the discussion
of critical accounting policies in our Annual Report on Form 10-K for the year
ended December 31, 2004.

13



RESULTS OF OPERATIONS

The following table sets forth for the periods indicated the percentage of
total net sales of certain line items included in MKS' consolidated statements
of operations data.



Three Months Ended
March 31,
2005 2004
---- ----

Net sales.................................................................................. 100.0% 100.0%
Cost of sales.............................................................................. 61.3 59.2
----- -----
Gross profit............................................................................... 38.7 40.8
Research and development................................................................... 11.4 10.8
Selling, general and administrative........................................................ 18.7 15.2
Amortization of acquired intangible assets................................................. 2.9 2.8
Restructuring, asset impairment and other charges.......................................... 0.4 0.3
----- -----
Income from operations..................................................................... 5.3 11.7
Interest income, net....................................................................... 0.9 0.2
----- -----
Income before income taxes................................................................. 6.2 11.9
Provision for income taxes................................................................. 1.9 2.3
----- -----
Net income................................................................................. 4.3% 9.6%
===== =====


Net Sales (dollars in millions)



Three Months Ended March 31,
-----------------------------------
2005 2004 % Change
---- ---- --------

Net sales...................................................... $127.4 $133.0 (4.2)%


Net sales decreased $5.6 million mainly due to a decrease in worldwide
demand from our semiconductor capital equipment manufacturer and semiconductor
device manufacturer customers, which decreased $8.9 million or 8.9% compared to
the same period for the prior year. Offsetting this decrease was an increase of
$4.1 million or 18.7%, compared to the same period for the prior year, for other
non-semiconductor manufacturing applications which include, but are not limited
to, industrial manufacturing, magnetic resonance imaging (MRI) medical
equipment, biopharmaceutical manufacturing, and university, government and
industrial research laboratories.

Gross Profit



Three Months Ended March 31,
---------------------------------------
Percentage
2005 2004 Points Change
---- ---- -------------

Gross profit as percentage of net sales........................ 38.7% 40.8% (2.1)


Gross profit decreased mainly due to overhead costs increasing as a
percentage of sales. In the first quarter of 2004, gross profit reflected a
favorable impact of overhead absorption compared to the first quarter of 2005.
This was primarily due to a sequential increase in sales and inventory during
the three months ended March 31, 2004, related to a significant increase in
demand. Inventory increased by $12.9 million from $82.0 million at December 31,
2003 to $94.9 million at March 31, 2004 and decreased by $2.0 million during the
same period in 2005.

Research and Development (dollars in millions)



Three Months Ended March 31,
---------------------------------
2005 2004 % Change
---- ---- --------

Research and development expenses.............................. $14.5 $14.3 1.5%


14



Research and development expense increased $0.2 million mainly due to
increased compensation expense of $0.5 million as a result of higher staffing
levels and salary increases partially offset by a decrease in recruiting agency
fees of $0.2 million.

Our research and development is primarily focused on developing and
improving our instruments, components, subsystems and process control solutions
that measure, control, power and monitor critical parameters of semiconductor
and other advanced manufacturing processes.

We have hundreds of products and our research and development efforts
primarily consist of a large number of projects related to these products, none
of which is in and of itself material to us. Current projects typically have a
duration of 12 to 30 months depending upon whether the product is an enhancement
of existing technology or a new product. Our current initiatives include
projects to enhance the performance characteristics of older products, to
develop new products and to integrate various technologies into subsystems.
These projects support in large part the transition in the semiconductor
industry to larger wafer sizes and smaller integrated circuit geometries, which
require more advanced process control technology. Research and development
expenses consist primarily of salaries and related expense for personnel engaged
in research and development, fees paid to consultants, material costs for
prototypes and other expenses related to the design, development, testing and
enhancement of our products.

We believe that the continued investment in research and development and
ongoing development of new products are essential to the expansion of our
markets, and expect to continue to make significant investment in research and
development activities. We are subject to risks if products are not developed in
a timely manner, due to rapidly changing customer requirements and competitive
threats from other companies and technologies. Our success primarily depends on
our products being designed into new generations of equipment for the
semiconductor industry. We develop products that are technologically advanced so
that they are positioned to be chosen for use in each successive generation of
semiconductor capital equipment. If our products are not chosen to be designed
into our customers' products, our net sales may be reduced during the lifespan
of those products.

Selling, General and Administrative (dollars in millions)



Three Months Ended March 31,
-------------------------------
2005 2004 % Change
---- ---- --------

Selling, general and administrative expenses................ $23.8 $20.2 18.3%


Selling, general and administrative expenses increased $3.7 million mainly
due to a change of $1.0 million in foreign currency exchange expenses primarily
related to Asia, $0.7 million in higher compensation expense as a result of
higher staffing levels and salary increases, $0.7 million in higher consulting
fees primarily for IT related services, $0.6 million in higher insurance costs
and $0.5 million in increased facility costs.

Amortization of Acquired Intangible Assets (dollars in millions)



Three Months Ended March 31,
------------------------------
2005 2004 % Change
---- ---- --------

Amortization of acquired intangible assets.................. $3.7 $3.7 0.0%


Amortization expense for the three months ended March 31, 2005 and 2004,
respectively, represents amortization of identifiable intangible assets
resulting from our completed acquisitions.

Restructuring Charges (dollars in millions)



Three Months Ended March 31,
-------------------------------
2005 2004 % Change
---- ---- --------

Restructuring charges....................................... $0.5 $0.4 3.9%


15



As a result of our various acquisitions from 2000 through 2002 and the
downturn in the semiconductor capital equipment market which began in 2000, we
had redundant activities and excess manufacturing capacity and office space.
Therefore, in 2002 and continuing through the first quarter of 2004, we
implemented restructuring activities to rationalize manufacturing operations and
reduce operating expenses. As a result of these actions, we recorded
restructuring, asset impairment charges and other charges of $2.7 million, $1.6
million and $0.4 million in 2002, 2003 and 2004, respectively. The charges
consisted of $1.0 million of severance costs related to workforce reductions,
$2.8 million related to consolidation of leased facilities, and asset impairment
charges of $0.9 million primarily related to the impairment of an intangible
asset from the discontinuance of certain product development activities. The
fair value of the impaired intangible asset was determined using the expected
present value of future cash flows. The workforce reductions were across all
functional groups.

During the three months ended March 31, 2004, we completed our
restructuring activities initiated in 2002, when we exited a leased facility and
recorded a restructuring charge of $0.4 million. We implemented these
restructuring activities to rationalize manufacturing operations and to reduce
operating expenses.

During the three months ended March 31, 2005, we initiated a restructuring
plan related to our Berlin, Germany location. This consolidation of activities
included the reduction of 16 employees. The total restructuring charge related
to this consolidation was $0.5 million, which consisted of $0.3 million related
to the repayment of a government grant and $0.2 million in severance costs. We
expect to incur approximately $0.1 million in additional severance charges
through the end of 2005, when the plan should be completed.

The following table sets forth the activity in the restructuring accruals
from December 31, 2004 to March 31, 2005:



Workforce Facility
Reductions Consolidations Other Total
---------- -------------- ------ -----

Balance as of December 31, 2004....................... $ 89 $ 1,532 $ - $1,621
Restructuring provision in first quarter.............. 203 - 251 454
Charges utilized in first quarter..................... (9) (110) - (119)
---- ------- ------ ------
Balance as of March 31, 2005.......................... $283 $ 1,422 $ 251 $1,956
==== ======= ====== ======


The remaining accruals for workforce reductions are expected to be paid by
December 2005. The facilities consolidation charges will be paid over the
respective lease terms, the latest of which ends in 2008.

Interest Income, Net (dollars in millions)




Three Months Ended March 31,
-------------------------------
2005 2004 % Change
---- ---- --------

Interest income, net.................................. $1.1 $0.3 303.7%


Interest income increased $0.8 million mainly related to higher interest
rates on higher average investment balances in 2005.

Provision for Income Taxes (dollars in millions)




Three Months Ended March 31,
----------------------------
2005 2004
---- ----

Provision for income taxes............................ $2.5 $3.2


16



As a result of incurring significant operating losses from 2001 through
2003, we had established a full valuation allowance against our net deferred tax
assets. During the fourth quarter of 2004, after examining a number of factors,
including historical results and near term earnings projections, we determined
that it was more likely than not that we would realize all of our net deferred
tax assets, except for those related to certain state tax credits, and reduced
the valuation allowance accordingly. At March 31, 2005, we continued to maintain
a valuation allowance for certain state tax credits for which it was more likely
than not that they will not be realized.

Our effective tax rate for the quarter ending March 31, 2005 was 31%. The
effective tax rate is less than the statutory tax rate primarily due to the
profits of our international subsidiaries being taxed at rates lower than the
U.S. statutory tax rate.

During the first quarter of 2004, the U.S. taxable income was offset by
U.S. operating loss carryforwards and the tax provision was comprised of tax
expense from foreign operations and state taxes.

In the normal course of business, the Company and our subsidiaries are
examined by various tax authorities, including the Internal Revenue Service
("IRS"). The IRS is presently conducting an examination for the tax years 1999
through 2002 as part of its routine examinations of our income tax returns. The
outcome of this examination cannot be determined at this time since fieldwork is
still underway. We anticipate that the examination may be completed during
fiscal year 2005. Unfavorable settlement of any particular issue would require
the use of cash. Favorable resolution would result in a reduction to our
effective tax rate in the quarter of resolution. Any additional impact on our
liability for income taxes cannot presently be determined; however, we believe
our accrued income tax liabilities are adequate.

LIQUIDITY AND CAPITAL RESOURCES

Cash, cash equivalents and short-term investments totaled $244.9 million
at March 31, 2005 compared to $235.9 million at December 31, 2004. The primary
source of funds for the first three months of fiscal 2005 was cash provided by
operating activities of $9.9 million.

Net cash provided by operating activities of $9.9 million for the three
months ended March 31, 2005, resulted mainly from net income of $5.5 million and
non-cash charges of $6.7 million for depreciation and amortization, offset by an
increase in net operating assets and liabilities of $2.4 million. The net
increase in operating assets and liabilities is mainly caused by a $1.8 million
increase in accounts receivable and a decrease of $2.6 million in accrued
expenses and other current liabilities, primarily as a result of lower accrued
compensation, offset by an increase in accounts payable of $1.8 million. Net
cash provided by operating activities of $6.7 million for the three months ended
March 31, 2004 resulted mainly from net income of $12.7 million, non-cash
depreciation and amortization expenses of $6.9 million and an increase in
operating liabilities of $23.4 million, partially offset by an increase in
operating assets of $36.4 million. The increase in operating assets consisted
mainly of an increase in accounts receivable of $21.6 million due to the higher
shipments in the first quarter of 2004 as compared to the fourth quarter of
2003, and an increase in inventory of $12.3 million as a result of higher
production volumes in the first quarter of 2004 and expected shipments in the
second quarter of 2004. The increase in operating liabilities consisted
primarily of an increase in accounts payable, accrued expenses and other current
liabilities of $14.7 million resulting from increased production activity in the
first quarter, as well as an $8.6 million increase in income tax payable
consisting mainly of state and foreign taxes payable.

Net cash provided by investing activities of $4.5 million for the three
months ended March 31, 2005 resulted primarily from the net maturities of $6.5
million of available for sale investments offset by the purchase of property,
plant and equipment of $2.3 million primarily for investment in manufacturing
equipment and for the consolidation of our IT infrastructure. Net cash used in
investing activities of $24.2 million for the three months ended March 31, 2004
resulted mainly from the net purchases of $20.8 million of available for sale
investments, the purchase of property, plant and equipment of $4.2 million for
investments in manufacturing test equipment and for consolidation of our IT
infrastructure.

17



Net cash used in financing activities of $1.6 million for the three months
ended March 31, 2005 consisted primarily of $1.9 million in net payments for
short-term borrowings. Net cash provided by financing activities of $35.8
million for the three months ended March 31, 2004 consisted primarily of $32.5
million in net proceeds received from our common stock offering, $1.9 million in
proceeds from the exercise of stock options and purchases under the employee
stock purchase plan, and net proceeds of $1.9 million from short-term
borrowings, partially offset by $0.5 million of principal payments on long-term
debt.

We believe that our working capital, together with the cash anticipated to
be generated from operations, will be sufficient to satisfy our estimated
working capital and planned capital expenditure requirements through at least
the next 12 months.

To the extent permitted by Massachusetts law, our Restated Articles of
Organization, as amended, require us to indemnify any of our current or former
officers or directors or any person who has served or is serving in any capacity
with respect to any of our employee benefit plans. Because no claim for
indemnification has been pursued by any person covered by the relevant
provisions of our Restated Articles of Organization, we believe that the
estimated exposure for these indemnification obligations is currently minimal.
Accordingly, we have no liabilities recorded for these requirements as of March
31, 2005.

We also enter into agreements in the ordinary course of business which
include indemnification provisions. Pursuant to these agreements, we indemnify,
hold harmless and agree to reimburse the indemnified party, generally our
customers, for losses suffered or incurred by the indemnified party in
connection with any patent, any other intellectual property infringement claim,
and, in some instances, other claims, by any third party with respect to our
products. The term of these indemnification obligations is generally perpetual
after execution of the agreement. The maximum potential amount of future
payments we could be required to make under these indemnification agreements is,
in some instances, unlimited. We have never incurred costs to defend lawsuits or
settle claims related to these indemnification obligations. As a result, we
believe the estimated fair value of these obligations is minimal. Accordingly,
we have no liabilities recorded for these obligations as of March 31, 2005.

When as part of an acquisition, we acquire all of the stock or all of the
assets and liabilities of another company, we assume liability for certain
events or occurrences that took place prior to the date of acquisition. The
maximum potential amount of future payments we could be required to make for
such obligations is undeterminable at this time. Other than obligations recorded
as liabilities at the time of the acquisitions, historically we have not made
significant payments for these indemnifications. Accordingly, no liabilities
have been recorded for these obligations.

In conjunction with certain asset sales, we may provide routine
indemnifications whose terms range in duration and often are not explicitly
defined. Where appropriate, an obligation for such indemnifications is recorded
as a liability. Because the amount of liability under these types of
indemnifications are not explicitly stated, the overall maximum amount of the
obligation under such indemnifications cannot be reasonably estimated. Other
than obligations recorded as liabilities at the time of the asset sale,
historically we have not made significant payments for these indemnifications.

OFF-BALANCE SHEET ARRANGEMENTS

We do not have any financial partnerships with unconsolidated entities,
such as entities often referred to as structured finance, special purpose
entities or variable interest entities which are often established for the
purpose of facilitating off-balance sheet arrangements or other contractually
narrow or limited purposes. Accordingly, we are not exposed to any financing,
liquidity, market or credit risk that could arise if we had such relationships.

RECENTLY ISSUED ACCOUNTING PRONOUNCEMENTS

In March 2004, the Financial Accounting Standards Board ("FASB") issued
EITF Issue No. 03-1, "The Meaning of Other-Than-Temporary Impairment and Its
Application to Certain Investments" ("EITF 03-1"), which provides new guidance
for assessing impairment losses on debt and equity investments. Additionally,
EITF 03-1 includes new disclosure requirements for investments that are deemed
to be temporarily impaired. In September 2004, the FASB delayed the

18



accounting provisions of EITF 03-1; however, the disclosure requirements remain
effective and have been adopted for our fiscal year ended December 31, 2004. We
will evaluate the effect, if any, of EITF 03-1 when final guidance is released.

In November 2004, the FASB issued Statement of Financial Accounting
Standards No. 151, "Inventory Costs" ("SFAS 151"). SFAS 151 amends ARB No. 43,
Chapter 4, "Inventory Pricing." This statement clarifies the accounting for
abnormal amounts of idle facility expense, freight, handling costs, and wasted
material, and requires those items be recognized as current period charges
regardless of whether they meet the criterion of "so abnormal." In addition,
this statement requires that allocation of fixed production overheads to the
costs of conversion be based on the normal capacity of the production
facilities. SFAS 151 is effective for inventory costs incurred during fiscal
years beginning after June 15, 2005. We are currently assessing the potential
impact of SFAS 151.

In December 2004, the FASB issued Statement of Financial Accounting
Standards No. 123R, "Share-Based Payment" ("SFAS 123R"). SFAS 123R replaces SFAS
123 and supersedes APB 25. SFAS 123R focuses primarily on the accounting for
transactions in which an entity obtains employee services in share-based payment
transactions. SFAS 123R requires companies to recognize in the statement of
operations the cost of employee services received in exchange for awards of
equity instruments based on the grant-date fair value of those awards (with
limited exceptions). SFAS 123R was originally expected to be effective for us
beginning in our third quarter of fiscal 2005. In April 2005, the effective date
was amended by the Securities and Exchange Commission. As a result, SFAS 123R is
now effective for us as of the first annual period that begins after June 15,
2005. Accordingly, we will adopt SFAS 123R in our first quarter of fiscal 2006.
We expect to use the modified-prospective transition method and will not restate
prior periods for the adoption of SFAS 123R. Although we are currently
evaluating the provisions of SFAS 123R and its implications on our employee
benefit plans, we believe that the adoption of this standard, based on the terms
of the options outstanding at March 31, 2005, will have a material effect on our
net income in fiscal 2006.

FACTORS THAT MAY AFFECT FUTURE RESULTS

OUR BUSINESS DEPENDS SUBSTANTIALLY ON CAPITAL SPENDING IN THE SEMICONDUCTOR
INDUSTRY WHICH IS CHARACTERIZED BY PERIODIC FLUCTUATIONS THAT MAY CAUSE A
REDUCTION IN DEMAND FOR OUR PRODUCTS.

We estimate that approximately 72% of our net sales for the quarter ended
March 31, 2005 and 74%, 69%, and 70% of our net sales for the years ended
December 31, 2004, 2003 and 2002, respectively, were to semiconductor capital
equipment manufacturers and semiconductor device manufacturers, and we expect
that sales to such customers will continue to account for a substantial majority
of our sales. Our business depends upon the capital expenditures of
semiconductor device manufacturers, which in turn depend upon the demand for
semiconductors. Periodic reductions in demand for the products manufactured by
semiconductor capital equipment manufacturers and semiconductor device
manufacturers may adversely affect our business, financial condition and results
of operations.

Historically, the semiconductor market has been highly cyclical and has
experienced periods of overcapacity, resulting in significantly reduced demand
for capital equipment. For example, in 2001 through the first half of 2003, we
experienced a significant reduction in demand from OEM customers, and lower
gross margins due to reduced absorption of manufacturing overhead. In addition,
many semiconductor manufacturers have operations and customers in Asia, a region
that in past years has experienced serious economic problems including currency
devaluations, debt defaults, lack of liquidity and recessions. We cannot be
certain that semiconductor downturns will not continue or recur. A decline in
the level of orders as a result of any downturn or slowdown in the semiconductor
capital equipment industry could have a material adverse effect on our business,
financial condition and results of operations.

OUR QUARTERLY OPERATING RESULTS HAVE VARIED, AND ARE LIKELY TO CONTINUE TO VARY
SIGNIFICANTLY. THIS MAY RESULT IN VOLATILITY IN THE MARKET PRICE OF OUR COMMON
STOCK.

A substantial portion of our shipments occurs shortly after an order is
received and therefore we operate with a low level of backlog. As a result, a
decrease in demand for our products from one or more customers could occur with
limited advance notice and could have a material adverse effect on our results
of operations in any particular period. A significant percentage of our expenses
are relatively fixed and based in part on expectations of future net sales. The

19



inability to adjust spending quickly enough to compensate for any shortfall
would magnify the adverse impact of a shortfall in net sales on our results of
operations. Factors that could cause fluctuations in our net sales include:

- the timing of the receipt of orders from major customers;

- shipment delays;

- disruption in sources of supply;

- seasonal variations of capital spending by customers;

- production capacity constraints; and

- specific features requested by customers.

In addition, our quarterly operating results may be adversely affected due
to charges incurred in a particular quarter, for example, relating to inventory
obsolescence, bad debt or asset impairments.

As a result of the factors discussed above, it is likely that we may in
the future experience quarterly or annual fluctuations and that, in one or more
future quarters, our operating results may fall below the expectations of public
market analysts or investors. In any such event, the price of our common stock
could decline significantly.

THE LOSS OF NET SALES TO ANY ONE OF OUR MAJOR CUSTOMERS WOULD LIKELY HAVE A
MATERIAL ADVERSE EFFECT ON US.

Our top ten customers accounted for approximately 49%, 42%, and 49% of our
net sales for the years ended December 31, 2004, 2003 and 2002, respectively.
The loss of a major customer or any reduction in orders by these customers,
including reductions due to market or competitive conditions, would likely have
a material adverse effect on our business, financial condition and results of
operations. During the years ended December 31, 2004, 2003 and 2002, one
customer, Applied Materials, accounted for approximately 20%, 18%, and 23%,
respectively, of our net sales. None of our significant customers, including
Applied Materials, has entered into an agreement requiring it to purchase any
minimum quantity of our products. The demand for our products from our
semiconductor capital equipment customers depends in part on orders received by
them from their semiconductor device manufacturer customers.

Attempts to lessen the adverse effect of any loss or reduction of net
sales through the rapid addition of new customers could be difficult because
prospective customers typically require lengthy qualification periods prior to
placing volume orders with a new supplier. Our future success will continue to
depend upon:

- our ability to maintain relationships with existing key customers;

- our ability to attract new customers;

- our ability to introduce new products in a timely manner for
existing and new customers; and

- the success of our customers in creating demand for their capital
equipment products which incorporate our products.

AS PART OF OUR BUSINESS STRATEGY, WE HAVE ENTERED INTO AND MAY ENTER INTO OR
SEEK TO ENTER INTO BUSINESS COMBINATIONS AND ACQUISITIONS THAT MAY BE DIFFICULT
AND COSTLY TO INTEGRATE, DISRUPT OUR BUSINESS, DILUTE STOCKHOLDER VALUE OR
DIVERT MANAGEMENT ATTENTION.

We made several acquisitions in the years 2000 through 2002. As a part of
our business strategy, we may enter into additional business combinations and
acquisitions. Acquisitions are typically accompanied by a number of risks,
including the difficulty of integrating the operations and personnel of the
acquired companies, the potential disruption of our ongoing business and
distraction of management, expenses related to the acquisition and potential
unknown liabilities

20



associated with acquired businesses. If we are not successful in completing
acquisitions that we may pursue in the future, we may be required to reevaluate
our growth strategy, and we may incur substantial expenses and devote
significant management time and resources in seeking to complete proposed
acquisitions that will not generate benefits for us.

In addition, with future acquisitions, we could use substantial portions
of our available cash as all or a portion of the purchase price. We could also
issue additional securities as consideration for these acquisitions, which could
cause significant stockholder dilution. Our prior acquisitions and any future
acquisitions may not ultimately help us achieve our strategic goals and may pose
other risks to us.

As a result of our previous acquisitions, we have added several different
decentralized operating and accounting systems, resulting in a complex reporting
environment. We expect that we will need to continue to modify our accounting
policies, internal controls, procedures and compliance programs to provide
consistency across all our operations. In order to increase efficiency and
operating effectiveness and improve corporate visibility into our decentralized
operations, we are currently in the planning and design phase of implementing a
new worldwide Enterprise Resource Planning ("ERP") system. We expect to
implement the ERP system by converting our operations in phases over the next
few years, beginning in the second half of 2005. Although we have a detailed
plan to accomplish the ERP implementation, we may risk potential disruption of
our operations during the conversion periods, the implementation could require
significantly more management time than currently estimated and we could incur
significantly higher implementation costs than currently estimated.

AN INABILITY TO CONVINCE SEMICONDUCTOR DEVICE MANUFACTURERS TO SPECIFY THE USE
OF OUR PRODUCTS TO OUR CUSTOMERS, THAT ARE SEMICONDUCTOR CAPITAL EQUIPMENT
MANUFACTURERS, WOULD WEAKEN OUR COMPETITIVE POSITION.

The markets for our products are highly competitive. Our competitive
success often depends upon factors outside of our control. For example, in some
cases, particularly with respect to mass flow controllers, semiconductor device
manufacturers may direct semiconductor capital equipment manufacturers to use a
specified supplier's product in their equipment. Accordingly, for such products,
our success will depend in part on our ability to have semiconductor device
manufacturers specify that our products be used at their semiconductor
fabrication facilities. In addition, we may encounter difficulties in changing
established relationships of competitors that already have a large installed
base of products within such semiconductor fabrication facilities.

IF OUR PRODUCTS ARE NOT DESIGNED INTO SUCCESSIVE GENERATIONS OF OUR CUSTOMERS'
PRODUCTS, WE WILL LOSE SIGNIFICANT NET SALES DURING THE LIFESPAN OF THOSE
PRODUCTS.

New products designed by semiconductor capital equipment manufacturers
typically have a lifespan of five to ten years. Our success depends on our
products being designed into new generations of equipment for the semiconductor
industry. We must develop products that are technologically advanced so that
they are positioned to be chosen for use in each successive generation of
semiconductor capital equipment. If customers do not choose our products, our
net sales may be reduced during the lifespan of our customers' products. In
addition, we must make a significant capital investment to develop products for
our customers well before our products are introduced and before we can be sure
that we will recover our capital investment through sales to the customers in
significant volume. We are thus also at risk during the development phase that
our products may fail to meet our customers' technical or cost requirements and
may be replaced by a competitive product or alternative technology solution. If
that happens, we may be unable to recover our development costs.

THE SEMICONDUCTOR INDUSTRY IS SUBJECT TO RAPID DEMAND SHIFTS WHICH ARE DIFFICULT
TO PREDICT. AS A RESULT, OUR INABILITY TO EXPAND OUR MANUFACTURING CAPACITY IN
RESPONSE TO THESE RAPID SHIFTS MAY CAUSE A REDUCTION IN OUR MARKET SHARE.

Our ability to increase sales of certain products depends in part upon our
ability to expand our manufacturing capacity for such products in a timely
manner. If we are unable to expand our manufacturing capacity on a timely basis
or to manage such expansion effectively, our customers could implement our
competitors' products and, as a result, our market share could be reduced.
Because the semiconductor industry is subject to rapid demand shifts which are
difficult to foresee, we may not be able to increase capacity quickly enough to
respond to a rapid increase in demand.

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Additionally, capacity expansion could increase our fixed operating expenses and
if sales levels do not increase to offset the additional expense levels
associated with any such expansion, our business, financial condition and
results of operations could be materially adversely affected.

WE OPERATE IN A HIGHLY COMPETITIVE INDUSTRY.

The market for our products is highly competitive. Principal competitive
factors include:

- historical customer relationships;

- product quality, performance and price;

- breadth of product line;

- manufacturing capabilities; and

- customer service and support.

Although we believe that we compete favorably with respect to these
factors, there can be no assurance that we will continue to do so. We encounter
substantial competition in most of our product lines. Certain of our competitors
may have greater financial and other resources than we have. In some cases,
competitors are smaller than we are, but well established in specific product
niches. We may encounter difficulties in changing established relationships of
competitors with a large installed base of products at such customers'
fabrication facilities. In addition, our competitors can be expected to continue
to improve the design and performance of their products. There can be no
assurance that competitors will not develop products that offer price or
performance features superior to those of our products.

SALES TO FOREIGN MARKETS CONSTITUTE A SUBSTANTIAL PORTION OF OUR NET SALES;
THEREFORE, OUR NET SALES AND RESULTS OF OPERATIONS COULD BE ADVERSELY AFFECTED
BY DOWNTURNS IN ECONOMIC CONDITIONS IN COUNTRIES OUTSIDE OF THE UNITED STATES.

International sales include sales by our foreign subsidiaries, but exclude
direct export sales. International sales accounted for approximately 34%, 41%,
and 36% of net sales for the years ended December 31, 2004, 2003 and 2002,
respectively, a significant portion of which were sales to Japan.

We anticipate that international sales will continue to account for a
significant portion of our net sales. In addition, certain of our key domestic
customers derive a significant portion of their revenues from sales in
international markets. Therefore, our sales and results of operations could be
adversely affected by economic slowdowns and other risks associated with
international sales.

RISKS RELATING TO OUR INTERNATIONAL OPERATIONS COULD ADVERSELY AFFECT OUR
OPERATING RESULTS.

We have substantial international sales, service and manufacturing
operations in Europe and Asia, which expose us to foreign operational and
political risks that may harm our business. Our international operations are
subject to inherent risks, which may adversely affect us, including:

- political and economic instability in countries where we have sales,
service and manufacturing operations;

- fluctuations in the value of currencies and high levels of
inflation, particularly in Asia and Europe;

- changes in labor conditions and difficulties in staffing and
managing foreign operations, including, but not limited to, labor
unions;

- greater difficulty in collecting accounts receivable and longer
payment cycles;

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- burdens and costs of compliance with a variety of foreign laws;

- increases in duties and taxation;

- imposition of restrictions on currency conversion or the transfer of
funds;

- changes in export duties and limitations on imports or exports;

- expropriation of private enterprises; and

- unexpected changes in foreign regulations.

If any of these risks materialize, our operating results may be adversely
affected.

UNFAVORABLE CURRENCY EXCHANGE RATE FLUCTUATIONS MAY LEAD TO LOWER OPERATING
MARGINS, OR MAY CAUSE US TO RAISE PRICES WHICH COULD RESULT IN REDUCED SALES.

Currency exchange rate fluctuations could have an adverse effect on our
net sales and results of operations and we could experience losses with respect
to our hedging activities. Unfavorable currency fluctuations could require us to
increase prices to foreign customers which could result in lower net sales by us
to such customers. Alternatively, if we do not adjust the prices for our
products in response to unfavorable currency fluctuations, our results of
operations could be adversely affected. In addition, most sales made by our
foreign subsidiaries are denominated in the currency of the country in which
these products are sold and the currency they receive in payment for such sales
could be less valuable at the time of receipt as a result of exchange rate
fluctuations. We enter into forward exchange contracts and local currency
purchased options to reduce currency exposure arising from intercompany sales of
inventory. However, we cannot be certain that our efforts will be adequate to
protect us against significant currency fluctuations or that such efforts will
not expose us to additional exchange rate risks.

KEY PERSONNEL MAY BE DIFFICULT TO ATTRACT AND RETAIN.

Our success depends to a large extent upon the efforts and abilities of a
number of key employees and officers, particularly those with expertise in the
semiconductor manufacturing and similar industrial manufacturing industries. The
loss of key employees or officers could have a material adverse effect on our
business, financial condition and results of operations. We believe that our
future success will depend in part on our ability to attract and retain highly
skilled technical, financial, managerial and marketing personnel. We cannot be
certain that we will be successful in attracting and retaining such personnel.

OUR PROPRIETARY TECHNOLOGY IS IMPORTANT TO THE CONTINUED SUCCESS OF OUR
BUSINESS. OUR FAILURE TO PROTECT THIS PROPRIETARY TECHNOLOGY MAY SIGNIFICANTLY
IMPAIR OUR COMPETITIVE POSITION.

As of December 31, 2004, we owned 221 U.S. patents, 156 foreign patents
and had 91 pending U.S. patent applications. Although we seek to protect our
intellectual property rights through patents, copyrights, trade secrets and
other measures, we cannot be certain that:

- we will be able to protect our technology adequately;

- competitors will not be able to develop similar technology
independently;

- any of our pending patent applications will be issued;

- intellectual property laws will protect our intellectual property
rights; or

- third parties will not assert that our products infringe patent,
copyright or trade secrets of such parties.

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PROTECTION OF OUR INTELLECTUAL PROPERTY RIGHTS MAY RESULT IN COSTLY LITIGATION.

Litigation may be necessary in order to enforce our patents, copyrights or
other intellectual property rights, to protect our trade secrets, to determine
the validity and scope of the proprietary rights of others or to defend against
claims of infringement. We have been in the past, and currently are, involved in
lawsuits enforcing and defending our intellectual property rights and may be
involved in such litigation in the future. Such litigation could result in
substantial costs and diversion of resources and could have a material adverse
effect on our business, financial condition and results of operations.

We may need to expend significant time and expense to protect our
intellectual property regardless of the validity or successful outcome of such
intellectual property claims. If we lose any litigation, we may be required to
seek licenses from others or change, stop manufacturing or stop selling some of
our products.

THE MARKET PRICE OF OUR COMMON STOCK HAS FLUCTUATED AND MAY CONTINUE TO
FLUCTUATE FOR REASONS OVER WHICH WE HAVE NO CONTROL.

The stock market has from time to time experienced, and is likely to
continue to experience, extreme price and volume fluctuations. Prices of
securities of technology companies have been especially volatile and have often
fluctuated for reasons that are unrelated to the operating performance of the
companies. The market price of shares of our common stock has fluctuated greatly
since our initial public offering and could continue to fluctuate due to a
variety of factors. In the past, companies that have experienced volatility in
the market price of their stock have been the objects of securities class action
litigation. If we were the object of securities class action litigation, it
could result in substantial costs and a diversion of our management's attention
and resources.

OUR DEPENDENCE ON SOLE, LIMITED SOURCE SUPPLIERS, AND INTERNATIONAL SUPPLIERS,
COULD AFFECT OUR ABILITY TO MANUFACTURE PRODUCTS AND SYSTEMS.

We rely on sole, limited source suppliers, and international suppliers,
for a few of our components and subassemblies that are critical to the
manufacturing of our products. This reliance involves several risks, including
the following:

- the potential inability to obtain an adequate supply of required
components;

- reduced control over pricing and timing of delivery of components;
and

- the potential inability of our suppliers to develop technologically
advanced products to support our growth and development of new
systems.

We believe that in time we could obtain and qualify alternative sources
for most sole, limited source and international supplier parts. Seeking
alternative sources of the parts could require us to redesign our systems,
resulting in increased costs and likely shipping delays. We may be unable to
redesign our systems, which could result in further costs and shipping delays.
These increased costs would decrease our profit margins if we could not pass the
costs to our customers. Further, shipping delays could damage our relationships
with current and potential customers and have a material adverse effect on our
business and results of operations.

WE ARE SUBJECT TO GOVERNMENTAL REGULATIONS. IF WE FAIL TO COMPLY WITH THESE
REGULATIONS, OUR BUSINESS COULD BE HARMED.

We are subject to federal, state, local and foreign regulations, including
environmental regulations and regulations relating to the design and operation
of our products. We must ensure that the affected products meet a variety of
standards, many of which vary across the countries in which our systems are
used. For example, the European Union has published directives specifically
relating to power supplies. In addition, the European Union has issued
directives relating to future regulation of recycling and hazardous substances,
which may be applicable to our products, or which some customers may voluntarily
elect to adhere to. We must comply with any applicable directive in order to
ship affected

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products into countries that are members of the European Union. We believe we
are in compliance with current applicable regulations, directives and standards
and have obtained all necessary permits, approvals, and authorizations to
conduct our business. However, compliance with future regulations, directives
and standards could require us to modify or redesign certain systems, make
capital expenditures or incur substantial costs. If we do not comply with
current or future regulations, directives and standards:

- we could be subject to fines;

- our production could be suspended; or

- we could be prohibited from offering particular systems in specified
markets.

CERTAIN STOCKHOLDERS HAVE A SUBSTANTIAL INTEREST IN US AND MAY BE ABLE TO EXERT
SUBSTANTIAL INFLUENCE OVER OUR ACTIONS.

As of January 31, 2005, John R. Bertucci, our Chairman and Chief Executive
Officer and certain members of his family, in the aggregate, beneficially owned
approximately 18% of our outstanding common stock. As a result, these
stockholders, acting together, are able to exert substantial influence over our
actions. Pursuant to the acquisition of the ENI Business of Emerson Electric Co.
("Emerson"), we issued approximately 12,000,000 shares of common stock to
Emerson and its wholly owned subsidiary, Astec America, Inc. Emerson owned
approximately 19% of our outstanding common stock as of January 31, 2005, and
James G. Berges, the President and a director of Emerson, is a member of our
board of directors. Accordingly, Emerson is able to exert substantial influence
over our actions.

SOME PROVISIONS OF OUR RESTATED ARTICLES OF ORGANIZATION, AS AMENDED, OUR
AMENDED AND RESTATED BY-LAWS AND MASSACHUSETTS LAW COULD DISCOURAGE POTENTIAL
ACQUISITION PROPOSALS AND COULD DELAY OR PREVENT A CHANGE IN CONTROL OF US.

Anti-takeover provisions could diminish the opportunities for stockholders
to participate in tender offers, including tender offers at a price above the
then current market price of the common stock. Such provisions may also inhibit
increases in the market price of the common stock that could result from
takeover attempts. For example, while we have no present plans to issue any
preferred stock, our board of directors, without further stockholder approval,
may issue preferred stock that could have the effect of delaying, deterring or
preventing a change in control of us. The issuance of preferred stock could
adversely affect the voting power of the holders of our common stock, including
the loss of voting control to others. In addition, our amended and restated
by-laws provide for a classified board of directors consisting of three classes.
The classified board could also have the effect of delaying, deterring or
preventing a change in control of us.

ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK.

Information concerning market risk is contained in the Management's
Discussion and Analysis of Financial Condition and Results of Operations
contained in our Annual Report on Form 10-K filed with the Securities and
Exchange Commission on March 16, 2005. There were no material changes in our
exposure to market risk from December 31, 2004.

ITEM 4. CONTROLS AND PROCEDURES.

a) Effectiveness of disclosure controls and procedures.

MKS' management, with the participation of our chief executive officer and
chief financial officer, evaluated the effectiveness of our disclosure controls
and procedures as of March 31, 2005. The term "disclosure controls and
procedures," as defined in Rules 13a-15(e) and 15d-15(e) under the Securities
Exchange Act of 1934, as amended ("the Exchange Act"), means controls and other
procedures of a company that are designed to ensure that information required to
be disclosed by the company in the reports that it files or submits under the
Exchange Act is recorded, processed, summarized and reported, within the time
periods specified in the SEC's rules and forms. Disclosure controls and

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procedures include, without limitation, controls and procedures designed to
ensure that information required to be disclosed by a company in the reports
that it files or submits under the Exchange Act is accumulated and communicated
to the company's management, including its principal executive and principal
financial officers, as appropriate to allow timely decisions regarding required
disclosure. Management recognizes that any controls and procedures, no matter
how well designed and operated, can provide only reasonable assurance of
achieving their objectives and management necessarily applies its judgment in
evaluating the cost-benefit relationship of possible controls and procedures.
Based on the evaluation of our disclosure controls and procedures as of March
31, 2005, our chief executive officer and chief financial officer concluded
that, as of such date, our disclosure controls and procedures were effective at
the reasonable assurance level.

b) Changes in internal control over financial reporting.

There was no change in our internal control over financial reporting (as
defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act) that occurred
during the quarter ended March 31, 2005 that has materially affected, or is
reasonably likely to materially affect, our internal control over financial
reporting.

PART II. PERIOD OTHER INFORMATION

ITEM 1. LEGAL PROCEEDINGS.

On April 3, 2003, Advanced Energy Industries, Inc. ("Advanced Energy")
filed suit against us in federal district court in Colorado ("Colorado Action"),
seeking a declaratory judgment that Advanced Energy's Xstream product does not
infringe three patents held by our subsidiary, Applied Science and Technology,
Inc. ("ASTeX"). On May 14, 2003, we brought suit in federal district court in
Delaware against Advanced Energy for infringement of five ASTeX patents (the
"Delaware Action"), including the three patents at issue in the Colorado Action.
We sought injunctive relief and damages for Advanced Energy's infringement. On
December 24, 2003, the Colorado court granted our motion to transfer Advanced
Energy's Colorado Action to Delaware. In connection with the jury trial, the
parties agreed to present the jury with representative claims from three of the
five ASTeX patents. On July 23, 2004, the jury found that Advanced Energy
infringed all three patents. On March 31 and April 5, 2005, the Court issued
orders concerning a number of pre- and post-trial motions. Several other
post-trial motions remain pending. The Court referred several of the pending
motions to a special master for decision, and the Court scheduled a hearing for
May 26, 2005 to address scheduling issues, including the trial of any remaining
issues in the Delaware Action. We expect that the second phase of trial will
address our claims of damages and willful infringement against Advanced Energy
and will also address certain of Advanced Energy's affirmative defenses that
remain in the Delaware Action. The parties are currently briefing issues that
were referred to the special master for decision.

On November 3, 1999, On-Line Technologies, Inc. ("On-Line"), which was
acquired by us in 2001, brought suit in federal district court in Connecticut
against Perkin-Elmer, Inc. and certain other defendants for infringement of
On-Line's patent related to its FTIR spectrometer product and related claims.
The suit sought injunctive relief and damages for infringement. Perkin-Elmer,
Inc. filed a counterclaim seeking invalidity of the patent, costs and attorneys'
fees. In June 2002, the defendants filed a motion for summary judgment. In April
2003, the court granted the motion and dismissed the case. We appealed this
decision to the federal circuit court of appeals. On October 13, 2004, the
federal circuit court of appeals reversed the lower court's dismissal of certain
claims in the case. Accordingly, the case has been remanded to the United States
District Court in Connecticut for further proceedings on the merits of the
remaining claims. On March 11, 2005, Perkin-Elmer, Inc. submitted to the court a
stipulation agreeing that they have infringed a specified claim of On-Line's
patent and filed a motion for summary judgment that such patent claim is
invalid. On April 6, 2005, On-Line filed a reply to the summary judgment motion.
The parties are awaiting the court's response to the motion.

We are subject to other legal proceedings and claims, which have arisen in
the ordinary course of business.

26



In the opinion of management, the ultimate disposition of these matters
will not have a material adverse effect on our results of operations, financial
condition or cash flows.

ITEM 6. EXHIBITS.



Exhibit No. Exhibit Description
- ----------- -------------------

+10.1(1) Global Supply Agreement between MKS Instruments, Inc. and
Applied Materials, Inc., dated April 21, 2005

10.2*(1) Employment Agreement dated April 25, 2005, between MKS
Instruments, Inc. and Gerald G. Colella

31.1 Certification of Principal Executive Officer pursuant to Rule
13a-14(a)/Rule 15d-14(a) of the Securities Exchange Act of
1934, as amended

31.2 Certification of Principal Financial Officer pursuant to Rule
13a-14(a)/Rule 15d-14(a) of the Securities Exchange Act of
1934, as amended

32.1 Certification of Chief Executive Officer and Chief Financial
Officer pursuant to 18 U.S.C. Section 1350, as adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of 2002


- -------------
(1) Incorporated by reference to one of the Registrant's Current Reports on
Form 8-K filed with the Securities and Exchange Commission on April 27,
2005.

+ Confidential treatment requested as to certain portions which portions
have been separately filed with the Securities and Exchange Commission.

* Management contract or compensatory plan arrangement.

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the
undersigned thereunto duly authorized.

MKS INSTRUMENTS, INC.

May 5, 2005 By: /s/ Ronald C. Weigner
---------------------------
Ronald C. Weigner
Vice President and Chief
Financial Officer
(Principal Financial Officer)

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