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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 10-Q

QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE
SECURITIES EXCHANGE ACT OF 1934.

For the Quarterly Period Ended June 30, 2002

Commission File Number 0-18044

PROCYTE CORPORATION
(Exact name of the registrant as specified in its charter)

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.

Yes ý No o

As of August 8, 2002, there were issued and outstanding 15,720,720 shares of common stock, par value $.01 per share.

ProCyte Corporation
Index

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Part I—Financial Information

Item 1. Condensed Financial Statements (unaudited)

Balance Sheets—as of June 30, 2002 and December 31, 2001

See notes to condensed financial statements

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Statements of Operations—Three & Six Months Ended June 30, 2002 and 2001

See notes to condensed financial statements

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Statements of Cash Flows—Six Months Ended June 30, 2002 and 2001

See notes to condensed financial statements

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Statements of Stockholders' Equity—Six Months Ended June 30, 2002 and 2001

See notes to condensed financial statements

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ProCyte Corporation
Notes to Condensed Financial Statements

1.    Basis of Presentation

The accompanying unaudited condensed financial statements of ProCyte Corporation ("ProCyte" or the "Company") for the three-month and six-month periods ended June 30, 2002 and 2001 have been prepared by the Company in accordance with accounting principles generally accepted in the United States of America for interim financial information and the instructions to Form 10-Q and Article 10 of Regulation S-X. Pursuant to such rules and regulations, the condensed financial statements do not include all of the information and footnotes required by accounting principles generally accepted in the United States of America for audited financial statements. Accordingly, this financial information should be read in conjunction with the complete audited financial statements, including the notes thereto, which are included in the Company's Annual Report on Form 10-K for the year ended December 31, 2001. In the opinion of management, all material adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation of the financial statements have been included. Interim results are not necessarily indicative of the results that may be expected for the year.

In April 2002, the Financial Accounting Standards Board (FASB) issued SFAS No. 145, Rescission of FASB Statements No. 4, 44, and 64, Amendment of FASB Statement No. 13, and Technical Corrections. This Statement rescinds SFAS No. 4, Reporting Gains and Losses from Extinguishment of Debt, and an amendment of that statement, SFAS No. 64, Extinguishments of Debt Made to Satisfy Sinking-Fund Requirements. SFAS No. 145 also rescinds SFAS No. 44, Accounting for Intangible Assets of Motor Carriers. SFAS No. 145 amends SFAS No. 13, Accounting for Leases, to eliminate an inconsistency between the required accounting for sale-leaseback transactions and the required accounting for certain lease modifications that have economic effects that are similar to sale-leaseback transactions. SFAS No. 145 also amends other existing authoritative pronouncements to make various technical corrections, clarify meanings, or describe their applicability under changed conditions. Certain provisions of SFAS No. 145 will be adopted by the Company on January 1, 2003. The Company does not anticipate that adoption of these provisions will have a material effect on its financial position or results of operations. The Company has adopted the provisions of SFAS No. 145 that are effective for financial statements issued after May 15, 2002. There was no impact on the Company's financial position or results of operations as a result of the adoption of these provisions.

In July 2002, the FASB issued SFAS No. 146, Accounting for Costs Associated with Exit or Disposal Activities. This standard requires companies to recognize costs associated with exit or disposal activities when they are incurred rather than at the date of a commitment to an exit or disposal plan. Examples of costs covered by the standard include lease termination costs and certain employee severance costs that are associated with a restructuring, discontinued operation, plant closing, or other exit or disposal activity. SFAS No. 146 is to be applied prospectively to exit or disposal activities initiated after December 31, 2002.

2.    Accounts Receivable

The Company shipped several large orders to its licensing partners at the end of June, which increased its accounts receivable balance at June 30, 2002 significantly as compared to the balance at December 31, 2001. Two Customers represented 36.5% and 13.7% of the outstanding accounts receivable balance at June 30, 2002.

During the six months ended June 30, 2002, the Company wrote-off uncollectable balances related to certain terminated licensing agreements. The Company has provided a reserve for uncollectable receivables in the amount of $83,312 at June 30, 2002 and $243,213 at December 31, 2001. The bad debt expense, net of recoveries, was ($12,039) and $2,760 for the quarters ended June 30, 2002 and

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2001, respectively, and ($6,910) and $10,210 for the six months ended in June 30, 2002 and 2001, respectively.

3.    Inventory

Inventory after consideration for excess and obsolete items consisted of the following:

4.    Property and Equipment

Property and equipment consisted of the following:

5.    Intangible Assets

At June 30, 2002 and December 31, 2001, intangible assets are shown net of accumulated amortization of $1,055,442 and $1,047,438, respectively. On January 1, 2002, the Company implemented the guidance of Statement of Financial Accounting Standards (SFAS) No. 142 "Goodwill and Other Intangible Assets" in recognizing certain intangibles as goodwill and assessing potential future impairments of goodwill. The Company performed an annual test on the value of its goodwill under the guidance of SFAS 142 on March 31, 2002, and did not identify the need to recognize any impairment of value at that time. There were no events in the second quarter, which would cause the Company to change its valuation as of June 30, 2002. This analysis was based on one reportable unit. All of Goodwill is deemed to be associated with ProCyte's overall business operations. The Company's amortization expense for goodwill was $61,250 and $122,500 in the quarter and six months ended June 30, 2001, respectively. The net loss for the quarter and the six months then ended would have been $303,391 and $743,806, or ($0.02) and ($0.05) net loss per share, if goodwill had not been amortized.

6.    Federal Income Taxes

The provision for income taxes consisted of the following components:

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The provision for income taxes differs from the amount computed by applying the statutory federal income tax rate to income before taxes as follows:

The tax effect of temporary differences and net operating loss carry forward that give rise to the Company's deferred tax assets and liabilities are as follows:

At June 30, 2002 and December 31, 2001, the Company provided full valuation allowance for its net deferred tax assets. The Company believes sufficient uncertainty exists regarding the realizability of the deferred tax assets. The net change in the valuation allowance during the six months ended June 30, 2002 and year ended December 31, 2001, were ($367,536) and $600,000, respectively.

As of June 30, 2002, the Company's U.S. federal net operating loss and general business credit carry forward for income tax purposes were approximately $25,733,367. If not utilized, the federal net operating loss carry forward and tax credits carry forward will expire between 2002 and 2021. Changes in ownership, as defined by Section 382 of the IRC, may limit the amount of net operating loss carry forward used in any one year.

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7.    Stockholders' Equity

Information relating to stock options granted, exercised, canceled and currently exercisable is as follows:

At June 30, 2002, the Company's 1996 Stock Option Plan had 628,162 shares of the Company's common stock available, which included the 750,000 shares approved for the plan at the Company' annual shareholders meeting on May 21, 2002.

The Company issued 7,052 shares on July 1, 2002, in payment of the Board of Director retainers for the second quarter. As of August 8, 2002, the Company's 1998 Non-employee Director Stock Plan had 155,475 shares of the Company's common stock available.

The Company granted 10,000 stock options on February 21, 2002 and 10,000 stock options on May 20, 2002 in exchange for advisory services from two non-employee consultants. The February and May grants, respectively, oblige the Company to issue 10,000 common stock shares at $1.33 and $1.83, the market price on the dates of grant. Both grants become fully vested one year after their date of issuance. The fair value of the February and May grants was determined to be $6,448 and $11,005, respectively, using the Black-Scholes option pricing model. The assumptions used in the model for the February and May grants, respectively, were a risk-free interest rate of 3.84% and 3.92%, 67% and 61% stock price volatility, and no dividends over the two year expected lives. The fair values are reported as deferred compensation in Stockholders' Equity, and are being amortized as an operating expense over the expected lives.

The Company issued three common stock warrants for 100,000 shares on May 26, 1999 in exchange for services. The three warrants oblige the Company to issue 33,334 shares at $0.6875 per share, the market price on the grant date, 33,333 shares at $1.6875 and 33,333 shares at $2.6875. Each of the warrants has a five-year life and is fully vested. The fair value of these warrants was determined to be $90,117 using the Black-Scholes option-pricing model and was expensed in 1999. The assumptions used in the model were a risk-free interest rate of 4.08%, an expected life of five years, 98% stock price volatility and no dividends over the expected life. On January 2, 2002, the first warrant for 33,334 shares was exercised.

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8.    Related Party Disclosure

The Company owns a promissory note in the principle amount of $2,000,000 from Emerald Pharmaceutical L.P., which it received as partial consideration for the sale of its contract manufacturing operation in 2001. The note is secured by the manufacturing assets sold and bears interest equal to the effective yield on the 10 Year US Treasury Note, which is adjusted quarterly. The average yield for the quarter and six months ended June 30, 2002 was 5.39% and 5.21%, respectively. Emerald will begin making annual principal payments of $285,714 in July 2005. The Company also received a minority limited partnership interest in Emerald as part of consideration received in the sale. As part of the agreement, ProCyte leases a portion of its current 32,750 square foot leased facility, including existing leasehold improvements, to Emerald. Also included in the proceeds is $1,627,906, which is being recognized over the term of the lease for Emerald's use of the leasehold improvements. ProCyte engages Emerald Pharmaceutical L.P. to do certain manufacturing and other quality and analytical services. Emerald billed ProCyte a total of $61,040 and $193,701 for the services during the quarter and six months ended June 30, 2002, respectively.

One of the Company's Directors serves as Chairman and Chief Executive Officer of one of ProCyte's customers. The customer purchased $186,755 and $308,544 in product during the quarter and six months ended June 30, 2002, respectively. On June 30, 2002 the customer owed ProCyte $253,237.

At June 30, 2002 and December 31, 2001, respectively, an Officer owed the Company $103,898 and $117,904, respectively, including accrued interest at 4.28% under the terms of a promissory note dated December 16, 1998. In the second quarter of 2002, the Compensation Committee of the Board of Directors agreed to extend the note's due date an additional two years to June 30, 2004.

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Item 2. Management's Discussion & Analysis of Financial Condition & Results of Operations

This Form 10-Q, contains forward-looking statements. In some cases you can identify forward- looking statements by terminology such as "believe," "expect," "intend," "anticipate," "estimate," "predict," "potential," "propose" or "continue," variations of such words and similar expressions identifying forward looking statements. These statements are only predictions. Actual events or results may differ materially. In evaluating these statements, you should specifically consider various factors described below in the section entitled "Important Factors That May Affect Results."

Although we believe the expectations reflected in the forward-looking statements are reasonable, we cannot guarantee future results, levels of activity, performance or achievements. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this report. This report should be read in conjunction with the Company's Annual Report on Form 10-K filed with the U.S. Securities and Exchange Commission (SEC). The Company undertakes no obligation to update publicly any forward-looking statements to reflect new information, events or circumstances after the date of this report, or to reflect the occurrence of unanticipated events.

Critical Accounting Policies and Estimates

The "Management's Discussion and Analysis of Financial Condition and Results of Operations", as well as disclosures included elsewhere in this Form 10-Q, are based upon our financial statements, which have been prepared in accordance with accounting principles generally accepted in the United States of America. The preparation of these financial statements requires us to make estimates and judgments that affect the reported amounts of assets, liabilities, revenues and expenses, and related disclosure of contingencies. On an ongoing basis, we evaluate the estimates used, including those related to impairment and useful lives of intangible assets, allowances for accounts receivable and for excess and obsolete inventory. We base our estimates on historical experience, current conditions and on various other assumptions that are believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying values of assets and liabilities that are not readily apparent from other sources, as well as identifying and assessing our accounting treatment with respect to commitments and contingencies. Actual results may differ from these estimates under different assumptions or conditions. We believe the following critical accounting policies involve the more significant judgments and estimates used in the preparation of the consolidated financial statements.

Product revenues are recognized when products are shipped, license fees are recognized over the term of the license agreement, and royalties are recognized when earned. On occasion, the Company will receive advance deposits with customer purchase orders. These deposits are reported as a deferred revenue liability, until the product is shipped to the customer.

Approximately 21% of ProCyte's assets as of June 30, 2002 consist of intangible assets, most of which were acquired in business combinations and were recorded based on the fair value of the common stock we issued to effect those business combinations. Under the guidance of SFAS 142 "Goodwill and Other Intangible Assets" we analyze whether the fair value of recorded goodwill is impaired on an annual basis. Our analysis of whether the fair value of recorded goodwill is impaired involved a substantial amount of judgment, as does establishing and monitoring estimated lives of amortizable intangible assets. Future charges related to intangible assets could be material depending on future developments and changes in technology and our business.

We maintain an allowance for doubtful accounts for estimated losses resulting from the potential inability of our customers to make required payments. We believe such allowances are adequate as of June 30, 2002; however, if the financial condition of our customers or other debtors were to deteriorate, resulting in an impairment of their ability to make payments to us, additional allowances may be required.

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In valuating inventory, we consider excess and obsolete inventory. Some of our products carry a shelf life date. Products can potentially lose their saleable value if they are not sold several months before this shelf life date. However, there can be no guarantee that ProCyte can continue to sell products at its current rate. The value of ProCyte's inventory may decrease in the event that sales were to decrease.

Corporate Overview

ProCyte continues to follow its mission of expanding the use and consumer acceptance of GHK and AHK Copper Peptide technologies. During 2001, several new products were introduced in the Neova® Therapy line, including Neova® Antioxidant Therapy. The sunscreen product line was expanded with the introduction of Ti-Silc® Untinted Sunscreen and an improved formulation of Z-Silc™ Sunscreen. There were select additions and discontinuations in the regular product line to improve the product portfolio.

During 2001, ProCyte continued to develop and market its skin health and hair care products, and continued to work with its licensees to promote sales of Copper Peptide products. As the Company's product line has expanded, it has continued to focus its direct sales efforts on specialty skin health and wound care sectors, marketing its products primarily to dermatologists, plastic surgeons and cosmetic surgeons.

The GraftCyte® line of Copper Peptide containing wound care products are used following hair restoration surgery. ProCyte is the only company to provide a comprehensive line of products that address the importance of wound repair in the hair transplant procedure. The Company's GraftCyte® products are promoted through its own sales force and specialty distributors.

The Company has also continued to emphasize its Complex Cu₃® Intensive Repair Creme, Lotion, Cleanser and Hydrating Gel products to treat patients following chemical peels, microdermabrasion and laser treatments. The Complex Cu₃® System allows the Company to differentiate its line of skin care products on the basis of its proprietary Copper Peptide technology.

The Company markets its Tricomin® line of Triamino Copper Complex™ containing hair care products primarily to physicians and directly to consumers through its web site at www.tricomin.com. Tricomin® shampoos, conditioners, and follicle therapy solution are positioned to participate in the rapidly growing $1.5 billion worldwide hair care market as a program for the maintenance of thinning hair for both men and women. Hair follicles require high concentrations of biological copper, and the Tricomin® products deliver copper along with amino acids for nourishing and stimulating the hair and scalp for improved health, strength and appearance.

In 2001, substantial efforts were made with our various partners in gaining registrations and supplying the Copper Peptide technology. During the first quarter of 2001, the Company shipped significant quantities of Copper Peptide to Neutrogena for their launch in April 2001. Neutrogena has continued to expand its product offerings in 2002 and recently launched its first products in Europe. Additionally, the Company signed new consumer license agreements with American Crew, Creative Nail and Atelier Esthetique in 2001. The AHK Copper Peptide compound was licensed to American Crew for hair care in the salon market. The GHK Copper Peptide compound was licensed to Creative Nail Design for nail and hand care in the salon and spa market. All of these companies have launched products into their respective markets during the first half of 2002. ProCyte supplies finished skin care products to Atelier Esthetique for the U.S. salon and spa market. Merck experienced difficulties in selling the Iamin® Gel in Brazil. Its management in Latin America changed during 2001, and the new management has indicated a desire to discontinue sales of the Iamin® Gel. The Merck agreement was terminated on March 25, 2002.

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Amuchina, our partner in Europe, was acquired by Angelini ACRAF SpA Pharmaceutical. The change caused a significant slowdown in the registration process and product launch plans. They expect to initiate sales in late 2002.

Net Income (Losses)

ProCyte has reported net income for the second quarter of 2002 and for the first six months of the year. Net income for the quarter was $534,670 as compared to a net loss of $364,641 in the same quarter in 2001. Through the first six months of 2002, the Company reported net income of $1,023,546 as compared to a net loss of $866,306 reported for the same period last year. From ProCyte's inception through December 31, 2001, the Company's revenues were exceeded by the costs associated with researching and developing its proprietary technology and selling and marketing its products. Last year marked significant milestones in product sales growth, launching of strategic licensing agreements and eliminating the loss-generating contract manufacturing operation. At June 30, 2002, the Company's accumulated deficit was approximately $74.1 million.

Revenues

The Company's overall revenues for the quarter increased 35% to $3.3 million from $2.4 million reported in the year-earlier period. Revenues for the first six months were up 27% to $6.3 million as compared to $5.0 million reported for the same period in 2001. In July of 2001, the Company sold its contract manufacturing operations to Emerald Pharmaceutical L.P. Revenues, excluding contract manufacturing, were up 41% and 32% for the quarter and six month periods ended June 30, 2002, as compared to the same periods in the prior year.

For the second quarter, product sales were up 39% to $2,915,245, an $817,502 increase over $2,097,743 reported for the same quarter in 2001. Product sales of $5,668,645, reported for the first six months, were $1,254,341 or 28% higher than $4,414,304 reported in the year-earlier period. Sales to physicians and distributors were up 29% and 28% for the three months and six months periods as compared to the same periods in 2001. GHK and AHK Copper Peptide sales to ProCyte's licensing partners were also up 83% in the second quarter and 30% for six months. In the first six months of 2002, the Company launched a new line of products under the NextDerm™ brand name. These products are available to selected consumer markets through physicians. In the second quarter 2002, the Company continues to ship initial orders to Atelier Esthetique for its launch of Simple Solutions™ products into the salon and spa market. During 2002, the Company also shipped AHK Copper Peptide to American Crew for its Revitalize™ products, which were launched in the first quarter of this year. During the first six months of 2002, we continued to supply GHK Copper Peptide to Neutrogena for its Visibly Firm™ Active Copper™ products, which were initially launched in the first half of 2001.

ProCyte's second quarter royalty revenue increased 64% to $347,949, an increase of $135,603 over $212,346 reported for the same period in 2001. Royalties for the six months were up 84% to $636,949, a $290,438 increase as compared to the same prior-year period. The Company earns royalties on products sold by Neutrogena, American Crew and Creative Nail, which contain its patented copper peptide compounds.

Interest income for the second quarter increased to $46,166 as compared to $20,082 earned in the second quarter of 2001. For the six months, interest and other income increased to $92,963 as compared to $57,997 reported for the same period in 2001. Interest earnings for the second quarter and for the six months include $26,891 and $51,647, respectively, which was paid by Emerald Pharmaceutical L.P. on a $2,000,000 promissory note. During the first six months of 2002, the Company experienced lower market yields on its cash reserves as compared to the first six months in 2001.

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Expenses

In the second quarter of 2002, gross profit increased 32% to $2,166,692 (66% gross profit margin) as compared to $1,647,420 (68%) reported for the same quarter in 2001. Gross profit for the six months was also up 42% to $4,283,011 (68%) as compared to $3,009,609 (61%) reported for the year-earlier period. Gross profit margins will fluctuate from quarter to quarter based on product mix and licensee purchases of Copper Peptide for their products.

Total operating expenses were down 17% in the second quarter of 2002 to $1,678,188 from $2,032,143 reported for the second quarter in 2001. For the six months ended June 30, 2002 expenses were down 15% to $3,352,428 as compared to $3,933,912 reported for the same period in 2001. Marketing and selling expenses were down 14% for the second quarter of 2002 and 13% for the first six months of 2002 as the Company launched fewer new products as compared to the same period in 2001. General and administrative expenses also decreased 12% in both the second quarter and the first six months of 2002 as compared to the same periods in the prior year, due to the elimination of the contract manufacturing operations.

Liquidity and Capital Resources

The Company has relied primarily on equity financing, product sales, royalties and license fees, interest income and corporate partnerships to fund its operations and capital expenditures. At June 30, 2002, the Company had approximately $3.9 million in cash and cash equivalents, compared to $3.0 million at December 31, 2001. The net change in cash and cash equivalents during the six months ended June 30, 2002 reflects a net cash flow of $799,981 from operating activities. We expect to see fluctuations in accounts receivable, inventory, accounts payable and deferred revenues over the next several quarters as our strategic partners continue to initiate product introductions.

ProCyte did not own any derivative financial instruments as of June 30, 2002. The Company is debt-free and is exposed to interest rate risk only to the extent that it has invested idle cash balances. At June 30, 2002, such balances were invested in a United States Treasury money market fund. ProCyte employs established policies and procedures to manage its exposure to changes in the market risk of its investments. The Company believes that the market risk arising from holdings of its investment is not material. We hold a $2 million promissory note as a result of the sale of our contract manufacturing operation to Emerald Pharmaceutical LP. The note is guaranteed only by a security agreement, which gives ProCyte a first lien position on the assets sold to Emerald.

The Company believes that its existing cash and cash equivalents and interest thereon, will be sufficient to meet its working capital requirements for at least the next twelve months. However, there can be no assurance that the underlying assumed levels of revenue and expense will prove accurate. The Company will depend on product revenues, royalties and license fees, asset redeployment, interest income, equity financing, and funding from corporate partnerships to meet its future capital needs. See "Additional Factors That May Affect Results—Need for Additional Capital".

Additional Factors That May Affect Results

In addition to the other information contained in this report and our other reports filed with the SEC, the following factors could affect the Company's actual results and could cause our actual results to differ materially from those achieved in the past or expressed in our forwarding-looking statements.

History of Operating Losses; Accumulated Deficit; Fluctuations in Future Earnings

The Company has been launching products based on its proprietary Copper Peptide technology since mid-1996. It expects to continue to launch new Copper Peptide based products in the future. To date, the Company has generated increasing revenues from sales of products based on its proprietary

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technology and licensing agreements, but there can be no assurance that the Company can continue to generate sufficient revenues to sustain a profitable level of operations. As of June 30, 2002, the Company's accumulated deficit was approximately $74.1 million. In addition to sales of products based on its proprietary Copper Peptide technology, the Company's revenues have historically included sales of non-proprietary products, license fees and royalties, revenue from contract services and interest income. We sold our contract manufacturing operation in July 2001. There can be no assurance that the Company can sustain a consistent and profitable level of operations. Sustained profitability is dependent a wide variety of factors, including the Company's ability to successfully manufacture and market its products, enter into agreements with corporate partners for commercialization of the Company's products, and license the Company's products and technology. Payments under corporate partnerships and licensing arrangements, if any, may be subject to fluctuations in both timing and amounts. Moreover, the Company's level of profitability, if any, cannot be predicted and may vary significantly from quarter to quarter.

Need for Additional Capital

In the first half of 2002, the Company, for the first time since its inception, has generated net income from operations. The Company may require additional funds to sustain, expand or enhance its sales and marketing activities, continue product development, acquire a product line or company, or fund an infomercial. The Company's future capital requirements will depend on numerous factors, including: its efforts, and the efforts of its collaborative partners, to commercialize its products; the continued progress in the Company's research and development programs; the relationships with existing and future corporate collaborators, if any; the competing technological and market developments; the costs involved in filing, prosecuting and enforcing patent claims; the time and costs of commercialization activities. As of June 30, 2002, the Company had cash and cash equivalents of $3.9 million. The Company estimates that, at its planned rate of spending, its existing cash and cash equivalents and the interest income thereon will be sufficient to meet its capital requirements for at least the next twelve months. There can be no assurance that the underlying assumed levels of revenue and expense will prove accurate. Whether or not these assumptions prove to be accurate, the Company may need to raise additional capital. The Company may be required to seek additional funding through public or private financing, including equity financing, or through collaborative arrangements. Adequate funds for these purposes, whether obtained through financial markets or from collaborative or other arrangements with corporate partners or other sources, may not be available when needed or may not be available on terms favorable to the Company. If issuing equity securities raises additional funds, dilution to existing shareholders will result. In addition, in the event that additional funds are obtained through arrangements with collaborative partners, such arrangements may require the Company to relinquish its rights to certain technologies or potential products that it would otherwise seek to develop or commercialize on its own. If funding is insufficient at any time in the future, the Company may be required to: delay, scale back or eliminate some or all of its marketing and research and development programs; sell assets; or license to third parties the rights to commercialize products or technologies that the Company would otherwise seek to develop on its own. Furthermore, the terms of any such license agreements or asset sales might be less favorable than if the Company were negotiating from a stronger position.

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Uncertainties Related to Product Commercialization and Development

From its inception in 1986, until it launched its first commercial product in 1996, the Company has dedicated substantially all of its resources to the research and development of wound healing, hair growth and other therapeutic pharmaceutical applications of its Copper Peptide compounds. To date, the Company has generated increasing revenue from the sales of products based on its proprietary Copper Peptide technology. There can be no assurance that the Company's current products or future products, will be successfully commercialized and accepted for use by physicians, healthcare providers and consumers on a long-term basis.

Dependence on and Management of Existing and Future Corporate Alliances

The successful commercialization of the Company's existing and future products in the consumer markets and wound care markets will depend upon ProCyte's ability to enter into and effectively manage corporate partnerships. There can be no assurance that the Company will be successful in establishing corporate alliances in the future, or that it will be successful in maintaining existing or any future corporate alliances. Moreover, there can be no assurance that the interests and motivations of any corporate partner, distributor or licensee would be or remain consistent with those of the Company, or that such partners, distributors or licensees would successfully perform the necessary technology transfer, clinical development, regulatory compliance, manufacturing, marketing or other obligations. There can be no assurance that any of the Company's existing or future collaborators will perform their obligations under their agreements with the Company or that the Company's products or the products of others that incorporate the Company's products or technology will be successfully commercialized. Any of these factors could have a material adverse effect on the Company's business, financial condition and results of operations.

Uncertainty of Patent Position and Proprietary Rights

The patent positions of biotechnology, medical device and healthcare products companies are often uncertain and involve complex legal and factual questions, and the breadth of claims allowed in such patents cannot be predicted. In addition, there is a substantial backlog of patents at the US Patent and Trademark Office that may delay the review and the potential issuance of patents. The Company's success will depend significantly on its ability to obtain patents and licenses to patent rights, to maintain trade secrets, and to operate without infringing on the proprietary rights of others, both in the United States and in other countries. The failure of the Company or its licensors to obtain and maintain patent protection for the Company's technology could have a material adverse effect on the Company.

ProCyte's success depends, in part, upon its ability to protect its products and technology under intellectual property laws in the United States and abroad. As of June 30, 2002, the Company had 21 issued US patents expiring between 2005 and 2017 and numerous issued foreign patents and patent registrations. The patents relate to use of the Company's copper-based technology for a variety of healthcare applications, and to the composition of certain biologically active, synthesized compounds. The Company's strategy has been to apply for patent protection for certain compounds and their discovered uses that are believed to have potential commercial value in countries that offer significant market potential. There can be no assurance that patent applications relating to the technology used by the Company will result in patents being issued. There can be no assurance that any patent issued to the Company will not be subjected to further proceedings limiting the scope of the rights under the patent or that such patent will provide a competitive advantage, will afford protection against competitors with similar technology, or will not be successfully challenged, invalidated or circumvented by competitors.

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The Company's processes and potential products may conflict with patents that have been or may be granted to competitors and others. As the biotechnology, medical device and healthcare industries expand and more patents are issued, the risk increases that the Company's processes and potential products may give rise to claims that they infringe the patents of others. Such other persons could bring legal actions against the Company claiming damages and seeking to enjoin clinical testing, manufacturing and marketing of the affected product or use of the affected process. Litigation may be necessary to enforce patents issued to the Company, to protect trade secrets or know-how owned by the Company or to determine the enforceability, scope and validity of proprietary rights of others. If the Company becomes involved in such litigation, it could result in substantial expense to the Company and significant diversion of effort by the Company's technical and management personnel. In addition to any potential liability for significant damages, the Company could be required to obtain a license to continue to manufacture or market the affected product or use the affected process. Costs associated with any licensing arrangement may be substantial and could include ongoing royalties. There can be no assurance that any license required under any such patent would be made available to the Company on acceptable terms, if at all. If such licenses could not be obtained on acceptable terms, the Company could be prevented from manufacturing and marketing existing or potential products. Accordingly, an adverse determination in such litigation could have a material adverse effect on the Company's business, financial condition and results of operations.

The Company also relies on non-patented proprietary technology. There can be no assurance that the Company can meaningfully protect its rights to such non-patented technology, that any obligation to maintain the confidentiality of such proprietary technology will not be breached by employees, consultants, collaborators or others or that others will not independently develop or acquire substantially equivalent technology. To the extent that corporate partners or consultants apply Company technological information independently developed by them or by others to Company projects or apply Company technology or know-how to other projects, disputes may arise as to the ownership of proprietary rights to such information.    Any failure to protect non-patented proprietary technology or any breach of obligations designed to protect such technology or development of equivalent technology may have a material adverse effect on the Company's business, financial condition and results of operations.

Uncertainty of Government Regulatory Requirements

The manufacturing and marketing of ProCyte's products are subject to extensive regulation in the United States by the federal government, principally by the FDA, and in other countries by similar health and regulatory authorities. The Federal Food, Drug and Cosmetic Act, and the regulations promulgated thereunder, and other federal and state statutes govern, among other things, the testing, manufacture, safety, labeling, storage, record-keeping, advertising and promotion of cosmetic products and medical devices. Product development and approval or clearance within the regulatory framework requires a number of years and involves the expenditure of substantial resources.

The Company's products and product candidates may be regulated by any of a number of divisions of the FDA. The process of obtaining and maintaining regulatory approvals for the manufacturing or marketing of the Company's existing and potential products is costly and time-consuming and is subject to unanticipated delays. Regulatory requirements ultimately imposed could also adversely affect the ability of the Company to clinically test, manufacture or market products.

In the United States, products that do not seek to make effectiveness claims based on human clinical evaluation may be subject to review and regulation under the FDA's cosmetic or 510(k) medical device guidelines. Similar guidelines exist for such products in other countries. Such products, which include wound care dressings and certain ointments and gels, must show safety and substantial equivalency with predicate products already cleared by the FDA to be marketed. There can be no assurance that such product applications submitted to the FDA or similar agencies in other countries will receive clearance

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to be marketed, or that the labeling claims sought will be approved, or that, if cleared, such products will be commercially successful or free from third party claims relating to the effectiveness or safety of such products.

In addition to obtaining approval or clearance from the FDA or foreign regulatory bodies to market a product, the prospective manufacturer's quality control and manufacturing procedures must conform to current good manufacturing practices ("cGMP") guidelines, or ISO 9000 standards, when appropriate. In complying with these regulations, which are subject to change at any time without notice to the Company, ProCyte must continue to expend time, effort and financial resources in production and quality control. In addition, ProCyte's contract manufacturers may be subject to the regulations of and inspections by other foreign, federal, state or local agencies. There can be no assurance that the Company's contract manufacturers' facilities or operations will meet or continue to meet all appropriate guidelines or to pass inspections by any government agency.

The Company also is or may become subject to various other federal, state, local and foreign laws, regulations and policies relating to, among other things, safe working conditions, good laboratory practices, and the use and disposal of hazardous or potentially hazardous substances used in connection with its research and development.

The Company's failure to comply with applicable regulatory requirements, including obtaining required regulatory approvals and consents, could have a material adverse effect on the Company's business, financial condition and results of operations.

Intense Competition

Competition in the wound care, skin health and hair care markets is intense. The Company's competitors include well-established pharmaceutical, cosmetic and healthcare companies such as Obagi, Senetek, Allergan and Nioxin. These competitors may have more financial and other resources, larger research and development staffs, and more experience and capabilities in researching, developing and testing products in clinical trials, in obtaining FDA and other regulatory approvals and in manufacturing, marketing and distribution than the Company. In addition, a number of smaller companies are developing or marketing competitive products. The Company's competitors may develop and commercialize products or obtain patent protection or other regulatory approvals for products more rapidly than the Company. In addition, competitive products may be manufactured and marketed more successfully than the Company's potential products. Such developments could render the Company's existing or potential products less competitive or obsolete and could have a material adverse effect on the Company's business, financial condition and results of operations.

Potential Volatility of Stock Price; Bulletin Board Listing

The market prices for securities of healthcare, medical dressings, pharmaceutical and biotechnology companies are subject to volatility, and the market has from time to time experienced significant fluctuations that are unrelated to the operations of the Company. ProCyte's market price has fluctuated over a wide range since the Company's initial public offering in 1989, and since March 25, 1999, the Company's common stock has traded on the NASD OTC bulletin board. Because real-time price information may not be easily available for bulletin board securities, an investor is likely to find it more difficult to dispose of, or to obtain accurate quotations on the market value of, the Company's securities than if they were listed on a national exchange. In addition, purchases and sales of the Company's securities may become subject to Rule 15g-9 of the Exchange Act, which imposes various sales practice requirements on broker-dealers, or to the "penny stock" rules, either of which would likely reduce the level of trading activity in the secondary market for the Company's securities and make selling the securities more difficult for an investor.

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Announcements concerning the Company or its competitors, including fluctuations in operating results, research and development program direction, results of clinical trials, addition or termination of corporate alliances, technology licenses, clearance or approval to market products, announcements of technological innovations or new products by the Company or its competitors, changes in government regulations, healthcare reform, developments in patent or other proprietary rights of the Company or its competitors, litigation concerning business operations or intellectual property, or public concern as to safety of products, as well as changes in general market conditions and mergers and acquisitions, may have a significant effect on the market price of ProCyte's common stock.

Item 3. Quantitative and Qualitative Disclosures about Market Risk

ProCyte did not own any derivative financial instruments as of June 30, 2002. The Company is debt-free and is exposed to interest rate risk only to the extent that it has invested idle cash balances. At June 30, 2002, such balances were invested in a United States Treasury money market fund. ProCyte employs established policies and procedures to manage its exposure to changes in the market risk of its investments. The Company believes that the market risk arising from holdings of its financial instruments is not material. The Company holds a $2 million promissory note as a result of the sale of its contract manufacturing operation, which is secured by the manufacturing assets sold, and there is no guaranty.

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Part II—Other Information

Item 1. Legal Proceedings

Not applicable.

Item 2. Changes in Securities and Use of Proceeds

Not applicable.

Item 3. Defaults Upon Senior Securities

Not applicable.

Item 4. Submission of Matters to a Vote of Security Holders

The annual meeting of the shareholders of the Company was held on May 21, 2002. Two matters were submitted to the shareholders for a vote: the election of directors and a proposal to increase the number of shares reserved for issuance under the Company's 1996 employee stock option plan. As of April 4, 2002, the record date, there were 15,695,833 shares eligible to vote at the meeting, of which, 90.66% or 14,229,819 were represented at the meeting, constituting a quorum.

The five nominees for election as directors were elected to serve until 2003 annual meeting of the shareholders, and until the election and qualification of their respective successors. The vote for each director follows:

The other proposal was approved by the shareholders. The vote was as follows:

Item 5. Other Information

Not applicable.

Item 6. Exhibits and Reports on Form 8-K

(a)

Exhibits

See Exhibit Index on page 23.

(b)

Reports on Form 8-K

None.

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Signatures

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

22

Exhibit Index

*

Management contract or compensatory plan or arrangement.

†

Confidential treatment has been granted or requested with respect to portions of this exhibit.

A.

Incorporated by reference to the Registrant's Registration Statement of Form S-1 (No. 33-31353).

B.

Incorporated by reference to the Registrant's Registration Statement of Form S-1 (No. 33-46364).

C.

Incorporated by reference to the Registrant's Annual Report on Form 10-K for the year ended December 31, 1994.

D.

Incorporated by reference to the Registrant's Annual Report on Form 10-K for the year ended December 31, 1996.

F.

Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the Quarter ended June 30, 1998.

G.

Incorporated by reference to the Registrant's Amended Annual Report on Form 10-K/A dated December 31, 1997.

H.

Incorporated by reference to the Registrant's Amended Annual Report on Form 10-K/A dated December 31, 1998.

I.

Incorporated by reference to the Registrant's Quarterly Report on Form 10-Q for the Quarter ended March 31, 2000.

J.

Submitted herewith

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QuickLinks

Item 1. Condensed Financial Statements (unaudited)

Item 2. Management's Discussion & Analysis of Financial Condition & Results of Operations

Item 3. Quantitative and Qualitative Disclosures about Market Risk

Item 1. Legal Proceedings
Item 2. Changes in Securities and Use of Proceeds
Item 3. Defaults Upon Senior Securities
Item 4. Submission of Matters to a Vote of Security Holders
Item 5. Other Information
Item 6. Exhibits and Reports on Form 8-K