SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2002 OR [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number 0-18311 NEUROGEN CORPORATION (Exact name of registrant as specified in its charter) Delaware 22-2845714 (State or other jurisdiction of (I.R.S. Employer incorporation or organization) Identification No.) 35 Northeast Industrial Road Branford, Connecticut 06405 (Address of principal executive offices) (Zip Code) (203) 488-8201 (Registrant's telephone number, including area code) Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes X No --- --- As of August 14, 2002 the registrant had 17,809,374 shares of Common Stock outstanding. NEUROGEN CORPORATION INDEX Part I - Financial Information Item 1. Consolidated Financial Statements Consolidated Balance Sheets at June 30, 2002 and December 31, 2001 Consolidated Statements of Operations for the three-month and six-month periods ended June 30, 2002 and 2001 Consolidated Statements of Cash Flows for the six-month periods ended June 30, 2002 and 2001 Notes to Consolidated Financial Statements Item 2. Management's Discussion and Analysis of Financial Condition and Results of Operations Item 3. Quantitative and Qualitative Disclosures About Market Risk Part II - Other Information Item 1. Legal Proceedings Item 2. Changes in Securities and Use of Proceeds Item 3. Defaults upon Senior Securities Item 4. Submission of Matters to a Vote of Security Holders Item 5. Other Information Item 6. Exhibits and Reports on Form 8-K Signature Exhibit Index PART I - FINANCIAL INFORMATION ITEM 1 - CONSOLIDATED FINANCIAL STATEMENTS NEUROGEN CORPORATION CONSOLIDATED BALANCE SHEETS (In thousands) (UNAUDITED) JUNE 30, 2002 DECEMBER 31, 2001 -------------- ----------------- Assets Current assets: Cash and cash equivalents $ 28,846 $ 51,062 Restricted cash 1,009 1,500 Marketable securities 60,796 54,237 Receivables from corporate partners 3,285 1,554 Other current assets 1,235 3,027 ------------- --------------- Total current assets 95,171 111,380 Property, plant & equipment: Land, building and improvements 31,176 30,489 Equipment and furniture 17,257 16,162 Construction in progress 142 462 --------------- ---------------- 48,575 47,113 Less accumulated depreciation & amortization 14,413 13,062 --------------- ---------------- Net property, plant and equipment 34,162 34,051 Other assets, net 656 525 --------------- ---------------- Total assets $ 129,989 $ 145,956 =============== ================ See accompanying notes to consolidated financial statements. NEUROGEN CORPORATION CONSOLIDATED BALANCE SHEETS (In thousands, except per share data) (UNAUDITED) JUNE 30, 2002 DECEMBER 31, 2001 ----------------- ----------------- Liabilities & Stockholders' Equity Current liabilities: Accounts payable and accrued expenses $ 4,746 $ 3,595 Unearned revenue from corporate partners, current portion 2,000 6,699 Current portion of loans payable 1,372 1,365 ----------------- ------------------ Total current liabilities 8,118 11,659 Unearned revenue from corporate partners, net of current portion 6,885 7,885 Loans payable, net of current portion 20,341 21,029 ----------------- ------------------ Total liabilities 35,344 40,573 Commitments and Contingencies Stockholders' Equity: Preferred stock, par value $.025 per share Authorized 2,000 shares; none issued - - Common stock, par value $.025 per share Authorized 30,000 shares; issued and outstanding 17,859 shares at June 30, 2002 and 17,733 shares at December 31, 2001 446 443 Additional paid-in capital 176,568 174,709 Accumulated deficit (79,108) (67,685) Deferred compensation (3,678) (2,750) Accumulated other comprehensive income 417 666 ----------------- ------------------ Total stockholders' equity 94,645 105,383 ----------------- ------------------ Total liabilities and stockholders' equity $ 129,989 $ 145,956 ================= ================== See accompanying notes to consolidated financial statements. NEUROGEN CORPORATION CONSOLIDATED STATEMENTS OF OPERATIONS (In thousands, except per share data) (UNAUDITED) THREE MONTHS THREE MONTHS SIX MONTHS SIX MONTHS ENDED ENDED ENDED ENDED JUNE 30, 2002 JUNE 30, 2001 JUNE 30, 2002 JUNE 30, 2001 ---------------- --------------- -------------- ------------- Operating revenues: License fees $ 7,061 $ 2,495 $ 8,449 $ 3,745 Research and development 1,209 720 2,459 1,440 ---------------- --------------- ------------- ------------- Total operating revenues 8,270 3,215 10,908 5,185 Operating expenses: Research and development: Stock compensation 38 18 (18) 902 Other research and development 9,836 8,659 19,272 17,286 ---------------- --------------- ------------- ------------- Total research and development 9,874 8,677 19,254 18,188 General and administrative: Stock compensation 151 27 290 72 Other general and administrative 1,660 1,442 3,706 3,289 ---------------- --------------- ------------- ------------- Total general and administrative 1,811 1,469 3,996 3,361 ---------------- --------------- ------------- ------------- Total operating expenses 11,685 10,146 23,250 21,549 ---------------- --------------- ------------- ------------- Operating loss (3,415) (6,931) (12,342) (16,364) Other income (expense): Investment income 811 1,242 1,547 2,751 Interest expense (274) - (554) - ---------------- --------------- ------------- ------------- Total other income, net 537 1,242 993 2,751 ---------------- --------------- ------------- ------------- Net loss before provision for income taxes (2,878) (5,689) (11,349) (13,613) Provision for income taxes - - (73) - ---------------- --------------- ------------- ------------- Net loss $ (2,878) $ (5,689) $ (11,422) $ (13,613) ================ =============== ============= ============= Basic and diluted loss per share $ (0.16) $ (0.33) $ (0.65) $ (0.78) ================ =============== ============= ============= Shares used in calculation of loss per share: Basic and diluted 17,607 17,416 17,600 17,406 ================ =============== ============= ============= See accompanying notes to consolidated financial statements. NEUROGEN CORPORATION CONSOLIDATED STATEMENTS OF CASH FLOWS (In thousands) (UNAUDITED) SIX MONTHS SIX MONTHS ENDED ENDED JUNE 30, 2002 JUNE 30, 2001 ----------------- --------------- Cash flows from operating activities: Net loss $ (11,422) $ (13,613) Adjustments to reconcile net loss to net cash used in operating activities: Depreciation and amortization expense 1,590 1,307 Stock compensation expense 272 974 Other non-cash expense 846 463 Changes in operating assets and liabilities: Increase (decrease) in accounts payable and accrued expenses 1,151 (897) Decrease in unearned revenue from corporate partners (5,699) (1,745) (Increase) decrease in receivables from corporate partners (1,732) 1,418 Decrease in other assets, net 1,598 733 Income tax benefits from exercise of stock options 345 - ----------------- --------------- Net cash used in operating activities (13,051) (11,360) Cash flows from investing activities: Purchases of plant and equipment (1,824) (5,081) Purchases of marketable securities (42,562) (42,526) Maturities and sales of marketable securities 35,309 34,087 Proceeds from sales of assets 102 25 ----------------- --------------- Net cash used in investing activities (8,975) (13,495) Cash flows from financing activities: Principal payments under loans payable (681) - Change in restricted cash 491 - Exercise of employee stock options - 564 ----------------- --------------- Net cash (used in) provided by financing activities (190) 564 ----------------- --------------- Net decrease in cash and cash equivalents (22,216) (24,291) Cash and cash equivalents at beginning of period 51,062 48,086 ----------------- --------------- Cash and cash equivalents at end of period $ 28,846 $ 23,795 ================= =============== See accompanying notes to consolidated financial statements. Neurogen Corporation Notes to Consolidated Financial Statements June 30, 2002 (Unaudited) (1) BASIS OF PRESENTATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES The unaudited consolidated financial statements have been prepared from the books and records of Neurogen Corporation ("Neurogen" or the "Company") in accordance with generally accepted accounting principles for interim financial information pursuant to Rule 10-01 of Regulation S-X. Accordingly, they do not include all of the information and footnotes required by generally accepted accounting principles in the United States of America for complete consolidated financial statements. In the opinion of management, all adjustments (consisting of normal recurring accruals) considered necessary for a fair presentation have been included. These interim consolidated financial statements should be read in conjunction with the audited consolidated financial statements for the year ended December 31, 2001 included in the Company's Annual Report on Form 10-K. Interim results are not necessarily indicative of the results that may be expected for the full fiscal year. Comprehensive loss for the six-month periods ending June 30, 2002 and 2001 were $11,671,000 and $13,454,000, respectively. The differences between net loss and comprehensive net loss is due to changes in the unrealized gain(loss) on marketable securities. (2) PRINCIPLES OF CONSOLIDATION The consolidated financial statements include the accounts of the parent company and a subsidiary, Neurogen Properties LLC, after elimination of intercompany transactions. (3) REVENUE RECOGNITION The Company has entered into collaborative research agreements which provide for the partial funding of specified projects in exchange for the grant of certain rights related to discoveries. Revenue under these arrangements typically includes upfront non-refundable fees, ongoing payments for specified levels of staffing for research and milestone payments upon the occurrence of certain events. Since the adoption of the Securities and Exchange Commission's Staff Accounting Bulletin No. 101, the upfront fees are generally recognized as revenue ratably over the period of performance under the research agreement. The research funding is recognized as revenue as the related research effort is performed. Revenue derived from the achievement of milestones is recognized when the milestone event occurs. Neurogen has also entered into one technology transfer agreement under which revenue is recognized when a contractual arrangement exists, fees are fixed and determinable, delivery of the technology has occurred and collectibility is reasonably assured. When customer acceptance is required, revenue is deferred until acceptance occurs. Where there are on-going services or obligations after delivery, revenue is recognized over the related term of the service on a percentage of completion basis, unless such obligation is maintenance, which is recognized on a straight line basis. Generally, the agreement includes multiple elements and total contract fees are allocated to the different elements based on evidence of fair value. Revenue resulting from up-front non-refundable fees under collaborative research agreements and all fees under the technology transfer agreement is recorded as License Fees revenue for purposes of the financial statements. Research funding for the Company's staffing on projects and milestone payments under collaborative agreements are recorded as Research and Development revenues. Deferred revenue arises from the payments received for research and development to be conducted in future periods or for licenses of Neurogen's rights or technology where Neurogen has continuing involvement. (4) STOCK-BASED AWARDS In May 2002, an aggregate of 100,000 shares of restricted stock were granted to certain newly hired officers and one existing officer. Of the total shares granted, 50% vest after four years and 50% after five years from date of grant provided the officer remains an employee of the Company. In January 2002, 15,000 options to purchase common stock at the exercise price of $14.30 were granted to a director of the Company for consulting services to be performed. In the second quarter, the Company recorded deferred compensation totaling $1,380,000, which is being amortized ratably over the service period required for awards to vest. For the six months ending June 30, 2002, the Company recorded $44,000 in non-cash compensation expense related to 2002 awards. Item 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS Since its inception in September 1987, Neurogen has been engaged in the discovery and development of drugs. The Company has not derived any revenue from product sales and expects to incur significant losses in most years prior to deriving any such product revenues. Revenues to date have come from five collaborative research agreements, one license agreement and one technology transfer agreement. RESULTS OF OPERATIONS Results of operations may vary from period to period depending on numerous factors, including the timing of income earned under existing or future strategic alliances, technology transfer agreements, joint ventures or financings, if any, the progress of the Company's research and development and technology transfer projects, technological advances and determinations as to the commercial potential of proposed products. Neurogen expects research and development costs to increase significantly over the next several years as its drug development programs progress. In addition, general and administrative expenses necessary to support the expanded research and development activities are generally expected to increase for the foreseeable future. THREE MONTHS ENDED JUNE 30, 2002 AND 2001 The Company's operating revenues increased to $8.3 million for the three months ended June 30, 2002 as compared to $3.2 million for the same period in 2001. This increase is primarily due to the recognition of $4.2 million in revenue deferred until the June 2002 completion of a technology transfer agreement with Pfizer Inc ("Pfizer"), described below, and the $2.0 million recognition of revenues under such agreement for the achievement of a milestone event. License fee revenue in 2002 also includes the recognition of $0.5 million of a total up-front payment of $10.0 million received as part of our collaboration with Aventis Pharmaceuticals Inc. ("Aventis") in December 2001 (the "Aventis Agreement"), which is described below. Research and development revenue recognized in 2002 relates to research funding earned from the Aventis Agreement, whereas the revenue for 2001 represents the recognition of discovery research funding under a collaboration with Pfizer which concluded on December 31, 2001. Research and development expenses increased 14 percent to $9.8 million for the three-month period ended June 30, 2002 as compared to $8.7 million for the same period in 2001 excluding non-cash stock compensation charges. The increase is primarily due to further development of potential drug candidates, including the funding of clinical trials for the Company's candidate for the treatment of certain inflammatory disorders, the Company's continued utilization of its AIDD (Accelerated Intelligent Drug Design) Program for the discovery of new drug candidates and an increase in research and development personnel. Research and development expenses represented 86 percent of total expenses in each of the three month periods ended June 30, 2002 and 2001, excluding non-cash stock compensation charges. General and administrative expenses, excluding non-cash stock compensation charges, increased 15 percent to $1.7 million for the three-month period ended June 30, 2002 compared to $1.4 million for the same period in 2001. The increase is a result of additional business operations and technical services required to facilitate Neurogen's continued drug discovery and drug development activity, as well as to expand the Company's intellectual property estate. Other income decreased from $1.2 million in the three-month period ended June 30, 2001 to $0.5 million in the same period of 2002. This difference is primarily due to an increase in interest expense associated with a $17.5 million first mortgage debt financing the Company entered into in December 2001 and to lower overall returns on invested funds. The Company recognized a net loss of $2.9 million for the three months ended June 30, 2002 as compared with a net loss of $5.7 million for the same period in 2001. The decrease in net loss is primarily due to the increase in revenues partly offset by the increase in operating expenses and decrease in other income described above. SIX MONTHS ENDED JUNE 30, 2002 AND 2001 The Company's operating revenues increased to $10.9 million for the six months ended June 30, 2002 from $5.2 million for the same period in 2001. This increase is primarily due to the recognition of $4.2 million in revenue deferred until the June 2002 completion of a technology transfer agreement with Pfizer, described below, and the $2.0 million recognition of revenues under such agreement for the achievement of a milestone event. License fee revenue in 2002 also includes the recognition of $1.0 million of a total up-front payment of $10.0 million received as part of the Aventis Agreement, which is described below. Research and development revenue recognized in 2002 relates to research funding earned from the Aventis Agreement, whereas the revenue for 2001 represents the recognition of discovery research funding under a collaboration with Pfizer which concluded on December 31, 2001. Research and development expenses, excluding non-cash stock compensation charges, increased 11 percent to $19.3 million for the six-month period ended June 30, 2002 as compared to $17.3 million for the same period in 2001. The increase is primarily due to further development of potential drug candidates, including the funding of clinical trials for the Company's candidate for the treatment of certain inflammatory disorders, the Company's continued utilization of its AIDD Program for the discovery of new drug candidates and an increase in research and development personnel. Research and development expenses represented 84 percent of total operating expenses (excluding non-cash stock compensation charges)in each of the six-month periods ended June 30, 2002 and 2001. General and administrative expenses, excluding non-cash stock compensation charges, increased 13 percent to $3.7 million for the six-month period ended June 30, 2002 compared to $3.3 million for the same period in 2001. The increase is a result of additional business operations and technical services required to facilitate Neurogen's continued drug discovery and drug development activity, as well as to expand the Company's intellectual property estate. Total stock compensation expenses decreased from $1.0 million for the six-month period ended June 30, 2001 to $0.3 million for the same period in 2002. The 2002 compensation expense is composed of continuing non-cash charges to income related to grants of certain stock awards in 1997, 2001 and 2002 to certain officers of the Company, while the 2001 expense included a one-time non-cash charge of $0.8 million for the modification of certain stock options held by a retiring executive officer. Other income decreased from $2.8 million in the six-month period ended June 30, 2001 to $1.0 million in the same period of 2002. This difference is primarily due to an increase in interest expense associated with a $17.5 million first morgage debt financing the Company entered into in December 2001 and to lower overall returns on invested funds. The Company recognized a net loss of $11.4 million for the six months ended June 30, 2002 as compared with a net loss of $13.6 million for the same period in 2001. The decrease in net loss is primarily due to the increase in revenues partly offset by the increase in operating expenses and decrease in other income descibed above. LIQUIDITY AND CAPITAL RESOURCES At June 30, 2002 and December 31, 2001, cash, cash equivalents (including restricted cash) and marketable securities were in the aggregate $90.7 million and $106.8 million , respectively. A total amount of $27.2 million of the marketable securities at June 30, 2002 have maturities greater than one year. However, the Company can and may liquidate such investments prior to maturity to meet its strategies and/or investment objectives. The Company's aggregate level of cash, cash equivalents and marketable securities decreased during the first half of 2002. These levels have fluctuated significantly in the past and are expected to do so in the future as a result of the factors described below. Neurogen's cash requirements to date have been met by the proceeds of its equity financing activities, amounts received pursuant to collaborative research, licensing or technology transfer arrangements, certain debt arrangements and interest earned on invested funds. The Company's equity financing activities have included underwritten public offerings of common stock, private placement offerings of common stock and private sales of common stock in connection with collaborative research and licensing agreements. Total funding received from these financing activities was approximately $146.6 million. The Company's expenditures have been primarily to fund research and development and general and administrative expenses and to construct and equip its research and development facilities. The debt agreements entered into by the Company to date include a first mortgage loan financing in December 2001, and a construction loan entered into in October 1999. Total proceeds received under these agreements was $22.5 million. As of June 30, 2002, Neurogen is not engaged in any significant lease or capital expenditure commitments. The Company plans to use its cash, cash equivalents and marketable securities for its research and development activities, working capital and general corporate purposes. Neurogen anticipates that its current cash balance, as supplemented by research funding pursuant to its collaborative research, licensing and technology transfer agreements, will be sufficient to fund its current and planned operations through at least 2004. However, Neurogen's funding requirements may change and will depend upon numerous factors, including but not limited to, the progress of the Company's research and development programs, the timing and results of preclinical testing and clinical studies, the timing of regulatory approvals, technological advances, determinations as to the commercial potential of its proposed products, the status of competitive products and the ability of the Company to establish and maintain collaborative arrangements with others for the purpose of funding certain research and development programs, conducting clinical studies, obtaining regulatory approvals and, if such approvals are obtained, manufacturing and marketing products. Many of these factors could significantly increase the Company's expenses and use of cash. The Company anticipates that it may augment its cash balance through financing transactions, including the issuance of debt or equity securities and further corporate alliances. No assurances can be given that adequate levels of additional funding can be obtained on favorable terms, if at all. As of December 31, 2001, the Company had approximately $83.6 million and $6.1 million of net operating loss and research and development credit carryfowards, respectively, available for federal income tax purposes which expire in the years 2004 through 2021. The Company also had approximately $73.3 million and $3.5 million of Connecticut state tax net operating loss and research and development credit carryfowards, respectively, which expire in the years 2002 through 2021. The Company applied to exchange year 2000 Connecticut research and development credits for cash proceeds under new Connecticut tax law provisions and received a payment from the State of Connecticut of $2.2 million in April 2002 for this exchange. Because of "change in ownership" provisions of the Tax Reform Act of 1986, the Company's utilization of its net operating loss and research and development credit carryforwards may be subject to an annual limitation in future periods. COLLABORATIVE RESEARCH AGREEMENTS Aventis ------- In December 2001, Neurogen entered into a collaboration and license agreement with Aventis pursuant to which Aventis made an initial payment of $10 million and agreed, among other things, to fund a specified level of resources for at least three years for Neurogen's program for the discovery and research of CRF1 receptor-based drugs for a broad range of applications, including the therapeutic treatment of depression and anxiety disorders. Aventis has the option to extend the discovery and research effort for up to an additional two years. As of June 30, 2002, Aventis has provided $1.5 million of research funding to the Company. Neurogen is also eligible to receive milestone payments if certain compound discovery, product development or regulatory objectives are achieved subject to the collaboration. In return, Aventis received the exclusive worldwide rights to develop, manufacture and market collaboration drugs that act through the CRF1 receptor, for all therapeutic indications for which the drugs may be used. Aventis will pay Neurogen royalties based upon net sales levels, if any, for collaboration products. Also under the agreement, Aventis is responsible for funding the cost of development, including clinical trials, manufacturing and marketing of collaboration products, if any. Pfizer ------ In June 1999, Neurogen and Pfizer entered into a technology transfer agreement (the "Pfizer Technology Transfer Agreement"). Under the terms of this agreement, Pfizer agreed to pay Neurogen a total of up to $27.0 million over a three year period for the licensing and transfer to Pfizer of certain of Neurogen's AIDD technologies for the discovery of new drugs, along with the installation of an AIDD system. Additional payments are also possible upon Pfizer's successful utilization of this technology. Pfizer received a non-exclusive license to certain AIDD intellectual property and the right to employ this technology in its own drug development programs. As of June 30, 2002, Pfizer had provided $25.0 million in license fees pursuant to the Pfizer Technology Transfer Agreement, which culminated in June 2002. ITEM 3. QUANTITATIVE AND QUALITATIVE DISCLOSURES ABOUT MARKET RISK Interest rate risk. The Company's investment portfolio includes investment grade debt instruments. These securities are subject to interest rate risk, and could decline in value if interest rates fluctuate. Due to the short duration and conservative nature of these instruments, the Company does not believe that it has a material exposure to interest rate risk. Additionally, funds available from investment activities are dependent upon available investment rates. These funds may be higher or lower than anticipated due to interest rate volatility. Capital market risk. The Company currently has no product revenues and is dependent on funds raised through other sources. One source of funding is through further equity offerings. The ability of the Company to raise funds in this manner is dependent upon capital market forces affecting the stock price of the Company. Part II - Other Information Item 1. Legal Proceedings Not applicable for the second quarter ended June 30, 2002. Item 2. Changes in Securities and Use of Proceeds Not applicable for the second quarter ended June 30, 2002. Item 3. Defaults upon Senior Securities Not applicable for the second quarter ended June 30, 2002. Item 4. Submission of Matters to a Vote of Security Holders Not applicable for the second quarter ended June 30, 2002. Item 5. Other Information Certifications pursuant to Section 906 of the Sarbanes-Oxley Act of 2002 accompany this report. Item 6. Exhibits and Reports on Form 8-K (a) See Exhibit Index. (b) None. SAFE HARBOR STATEMENT Statements which are not historical facts, including statements about the Company's confidence and strategies, the status of various product development programs, the sufficiency of cash to fund planned operations and the Company's expectations concerning its development compounds, drug discovery technologies and opportunities in the pharmaceutical marketplace are "forward looking statements" within the meaning of the Private Securities Litigations Reform Act of 1995 that involve risks and uncertainties and are not guarantees of future performance. These risks include, but are not limited to, difficulties or delays in development, testing, regulatory approval, production and marketing of any of the Company's drug candidates, the failure to attract or retain scientific management personnel, any unexpected adverse side effects or inadequate therapeutic efficacy of the Company's drug candidates which could slow or prevent product development efforts, competition within the Company's anticipated product markets, the Company's dependence on corporate partners with respect to research and development funding, regulatory filings and manufacturing and marketing expertise, the uncertainty of product development in the pharmaceutical industry, inability to obtain sufficient funds through future collaborative arrangements, equity or debt financings or other sources to continue the operation of the Company's business, risk that patents and confidentiality agreements will not adequately protect the Company's intellectual property or trade secrets, dependence upon third parties for the manufacture of potential products, inexperience in manufacturing and lack of internal manufacturing capabilities, dependence on third parties to market potential products, lack of sales and marketing capabilities, potential unavailability or inadequacy of medical insurance or other third-party reimbursement for the cost of purchases of the Company's products, and other risks detailed in the Company's Securities and Exchange Commission filings, including its Annual Report on Form 10-K for the year ended December 31, 2001, each of which could adversely affect the Company's business and the accuracy of the forward-looking statements contained herein. SIGNATURE Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized. NEUROGEN CORPORATION By:/s/ STEPHEN R. DAVIS ------------------------ Stephen R. Davis Executive Vice President and Chief Business Officer Date: August 14, 2002 EXHIBIT INDEX Exhibit - ------- Number - ------ 10.1 - Employment Agreement between the Company and Edmund P. Harrigan, dated as of May 13, 2002. 10.2 - Form of Proprietary Information and Inventions Agreement. EXHIBIT 10.1 EMPLOYMENT AGREEMENT This EMPLOYMENT AGREEMENT, effective as of May 13, 2002, is made by and between Neurogen Corporation, a Delaware corporation (the "Company"), with offices at 35 Northeast Industrial Road, Branford, Connecticut 06405, and Edmund P. Harrigan, M.D. (the "Employee"). WHEREAS, the Company and the Employee desire to enter into an employment relationship; and WHEREAS, the Company and the Employee desire to enter into this Agreement to address, on the terms and conditions hereinafter set forth, certain matters relating to such employment. NOW, THEREFORE, the Company and the Employee agree as follows: 1. DEFINITIONS (a) Cause For purposes of this Agreement "cause" means: (i) the Employee is convicted of a felony or entry of a plea of nolo contendere (or similar plea) in a criminal proceeding for commission of a felony or serious misdemeanor; (ii) any willful act or omission by the Employee which constitutes gross misconduct or gross negligence and which results in demonstrable material harm to the Company; (iii) the Employee's willful and continuous failure to perform his duties with the Company after reasonable notice of such failure; (iv) the Employee's participation in any act of dishonesty intended to result in his material personal enrichment at the expense of the Company; or (v) the Employee's failure to substantially comply with the terms set forth in the Proprietary Information and Inventions Agreement between the Employee and the Company. No act, or failure to act, by the Employee shall be considered "willful" unless committed in bad faith and without a reasonable belief that the act or omission was in the Company's best interest. (b) Good Reason For purposes of this Agreement "good reason" means and shall be deemed to exist if, without the prior written consent of the Employee, (i) the Company permanently relocates the primary place of performance of the duties specified in Section 3 of this Agreement to a location more than fifty (50) miles from its current offices located in Branford, Connecticut; (ii) the Employee suffers a material reduction in Employee's duties, responsibilities or effective authority as a result of any action or inaction on the part of the Company typically associated with his title and position as set forth and described in Section 3 of this Agreement; (iii) the Employee's rate of Base Salary (as hereinafter defined) is materially decreased by the Company (other than in connection with an across the board salary reduction agreed to by the Employee); (iv) the Company fails to obtain the full assumption of this Agreement by a successor entity in accordance with Section 12(b) of this Agreement; or (v) the Board of Directors of the Company (the "Board") or the Company's stockholders, either or both, as may be required to authorize the same, shall approve any liquidation or dissolution of the Company, or the sale of all or substantially all of the assets of the Company. 2. TERM The term of Employee's employment under this Agreement shall, unless earlier terminated under Section 7 herein or extended as hereinafter provided, be for a period commencing as of May 13, 2002 (the "Commencement Date") and terminating on May 12, 2004, subject to the terms and conditions contained in this Agreement (the "Employment Period"). The Employment Period shall automatically be extended, commencing on May 13, 2004 and thereafter on the relevant alternate anniversary of the Commencement Date, for successive two (2) year periods unless, not later than ninety (90) days prior to May 13, 2004 or any such anniversary, either party to this Agreement shall give written notice to the other that such party does not wish to extend or further extend the Employment Period beyond its then already automatically extended term, if any. 3. DUTIES AND SERVICES During the Employment Period, the Employee shall be employed as Executive Vice President and Chief Development Officer of the Company. In such position, the Employee shall have the duties, responsibilities and authority normally associated with, or otherwise appropriate to, the offices and positions of an Executive Vice President and Chief Development Officer of a corporation. In the performance of his duties and responsibilities as Executive Vice President and Chief Development Officer, the Employee shall report only to the President and/or the Chief Executive Officer of the Company. During the Employment Period, the Employee shall devote substantially all of his business time, during normal business hours, to the business and affairs of the Company and the Employee shall use his best efforts to perform faithfully and efficiently the duties and responsibilities contemplated by this Agreement; provided, however, the Employee may manage his personal, financial and legal affairs and engage in any activities of a volunteer, civic or business nature, as long as such activities do not materially interfere with Employee's responsibilities as Executive Vice President and Chief Development Officer. 4. COMPENSATION AND OTHER BENEFITS (a) Salary As compensation for the Employee's services under this Agreement, beginning the Commencement Date and until the termination of the Employment Period, the Employee shall be paid by the Company a base salary of $300,000.00 per annum, payable in equal semi-monthly installments in accordance with the Company's normal payroll practices, which base salary may be increased but not decreased during the Employment Period by the Board in its sole discretion (the "Base Salary"). Such increased Base Salary shall then constitute the "Base Salary" for purposes of this Agreement. (b) Annual Bonus In addition to the Base Salary, the Employee is eligible to receive, subject to certain objective and/or subjective performance goals approved by the President and Chief Executive Officer, such annual bonuses during the Employment Period as the Board may approve. (c) Benefits During the Employment Period, the Employee shall be eligible to participate in all employee pension and incentive benefit plans and programs maintained from time to time by the Company for the benefit of senior executives. During the Employment Period, the Employee, Employee's spouse, if any, and their eligible dependents, if any, shall be eligible to participate in and be covered under all the employee and dependent health and welfare benefit plans or programs maintained from time to time by the Company. However, the Company shall have no obligations under this Section 4(c) unless and until the Employee has met any generally applicable eligibility requirements for participation in such plans and programs. (d) Loan As of the Commencement Date, the Company will loan to the Employee, interest free, $250,000 (the "Loan"). On each anniversary of the Commencement Date the Company will forgive $50,000 of the outstanding principal balance of the Loan, provided the Employee remains an employee of the Company on such anniversary date. Should the Employee's employment relationship with the Company terminate for any reason, any remaining principal balance of the loan shall be due and payable within thirty (30) days of such termination. While the Employee remains an employee of the Company, the Company will "gross up" and pay on behalf of the employee the actual federal and state income taxes owed by the Employee as a consequence of any interest which, due to the interest-free nature of the Loan, is required to be imputed in calculating the Employee's taxes. The Employee will be responsible for paying any taxes owed as a consequence of any principal amounts forgiven. (e) Equity As of the Commencement Date, the Company will grant to the Employee: (i) Forty thousand (40,000) shares of Neurogen Corporation restricted common stock, par value $.025 per share, (the "Restricted Stock"). The Restricted Stock shall vest and become unrestricted and freely tradable, subject to any governmental law, rule, regulation or order which would be applicable to the Employee generally (e.g. the Employee's knowledge of material non-public information regarding the Company) in two equal installments, twenty thousand (20,000) shares on May 13, 2006 and twenty thousand (20,000) shares on May 13, 2007. If for any reason the Employee's employment with the Company is terminated prior to either of the dates indicated in the preceding sentence, any unvested shares of Restricted Stock shall be forfeited to the Company for zero (0) consideration. (ii) An employee stock option (the "Stock Option") to acquire one hundred and twenty-five thousand (125,000) shares of Neurogen Corporation common stock at the then-current NASDAQ market price as of the date of grant. The Stock Option shall vest in five equal annual installments commencing on the first anniversary of the date of grant. 5. NON-COMPETITION (a) During the Employment Period and for one year after the date of any such termination of employment, the Employee agrees that, without the prior express written consent of the Company, he shall not, directly or indirectly, for his own benefit or as an employee, owner, shareholder, partner, consultant, (or in any other representative capacity) for any other person, firm, partnership, corporation or other entity (other than the Company), (i) with respect to the United States of America or Canada, engage in the discovery, research and/or development of therapeutic, diagnostic or prophylactic products which work through the same biological mechanisms as products which at the time of such termination are under active clinical or pre-clinical development or have been pre-clinically or clinically developed by the Company and which the Company has not abandoned ("Related Programs") or (ii) solicit or hire (or direct another to solicit or hire) the services of any employee of the Company or attempt to induce any such employee or any consultant to the Company to leave the employ of the Company (except when such acts are performed in good faith by the Employee on behalf of the Company). Notwithstanding the above, this provision shall not prevent or prohibit Employee from being employed during such one year period by another entity in a managerial role where Employee has overall responsibility for managing a research and development portfolio which includes one or more Related Programs, provided that Employee does not violate the terms of Section 6 hereof and does not during such one year term actively advise or direct the discovery, research or development efforts of such other entity in the Related Program(s). During the Employment Period, the Employee shall not own more than 2% of the outstanding common stock of any corporation. The provisions of this Section 5 shall not be deemed to reduce in any way any other fiduciary, contractual or other legal obligation the Employee may have to the Company, including without limitation any obligation which may arise by virtue of any corporation law, securities law, patent or intellectual property law or right, the common law, other agreements with the Company or otherwise. For purposes of Section 5 of this Agreement, the term "solicit" shall mean any communication of any kind whatsoever, regardless of by whom initiated, inviting, encouraging, or requesting any person or entity to take or refrain from taking any action. (b) The Employee agrees to comply with the terms of set forth in the Proprietary Information and Inventions Agreement. (c) If at any time within twenty-four (24) months after the date on which the Employee exercises a Company stock option or stock appreciation right, or on which Company restricted stock vests, or on which income is realized by the Employee in connection with any other Company equity-based award (each of which events is a "Realization Event"), the Employee breaches any provision of Section 5(a) or 5(b) of the Agreement in more than a minor, deminimus or trivial manner that causes or is likely it cause, more than deminimus financial or reputational harm to the Company (and, if such breach is susceptible to cure, the Employee does not cure such breach and harm within ten (10) days after the Employee's receipt of written notice of such breach of the Company which specifies in reasonable detail the facts and circumstances claimed to be the basis for such breach), then (i) the Employee shall forfeit all of Employee's unexercised (including unvested) Neurogen Corporation stock options and restricted stock and (ii) any gain realized within the twenty-four (24) months prior to such breach from the exercise of any Company stock options or the vesting of any Company restricted stock or other equity-based awards by the Employee from the Realization Event shall be paid by the Employee to the Company upon written notice from the Company within ninety (90) days of such notice (such payments may be made in increments over such period). Such gain shall be determined after reduction for any taxes paid (or, if such gain is determined before such taxes are paid, owing, provided that such taxes are actually paid in a timely manner) by the Employee which are attributable to such gain as of the date of the Realization Event, and without regard to any subsequent change in the Fair Market Value (as defined below) of a share of Company common stock; provided that any federal or state income tax benefit actually realized by the Employee as a result of making payments to the Company under this Section 5(c) (relating to any of the next ten (10) tax year periods) shall also be paid to the Company within fifteen (15) days of such realization. Such gain shall be paid by the Employee delivering to the Company shares of Company Common Stock with a Fair Market Value on the date of delivery equal to the amount of such gain. The Company shall have the right to offset such gain against any amounts otherwise owed to the Employee by the Company (whether as wages, vacation pay, or pursuant to any benefit plan or other compensatory arrangement). For purposes of this Section 5(c), the "Fair Market Value" of a share of Company Common Stock on any date shall be (i) the closing sale price per share of Company Common Stock during normal trading hours on the national securities exchange on which the Company Common Stock is principally traded for such date or the last preceding date on which there was a sale of such Company Common Stock on such exchange or (ii) if the shares of Company Common Stock are then traded on the NASDAQ Stock Market or any other over-the-counter market, the average of the closing bid and asked prices for the shares of Company Common Stock during normal trading hours in such over-the-counter market for such date or the last preceding date on which there was a sale of such Company Common Stock in such market, or (iii) if the shares of Company Common Stock are not then listed on a national securities exchange or traded in an over-the-counter market, such value as the Compensation Committee, in its sole discretion, shall reasonably determine. In the event that the Company seeks to enforce the provisions of this Section 5(c), and such enforcement is contested by the Employee, and it is finally determined that the Employee is not subject to the provisions of this Section 5(c), then the Company shall (i) reimburse the Employee for reasonable attorneys' fees incurred by the Employee in connection with such contest; and (ii) pay to the Employee an additional amount equal to one (1) times the amount in clause (i); provided that such payment under this clause (ii) shall not exceed $250,000. (d) Any termination of the Employee's employment or of this Agreement shall have no effect on the continuing operation of this Section 5. (e) The Employee acknowledges and agrees that the Company will have no adequate remedy at law, and could be irreparably harmed, if the Employee breaches or threatens to breach any of the provisions of this Section 5. The Employee agrees that the Company shall be entitled to equitable and/or injunctive relief to prevent any breach or threatened breach of this Section 5, and to specific performance of each of the terms hereof in addition to any other legal or equitable remedies that the Company may have. The Employee further agrees that Employee shall not, in any equity proceeding relating to the enforcement of the terms of this Section 5, raise the defense that the Company has an adequate remedy at law. (f) The terms and provisions of this Section 5 are intended to be separate and divisible provisions and if, for any reason, any one or more of them is held to be invalid or unenforceable, neither the validity nor the enforceability of any other provision of this Agreement shall thereby be affected. The parties hereto acknowledge that the potential restrictions on the Employee's future employment imposed by this Section 5 are reasonable in both duration and geographic scope and in all other respects. If for any reason any court of competent jurisdiction shall find any provisions of this Section 5 unreasonable in duration or geographic scope or otherwise, the Employee and the Company agree that the restrictions and prohibitions contained herein shall be effective to the fullest extent allowed under applicable law in such jurisdiction. (g) The parties acknowledge that this Agreement would not have been entered into and the benefits described in Section 4 of this Agreement would not have been promised in the absence of the Employee's promises under this Section 5. 6. CONFIDENTIAL INFORMATION The Employee agrees to substantially comply with the terms set forth in the Proprietary Information and Inventions Agreement between the Employee and the Company, a copy of which is attached hereto as Exhibit A and incorporated by reference herein. 7. TERMINATION (a) Termination by the Company for Cause The Company may terminate the Employee's employment hereunder for cause. If the Company terminates the Employee's employment hereunder for cause, the Employment Period shall end and the Employee shall only be entitled to any Base Salary accrued or annual bonus awarded and earned but not yet paid as of the date of termination of the Employee's employment with the Company. If the Employee's employment is to be terminated for cause, the Company shall give written notice of such termination to the Employee. Such notice shall specify the particular act or acts, or failure to act, which is or are the basis for the decision to so terminate the Employee's employment for cause. (b) Termination Without Cause or Termination For Good Reason The Company may terminate the Employee's employment hereunder without cause and the Employee may terminate Employee's employment hereunder for good reason. If the Company terminates the Employee's employment hereunder without cause, or if the Employee terminates Employee's employment hereunder for good reason, the Employment Period shall end and the Employee shall only be entitled to (i) any Base Salary accrued or annual bonus awarded and earned but not yet paid as of the actual date of termination of the Employee's employment with the Company; (ii) a lump sum payment in an amount equal to the Employee's annual Base Salary as provided in Section 4(a) above; (iii) continuation of the health and welfare benefits of the Employee, as set forth in Section 4(c) above, or the economic equivalent thereof, at the same cost and level in effect on the date of termination of the Employee's employment with the Company for one (1) year after such date of termination; and (iv) the right to exercise immediately any stock options and to freely trade any restricted stock granted to the Employee which, but for such termination, would have become exercisable or tradable, as the case may be, within one year of the date of such termination without cause or for good reason. If the Employee's employment is to be terminated without cause, the Company shall give the Employee thirty (30) days prior written notice of its intent to so terminate the Employee's employment. If the Employee intends to terminate Employee's employment for good reason, the Employee agrees to give the Company at least thirty (30) days prior written notice. (c) Termination Due to Death or Disability The Company may terminate the Employee's employment hereunder due to the Employee's inability to render, for a period of three consecutive months or an aggregate of any on hundred twenty (120) days within any six (6) month period, services hereunder by reason of permanent disability, as determined by the written medical opinion of an independent medical physician selected in good faith by the Company ("Disability"). In the event of the Employee's death or a termination of the Employee's employment by the Company due to Disability, the Employment Period shall end and the Employee, Employee's estate or Empoyee's legal representative, as the case may be, shall only be entitled to (i) (a) any Base Salary accrued or annual bonus awarded and earned but not yet paid as of the actual date of termination of the Employee's employment with the Company, and (b) any other compensation and benefits as may be provided in accordance with the terms and provisions of any applicable plans and programs of the Company; and (ii) in the case of Disability, (a) continuation of payment of the Employee's Base Salary, as set forth in Section 4(a) above, until the Employee commences to receive payments under the Company's long-term disability plan, (b) continuation of the health and welfare benefits of the Employee, as set forth in Section 4(c) above, or the economic equivalent thereof, at the same cost and level in effect on the date of termination for one (1) year after the date of termination and (c) the right to exercise immediately that proportion of the stock options (rounded up to the nearest whole number of shares) granted to the Employee which would become exercisable on or before the May 13 immediately following the date of termination of the Employee's employment with the Company due to Disability which is equal to the number of days worked by the Employee from, but excluding, the May 13 immediately preceding such termination date to, and including, such termination date divided by 365 days. (d) Voluntary Termination The Employee may affect a Voluntary Termination of Employee's employment with the Company hereunder. A "Voluntary Termination" shall mean a termination of employment by the Employee on Employee's own initiative other than a termination due to death or Disability or a termination for good reason. A Voluntary Termination shall not be, and shall not be deemed to be, a breach of this Agreement and shall result in the end of the Employment Period and only entitle the Employee to all of the rights and benefits which the Employee would be entitled in the event of a termination of the Employee's employment by the Company for cause. (e) Termination by the Company at End of Employment Period Notwithstanding any provision of this Agreement to the contrary, if (a) the Employment Period (i) is not terminated early under Sections 7(a), 7(b), 7(c) or 7(d) above and (ii) the Company provides written notice to the Employee, pursuant to Section 2 above, that it does not wish to extend or further extend the Employment Period, and (b) the Employee's employment with the Company is subsequently terminated at the end of the Employment Period, the Employee shall be entitled to (x) continuation of payment of the Employee's Base Salary, as provided in Section 4(a) above, as of the date of termination of the Employee's employment with the Company for a period equal to (1) one year less the number of days notice given by the Company to the Employee that it does not wish to extend or further extend the Employment Period (such notice period shall be deemed to commence as of the date of such written notice by the Company); (y) continuation of the health and welfare benefits of the Employee, as set forth in 4(c) above, or the economic equivalent thereof, at the same cost and level in effect on the date of termination of the Employee's employment with the Company for one (1) year after such termination; and (z) the right to exercise immediately any stock options and to trade freely any restricted stock granted to the Employee which, but for such termination, would have become exercisable or freely tradable, as the case may be, on or before the May 13 immediately following the date on which the one (1) year period referred to the preceding subclause (x) ends; provided, however, that the severance payment by the Company to the Employee under subclause (x) of this Section 7(e) shall be offset on a dollar for dollar basis by any cash, or the fair market value of any non-cash, remuneration, benefit or other entitlement earned, received or receivable by the Employee in connection with the employment of such Employee in any capacity, other than dividends, interest income or other passive investment income earned as a result of an interest in a business or entity of which the Employee owns less than 2% of the beneficial ownership. If the Employee shall be entitled to any such severance payment from the Company after the termination of the Employment Period, the Employee shall have the obligation to notify the Company of any employment, consultation or other activity which may involve any remuneration, benefits or other entitlements as described above, and as to which the Company may be entitled to an offset. 8. SURVIVAL The rights and obligations of the parties hereunder shall survive the termination of the Employee's employment hereunder and the termination of this Agreement to the extent necessary to the intended preservation of such rights and obligations. 9. WHOLE AGREEMENT AND MODIFICATION This Agreement sets forth the entire agreement and understanding of the parties with respect to the subject matter contained herein, and supersedes all prior and existing agreements, whether written or oral, between them concerning the subject matter contained herein. This Agreement may be modified only by a written agreement executed by each party to this Agreement. 10. NOTICES Any notice or other communication required or permitted to be given under this Agreement shall be in writing and shall be mailed by certified mail, return receipt requested, or delivered against receipt to the party to whom it is to be given at the address of such party set forth above or to such other address as the party shall have furnished in writing in accordance with this provision. Notice to the estate of the Employee shall be sufficient if addressed to the Employee in accordance with this provision. Any notice or other communication given by certified mail shall be deemed given three (3) days after posting. However, a notice changing a party's address shall be deemed given at the time of the receipt of the notice. 11. WAIVER Any waiver by either party of a breach of any provision of this Agreement shall not operate as or be construed to be a waiver of any other breach of such provision or of any breach of any other provision of this Agreement. The failure of a party to insist upon strict adherence to any term of this Agreement on one or more occasions shall not be considered a waiver or deprive that party of the right thereafter to insist upon strict adherence to that term or any other term of this Agreement. Any waiver must be in writing, signed by the party giving such waiver. 12. SUCCESSORS (a) Effect on Employee This Agreement is personal to the Employee and, without the prior express written consent of the Company, shall not be assignable by the Employee, except that the Employee's rights to receive any compensation or benefits under this Agreement may be transferred or disposed of pursuant to testamentary disposition, intestate succession or pursuant to a domestic relations order of a court of competent jurisdiction. This Agreement shall inure to the benefit of and be enforceable by the Employee's heirs, beneficiaries and/or legal representatives. (b) Effect on Company This Agreement shall inure to the benefit of and be binding on the Company and its successors and assigns. The Company shall reasonably require any successor to all or substantially all of the business and/or assets of the Company, whether direct or indirect, by purchase, merger, consolidation, acquisition of stock, or otherwise, by an agreement in form and substance reasonably satisfactory to the Employee, expressly to assume and agree to perform this Agreement in the same manner and to the same extent as the Company would be required to perform if no such succession had taken place. 13. NO THIRD PARTY BENEFICIARIES This Agreement does not create, and shall not be construed as creating, any rights enforceable by any person not a party to this Agreement except as provided in Section 12 of this Agreement. 14. COUNTERPARTS This Agreement may be executed in any number of counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. 15. GOVERNING LAW This Agreement shall be governed by and construed in accordance with the laws of the State of Connecticut, without giving effect to the principles of conflict of laws thereof. 16. SEVERABILITY The invalidity or unenforceability of any provision of this Agreement shall not affect the validity or enforceability of any other provision of this Agreement. 17. NO VIOLATION OF OUTSTANDING AGREEMENT(S) Employee hereby warrants that the execution of this Agreement and the performance of his duties hereunder do not and will not violate any agreement with any other person or entity. IN WITNESS WHEREOF, the parties have duly executed this Agreement which shall be effective as of the effective date noted above. NEUROGEN CORPORATION By: /s/ STEPHEN R. DAVIS --------------------------- /s/ EDMUND P. HARRIGAN ------------------------------- Edmund P. Harrigan, M.D. EXHIBIT 10.2 NEUROGEN CORPORATION PROPRIETARY INFORMATION AND INVENTIONS AGREEMENT This Agreement shall be effective as of the date executed as indicated below (the "Effective Date") I recognize that Neurogen Corporation, a Delaware corporation, together with its subsidiaries, (hereinafter collectively called the "Company") is engaged in a continuous program of research and development as part of its business, present and future, including the generation of new inventions, (patentable or not) and other trade secret information, which I understand constitutes one of the most valuable assets of the Company and must be treated as such and: I further understand and agree that: A. As part of my employment by the Company I am (or may be) expected to make new contributions and inventions that may constitute important trade secrets: B. The Company possesses and will continue to possess information that has been created, discovered, developed, or otherwise become known to the Company (including information created, discovered, developed, or made known by me during the period of or arising out of my employment by the Company) or in which property rights have been assigned or otherwise conveyed to the Company, which information has commercial value in the business in which the Company is engaged or relates to the Company's actual or demonstrably anticipated business or research and development activities. All such information is hereinafter referred to as "Proprietary Information." By way of illustration, but not limitation, Proprietary Information includes trade secrets (which may further include any of the following); and also includes computer programs and modeling strategies; marketing plans; strategies; unpublished financial statements; forecasts; employee, customer, collaborator and supplier lists and information; improvements; inventions; formulas; chemical structures and structure activity relationships, chemical or biological processes; techniques; assays; know-how; data; organisms; plasmids; expression vectors and the like. Proprietary Information does not include information that: (i) is in or becomes a part of the public domain (other than through unauthorized disclosure by me); (ii) is disclosed by the Company to third parties free of any obligation of confidentiality; (iii)is learned outside the scope of my employment from an outside source that is not under any obligation of confidentiality with respect to such information to the Company or any of its business partners. C. My employment creates a relationship of confidence and trust between me and the Company with respect to all Proprietary Information or any other information that is: (1) applicable to the business of the Company; or (2) applicable to the business of any business partner of the Company, which information may be made known to me by the Company or by any business partner of the Company, or learned by me in the course of my employment; or (3) applicable to the valuation of the Company's Common Stock, which information could affect the stock's price, sales, or purchases. D. As used in this Agreement, the period of my employment includes any time during which I may be retained by the Company as a consultant. In consideration of my employment and the compensation to be received by me from the Company from time to time, I hereby agree as follows: 1. All Proprietary Information shall be the sole property of the Company and its assigns, and the Company and its assigns shall be the sole owners of all patents and other rights in connection with such Proprietary Information. At all times, both during my employment by the Company and after its termination, I will keep in confidence and trust all Proprietary Information and I will not use or disclose any Proprietary Information or anything relating to such information without the prior written consent of the Company, except as may be necessary in the ordinary course of performing my duties as an employee of the Company. 2. I agree that at no time will I reveal to any third party Proprietary Information or other information not available to the general public that could cause a third party or other parties relying on this information to purchase or sell the Company stock. 3. I agree that at no time will I purchase or sell Company stock based on Proprietary Information or on any other information not known to the general public. 4. I agree that during the period of my employment by the Company I will not, without the prior written consent of the Company, engage in any employment or activity, either as an individual proprietor, partner, stockholder, officer, employee, director, consultant, or in any other capacity whatsoever (except as the holder of not more than 1% of the total outstanding stock of a publicly held company), for any profit or non-profit institution which competes with the Company or involves either the business in which the Company is engaged or its actual or demonstrably anticipated research and development. 5. I shall not at any time, during or for two (2) years after the term of my employment by the Company, recruit or otherwise solicit or induce any employee(s) of the Company to terminate their employment with, or otherwise cease their relationship(s) with, the Company. 6. During the term of my employment with the Company, I will keep and maintain adequate and current written records of all Proprietary Information (in the form of notes, sketches, drawings, on paper and in computer files as may be specified by the Company), which records in any form shall be available to and remain the sole property of the Company at all times. I agree that I will not, at any time, remove from the Company's premises such records and related documents, prepared by me or any other employee of the Company, without the Company's prior written consent. 7. In the event of the termination of my employment by me or by the Company for any reason whatsoever, I will promptly deliver to the Company all notes, documents, reports and data of any nature pertaining to my work with the Company. I understand that all such documents and information are the exclusive property of the Company, and I will not, without the prior written consent of the Company, take with me upon the termination of my employment any documents or data, or any reproduction thereof, containing or pertaining to any Proprietary Information. 8. Except as otherwise provided in paragraph 13(b) of this Agreement, I will promptly and fully disclose to the Company, or any persons designated by it, all improvements, inventions, formulas, chemical structures and structure activity relationships, processes, techniques, assays, computer programs and modeling strategies, original works of authorship, know-how, data, organisms, plasmids, expression vectors and the like, whether or not patentable, made or conceived or reduced to practice or learned by me, either alone or jointly with others, during the period of my employment, knowledge of which: (a) is related to or useful in the business of the Company, including, but not limited to drug discovery, research, development and commercialization and other pharmaceutical and biomedical activities generally or any other of its actual or demonstrably anticipated business, research and development activities; or (b) result from tasks assigned to me by the Company; or (c) result from use of Proprietary Information, equipment, supplies or facilities of the Company or property contained on premises owned, leased, or contracted for by the Company. All such improvements, inventions, formulas, chemical structures and structure activity relationships, processes, techniques, assays, computer programs and modeling strategies, know-how, data, organisms, plasmids, expression vectors and the like are hereinafter referred to as "Inventions". All such original works of authorship are hereinafter referred to as "Works." 9. (a) Subject to paragraph 9(c) below, I agree that all Inventions shall be the sole property of the Company and its assigns, and that the Company and its assigns shall be the sole owners of all patents and other rights in connection with such Inventions. I hereby assign to the Company, its successors and assigns, any rights I may have or acquire in any country in such Inventions. I further agree that all such Works which are protectable by copyright are "works made for hire," as that term is defined in the United States Copyright Act and assign all rights in such Works to the Company. (b) I further agree as to all such Inventions to assist the Company in every proper way, without any additional charge (but at the Company's expense) to obtain and from time to time enforce patents, copyrights and other forms of legal protection for such Inventions in any and all countries. To that end I will execute all documents for use in applying for and obtaining patents, copyrights and other forms of legal protection for such Inventions, and I will take any steps reasonably deemed necessary by the Company to enforce such rights and protections, as the Company may desire, together with any assignments of them to the Company or persons designated by it. My obligation to assist the Company in obtaining and enforcing patents, copyrights and other legal protections for such Inventions in any and all countries shall continue after the termination of my employment, but, at my written request, the Company shall compensate me at a reasonable rate after my termination for time (other than the time required to execute documents for use in applying for and obtaining patents, copyrights and other forms of legal protection) that I spend at the Company's request on such assistance. If the Company is unable because of my mental or physical incapacity or for any other reason to secure my signature to apply for or to pursue any application of any United States or foreign patents or copyright registrations covering Inventions or original works of authorship assigned to the Company, then I hereby irrevocably designate and appoint the Company and its duly authorized officers and agents as my agent and attorney in fact, to act for and in my behalf and stead to execute and file any such applications and to do all other lawfully permitted acts in the United States or any other country to further the prosecution and issuance of letters patent or copyright registrations thereon with the same legal force and effect as if executed by me. (c) I understand that paragraph 9(a) does not apply to Inventions or Works for which no equipment, supplies, facility or trade secret information of the Company was used, that were developed entirely on my own time and without using any of the Company's equipment, supplies or facilities or any property contained on premises owned, leased, or contracted for by the Company and that do not relate to any work performed by me for the Company or otherwise to the business of the Company, including, but not limited to drug discovery, research development and commercialization and other pharmaceutical and biomedical research generally, or to the Company's actual or demonstrably anticipated business, research or development activities. (d) I further agree that, if I claim to have conceived any Invention(s) within a six (6) month period following termination of my employment by the Company, the burden of proving conception after such termination shall be on me, and not on the Company. 10. As a matter of record I have identified on Exhibit A attached to this Agreement all inventions or improvements relevant to the business of the Company or its actual or demonstrably anticipated research and development that were made or conceived or first reduced to practice by me alone or jointly with others prior to my employment by the Company, for which patent applications have not yet been filed as of the Execution Date. The inventions and improvements I have designated on Exhibit A shall be removed from the operation of this Agreement. I represent and warrant that such list is complete. If there are no inventions or improvements designated to be removed from the operation of the Agreement on Exhibit A, I represent and warrant that there are no such inventions and improvements at the time of signing this Agreement. In consideration of my becoming employed by the Company, I hereby assign to the Company any rights I may have or acquire in any inventions or improvements not so designated in Exhibit A that are relevant to the business of the Company, including but not limited to drug discovery and other pharmaceutical and biomedical research generally or any other of its actual or demonstrably anticipated business research and development activities, that were made or conceived or first reduced to practice by me alone or jointly with others prior to my employment by the Company. 11. I understand that the Company has received, and in the future will receive, confidential or proprietary information from third parties ("Third Party Information"). I further understand that the Company is under a duty to maintain the confidentiality of such information and to use it only for certain limited purposes. During the term of my employment and thereafter, I will hold Third Party Information in the strictest confidence and will not disclose or use Third Party Information except as permitted by the agreement between the Company and such third party, unless expressly authorized in writing to act otherwise by an officer of the Company. 12. I represent that the performance of my duties under this Agreement and as an employee of the Company does not and will not breach any agreement to keep in confidence Proprietary Information acquired by me in confidence or in trust prior to my employment by the Company. I have not entered into, and I agree I will not enter into, any agreement, either written or oral, in conflict with this Agreement. I represent that I have provided the Company with a copy of any restrictive covenants, covenants not to compete, confidentiality agreements, non-disclosure agreements, assignment of invention agreements or any other contractual obligations between me and any other entity engaged in pharmaceutical or biomedical research. 13. (a) I understand that, as part of the consideration of the offer of employment extended to me by the Company, of my employment, or of my continued employment by the Company, I will not bring with me to the Company or use in the performance of my responsibilities at the Company any materials or documents of a former employer that are not generally available to the public, unless I obtain and submit to the Company written authorization from the former employer for the possession and use of such materials in the course of my employment by the Company, and the Company agrees to such bringing and use. The only materials or documents of a former employer that are not generally available to the public that I will bring to the Company or use in my employment are identified on Exhibit A attached to this Agreement. I represent that, prior to the effective date of my employment with the Company, I have obtained and submitted to the Company written authorization for the possession and use of each of such items, if any, listed on Exhibit A. (b) I also understand that, in my employment with the Company and in the performance of my duties under this Agreement, including paragraphs 8, 10 and 13(a), I am not to breach any obligation of confidentiality that I have to former employers or other third parties. I agree that I shall continue to fulfill all such obligations during my employment with the Company. 14. This Agreement shall be effective as of the Effective Date as so designated above, unless my first day of my employment by the Company precedes such date, in which case my first date of employment shall be considered the Effective Date. 15. This Agreement shall be binding upon me, my heirs, executors, assigns, and administrators, and shall inure to the benefit of the Company, its successors, and assigns. 16. I agree that in the event of a breach or threatened breach of the provisions of this Agreement, monetary damages would be inadequate to compensate the Company and, in addition to any other remedies or rights it may have, the Company shall be entitled to obtain an injunction or other equitable relief to enforce the terms of this Employee Agreement and shall be entitled to recover from me all costs (including reasonable attorneys' fees) incurred by the Company in establishing that breach and in otherwise enforcing any of the covenants or provisions of this Agreement. I further agree that no bond or other security shall be required in obtaining such injunction or other equitable relief and consent to the issuance of such injunction or other equitable relief and to the ordering of specific performance. 17. This Agreement will be governed by the laws of the State of Connecticut, where not superceded by federal law, and the parties expressly consent to the exclusive and personal jurisdiction of the state and federal courts located in the State of Connecticut for any claims relating to this Agreement or otherwise arising from my employment with the Company. If any provision in this Agreement is determined to be in violation of any law, rule or regulation or otherwise unenforceable, and cannot be modified to be enforceable, such determination shall not affect the validity of any other provision of this Agreement, but such other provisions shall remain in full force and effect. Each provision, paragraph and subparagraph of this Agreement is severable from every other provision, paragraph and subparagraph and constitutes a separate and distinct covenant. If the scope or enforceability of this Agreement is in any way disputed at any time, a court shall modify and enforce the Agreement to the extent it believes to be reasonable under the circumstances. 18. Except as may be expressly provided in a separate signed written agreement between the Company and me, my employment is "at will" and the Company or I may terminate my employment at any time with or without cause. There are no representations or promises that my employment will continue for a set period of time, nor are there any representations or promises that my employment will be terminated only under particular circumstances. I understand that the nature of this relationship may only be changed by an express written agreement signed by a duly authorized officer of the Company and me. 19. This Agreement constitutes the entire agreement and understanding between the Company and me concerning the subject matters contained herein and, from the Effective Date, supersedes any and all prior understandings and agreements between the parties concerning these subject matters; provided, that any such prior agreement(s) shall concurrently continue in full force and effect with respect to any Proprietary Information or other confidential information disclosed prior to the Effective Date. This Agreement may not be modified, terminated, waived altered or amended except in a writing signed by me and a duly authorized officer of the Company. This Agreement is intended to supplement and not replace or reduce any rights the Company may have under the Connecticut Uniform Trade Secrets Act or other applicable intellectual property laws. Dated: __________________________ By: __________________________ WITNESSED, ACCEPTED AND AGREED TO: NEUROGEN CORPORATION By: ___________________________ Title: _________________________ EXHIBIT A Neurogen Corporation 35 Northeast Industrial Road Branford, Connecticut 06405 1. The following is a complete list of all Inventions relevant to the subject matter of the Proprietary Information and Inventions Agreement regarding my employment by Neurogen (the "Company") that have been made or conceived or first reduced to practice by me alone or jointly with others prior to my employment by the Company, for which patent applications have not yet been filed as of the Execution Date. I desire to remove these inventions and improvements listed, if any, from the operation of the Company's Proprietary Information and Inventions Agreement. _______ No inventions or improvements. _______ See below: ----------------------------------------------------------------------- ----------------------------------------------------------------------- ----------------------------------------------------------------------- ----------------------------------------------------------------------- ______ Additional sheets attached. Dated:_______________________ By:_________________________________________ 2. I propose to bring to my employment the following materials and documents of a former employer that are not generally available to the public, which materials and documents may be used in employment. ______ No materials and documents. ______ See below: ----------------------------------------------------------------------- ----------------------------------------------------------------------- ----------------------------------------------------------------------- ----------------------------------------------------------------------- ______ Additional sheets attached. My signature below confirms that my continued use and possession of these materials and documents, if any, are authorized by my former employer. Dated :_____________________ By: _______________________________________